Difference between revisions of "BIN-GENOME-Genome Sequencing"
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== Abstract == | == Abstract == | ||
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A basic introduction to "Next Generation Sequencing" concepts and technologies. | A basic introduction to "Next Generation Sequencing" concepts and technologies. | ||
<section end=abstract /> | <section end=abstract /> | ||
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== This unit ... == | == This unit ... == | ||
=== Prerequisites === | === Prerequisites === | ||
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You need the following preparation before beginning this unit. If you are not familiar with this material from courses you took previously, you need to prepare yourself from other information sources: | You need the following preparation before beginning this unit. If you are not familiar with this material from courses you took previously, you need to prepare yourself from other information sources: | ||
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*<b>Biomolecules</b>: The molecules of life; nucleic acids and amino acids; the genetic code; protein folding; post-translational modifications and protein biochemistry; membrane proteins; biological function. | *<b>Biomolecules</b>: The molecules of life; nucleic acids and amino acids; the genetic code; protein folding; post-translational modifications and protein biochemistry; membrane proteins; biological function. | ||
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You need to complete the following units before beginning this one: | You need to complete the following units before beginning this one: | ||
*[[BIN-Sequence|BIN-Sequence (Sequence)]] | *[[BIN-Sequence|BIN-Sequence (Sequence)]] | ||
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=== Objectives === | === Objectives === | ||
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This unit will ... | This unit will ... | ||
* ... introduce methods and concepts of "Next Generation Sequencing" and genome assembly. | * ... introduce methods and concepts of "Next Generation Sequencing" and genome assembly. | ||
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=== Outcomes === | === Outcomes === | ||
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After working through this unit you ... | After working through this unit you ... | ||
* ... are familar with the basic methods and concepts of "Next Generation Sequencing" and genome assembly. | * ... are familar with the basic methods and concepts of "Next Generation Sequencing" and genome assembly. | ||
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=== Deliverables === | === Deliverables === | ||
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*<b>Time management</b>: Before you begin, estimate how long it will take you to complete this unit. Then, record in your course journal: the number of hours you estimated, the number of hours you worked on the unit, and the amount of time that passed between start and completion of this unit. | *<b>Time management</b>: Before you begin, estimate how long it will take you to complete this unit. Then, record in your course journal: the number of hours you estimated, the number of hours you worked on the unit, and the amount of time that passed between start and completion of this unit. | ||
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*<b>Journal</b>: Document your progress in your [[FND-Journal|Course Journal]]. Some tasks may ask you to include specific items in your journal. Don't overlook these. | *<b>Journal</b>: Document your progress in your [[FND-Journal|Course Journal]]. Some tasks may ask you to include specific items in your journal. Don't overlook these. | ||
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*<b>Insights</b>: If you find something particularly noteworthy about this unit, make a note in your [[ABC-Insights|'''insights!''' page]]. | *<b>Insights</b>: If you find something particularly noteworthy about this unit, make a note in your [[ABC-Insights|'''insights!''' page]]. | ||
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<div id="BIO"> | <div id="BIO"> | ||
== Contents == | == Contents == | ||
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{{Task|1= | {{Task|1= | ||
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== Notes == | == Notes == | ||
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<references /> | <references /> | ||
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<div id="ABC-unit-framework"> | <div id="ABC-unit-framework"> | ||
== Self-evaluation == | == Self-evaluation == | ||
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=== Question 1=== | === Question 1=== | ||
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{{CC-BY}} | {{CC-BY}} | ||
Revision as of 01:24, 6 January 2018
Genome sequencing
Keywords: Sequencing technologies, highly parallel, single-molecule and single-cell
Contents
Abstract
A basic introduction to "Next Generation Sequencing" concepts and technologies.
This unit ...
Prerequisites
You need the following preparation before beginning this unit. If you are not familiar with this material from courses you took previously, you need to prepare yourself from other information sources:
- Biomolecules: The molecules of life; nucleic acids and amino acids; the genetic code; protein folding; post-translational modifications and protein biochemistry; membrane proteins; biological function.
You need to complete the following units before beginning this one:
Objectives
This unit will ...
- ... introduce methods and concepts of "Next Generation Sequencing" and genome assembly.
Outcomes
After working through this unit you ...
- ... are familar with the basic methods and concepts of "Next Generation Sequencing" and genome assembly.
Deliverables
- Time management: Before you begin, estimate how long it will take you to complete this unit. Then, record in your course journal: the number of hours you estimated, the number of hours you worked on the unit, and the amount of time that passed between start and completion of this unit.
- Journal: Document your progress in your Course Journal. Some tasks may ask you to include specific items in your journal. Don't overlook these.
- Insights: If you find something particularly noteworthy about this unit, make a note in your insights! page.
Contents
Task:
- Read the introductory notes on genome-scale sequencing technologies.
Further reading, links and resources
A very informative and influential blog about the absolutely newest in the field is written by Lior Pachter, Berkley - "Bits of DNA". Check it out, and return frequently. (continuous)
For the newest published developments Nature subjects collection - NGS (continuous)
Notes
Self-evaluation
If in doubt, ask! If anything about this learning unit is not clear to you, do not proceed blindly but ask for clarification. Post your question on the course mailing list: others are likely to have similar problems. Or send an email to your instructor.
About ...
Author:
- Boris Steipe <boris.steipe@utoronto.ca>
Created:
- 2017-08-05
Modified:
- 2017-11-18
Version:
- 1.0
Version history:
- 1.0 First live 2017
- 0.1 First stub
This copyrighted material is licensed under a Creative Commons Attribution 4.0 International License. Follow the link to learn more.
