Reference alignment for Mbp1 orthologues (MUSCLE)
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Result of MUSCLE alignment of all Mbp1 protein orthologues. Default parameters, CLUSTAL ALN format. Output order of rows kept same as input order, i.e. according to sequence similarity of adjacent rows as represented in the CLUSTAL guide tree. Mbp1-based annotations have been added to the computed alignment by hand.
Annotation Keys:
- * Proposed binding region
- + positively charged residues, oriented for possible DNA binding interactions
- - negatively charged residues, oriented for possible DNA binding interactions
- E beta strand
- H alpha helix
- t beta turn
- x Low complexity region
- C Coiled coil regions predicted by Coils2 program
MUSCLE (3.6) multiple sequence alignment Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ------------------------------------------------------------ Mbp1_ASPTE ------------------------------------------------------------ Mbp1_CRYNE --MEPPSNPIQPPVTPSHHSLLSAISPALSEQTPAPIHTLPPHLRPSIPQPHIAPPRPSS Mbp1_GIBZE ---------------------MSQQSQ--------------------------------- Mbp1_MAGGR MASTVAGNSFVSQQHPGNLHSANLQSQSQGFRRQNSTSSVPSTASFDPPNGSIANTGSQK Mbp1_NEUCR -------------MQPPQLGGASQQSQ--------------------------------- Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ------------------------------------------------------------ Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA ------------------------------------------------------------ Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI -------------------------------------MAAVDF-----------SNVYSA Mbp1_ASPTE -------------------------------------MAGVDF-----------SKIYSA Mbp1_CRYNE VQPTMEEQQRMHHIQQHQQ-QQHFQQQQNDENVFGSVMGAPGHVPGHEAPMSTQPKVYAS Mbp1_GIBZE -----------SGMGNSFR---------------GGYNGDPDN-----------SGIYSA Mbp1_MAGGR HHPMSSQQSQPPASQQSFSMSQTGSQPQPSQSSFRSYSDQNVPQQPQEA-----SPIYTA Mbp1_NEUCR -----------PSSQQSFSMSQS------SQSVYRQYTDPPNRLHNDHAV----PTIYSA Mbp1_CANAL ----------------------------------------MSD-----------SQIYSA Mbp1_DEBHA ---------------------------------------MADN-----------TQIYSA Mbp1_PICST ----------------------------------------MTS-----------TQIYSA Mbp1_CANGL -----------------------------------------MS-----------NQIYSA Mbp1_SACCE -----------------------------------------MS-----------NQIYSA Mbp1_EREGO ----------------------------------MSAGSAVSA-----------TQIYSA Mbp1_KLULA ----------------------------------------MSS-----------NQIYSA Mbp1_YARLI ------------------------------------------------------MSIYKA Mbp1_COPCI ----------------------------------------MPE-----------AQIFKA Mbp1_USTMA ---------------------------------------MSGD-----------KTIFKA Mbp1_SCHPO --------------------------------------MAPRS-----------SAVHVA 1MB1 3D ---------------EEEE Mbp1_ASPFU -----------------MRRRGDDWINATHILKVAGFDKPARTRILEREVQKGTHEKVQG Mbp1_ASPNI TYSSVPVYEFKIGTDSVMRRRSDDWINATHILKVAGFDKPARTRILEREVQKGVHEKVQG Mbp1_ASPTE TYSSVPVYEFKIEGDSVMRRRADDWINATHILKVAGFDKPARTRILEREVQKGVHEKVQG Mbp1_CRYNE VYSGVPVFEAMIRGISVMRRASDSWVNATQILKVAGVHKSARTKILEKEVLNGIHEKIQG Mbp1_GIBZE SYSGVDVYEMEVNNIAVMRRRNDSWLNATQILKVAGVDKGKRTKILEKEIQTGEHEKVQG Mbp1_MAGGR VYSNVEVYEFEVNGVAVMKRIGDSKLNATQILKVAGVEKGKRTKILEKEIQTGEHEKVQG Mbp1_NEUCR TYSGVGVYEMEVNNVAVMRRQKDGWVNATQILKVANIDKGRRTKILEKEIQIGEHEKVQG Mbp1_CANAL TYSNVPAFEFVTSEGPIMRRKKDSWINATHILKIAKFPKAKRTRILEKDVQTGIHEKVQG Mbp1_DEBHA TYSNVPVFEFVTLEGPIMRRKLDSWINATHILKIAKFPKAKRTRILEKDVQTGVHEKVQG Mbp1_PICST TYSNVPVFEYVTSEGPIMRRKSDSWINATHILKIAKFPKAKRTRILEKDVQTGVHEKVQG Mbp1_CANGL KYSGVDVYEFIHPTGSIMKRKNDGWVNATHILKAANFAKAKRTRILEKEVLKEMHEKVQG Mbp1_SACCE RYSGVDVYEFIHSTGSIMKRKKDDWVNATHILKAANFAKAKRTRILEKEVLKETHEKVQG Mbp1_EREGO KYSGVEVYEFLHPTGSIMKRKADDWVNATHILKAAKFAKAKRTRILEKEVIKDTHEKVQG Mbp1_KLULA KYSGVDVYEFIHPTGSIMKRKADNWVNATHILKAAKFPKAKRTRILEKEVITDTHEKVQG Mbp1_YARLI TYSGVPVYEFQCKNVAVMRRKSDGWVNATHILKVAGFDKPQRTRILEKEVQKGVHEKVQG Mbp1_COPCI TYSGIPVYEMMCKGVAVMRRRSDSWLNATQILKVAGFDKPQRTRVLEREVQKGEHEKVQG Mbp1_USTMA TYSGVPVYECIINNVAVMRRRSDDWLNATQILKVVGLDKPQRTRVLEREIQKGIHEKVQG Mbp1_SCHPO VYSGVEVYECFIKGVSVMRRRRDSWLNATQILKVADFDKPQRTRVLERQVQIGAHEKVQG *.* *..:***:*** . . * **.:**.:: ***:** 1MB1 3D Ett-EEEEEEEEt-EEEEEEtt---EEHHHHHHH----HHHHHHHHhhhHHH---EEE-- Annotation **+**-+******+*+*** Mbp1_ASPFU GYGKYQGTWIPLHEGRLLAERNNIIDKLRPIFDYVAG-DH-----TPPPAPKHTSAASSR Mbp1_ASPNI GYGKYQGTWIPLQEGRQLAERNNILDKLLPIFDYVAG-DR-----SPPPAPKHTSAASKP Mbp1_ASPTE GYGKYQGTWIPLPEGRLLAERNNIIDKLRPIFDYVAG-DR-----SPPPAPKHTSAASKP Mbp1_CRYNE GYGKYQGTWVPLDRGRDLAEQYGVGSYLSSVFDFVPS-AS-----VIAALPVIRTGTPDR Mbp1_GIBZE GYGKYQGTWIKFERGLQVCRQYGVEELLRPLLTYDMGQDGGVAGRGDLNTPTKEQAMAAQ Mbp1_MAGGR GYGKYQGTWIKYERALEVCRQYGVEELLRPLLEYNRNPDG-SVSQANLNTPTKEQAMAAQ Mbp1_NEUCR GYGKYQGTWIPFERGLEVCRQYGVEELLSKLLTHNRG-QE--GETGNVDTPTKEQAMAAQ Mbp1_CANAL GYGKYQGTYVPLDLGAAIARNFGVYDVLKPIFEFQYI-EG--QTEVPPPAPKHNHASALN Mbp1_DEBHA GYGKYQGTYVPLDLGADIAKNFGVFDSLRPIFEFTYV-EG--KSETPPPAPKHSHASASN Mbp1_PICST GYGKYQGTYVPLELGRDIAKNFGVFDILKPIFDFKYI-EG--KSETPPPAPKHNHASALN Mbp1_CANGL GFGKYQGTWVPLNIAINLAEKFDVYQDLKPLFDFSEE-NG---DAAPPPAPKHHHASKAS Mbp1_SACCE GFGKYQGTWVPLNIAKQLAEKFSVYDQLKPLFDFTQT-DG---SASPPPAPKHHHASKVD Mbp1_EREGO GFGKYQGTWVPLDIARRLAQKFEVLEELRPLFDFTRR-DG---SESPPQAPKHHHASRAD Mbp1_KLULA GFGKYQGTWIPLELASKLAEKFEVLDELKPLFDFTQQ-EG---SASPPQAPKHHHASRSD Mbp1_YARLI GYGKYQGTWVPLERAREIATLYDVDSHLAPIFNYDDE-DG-----SPPPAPKHRPNLERK Mbp1_COPCI GYGKYQGTWIPLERGMQLAKQYNCEHLLRPIIEFTPA-AK-----SPPLAPKHLVATAGN Mbp1_USTMA GYGKYQGTWIPLDVAIELAERYNIQGLLQPITSYVPSAAD-----SPPPAPKHTISTSNR Mbp1_SCHPO GYGKYQGTWVPFQRGVDLATKYKVDGIMSPILSLDID-EG------KAIAPKKKQTKQKK *:******:: . :. : : * 1MB1 3D --tt--EEEE-HHHHHHHHHH---HHHHtt- Annotation ****** xxxxxxxxxxxxxx Mbp1_ASPFU PR---------------------------------------------ASKKKAVNE---- Mbp1_ASPNI RAPKI--------------------------------------------NKRVVKE---- Mbp1_ASPTE RVSKA------------------------------------------AANRRVANE---- Mbp1_CRYNE SGQQT--------PSGLPGHPNQ-----RVISPFANHGQTTPHMPPPQFIHQGNEQ---- Mbp1_GIBZE RKRLY--------NQSADGRANG-----VSGTFFKNISTTASHAVAAISKARFDSP-G-- Mbp1_MAGGR RKKMY--------NSGADSRNNN-----GGGTFFKNISQTAHSAMTAISKARFDSP---- Mbp1_NEUCR RKRMY--------NASSQENRGI----GSTGTFFKNISSTASTAVAAISKARFDSP---- Mbp1_CANAL VAKRQ--------ASLLKKQKEK---QVQPTLSDTSFGSSTSVPPTTVPKKRGRPK---- Mbp1_DEBHA VAKRQ--------SSVNNSSGDA---NSLNKTSHARKTKSMTSLSGEPPKKRGRPK---- Mbp1_PICST IAKRS--------AVPQQAKKSR---------------TASATLTGEPPKKRGRPK---- Mbp1_CANGL SAKAKKAGRSVSSPAMNDSKTRASTRKANTPSSNDITSDSGAVVNPVVTRRRGRPPNSTL Mbp1_SACCE RKKAI--------RSASTSAIMETKRNNKKAEENQFQSSKILGNPTAAPRKRGRPVGSTR Mbp1_EREGO SARKR--------TTKSPPLPHG--------------------QLDALPKRRGRPPRA-- Mbp1_KLULA STRKK--------ATKSASVPSGKVSEKASSQQQQPVSQQQQQQPGSAPKRRGRPP---- Mbp1_YARLI KRTKV--------TG--------------------------------SPLVRQPSR---- Mbp1_COPCI R-----------------------------------------------PVADGVGE---- Mbp1_USTMA SKKII----------------------------------------PADPGALGRSR---- Mbp1_SCHPO PS---------------------------------------------VRGRRGRKP---- Mbp1_ASPFU -------------------------------------------------------QVFSA Mbp1_ASPNI -------------------------------------------------------DVFSA Mbp1_ASPTE -------------------------------------------------------EVFSA Mbp1_CRYNE ---MMNLPPHPSSLAYPTQPKPYF---------SMPLQHTVGPQYDERHEGMTMTPTMSM Mbp1_GIBZE PRSSRNGASRTASFSRQASMQNGD---DFPSNSQQSFASDYGQQVDSAYSTQQANNSVQM Mbp1_MAGGR GPRGRNGPTRAPSFQRQLSTQSIDDFHGGNSQASNFAENFPPQDVNMAFSAGSEPQPGGL Mbp1_NEUCR APRNRSGPSRAPSFNRQSSMQDVADFPNSQQSLVSTEYATQTQNADSGFGSQTTQPLAGD Mbp1_CANAL ----RATLSATPSLQRSDTT-------PINKSLIDFNANDHSAKSSFIGVVPSFARNDTE Mbp1_DEBHA --RVPMQNNIEPSLQHTDTTPITT--------IPESGPSIGTFNNKKSLGHPTLTRQDTE Mbp1_PICST ---RVPMTAAEPVLKHSDTTP------------INGPMNSINGPLEGSFTHPALSRHDTE Mbp1_CANGL TNKRKLGTGLQRSQSEMAFLKPEI------------------PNDLNSNDIANIQQVNSG Mbp1_SACCE GSRRKLGVNLQRSQSDMGFPRPAI---PNSSISTTQLPSIRSTMGPQSPTLGILEEERHD Mbp1_EREGO RKLSDVANVAGQTQVYSDFPRPSI---PVSSISSNQLPSLQSTLHRSI-------SIEHN Mbp1_KLULA --RNKATVTLQRSQSEMVFPKPSI---------PSSSIQSTKLPSLQPQFGRSATSLSPI Mbp1_YARLI --------------------------------------------------METLTQSTGS Mbp1_COPCI ---------------------------------------------------------ESD Mbp1_USTMA --------------------------------------------------RATSIETESE Mbp1_SCHPO --------------------------------------------------SSLSSSTLHS Mbp1_ASPFU AKPIRNMGPPSFPHEQFEINPGYDDNESI------------------------------- Mbp1_ASPNI VNHHRSMGPPSFHHEHYDVNTGLDEDESI------------------------------- Mbp1_ASPTE VKPHRPMGPPSFTHEQYEMHSGFDEDESI------------------------------- Mbp1_CRYNE DGLAPPADIARMGFPYNPSDIYIDQYGQPHA------TYQASPYGKESGHPSKRQRSDAE Mbp1_GIBZE TEPDPPRKRQRVTMTPAESFNGYGQNVDM------------------------------- Mbp1_MAGGR NGTEPPRKRQRMDMTPANSFGAYANNSQMQ------------------------------ Mbp1_NEUCR GLEQPPRKRQR-VLTPARSFGGQTPGHQPL----------------------------DP Mbp1_CANAL QDALQIMTNNMNLRQEDLASVETDDDEEYH----------NGSRGDGLQNDSFTTKRRKY Mbp1_DEBHA QDALQIMASNMSANQEDLELADKSSDEDMG--------------NRTPIDTQDENIHHED Mbp1_PICST QDALQVMAGNMNIKNEDLELVDSDDDDDVV-------------KKRRNGVNVALSLDSQV Mbp1_CANGL DLLRNEKIQKNIQLKEIDLDDGLSSDVEVQETD----TFQPNHQSSLLGAEGHELRNNDS Mbp1_SACCE SRQQQPQQNNSAQFKEIDLEDGLSSDVEPSQQLQQVFNQNTGFVPQQQSSLIQTQQTESM Mbp1_EREGO RNKAPPQPNHK--YEELDIEDGLSSDIETSI------CTNMVYAGHSNARLPMNTSLLPD Mbp1_KLULA MDVKSPLDQASPQFKELDIEDGLSSDVEPN-------------SIMGTKHEDNTHLMNTK Mbp1_YARLI TMGGTPQHSRQSSLSQLAQSYGLDDSDHV------------------------------- Mbp1_COPCI HDTHSLRGSEDGSMTPSPSEASSSSRTP-------------------------------- Mbp1_USTMA VIGAAPNNVSEGSMSPSPSDISSSSRTP-------------------------------- Mbp1_SCHPO VNEKQPNSSISPTIESSMNKVNLPGAEEQV------------------------------ Annotation xxxxxx xxxxxxxxxxxxxxx Mbp1_ASPFU -----EQATLESSSMAADEEMM----------SMSQHGAYSRKRKREMNEVTAMSISEQE Mbp1_ASPNI -----EQATLESSSMIADEDMI----------SMSQNGPYSSRKRKRGINEVAAMSLSEQ Mbp1_ASPTE -----EQATLESSSMVADEDMM----------TMSQSGAYSRKRKRGNDVPTMSIGEQEH Mbp1_CRYNE GSYIESGAAVQQHVEQDEEADDGLDNDSTASDDARDPPPLPSSMLLPHKPIRPKATPANG Mbp1_GIBZE -----YAAAYPGSPTEPNESFM---YTQS---AIHDRSPIEEG---NGPLEPLPYEMSPD Mbp1_MAGGR ----AYADAFPGSPTEPNDSFI---YTQH---AAANDTLLQQQHDQQTPLQPLPYEQSVE Mbp1_NEUCR FNAGNIANGDSGSPTEPSNSFN---YDQVT--ANDGDASYALG-----PLRPLPYENNAD Mbp1_CANAL PGGMTNGNGLESQADLLTSKELFGVSRTSFEKRANQQHNHYSPLQPYHQPSISLSQENQI Mbp1_DEBHA NDELMTGRELFGTPRNSFERIVQSHNQSHNHLNGSIHDPYGLLQYHHHTSHTHSMRDDAI Mbp1_PICST GDDLLGSKELFGASRGSFERVI---HNHNSNNNGHLQSHDPYSFSQYHQPSVSSQNETDV Mbp1_CANGL PLSPSSSSSLPTSPANLNDSNP---FDQRL--GGGGTSPIISLIPRYSVQSRPQVTDINE Mbp1_SACCE ATSVSSSPSLPTSPGDFADSNP---FEERF--PGGGTSPIISMIPRYPVTSRPQTSDIND Mbp1_EREGO KEEPGLSSSLPSSPSEFSAPMV---FDTQR--MGSATSPLGSMLPRYMAPSRPRTSELDQ Mbp1_KLULA DEPVSSSSSLPSSPSEFSQSVA-------FGSRSNMQTPLQLNGTTSMNMILPKFSSSQN Mbp1_YARLI -------TPSPPTVADDSSDFM----------SDEEVDRQMGNYPRPMMAKPKPIQVRDP Mbp1_COPCI ------------SPIHSPGTYH----------SNGLDGPSSGGRNRYRQSNDRYDEDDDA Mbp1_USTMA -------SPLPADRAHPLH-------------ANHALAGYNGRDANNHAR---------- Mbp1_SCHPO -----SATPLPASPNALLSP------------NDNTIKPVEELGMLEAPLDK-------- Annotation xxxxxxxxxxxxx Mbp1_ASPFU HIL--------YGDQLLDYFMTVGDAP----EATRIPPPQ--PP---ANFQVDRPIDDSG Mbp1_ASPNI EHIL-------YGDQLLDYFMTVGDAP----EATRIPPPQ--PP---ANFQVDRPIDDSG Mbp1_ASPTE IL---------YGDQLLDYFMTVGDAP----EATRVPPPE--PP---VNFQVDRPIDDSG Mbp1_CRYNE R----------IKSRLVQIFNVEG-------QVNLRSVFGLAPD-QLPNFDIDMVIDDQG Mbp1_GIBZE VEN--------KRNVLMGLFLETTGTD----PTKNDTLRGFTP------LELDMPIDLQS Mbp1_MAGGR AEN--------KRSMLMSIFMNDGMSE----QARVDTLRQIHP------RDLDMPIDSQC Mbp1_NEUCR AEA--------KRGMLMGLFMDANGPE----EAIQAALCNVSP------QELDSPIDTQS Mbp1_CANAL YSD--------YFQSLLSYFLDDNNK-----IRSPIPDSLLSPPLPLSKIHIYQTIDSDG Mbp1_DEBHA YAD--------YFTNLLNYFLEDGNNKVRSTQESNIPDKILNPPQPLSKINITQPVDNEG Mbp1_PICST VYSD-------YFSSLLTYFLDDSKI-----RSNNIPEKLLNPPQPISKIQINQPIDNEG Mbp1_CANGL KVND-------YLTKLVDYFISNEMK-----SNKTVPQELLHPP-TQSAPFIDAPIDPEL Mbp1_SACCE KVNK-------YLSKLVDYFISNEMK-----SNKSLPQVLLHPP-PHSAPYIDAPIDPEL Mbp1_EREGO KANE-------YLSKLVDYFINCEVQ-----NNGAVPMELLNPP--HSSPCIDSWIDSEH Mbp1_KLULA GPSDSNQRANEYLSKLVNYFISNDTQ-----NESEIPMELLNPP-LHCSPFIDTWIDPEH Mbp1_YARLI KDL--------YTNDLLNYFVSA--------DDEKIPAFLENPP---AEFDVHRPIDEEG Mbp1_COPCI SRHNGMGDPRSYGDQILEYFIS---------DTNQIPPILITPP---PDFDPNMAIDDDG Mbp1_USTMA -----------YADIILDYFVT---------ENTTVPSLLINPP---PDFNPDMSIDDDE Mbp1_SCHPO -----------YEESLLDFFLHP--------EEGRIPSFLYSPP---PDFQVNSVIDDDG :: * . * :* . Ankyrin 3D --t---- Mbp1_ASPFU NTALHWACAMGDLEIVKDLLRRGA---NIKALSVHEETPLVRAVLFTNNYEKRTFPALLD Mbp1_ASPNI NTALHWACAMGDLEIVKDLLRRGA---DMKALSIHEETPLVRAVLFTNNYEKRTFPALLD Mbp1_ASPTE NTALHWACAMGDLEIVRDLLRRGA---DVKALSVHEETPLVRAVLFTNNYEKRTFPALLE Mbp1_CRYNE HSALHWACALARLSIVQQLIELGA---DIHRGNYAGETPLIRAVLTSNHAEAGSFTDLLH Mbp1_GIBZE HTALHWAATLARMPLLRALIAAGA---SPARVNGSGETALMRACLVTNSQDHNSFPDLLE Mbp1_MAGGR HTALHWAATLSRMTILRRLIEAGA---SPFRVNTSGETPLMRACIVTNSHDNDSMPAILD Mbp1_NEUCR HTALHWAATLSRMPLLRALIHAGA---NPWRVNACGETALMRACTVTNSMENNTFPELLD Mbp1_CANAL NTIFHWACSMGNLNMVEFLLKTFTHSLNPDVRNNNGETPLMFMVKFNNSFQLRNFPLILD Mbp1_DEBHA NTIFHWACSMANNGMIEFLLATFESFLNSDLKNNRGETPLMFLVKFSNSYQLKNFPTLLD Mbp1_PICST NTIFHWACSMANISSIEFLLVTFQ--ISPDIRNNKGETPLMFLVKFVNSFQLRNFPSILQ Mbp1_CANGL HTAFHWACSMGNLPIVEALYETGT---NIRAANANGQTPLMRSAMFHNSYTRRSFPRIFE Mbp1_SACCE HTAFHWACSMGNLPIAEALYEAGT---SIRSTNSQGQTPLMRSSLFHNSYTRRTFPRIFQ Mbp1_EREGO HTAFHWACAMGTLPIVEALLQAGA---SPRALNQAGETPLMRASLVHNSYTKRTYPRIFQ Mbp1_KLULA HTAFHWACAMGTLPIVEALLKAGS---SIRSLNNVGETPLIRSSIFHNCYTKRTYPQIFE Mbp1_YARLI HTALHWACAMGHLRVIELLLKAGS---DVRATNMFGQTPLTRAIMFTNNYDRRTFPKVVD Mbp1_COPCI HTSLHWACAMGRIRIVKLLLSAGA---DIFKVNKAGQTALMRSVMFANNYDVRKFPELYE Mbp1_USTMA HTALHWACAMGRIRVVKLLLSAGA---DIFRVNSNQQTALMRATIFPNSLSS--FT---- Mbp1_SCHPO HTSLHWACSMGHIEMIKLLLRANA---DIGVCNRLSQTPLMRSVIFTNNYDCQTFGQVLE :: :***.::. * . . :*.* * Ankyrin 3D HHHHHHH---HHHHHt-t--t-t-----t----t----HHHHHHHH---------HHHHH Mbp1_ASPFU LLLDTVSFRDWFGATIFHHISETTR-----------------SKGKWKSSRYYCEVLLDK Mbp1_ASPNI LLLDTISFRDWFGATLFHHIAQTTK-----------------SKGKWKSSRYYCEVALEK Mbp1_ASPTE LLLDTVSFRDWFGATLFHHIAETTR-----------------SKGKWKSSRYYCEVLLEK Mbp1_CRYNE LLSPSIRTLDHAYRTVLHHIALVAG-----------------VKGRVPAARTYMASVLEW Mbp1_GIBZE VLGGTIEARDHKGRTVLHHIAVTSA-----------------VKGRNAASRYYLESLLEW Mbp1_MAGGR ILGNTMEVRDSKERTVLHHIALTSA-----------------VSGRSAASRYYLQCLLGW Mbp1_NEUCR LLGCTLDVTDDKGRTVLHHIAVTSA-----------------VKGRHYASRYYLESLLEW Mbp1_CANAL LLKESVLLVDSNGKTVLHHIVDTDS-----------------KHKREKFAQYYLESLLEK Mbp1_DEBHA LLFDSILSIDNYGRTVLHHIALAANNLTSEGSINANTDIHTFKKNKERFARYYMECLFAK Mbp1_PICST MLLESILLVDKSGKTVLHHIALID------------------SEKKFRFARYYMETLFDK Mbp1_CANGL LLSETVFDIDSMGQTVLHHIVK--------------------RKSSTPSAIYYVNVLLSK Mbp1_SACCE LLHETVFDIDSQSQTVIHHIVK--------------------RKSTTPSAVYYLDVVLSK Mbp1_EREGO LLQDTVFDVDSRSQTVVHHIVK--------------------RKSNTPSALYYLDVLLSK Mbp1_KLULA ILKDTVFDLDAKSRNVIHRIVS--------------------RKSHTPSAVYYLDVVLSK Mbp1_YARLI ILQDTLFQVDGQGRTVLHHIAQH-------------------VSKSQSAAKYYVTILLSK Mbp1_COPCI LLHRSTLNIDNSNRTVFHHVVDVAM-----------------SKGKTHAARYYMETILTR Mbp1_USTMA ---DPSLNIDRNDRTVFHHVVDLAL-----------------SRGKPHAARYYMETMINR Mbp1_SCHPO LLQSTIYAVDTNGQSIFHHIVQSTS-----------------TPSKVAAAKYYLDCILEK . * .:.*.: : * : . Ankyrin 3D HHHH-ttHHH-----HHHHHHH----------------------tH--HHHHHHHHH--- Mbp1_ASPFU LHNT------------------------CSQDEIDLL----LSCQDSNGDTAALVAARNG Mbp1_ASPNI LRTT------------------------FSPEEVDLL----LSCQDSVGDTAVLVAARNG Mbp1_ASPTE LRAT------------------------CSAEEIDLL----LSCQDSNGDTAALVAARNG Mbp1_CRYNE VAREQQANNTH----SITNPPNPADRNELAPINLRTL----VDVQDVHGDTALNVAARVG Mbp1_GIBZE VVRQGSAPNSQ--NTQTNGNGPSNSQAASPKMGIARFMTEIVNAQDSVGDTALNIAARIG Mbp1_MAGGR VVRQGAANGGQLNSQTFNGGATVSQSQNATRLDLGRFMSEMLNAQDSAGDTALNIAARIG Mbp1_NEUCR VVRQGSAPSSQ---------ENGIGDRKGRRMGIARFMSEIVNAQDNSGDTALNVAARVG Mbp1_CANAL IVDERQEQGDS--------NGHAMEDDLTKDELVTKF----INHQDSDGNTAFHIAAHNL Mbp1_DEBHA IIEFQEIRDLQ-------EIENKKLSLSDKKELIAKF----INHQDIDGNTAFHIVAYNL Mbp1_PICST IIES------------LEDEEDFAKDPDNKKDLIAKF----INHQDSDGNTAFHICSHNL Mbp1_CANGL IKDI------------------------SPKYRIELL----LNTKDANGDTALHIAARNN Mbp1_SACCE IKDF------------------------SPQYRIELL----LNTQDKNGDTALHIASKNG Mbp1_EREGO LKDF------------------------SPQYRIETL----INAQDCKGSTPLHIAAMNR Mbp1_KLULA IKDF------------------------TPQYRIDVL----INQQDNDGNSPLHYAATNK Mbp1_YARLI ISEN------------------------HSLGVLSQF----MDTQNNEGDTALHILARSG Mbp1_COPCI LADY--------------------------PKELADV----INFQDEDGETALTMAARCR Mbp1_USTMA LADY--------------------------GDQLADI----LNFQDDEGETPLTMAARAR Mbp1_SCHPO LISI------------------------QPFENVVRL----VNLQDSNGDTSLLIAARNG : : . :. :: *.:. : Ankyrin 3D -----------------------------------------t----tt---HHHHHHH-- Mbp1_ASPFU AFRLVNLLLGHCP-RAGDLVNKKGETATSITQRAHLPEQNIPPPPSSITMGIDHT----- Mbp1_ASPNI VFRLVDLLLSRCP-RAGDLVNKRGETASSIMQRAHLAERDIPPPPSSITMGNDHI----- Mbp1_ASPTE AFRLVDILLTHCS-RAGDLVNKKGETAISITQRAHPSERDVPPPPSSVTMGNDHI----- Mbp1_CRYNE NKGLVGLLLDAGA-DK-TRANKLGLRPENFGLEI------EALKISNGEAVMANL----- Mbp1_GIBZE NRSIISQLLEVGA-DP-NIANRVGLRPLDFGIGSENAENKTNGEANVENGVVGTN----- Mbp1_MAGGR NRSIISQLLEVCA-SP-HIANRSGLRPTDFGIGVDSDGAMKTKGDSGGDVENGDV----- Mbp1_NEUCR NRSIISQLLEVGA-DP-TIPNRANLKPLDFGIGIADAETNDDPAQEKTGATTGSG----- Mbp1_CANAL NKKCIKVFINYHRFINFGLRNLVSCTVEDYLASHNYVLRLDPVEHDQSNNSDGDE----- Mbp1_DEBHA NKKCIKVFISYHKYINFHLKNLVSYTVEEYLASHNHVLRLDTSNDDSKEIQDIQEEAYKY Mbp1_PICST NKRCIKVFISYHKYIDFGLRNLVGYTVEDYLASHNYVLRLDQTGEEGEQEETEDL----- Mbp1_CANGL DREFFDILIKNGS-LS-TISNNDGQTPTEIMNQHYQDLHLQAQTNIAGSNTSAYTDSFSS Mbp1_SACCE DVVFFNTLVKMGA-LT-TISNKEGLTANEIMNQQYEQMMIQNGTNQHVNSSNTDLNIHVN Mbp1_EREGO DKKFFQTLVGNGA-LS-TIKNHDGVTADELINNRFVKTIQPTQRGNYHENRASHS----- Mbp1_KLULA DDQFYQLLLQNGA-LT-TVQNNSGMTPNGIISGRYSMDEITKGQRLDDPYEFNKM----- Mbp1_YARLI AKKVSRALMDFNV-KT-DIVNADGRTALDLLEGDRQMQQHPPPAMALHHQPPYQM----- Mbp1_COPCI SKRLVKLLIDHGA-DP-KINNHDGKNAEDYILEDERFRSSPAPSSRVAAMSYRNA----- Mbp1_USTMA SKRLVRLLLEHGA-DP-KIRNKEGKNAEDYIIEDERFRSSPSRTGPAGIELGADG----- Mbp1_SCHPO AMDCVNSLLSYNA-NP-SIPNRQRRTASEYLLEADKKPHSLLQSNSNASHSAFSF----- :: * Ankyrin 3D -HHHHHHHH--t--tt-----t----HHHHHHHH--HHHHH-t--HHH-t----HHHHHH Mbp1_ASPFU ------EGDLTVLETPD------------QTDALPAEASLATSALLAKISAIMAETNKKL Mbp1_ASPNI ------DGEVGAPTSLEP-----------QSVTLHHESSPATAQLLSQIGAIMAEASRKL Mbp1_ASPTE ------DGEVNTSTNPDN-----------QSVAITPDTSSVTATLLSKIGVIIAEANKKL Mbp1_CRYNE -----------------------------------KSEVSKPERKSRDVQKNIATIFESI Mbp1_GIBZE ---------------------------------------QRSRESSDEIVASISHLLSET Mbp1_MAGGR -----------------------------------GGSSQKSNESSNEIVTSITHLLTET Mbp1_NEUCR ---------------------------------------HKSRETSDEVVRSITHLIGES Mbp1_CANAL --------DIMEDYTNEN-----------QSFETQLHNSKMAINLQNTTANLLTEKMTQL Mbp1_DEBHA LNPQFQGNNLTIRNNST------------QSFESQMYFSKMAVNLQNTTANLITEKLTEL Mbp1_PICST ---------LYSQEAVST-----------QSFESQLYYSKVAVNLQNTTSNLITERLTEL Mbp1_CANGL FGGKVKGSKLHSISELDDDKNTQNPENTVTNIVSNLHFSSNAAINLVKNIPAFTDSMKHL Mbp1_SACCE TNNIETKNDVNSMVIMSP-----------VSPSDYITYPSQIATNISRNIPNVVNSMKQM Mbp1_EREGO ----PLNSASAAGGMVPA-----------SLIHTGDMYPSQSATSVSRAIPEVINLMKDM Mbp1_KLULA -------------------------------------YPSQAATRTNRIIPEVINMMKEM Mbp1_YARLI ------------------------------------LHESETAIAAHNLAGTVVHNLQVL Mbp1_COPCI QVAYPPPGAPSTYSFAPA-----------NHDRPPLHYSAAAQKASTRCVNDMASMLDSL Mbp1_USTMA ----------------LP-----------VLPTSSLHTSEAGQRTAGRAVTLMSNLLHSL Mbp1_SCHPO -----------------------------SGISPAIISPSCSSHAFVKAIPSISSKFSQL . Ankyrin 3D H--tHHHHHHHHHH---t------------------tt----HHHHHHH---HHHHHHHH Mbp1_ASPFU AACYGHTKSNEPVSDDVANPEALYEQLEVDRQKIQEQTAALE-----------AKETEGE Mbp1_ASPNI TSSYGAAKPSQKDSDDVANPEALYEQLEQDRQKIRRQYDALA-----------AKEAAEE Mbp1_ASPTE AVSYGSSKPGQQGSDDIANPEALYDQLELDRQKIKQQTAALS-----------AKEAEEE Mbp1_CRYNE SSTFSSEMLAKQ--TKLNATEASVRHATRALADKRQHLHRAQ-----------EKLATMQ Mbp1_GIBZE GSTFQSEMKAKQ--ASLDTLHSTLRTTSTQLGEARRSLEHLS-----------ATLKKQQ Mbp1_MAGGR SANFQEEIKNKQ--KNIDSLHATLRLTTTDVNDLRRKLDEAQ-----------ARVKAQQ Mbp1_NEUCR ASIFQNELKKKQ--ESIDTLHSQLRVTSSQVGDARRTLESLQ-----------EKLKAQQ Mbp1_CANAL AYAIDSELSEKD--EVILTYFKVLSQINQIKLESQRKILSFFKLDHLIEELEQNKDDSQQ Mbp1_DEBHA AYIVDKELSEKD--EKLLMYFKLLKAIGHEKLLSQRAVLQFF-----------KLEYLID Mbp1_PICST AYTIDKELSEKD--ETILTFFKILKSINTEKLVSQKAILSFF-----------KLEYLIE Mbp1_CANGL AEKFDGSYKNHE--ESCRSTEKMLGSIKRTVHSTDNRIREIL-----------ETDADAD Mbp1_SACCE ASIYNDLHEQHD--NEIKSLQKTLKSISKTKIQVSLKTLEVLKESSKDE----NGEAQTN Mbp1_EREGO ADSYQFLYEDRN--QEVQDLVKMLKSMSATVTSLDMKVLEIL-----------EVKDMNN Mbp1_KLULA ANSYQNAYQKRQ--NEVLQMERTVKSMKKTITSVEMKLLEAL-----------NLKETDN Mbp1_YARLI AHAFDAELKEKD--ADVQQVRQMATKMEEDIAATNEAIREYE------------------ Mbp1_COPCI AASFDQELRDKE--RDMAQAQALLTNIQAEILESQRTVLQLR-----------QQAEGLS Mbp1_USTMA ADSYDSEINTAE--KKLTQAHGLLKQIQTEIEDSAKVAEALH--------------HEAQ Mbp1_SCHPO AEEYESQLREKE--EDLIRANRLKQDTLNEISRTYQELTFLQ-----------KNNPTYS Annotation CCCCCCCCCCC--CCCCCCCCCCCC Mbp1_ASPFU -----PVEAQLERYE------RLR--------------STYESLLEQ-------IQQVRL Mbp1_ASPNI -----SSDAQLGRYE------QMR--------------DNYESLLEQ-------IQRARL Mbp1_ASPTE -----PVDTQLARYE------QLR--------------ASYESLLEH-------IQQARL Mbp1_CRYNE -----LFEQRSENVR------RIMDAIAAGTLLTPAEFTGRTQTMHE----KSTGQLPPL Mbp1_GIBZE -----LAKQKVANLS------HARE-------------AEQVRLMQE----QSRASQPNP Mbp1_MAGGR -----LARQKVTNLQ------RAEE-------------RERYRLTQ--------LEQTTG Mbp1_NEUCR -----LAKQKIVNFN------RAC--------------EEEEQILIE-------LEQRHG Mbp1_CANAL QQQQVTDDDDPTSVHGNDLHLDFKRDHILQEEIYRLMNDLTYQELHQ----QDELDKVEH Mbp1_DEBHA DIMADYDQNNSDNLI-----IDTEKDRIIQDEINRLISDLSFQFLQR----KDQLDQVFM Mbp1_PICST DLERVNKETNPQELS-----LDFKRDQIIQDEIHRLINDLTYQFLQK----KEDLYQLHQ Mbp1_CANGL ISSAILAQEKDITEL------KIEA-------------ENHLRKLKN----QFEYLQKQR Mbp1_SACCE DDFEILSRLQEQNTK------KLRKRL-----------IRYKRLIKQ----KLEYRQTVL Mbp1_EREGO --ITYEMDSLKENIA------GLKQKL-----------SEKQKVLVS----LLEKSQRVT Mbp1_KLULA --VDIVLNDRKEKID------ELQRRI-----------ATDKRVLIN----RLEEGQVKL Mbp1_YARLI -----AKHGTAEELE------KLAS-------------EAEERVTTR-------VNQLRK Mbp1_COPCI QAKQRLADLENALQD------KMGRRYRLGFEKWIKDEETREKVIRDAANGDLVLTPATT Mbp1_USTMA -----GVDEERKRVD------SLQLALKHAINKRARD-DLERRWSEG----KQAIKRARL Mbp1_SCHPO QSMENLIREAQETYQ------QLSKRLLIWLEARQI--FDLERSLKP----HTSLSISFP Annotation xxxxxx-----------xxxxxxxxx----xx Mbp1_ASPFU KERLTSMPPPAK-----------ENMMPSSSDQNQLLITYQLARQ--------------L Mbp1_ASPNI KERLASTPVPTQT----------AVIGSSSPEQDRLLTTFQLSRA--------------L Mbp1_ASPTE KERVASMPIPT------------KEQAESSKDTSQLTTVFQLAQK--------------L Mbp1_CRYNE AFRHVPGLALDASSQ--------SQLNGAPPSTPLSVEDQEDIALPERDDP--------E Mbp1_GIBZE SSSWETELS--------------AMLEAADDTSDGEFGGEGLLPS--------------A Mbp1_MAGGR RRDIASANGWEAESN--------TLLATINATTNGEPDADAKLPS--------------S Mbp1_NEUCR RLDVASANAWEMELESA------LEIVKTQSPKGLDPDSRPSLPS--------------A Mbp1_CANAL SYRMTKERLHEKVLDAS------SFVIDQTHQQGNVHEQLELAKQ--------------L Mbp1_DEBHA KYKAISSAIQNTKVAELAST---LSQHESNSSSTEDETPSEQVRLSIELQTQIVKYKQML Mbp1_PICST KYILVNEKV--------------QLTEEIIKCKKLSQQLYKQQMV--------------V Mbp1_CANGL LLKLTE-----------------YHNGEHNDTDNTLDNKIEICKQ--------------I Mbp1_SACCE LNKLIEDETQ-------------ATTNNTVEKDNNTLERLELAQE--------------L Mbp1_EREGO LRKCVEEEKKAIESV--------IAAPADDATHSSKETLADDLRE--------------L Mbp1_KLULA IRKFVDEET--------------KNVEGKTTDGEESEDIEALLKE--------------L Mbp1_YARLI VFERSQAKGLAML----------VAEEEREISREQTKGEFKTAKE--------------L Mbp1_COPCI SYTVDEDGDSDSGSNGDKNKGKRKAQVQQEEVSDLVELYSNIPTDPEELRKQCEALREEV Mbp1_USTMA QAGLEPGALSTSNATN-------APATGDQKSKDDAKSLIEALPAGTNVKTAIAELRKQL Mbp1_SCHPO SDFLKKEDGLSLNN---------DFKKPACNNVTNSDEYEQLINK--------------L Mbp1_ASPFU CSLQKAR-------------RAAVRDLAQQTADAGVS---------------TKFDVHRR Mbp1_ASPNI CSEQKIR-------------RAAVKELAQQRADAGVS---------------TKFDVHRK Mbp1_ASPTE CAAQKAR-------------RAAVKELAQQTADAGVS---------------TKFDVHRK Mbp1_CRYNE CLVKLRR-------------MALWEDRIAEVLEDKIR--------AMEGEGVDRAVKYRK Mbp1_GIBZE AVLEARV-------------RAVKKRCESTRKMVSAL----------KGRSRDTEVKYRR Mbp1_MAGGR ALLRARI-------------EAVKKQTESTRQSVVAL----------KGRSREVEGRYRH Mbp1_NEUCR AVLRARI-------------KALRARSSKTRQAVAAL----------QAQSKEKELKYRR Mbp1_CANAL QVEIIKR-------------KKLVDEISKLTKNVPLPENPNAKTIIDTYPSTDKLYKYCK Mbp1_DEBHA HKLHQQHLQVPLSSLNDNTDTKENKENIKEESQTNDTAEPAPHSVIAKYPKDDKLHKYCK Mbp1_PICST PIPQTSI-------------DKENNSTPTGSSSNSIV---------AKYPHDNLLSKYCH Mbp1_CANGL SVLQIER-------------KRKISELISHYEDS------------------RKIHKYRR Mbp1_SACCE TMLQLQR-------------KNKLSSLVKKFEDN------------------AKIHKYRR Mbp1_EREGO TVLQLRR-------------KHKINRLIELLCGN------------------SKIHKFRK Mbp1_KLULA VLIQLKR-------------KRKLNQIIDVITDN------------------SKVYKYRK Mbp1_YARLI TDLQHGR-------------KDLVDDVVELFANAGVG---------------EKMNEYRR Mbp1_COPCI SQSRKRR-------------KAMFDELVTFQAEAGTS---------------GRMSDYRR Mbp1_USTMA SQVQANK-------------TELVDKFVARAREQGTG---------------RTMAAYRR Mbp1_SCHPO TSLQASR-------------KKDTLYIRKLYEELGID---------------DTVNSYRR . . Mbp1_ASPFU LVALAT-GLKEEELD-PMAAELAETLEFDRMNGRGPG----------------------- Mbp1_ASPNI LVALAT-GLKEEELD-PMAAELAETLEFDRMNGKGVG----------------------- Mbp1_ASPTE LVALAT-GLKEEELD-PMAAELAEALEFDRMNGKGNG----------------------- Mbp1_CRYNE LVSVCA-KVPVDKVD-SMLDGLVAAVESEGQGLDFSR----------------------- Mbp1_GIBZE VVALCT-GVQEDEVD-AVIDGLLKAVESEQEELEINR----------------------- Mbp1_MAGGR LVALAT-KCRDEDVD-STMEGLLKAVESEKGELEIGR----------------------- Mbp1_NEUCR LVSLCT-RRPEIEVE-ALLDTLTRAVESEKPELEIAR----------------------- Mbp1_CANAL LISLSC-GIPMDEIE-TSIDAMEESLVKK------------------------------- Mbp1_DEBHA LIALCC-GMNFNDVE-NSIDLIEQSLSKSAPNMQ-------------------------- Mbp1_PICST LIAQCC-GMDFDDVE-GSIDEIEQSLLKSNVK---------------------------- Mbp1_CANGL MISEGT-EMKTEEVD-GCLDIILQTLINNSS----------------------------- Mbp1_SACCE IIREGT-EMNIEEVD-SSLDVILQTLIANNNKNKGAE----------------------- Mbp1_EREGO MISQGT-DMDISEVD-NFLDVIFQQLNEDEENTNNGG----------------------- Mbp1_KLULA MISQGT-DIDVSDVD-ECLDVIYQTLSKEG------------------------------ Mbp1_YARLI LVAMSC-GVKVEDID-GLLDGIEKALLEGER----------------------------- Mbp1_COPCI LIAAGCGGLEPLEID-SVLGMLLETLEAEDPSSTSAT----------------------- Mbp1_USTMA LIAAGCGGIAPDEVD-AVVGVLCELLQESHTGARAGAGGERDDRARDVAMMLKAFPVYSR Mbp1_SCHPO LIAMSC-GINPEDLSLEILDAVEEALTREK------------------------------ :: .:. : : Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ------------------------------------------------------------ Mbp1_ASPTE ------------------------------------------------------------ Mbp1_CRYNE ------------------------------------------------------------ Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR ------------------------------------------------------------ Mbp1_NEUCR ------------------------------------------------------------ Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ------------------------------------------------------------ Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA CIVMNRQLAVTRYPCCRLLFYSLPCRTNMISGLWMQSDSVAAVLARSNAVLRISPCPKCA Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ------------------------------------------------------------ Mbp1_ASPTE ------------------------------------------------------------ Mbp1_CRYNE ------------------------------------------------------------ Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR ------------------------------------------------------------ Mbp1_NEUCR ------------------------------------------------------------ Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ------------------------------------------------------------ Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA RMSKLQAHLYEASAARLCGGKMLRRTLALFSEAARSSSSSSASAAASSSASILTSHLSKA Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ------------------------------------------------------------ Mbp1_ASPTE ------------------------------------------------------------ Mbp1_CRYNE ------------------------------------------------------------ Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR ------------------------------------------------------------ Mbp1_NEUCR ------------------------------------------------------------ Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ------------------------------------------------------------ Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA HLPPSLARSAKPHKNLYQMLSTLPKDGVGARVRQRRWAAKGLDVSHDVDLKAHLAKLHHT Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU -GESPEPVQKRLPSQREPSSLPFSGPPVSVDA---------------------------- Mbp1_ASPNI -------PESPEADHKDSASLPFPGPVVSVDA---------------------------- Mbp1_ASPTE -------AESPDLEHKDSASFPFPEPTISVDA---------------------------- Mbp1_CRYNE -------------------ASNFVNRIKATKS---------------------------- Mbp1_GIBZE -------------------VRRFLGGVEGVQ----------------------------- Mbp1_MAGGR -------------------VRRFLGGVEGVIG---------------------------- Mbp1_NEUCR -------------------VRRFLGGVEGVVH---------------------------- Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE -------------------QIITISNANSHA----------------------------- Mbp1_EREGO -------------------HTNYNGHVSCAILDTVEGYGIENIENKRGTSQNDGPAK--- Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ----------------------WSGSKGQQTG---------------------------- Mbp1_USTMA GATKTNKDEGHLCYWEITKVRLKDGGNHGKAWGRFVWRERNAGVVKQGQAQAKLTKVCLS Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU ------------------------------- Mbp1_ASPNI ------------------------------- Mbp1_ASPTE ------------------------------- Mbp1_CRYNE ------------------------------- Mbp1_GIBZE ------------------------------- Mbp1_MAGGR ------------------------------- Mbp1_NEUCR ------------------------------- Mbp1_CANAL ------------------------------- Mbp1_DEBHA ------------------------------- Mbp1_PICST ------------------------------- Mbp1_CANGL ------------------------------- Mbp1_SACCE ------------------------------- Mbp1_EREGO ------------------------------- Mbp1_KLULA ------------------------------- Mbp1_YARLI ------------------------------- Mbp1_COPCI ------------------------------- Mbp1_USTMA MVVAHPGKPITKAESGERIPGALKYCWDLAH Mbp1_SCHPO -------------------------------