Lecture 09
(Previous lecture) ... (Next lecture)
Structure Analysis
...
Add:
- Summary points
- Exercises
- Further reading
Lecture Slides
Slide 001
Slide 002
Slide 003
Slide 004
Slide 005
![](/abc/images/5/5c/L09_s005.jpg)
Lecture 09, Slide 005
Rotamers are low-energy conformations of side-chain dihedral angles. Only a small number of rotamer states and combinations are significantly populated in natural proteins. This tremendously simplifies protein structure modelling and prediction problems. However it also guides analysis, e.g. in enzyme active sites the rotamers often exist in strained, rare conformations.
Rotamers are low-energy conformations of side-chain dihedral angles. Only a small number of rotamer states and combinations are significantly populated in natural proteins. This tremendously simplifies protein structure modelling and prediction problems. However it also guides analysis, e.g. in enzyme active sites the rotamers often exist in strained, rare conformations.