Difference between revisions of "Lecture 01"

Revision as of 21:03, 11 September 2007

Update Warning! This page has not been revised yet for the 2007 Fall term. Some of the slides may be reused, but please consider the page as a whole out of date as long as this warning appears here.

(Next lecture)

Organisation and Orientation

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Mission: Analysis must be followed by interpretation, course is hands-on, interactive and goal oriented.
Technology: Google group, Wiki, supporting material on the Web
Contact information
Technical details of course organisation

Lecture Slides

Slide 001

Lecture 01, Slide 001
Bioinformatics is not only required to master the quantitative aspects of the post-genomic era in molecular biology, it is a qualitative change in our approach to biology as well.

Slide 002

Lecture 01, Slide 002
Bioinformatics can be viewed as the science that develops between the two poles of data management and computational modeling of life.

Slide 003

Lecture 01, Slide 003
From its beginning, it was recognized that molecular biology is an information science, just as much as a molecular science. The abstractions and models that focus on the essence of this information, rather than on the details of its representation, have proven to be remarkably powerful in explaining the basic features of life, such as inheritance, self-organization and the process of evolution.

Slide 004

Lecture 01, Slide 004
The promises of genome analysis include harnessing the power of self assembly towards a bio-nanotechnologic revolution: growth, rather than manufacturing. This includes the vision of regenerative molecular medicine, essentially relegating disease to the dark past ages of ignorance. But while the information for a complete specification of life is undoubtedly present in the genome, life realizes itself in complex interactions between context-dependent components. This makes life essentially unpredictable, at least to our current approaches. The sheer volume of data is a comparatively minor obstacle.

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Lecture 01, Slide 005

Slide 006

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Slide 007

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Slide 008

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-[http://www.ncbi.nlm.nih.gov]
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