CSB modelling methods
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Modelling Methods in Computational Biology
This page is a placeholder, or under current development; it is here principally to establish the logical framework of the site. The material on this page is correct, but incomplete.
Intuitively we might think of pathway-, network-, and systems modelling simply as ever more sophisticated systems of coupled differential equations. That is the way it has been done for pathway modelling in biochemistry for decades. However, on a cellular level, matters are more difficult: we simply don't have the precise concentrations and rates available that we would need to populate such models. Important alternative (or complementary) approaches focus on the constraints that are inherent to the real world, such as mass- and energy- balance, or push the boundaries of simpler descriptions, down to purely topological approaches that can be populated in principle from interaction networks.
