Difference between revisions of "Bioinformatics Main Page"

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<small>'''This is our main tool to coordinate information, activities and projects in University of Toronto's bioinformatics course BCH441'''. If you are not one of our students, you can still browse this site, however only users with a login account can edit or contribute or edit material. If you are here because you are interested in general aspects of bioinformatics or computational biology, you may want to review the [http://en.wikipedia.org/wiki/Bioinformatics Wikipedia article on bioinformatics], or visit [http://www.openwetware.org/wiki/Wikiomics Wikiomics]. Contact boris.steipe(at)utoronto.ca with any questions you may have.</small>
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<small>'''These wiki pages are provided to coordinate information, activities and projects in the introductory bioinformatics course taught by Boris Steipe at the University of Toronto'''. If you are not one of my students, you can still browse this site, however only users with a login account can edit or contribute or edit material. If you are here because you are interested in general aspects of bioinformatics or computational biology, you may want to review the [http://en.wikipedia.org/wiki/Bioinformatics Wikipedia article on bioinformatics], or visit [http://www.openwetware.org/wiki/Wikiomics Wikiomics]. Contact boris.steipe(at)utoronto.ca with any questions you may have.</small>
  
 
== The Course ==
 
== The Course ==
  
<div style="padding: 5px; background: #E7C0F0;  border:solid 1px #AAAAAA;">
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BCH441H1F is the undergraduate course code and BCH1441H1F is the corresponding cross-listed course code for graduate students.
I am in the process of repairing the original course Wiki and many of the pages are still arbitrarily outdated. Please don't use pages other than those that are linked directly from here.
 
<br>
 
<span style="font-size:80%;">Contact Boris Steipe for all matters of urgency. November 11. 2011</span>
 
</div>
 
  
 
===Organization===
 
===Organization===
 
;Dates
 
;Dates
 +
 +
The course will be next held in the Fall Term - September to December 2012.
  
 
:Lectures: Monday, 13:00 to 14:00 and Thursday, 12:00 to 13:00  
 
:Lectures: Monday, 13:00 to 14:00 and Thursday, 12:00 to 13:00  
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</table>
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<table cellpadding="5">
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<tr class="sh">
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<td><b>Activity</b></td>
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<td><b>Weight</b><br><small>(Undergraduates)</small></td>
 +
<td><b>Weight</b><br><small>(Graduates)</small></td>
 +
</tr>
 +
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<tr class="sp"><td colspan="3" style="height: 5px;"></td></tr>
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<tr class="s2">
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<td>[[Quizzes|'''9 In-class quizzes''']]</td>
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<td>35 marks <small>(9 x 6)</small></td>
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<td>25 marks <small>(9 x 5)</small></td>
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</tr>
 +
 +
<tr class="s1">
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<td>[[Open project|'''Open project''']]</td>
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<td>18 marks</td>
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<td>18 marks</td>
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</tr>
 +
 +
<tr class="s2">
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<td>[[Participation|'''"Classroom" participation''']]</td>
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<td>8 marks</td>
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<td>8 marks</td>
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</tr>
 +
 +
<tr class="s1">
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<td>[[Graduate project|'''Graduate project''']]</td>
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<td>&nbsp;</td>
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<td>9 marks</td>
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</tr>
 +
 +
<tr class="s2">
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<td>[[Exam questions|'''Final exam''']]</td>
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<td>20 marks</td>
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<td>20 marks</td>
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</tr>
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<tr class="sp"><td colspan="3" style="height: 5px;"></td></tr>
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<tr class="s1">
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<td>'''Total'''</td>
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<td>100 marks</td>
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<td>100 marks</td>
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</tr>
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</table>
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== Assignments ==
 
== Assignments ==
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 +
 +
  
 
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== Temporary links for material ==
 
== Temporary links for material ==
  
===Lecture slides===
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===Lecture slides 2012===
 +
 
 +
''None yet.''
 +
 
 +
===Lecture slides 2011===
 +
 
 
*[http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/01-Introduction.pdf 01 - Introduction to the course <small>(pdf, 6.1 MB)</small>]
 
*[http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/01-Introduction.pdf 01 - Introduction to the course <small>(pdf, 6.1 MB)</small>]
 
*[http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/02-SequenceData.pdf 02 - Sequence Data <small>(pdf, 4.6 MB)</small>]
 
*[http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/02-SequenceData.pdf 02 - Sequence Data <small>(pdf, 4.6 MB)</small>]
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* [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/20-PredictingProteinStructure_II.pdf 20 - Structure Prediction II: ''ab initio'' Prediction  <small>(pdf, 10.0 MB)</small>]
 
* [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/20-PredictingProteinStructure_II.pdf 20 - Structure Prediction II: ''ab initio'' Prediction  <small>(pdf, 10.0 MB)</small>]
 
* [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/22-Outlook-ComputationalSystemsBiology.pdf 22 - Outlook: Computational Systems Biology <small>(pdf, 2.4 MB)</small>]
 
* [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/22-Outlook-ComputationalSystemsBiology.pdf 22 - Outlook: Computational Systems Biology <small>(pdf, 2.4 MB)</small>]
 
===Lecture recordings===
 
*Thursday, 15. September 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/02-SequenceData_2011.mp4 Lecture 02 (Sequence data) <small>(mp4, 16.4 MB)</small>]
 
*Monday, 19. September 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/03-Structure-Data_2011.mp4  Lecture 03 (Sequence data ''cont.''; Structure Data) <small>(mp4, 17.2 MB)</small>]
 
*Thursday, 22. September 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/04-StructureData-SequenceAnalysis_I_2011.mp4  Lecture 04 (Structure data ''cont.''; Sequence Analysis I) <small>(mp4, 16.9 MB)</small>]
 
*Monday, 26. September 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/05-SequenceAnalysis_I-II_2011.mp4  Lecture 05 Sequence Analysis I ''cont.'' & II <small>(mp4, 15.3 MB)</small>]
 
*Thursday, 29. September 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/06-SequenceAnalysis_II-StructureAnalysis_2011.mp4  Lecture 06 Sequence Analysis II ''cont.'' & Analysis of structure <small>(mp4, 15.6 MB)</small>]
 
*Monday, 3. October 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-10-03_Topic-06b.mp4  Analysis of Structure (cont.) <small>(mp4, 18.3 MB)</small>]
 
*Thursday, 6. October 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-10-06_Topic-07.mp4  Lecture 07 Protein Structural Domains  <small>(mp4, 16.3 MB)</small>]
 
*Thursday, 13. October 2011: (Parkinson)
 
*Monday, 17. October 2011:  (Parkinson)
 
*Thursday, 20. October 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-10-20_Topic-10.mp4  Lecture 10 Homology I: Principles <small>(mp4, 19.4 MB)</small>]
 
 
*Monday, 24. October 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-10-24_Topic-11.mp4  Lecture 11 Homology II: Optimal Sequence Alignment <small>(mp4, 12.4 MB)</small>]
 
*Thursday, 27. October 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-10-27_Topic-12.mp4  Lecture 12 Homology III: BLAST <small>(mp4, 16.8 MB)</small>]
 
*Monday, 31. October 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-10-31_Topic-13.mp4  Lecture 13 Homology IV: Multiple Sequence Alignment <small>(mp4, 22.7 MB)</small>]
 
*Thursday, 3. November 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-11-04_Topic-14.mp4  Lecture 14 Predicting Protein Structure I: Homology Modeling <small>(mp4, 18.7 MB)</small>]
 
*Thursday, 10. November 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-11-10_Topic-15.mp4  Lecture 15 Phylogenetic Analysis I: Principles <small>(mp4, 16.7 MB)</small>]
 
*Monday, 14. November 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-11-14_Topic-16.mp4  Lecture 16 Phylogenetic Analysis II <small>(mp4, 18.5 MB)</small>]
 
*Thursday, 17. November 2011: Lecture 17 Comparative Genomics (Parkinson)
 
*Monday, 21. November 2011: Lecture 18 Computational Systems Biology (Parkinson)
 
*Thursday, 24. November 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-11-24_Topic-19.mp4  Lecture 19 Exploratory Data Analysis <small>(mp4, 20.0 MB)</small>]
 
  
  
*Monday, 28. November 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-11-28_Topic-20a.mp4 Lecture 20 Protein structure prediction II: ''ab initio'' <small>(mp4, 15.5 MB)</small>]
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A selection of [[Bioinformatics lecture recordings 2011|Lecture recordings of the 2011 course]] is available.
*Thursday, 1. December 2011: [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/2011-12-01_Topic-20b.mp4 Lecture 20 ''cont.'' <small>(mp4, 13.2 MB)</small>]
 
*Monday, 6. December 2011: Outlook: Computational Systems Biology
 
  
  
 +
=== Add this material ===* Quantitative evolution: signals of recent change and selective pressure
  
  

Revision as of 20:52, 29 December 2011

BCH441 - Bioinformatics

Welcome to the BCH441 Course Wiki.

These wiki pages are provided to coordinate information, activities and projects in the introductory bioinformatics course taught by Boris Steipe at the University of Toronto. If you are not one of my students, you can still browse this site, however only users with a login account can edit or contribute or edit material. If you are here because you are interested in general aspects of bioinformatics or computational biology, you may want to review the Wikipedia article on bioinformatics, or visit Wikiomics. Contact boris.steipe(at)utoronto.ca with any questions you may have.

The Course

BCH441H1F is the undergraduate course code and BCH1441H1F is the corresponding cross-listed course code for graduate students.

Organization

Dates

The course will be next held in the Fall Term - September to December 2012.

Lectures: Monday, 13:00 to 14:00 and Thursday, 12:00 to 13:00
Tutorial sessions: Mondays, 12:00 to 13:00 for in-class quizzes, quiz debriefings, exam preparation and other activities, as the need arises.
Location
MSB 2173 (Medical Sciences Building)
General

See the Course Web page for general information.

We are recommending Understanding Bioinformatics, Zvelebil & Baum, Garland 2008 as a background textbook for the course. (buy used at AbeBooks)

This is an electronic submission only course; but if you must print material, you might consider printing double-sided. Learn how, at the Print-Double-Sided Student Initiative.


Grading and Activities

Activity Weight
(Undergraduates)
Weight
(Graduates)
5 Assignments 15 marks (5 x 3) 10 marks (5 x 2)
5 In-class quizzes 35 marks (5 x 7) 25 marks (5 x 5)
Open project 7 marks 5 marks
"Classroom" participation 3 marks 3 marks
Graduate project   17 marks
Final exam 40 marks 40 marks
Total 100 marks 100 marks


Activity Weight
(Undergraduates)
Weight
(Graduates)
9 In-class quizzes 35 marks (9 x 6) 25 marks (9 x 5)
Open project 18 marks 18 marks
"Classroom" participation 8 marks 8 marks
Graduate project   9 marks
Final exam 20 marks 20 marks
Total 100 marks 100 marks



A note on marking

It is not my policy to adjust marks towards a target mean and variance (i.e. there will be no "belling" of grades). I feel strongly that such "normalization" detracts from a collaborative and mutually supportive learning environment. If your classmate gets a great mark because you helped him with a difficult concept, this should never have the effect that it brings down your mark through class average adjustments. Collaborate as much as possible, it is a great way to learn. However I may adjust marks is if we phrase questions ambiguously on quizzes or if I decide that the final exam was too long.

Assignments

Assignment 5 has been posted.
Due Monday, Dec. 5.

Temporary links for material

Lecture slides 2012

None yet.

Lecture slides 2011


A selection of Lecture recordings of the 2011 course is available.


=== Add this material ===* Quantitative evolution: signals of recent change and selective pressure




 

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