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Publications

[Reviews]                   [Articles]                   [Slides]
Reviews and Book-Chapters
Pub Med PDF Boris Steipe (1999) Evolutionary Approaches to Protein Engineering Current Topics in Microbiology and Immunology: Combinatorial Chemistry in Biology 243:pages...
Pub Med PDF Boris Steipe (1998) Protein Design Concepts Chapter of The Encyclopedia of Computational Chemistry Eds.: P. v. R. Schleyer, N. L. Allinger, T. Clark, J. Gasteiger, P. A. Kollman, H. F. Schaefer III & P. R. Schreiner, John Wiley & Sons, Chichester. pp. 2168-2185
Selected Articles
Pub Med PDF Wiehler J, von Hummel J and Steipe B. (2001) Mutants of Discosoma red fluorescent protein with a GFP-like chromophore FEBS Letters 487:384-389
Pub Med PDF Niggemann, M. and Steipe, B. (2000) Exploring Local and Non-local Interactions for Protein Stability by Structural Motif Engineering J Mol Biol 296: 181-195
Pub Med PDF Ohage, E.C. and Steipe, B. (1999) Intrabody construction and expression I: The critical role of VL domain stability J Mol Biol 291: 1119-1128
Pub Med PDF Ohage, E.C., Wirtz P., Barnikow, J. and Steipe, B. (1999) Intrabody construction and expression II: A synthetic catalytic Fv J Mol Biol 291: 1129-1134
Pub Med PDF Wirtz P. and Steipe, B. (1999) Intrabody construction and expression III: Engineering hyperstable VH domains Protein Science 8: 2245-2250
Pub Med PDF Ohage, E.C., Graml, W., Walter, M.M., Steinbacher, S. and Steipe, B. (1997) beta-turn Propensities as Paradigms for the Analysis of Structural Motifs to Engineer Protein Stability Protein Science 6: 233-241.
Pub Med PDF Korndörfer, I., Steipe, B., Huber, R., Tomschy, A. and Jaenicke, R. (1995) The crystal structure of holo-glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima at 2.5 Å resolution. J Mol Biol 246: 511-521

Structure 1HDG

Pub Med PDF Steinbacher, S., Seckler, R., Miller, S., Steipe, B., Huber,R. and Reinemer, P. (1994) Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer Science 265: 383-386

Structure 1TSP

Pub Med PDF Steipe, B., Schiller, B., Plückthun, A. and Steinbacher, S. (1994) Sequence statistics reliably predict stabilizing mutations in a protein domain. J Mol Biol 240: 188-192.
Pub Med PDF Steipe, B., Plückthun, A. and Huber, R. (1992) Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant. J Mol Biol 225: 739-753

Structure 2IMM and 2IMN

Lecture slides
file Boris Steipe (2002) The Canonical Sequence Approximation: A Rational Route to Intrabodies Lecture slides from CHI 3d. annual "Recombinant Antibodies" conference. Cambridge, Ma, April 24. 2002
[Reviews]                   [Articles]                   [Slides]
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