Difference between revisions of "WWW GO"
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<section begin=abstract />Ontologies are important tools to organize and compute with non-standardized information, such as gene annotations. The Gene Ontology project ('''GO''') constructs ontologies for gene and gene product attributes across numerous species. Three major ontologies are being developed: '''molecular process''', '''biological function''' and '''cellular location'''. Each includes terms, their definition, and their relationships. In addition, genes and gene products are being been annotated with their GO terms and the type of evidence that underlies the annotation. A number of tools such as the AmiGO browser are available to analyse relationships, construct ontologies and curate annotations. Data can be freely downloaded in formats that are convenient for computation.<section end=abstract /> | <section begin=abstract />Ontologies are important tools to organize and compute with non-standardized information, such as gene annotations. The Gene Ontology project ('''GO''') constructs ontologies for gene and gene product attributes across numerous species. Three major ontologies are being developed: '''molecular process''', '''biological function''' and '''cellular location'''. Each includes terms, their definition, and their relationships. In addition, genes and gene products are being been annotated with their GO terms and the type of evidence that underlies the annotation. A number of tools such as the AmiGO browser are available to analyse relationships, construct ontologies and curate annotations. Data can be freely downloaded in formats that are convenient for computation.<section end=abstract /> | ||
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Latest revision as of 16:59, 28 January 2012
GO: the Gene Ontology project |
URL
Abstract
Ontologies are important tools to organize and compute with non-standardized information, such as gene annotations. The Gene Ontology project (GO) constructs ontologies for gene and gene product attributes across numerous species. Three major ontologies are being developed: molecular process, biological function and cellular location. Each includes terms, their definition, and their relationships. In addition, genes and gene products are being been annotated with their GO terms and the type of evidence that underlies the annotation. A number of tools such as the AmiGO browser are available to analyse relationships, construct ontologies and curate annotations. Data can be freely downloaded in formats that are convenient for computation.
Reference
| Gene Ontology Consortium (2012) The Gene Ontology: enhancements for 2011. Nucleic Acids Res 40:D559-64. (pmid: 22102568) |
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[ PubMed ] [ DOI ] The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies. The number of GO annotations of gene products has increased due to curation efforts among GO Consortium (GOC) groups, including focused literature-based annotation and ortholog-based functional inference. The GO ontologies continue to expand and improve as a result of targeted ontology development, including the introduction of computable logical definitions and development of new tools for the streamlined addition of terms to the ontology. The GOC continues to support its user community through the use of e-mail lists, social media and web-based resources. |
