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ALL HEAVY CHAIN VARIABLE DOMAINS FROM KABAT DATABASE COMBINED
Heavy chains subgroup I (A) V region - Mouse
Heavy chains subgroup I (B) V region - Mouse
Heavy chains subgroup II (A) V region - Mouse
Heavy chains subgroup II (B) V region - Mouse
Heavy chains subgroup II (C) V region - Mouse
Heavy chains subgroup III (A) V region - Mouse
Heavy chains subgroup III (B) V region - Mouse
Heavy chains subgroup III (C) V region - Mouse
Heavy chains subgroup III (D) V region - Mouse
Heavy chains subgroup V (A) V region - Mouse
Heavy chains subgroup V (B) V region - Mouse
Heavy chains subgroup misc. V region - Mouse
Heavy chains subgroup I V region - Human
Heavy chains subgroup II V region - Human
Heavy chains subgroup III V region - Human
Heavy chains V region - Rat
Heavy chains V region - Rabbit
Heavy chains V region - Guinea pig
Heavy chains V region - Cat
Heavy chains V region - Dog
Heavy chains V region - Chicken
Heavy chains V region
+--- Position
|
| +--- Number of observations (not counting gaps)
| |
| | +--- Residue type
| | |
V V V v--- Observed frequency in sample
1 ( 1410): E:0.584 Q:0.318 D:0.070 A:0.017 G:0.004 K:0.003
2 ( 1357): V:0.896 -:0.036 I:0.029 E:0.014 M:0.007 S:0.006
3 ( 1414): Q:0.675 K:0.196 T:0.033 S:0.031 H:0.017 M:0.013
4 ( 1426): L:0.964 V:0.028 F:0.002 A:0.001 D:0.001 H:0.001
5 ( 1437): Q:0.400 V:0.347 L:0.072 K:0.069 E:0.052 D:0.029
6 ( 1424): E:0.580 Q:0.400 A:0.004 R:0.004 D:0.003 G:0.002
7 ( 1437): S:0.878 P:0.086 T:0.019 W:0.004 X:0.003 V:0.002
8 ( 1439): G:0.954 E:0.023 S:0.006 V:0.004 A:0.003 D:0.003
9 ( 1447): G:0.451 P:0.270 A:0.227 S:0.023 T:0.020 D:0.002
10 ( 1454): G:0.485 E:0.368 D:0.041 V:0.032 S:0.027 R:0.020
11 ( 1467): L:0.892 V:0.070 T:0.012 F:0.007 I:0.007 S:0.005
12 ( 1442): V:0.859 K:0.045 A:0.019 I:0.015 M:0.015 Q:0.013
13 ( 1402): K:0.487 Q:0.321 R:0.092 A:0.035 T:0.035 E:0.010
14 ( 1468): P:0.913 A:0.041 S:0.024 L:0.011 T:0.007 G:0.002
15 ( 1461): G:0.812 S:0.153 T:0.010 E:0.005 K:0.005 R:0.003
16 ( 1447): G:0.352 A:0.262 Q:0.136 S:0.084 E:0.053 R:0.046
17 ( 1531): S:0.869 T:0.081 P:0.020 A:0.013 G:0.003 L:0.003
18 ( 1539): L:0.521 V:0.401 M:0.035 R:0.019 H:0.010 I:0.003
19 ( 1529): K:0.554 R:0.220 S:0.154 T:0.041 Q:0.009 G:0.007
20 ( 1560): L:0.644 I:0.176 M:0.131 V:0.040 T:0.003 R:0.001
21 ( 1517): S:0.773 T:0.197 V:0.015 A:0.003 L:0.003 I:0.002
22 ( 1489): C:0.998 K:0.001 R:0.001 S:0.001
23 ( 1509): K:0.394 A:0.293 T:0.187 S:0.047 V:0.040 E:0.021
24 ( 1505): A:0.650 V:0.174 T:0.120 G:0.024 I:0.011 F:0.007
25 ( 1514): S:0.910 T:0.070 A:0.006 Y:0.005 F:0.003 G:0.002
26 ( 1466): G:0.980 D:0.006 E:0.005 V:0.002 A:0.001 R:0.001
27 ( 1451): F:0.484 Y:0.422 D:0.037 G:0.023 I:0.011 S:0.006
28 ( 1491): T:0.623 S:0.215 N:0.047 D:0.041 A:0.027 I:0.014
29 ( 1508): F:0.759 L:0.109 I:0.101 V:0.018 S:0.005 T:0.003
30 ( 1495): T:0.505 S:0.411 K:0.039 N:0.015 G:0.007 I:0.005
31 ( 1475): S:0.475 D:0.251 N:0.081 G:0.054 T:0.054 R:0.044
32 ( 1486): Y:0.664 F:0.110 S:0.050 T:0.036 G:0.036 D:0.031
33 ( 1479): Y:0.320 W:0.218 G:0.211 A:0.078 T:0.032 N:0.024
34 ( 1469): M:0.606 I:0.194 V:0.081 W:0.042 A:0.022 Y:0.019
35 ( 1455): H:0.258 N:0.246 S:0.197 E:0.087 Y:0.034 W:0.027
35a( 97): -:0.932 N:0.021 W:0.015 V:0.008 C:0.006 S:0.006
35b( 38): -:0.973 N:0.008 S:0.008 G:0.006 X:0.003 A:0.001
36 ( 1454): W:0.992 R:0.003 C:0.001 A:0.001 K:0.001 M:0.001
37 ( 1392): V:0.869 I:0.108 A:0.006 L:0.006 M:0.005 F:0.003
38 ( 1421): R:0.583 K:0.387 C:0.005 M:0.004 Q:0.004 N:0.004
39 ( 1393): Q:0.941 K:0.035 E:0.007 R:0.004 I:0.002 H:0.001
40 ( 1402): R:0.290 A:0.231 P:0.171 S:0.133 T:0.069 F:0.056
41 ( 1376): P:0.886 H:0.072 S:0.017 T:0.008 N:0.005 A:0.004
42 ( 1357): G:0.825 E:0.133 S:0.009 A:0.007 D:0.007 R:0.007
43 ( 1388): K:0.591 Q:0.262 R:0.061 N:0.051 H:0.019 E:0.007
44 ( 1332): G:0.676 R:0.109 S:0.085 K:0.053 A:0.053 T:0.012
45 ( 1392): L:0.976 P:0.011 F:0.004 Q:0.002 G:0.001 R:0.001
46 ( 1383): E:0.942 Q:0.021 K:0.018 D:0.008 A:0.003 G:0.001
47 ( 1352): W:0.923 Y:0.033 L:0.018 F:0.011 H:0.004 S:0.002
48 ( 1373): I:0.554 V:0.198 L:0.144 M:0.097 S:0.004 W:0.001
49 ( 1384): G:0.712 A:0.228 S:0.042 V:0.007 T:0.004 E:0.002
50 ( 1409): Y:0.200 R:0.123 V:0.101 A:0.096 E:0.089 D:0.060
51 ( 1416): I:0.884 S:0.054 T:0.015 L:0.011 F:0.009 V:0.008
52 ( 1409): N:0.285 S:0.142 Y:0.136 R:0.123 D:0.113 W:0.080
52a( 1130): P:0.449 -:0.202 N:0.117 S:0.082 Y:0.028 G:0.025
52b( 214): -:0.846 K:0.135 R:0.008 G:0.004 N:0.003 I:0.001
52c( 197): -:0.858 A:0.087 S:0.025 T:0.009 V:0.006 P:0.006
53 ( 1382): G:0.255 N:0.207 Y:0.129 S:0.118 D:0.089 A:0.077
54 ( 1408): N:0.269 G:0.267 S:0.226 D:0.140 K:0.030 T:0.023
55 ( 1403): G:0.612 S:0.145 Y:0.130 D:0.043 V:0.016 A:0.011
56 ( 1420): S:0.232 Y:0.173 T:0.161 G:0.128 N:0.086 D:0.082
57 ( 1425): T:0.771 I:0.102 P:0.022 S:0.020 A:0.018 K:0.018
58 ( 1430): N:0.224 Y:0.190 K:0.164 E:0.099 S:0.071 D:0.051
59 ( 1433): Y:0.946 F:0.020 I:0.007 N:0.006 H:0.004 S:0.003
60 ( 1433): N:0.481 A:0.202 S:0.124 P:0.057 T:0.049 D:0.034
61 ( 1439): E:0.268 P:0.173 D:0.153 Q:0.138 A:0.134 S:0.083
62 ( 1442): K:0.396 S:0.374 A:0.087 T:0.038 W:0.028 N:0.024
63 ( 1443): F:0.466 V:0.278 L:0.194 A:0.022 I:0.013 M:0.009
64 ( 1428): K:0.776 Q:0.091 M:0.041 I:0.019 R:0.018 N:0.015
65 ( 1394): G:0.608 S:0.237 D:0.088 N:0.024 T:0.012 R:0.011
66 ( 1431): R:0.548 K:0.428 Q:0.011 G:0.007 P:0.002 E:0.001
67 ( 1453): F:0.343 A:0.320 T:0.103 L:0.088 V:0.067 I:0.056
68 ( 1456): T:0.740 S:0.124 I:0.091 A:0.016 F:0.008 K:0.005
69 ( 1470): I:0.511 L:0.362 V:0.059 F:0.031 M:0.024 T:0.007
70 ( 1472): T:0.513 S:0.445 N:0.012 F:0.010 I:0.008 L:0.005
71 ( 1472): R:0.399 V:0.302 A:0.126 K:0.101 S:0.024 L:0.020
72 ( 1451): D:0.924 E:0.021 N:0.019 T:0.012 K:0.008 S:0.007
73 ( 1461): K:0.308 N:0.297 T:0.292 D:0.057 S:0.018 E:0.010
74 ( 1476): S:0.774 A:0.099 P:0.049 G:0.023 T:0.018 N:0.017
75 ( 1459): S:0.416 K:0.348 Q:0.112 T:0.028 A:0.022 R:0.020
76 ( 1408): S:0.565 N:0.354 T:0.023 K:0.016 G:0.007 R:0.007
77 ( 1413): T:0.661 Q:0.141 I:0.100 S:0.036 N:0.012 K:0.009
78 ( 1455): A:0.438 L:0.282 V:0.174 F:0.055 Y:0.025 G:0.006
79 ( 1473): Y:0.756 F:0.134 S:0.035 D:0.018 H:0.018 R:0.011
80 ( 1486): L:0.576 M:0.386 F:0.016 I:0.007 T:0.005 V:0.003
81 ( 1479): Q:0.721 K:0.120 E:0.093 S:0.010 T:0.010 D:0.009
82 ( 1486): L:0.531 M:0.405 I:0.038 S:0.007 V:0.007 W:0.007
82a( 1444): S:0.380 N:0.377 R:0.128 T:0.053 L:0.014 D:0.008
82b( 1472): S:0.733 N:0.078 A:0.066 K:0.029 T:0.027 G:0.025
82c( 1479): L:0.825 V:0.131 M:0.017 -:0.015 P:0.009 G:0.001
83 ( 1476): T:0.521 R:0.281 Q:0.080 K:0.074 A:0.012 D:0.010
84 ( 1512): S:0.558 A:0.213 T:0.140 P:0.036 N:0.018 V:0.011
85 ( 1496): E:0.820 D:0.097 A:0.042 S:0.009 N:0.008 V:0.007
86 ( 1400): D:0.980 E:0.008 N:0.003 A:0.003 G:0.002 T:0.001
87 ( 1506): T:0.562 S:0.409 M:0.011 A:0.007 P:0.003 F:0.002
88 ( 1618): A:0.947 G:0.040 V:0.004 P:0.003 T:0.002 L:0.001
89 ( 1590): V:0.431 T:0.283 I:0.107 M:0.105 L:0.053 R:0.009
90 ( 1619): Y:0.989 F:0.004 H:0.002 L:0.001 A:0.001 G:0.001
91 ( 1682): Y:0.787 F:0.202 H:0.004 C:0.002 N:0.001 S:0.001
92 ( 1687): C:0.995 S:0.002 A:0.001 M:0.001 P:0.001 V:0.001
93 ( 1676): A:0.846 T:0.078 V:0.026 G:0.016 S:0.012 M:0.009
94 ( 1668): R:0.810 K:0.045 S:0.031 T:0.025 G:0.023 P:0.013
95 ( 1450): D:0.197 G:0.145 S:0.128 Y:0.100 E:0.063 R:0.053
96 ( 1346): Y:0.194 G:0.170 R:0.081 D:0.061 S:0.052 A:0.050
97 ( 1318): Y:0.312 G:0.176 -:0.060 D:0.054 L:0.053 N:0.047
98 ( 1188): Y:0.268 G:0.184 -:0.141 D:0.055 S:0.054 L:0.045
99 ( 1056): -:0.233 G:0.202 Y:0.141 S:0.107 R:0.047 D:0.038
100 ( 857): -:0.371 S:0.134 G:0.125 Y:0.096 D:0.038 W:0.035
100a( 658): -:0.511 S:0.120 Y:0.101 G:0.071 D:0.027 R:0.024
100b( 482): -:0.638 Y:0.108 S:0.044 G:0.043 W:0.040 R:0.020
100c( 293): -:0.778 Y:0.051 S:0.036 G:0.034 D:0.016 W:0.014
100d( 183): -:0.859 Y:0.028 G:0.018 D:0.012 S:0.011 V:0.008
100e( 126): -:0.903 Y:0.035 G:0.012 A:0.010 P:0.006 S:0.005
100f( 91): -:0.930 Y:0.019 C:0.005 D:0.005 P:0.005 G:0.005
100g( 60): -:0.954 Y:0.015 G:0.009 Q:0.003 V:0.003 D:0.002
100h( 41): -:0.968 Y:0.008 T:0.005 D:0.004 A:0.003 G:0.003
100i( 37): -:0.971 A:0.009 Y:0.005 G:0.003 X:0.002 L:0.002
100j( 906): Y:0.315 -:0.305 A:0.163 W:0.070 G:0.026 F:0.021
100k( 1152): F:0.577 M:0.173 -:0.126 L:0.042 V:0.018 S:0.012
101 ( 1278): D:0.704 A:0.166 -:0.034 N:0.013 I:0.013 V:0.011
102 ( 1307): Y:0.712 V:0.167 S:0.021 F:0.020 H:0.017 I:0.015
103 ( 1274): W:0.980 A:0.005 L:0.004 D:0.002 F:0.002 E:0.002
104 ( 1233): G:0.984 Y:0.007 A:0.003 H:0.002 S:0.002 T:0.002
105 ( 1017): Q:0.766 A:0.095 T:0.062 P:0.029 R:0.018 W:0.010
106 ( 1095): G:0.995 R:0.002 P:0.001 T:0.001 Y:0.001 -:0.001
107 ( 1039): T:0.962 Q:0.010 S:0.008 A:0.006 V:0.005 I:0.003
108 ( 1019): T:0.412 L:0.343 S:0.188 M:0.026 G:0.011 P:0.006
109 ( 985): V:0.738 L:0.248 T:0.011 I:0.001 M:0.001 X:0.001
110 ( 984): T:0.972 L:0.008 A:0.007 S:0.005 I:0.003 V:0.002
111 ( 915): V:0.987 A:0.003 I:0.002 L:0.002 C:0.001 F:0.001
112 ( 894): S:0.970 T:0.027 G:0.001 R:0.001 V:0.001
113 ( 831): S:0.767 A:0.211 V:0.012 P:0.004 T:0.004 E:0.002
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