Difference between revisions of "Reference alignment for Mbp1 orthologues (T-COFFEE)"
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− | + | <div id="BIO"> | |
− | + | <div class="b1"> | |
− | + | Mbp1 orthologues - T-COFFEE alignment | |
− | + | </div> | |
− | + | ||
− | + | ||
− | + | <section begin=contents_summary /> | |
− | + | A multiple sequence alignment for orthologues (by RBM) to ''saccharomyces cerevisiae'' Mbp1 - computed with T-COFFEE. | |
− | + | <section end=contents_summary /> | |
− | + | ||
− | + | ||
− | + | __TOC__ | |
− | + | ||
− | + | ||
+ | ;For a score-colored alignment, see: http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/T-coffee_scores.html . | ||
+ | |||
+ | |||
+ | |||
+ | | ||
+ | ==Methods== | ||
+ | Result of T-COFFEE alignment of all Mbp1 protein orthologues. Default parameters. Output order of rows kept same as input order, i.e. according to sequence similarity of adjacent rows as represented in the CLUSTAL guide tree. Click [http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/T-coffee_scores.html '''here'''] to view the score-colored version of this alignment. | ||
+ | |||
+ | |||
+ | Annotation Keys: | ||
+ | |||
+ | * * Proposed binding region | ||
+ | * + positively charged residues, oriented for possible DNA binding interactions | ||
+ | * - negatively charged residues, oriented for possible DNA binding interactions | ||
+ | * E beta strand | ||
+ | * H alpha helix | ||
+ | * t beta turn | ||
+ | * x Low complexity region | ||
+ | * C Coiled coil regions predicted by Coils2 program | ||
+ | |||
+ | |||
+ | | ||
+ | ==Alignment== | ||
+ | |||
+ | CLUSTAL FORMAT for T-COFFEE Version_5.05 http://www.tcoffee.org, CPU=144.32 sec, SCORE=41, Nseq=18, Len=1485 | ||
+ | |||
+ | Mbp1_ASPFU ------------------------------------------------------------ | ||
+ | Mbp1_ASPNI ---------------------MAA------------------------------------ | ||
+ | Mbp1_ASPTE ---------------------MAG------------------------------------ | ||
+ | Mbp1_CRYNE --MEPPSNPIQPPVTPSHHSLLSAISPALSEQTPAPIHTLPPHLRPSIPQPHIAPPRPSS | ||
+ | Mbp1_GIBZE ----------------- | ||
</div> | </div> |
Latest revision as of 18:48, 1 December 2014
Mbp1 orthologues - T-COFFEE alignment
A multiple sequence alignment for orthologues (by RBM) to saccharomyces cerevisiae Mbp1 - computed with T-COFFEE.
Contents
- For a score-colored alignment, see
- http://biochemistry.utoronto.ca/undergraduates/courses/BCH441H/resources/T-coffee_scores.html .
Methods
Result of T-COFFEE alignment of all Mbp1 protein orthologues. Default parameters. Output order of rows kept same as input order, i.e. according to sequence similarity of adjacent rows as represented in the CLUSTAL guide tree. Click here to view the score-colored version of this alignment.
Annotation Keys:
- * Proposed binding region
- + positively charged residues, oriented for possible DNA binding interactions
- - negatively charged residues, oriented for possible DNA binding interactions
- E beta strand
- H alpha helix
- t beta turn
- x Low complexity region
- C Coiled coil regions predicted by Coils2 program
Alignment
CLUSTAL FORMAT for T-COFFEE Version_5.05 http://www.tcoffee.org, CPU=144.32 sec, SCORE=41, Nseq=18, Len=1485 Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ---------------------MAA------------------------------------ Mbp1_ASPTE ---------------------MAG------------------------------------ Mbp1_CRYNE --MEPPSNPIQPPVTPSHHSLLSAISPALSEQTPAPIHTLPPHLRPSIPQPHIAPPRPSS Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR MASTVAGNSFVSQQHPGNLHSANLQSQSQGFRRQNSTSSVPSTASFDPPNGSIANTGSQK Mbp1_NEUCR -------------MQPPQLGGASQQSQ--------------------------------- Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA -----------------------M------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ------------------------------------------------------------ Mbp1_EREGO ------------------MSAGSA------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA -----------------------M------------------------------------ Mbp1_SCHPO ----------------------MA------------------------------------ Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ---------------------------------------------------VDFS-NVYS Mbp1_ASPTE ---------------------------------------------------VDFS-KIYS Mbp1_CRYNE VQPTMEEQQRMHHIQQH-QQQQHFQQQQNDENVFGSVMGAPGHVPGHEAPMSTQP-KVYA Mbp1_GIBZE ----MSQQSQS---------------------GMGNS--FRGGYN--GD--PDNS-GIYS Mbp1_MAGGR HHPMSSQQSQPPASQQSFSMSQTGSQPQPSQSSFRSY--SDQNVP--QQP-QEAS-PIYT Mbp1_NEUCR -----------PSSQQSFSMSQS------SQSVYRQY--TDPPNR--LHN-DHAVPTIYS Mbp1_CANAL ---------------------------------------------------MSDS-QIYS Mbp1_DEBHA ---------------------------------------------------ADNT-QIYS Mbp1_PICST ---------------------------------------------------MTST-QIYS Mbp1_CANGL ----------------------------------------------------MSN-QIYS Mbp1_SACCE ----------------------------------------------------MSN-QIYS Mbp1_EREGO ---------------------------------------------------VSAT-QIYS Mbp1_KLULA ---------------------------------------------------MSSN-QIYS Mbp1_YARLI ------------------------------------------------------M-SIYK Mbp1_COPCI ---------------------------------------------------MPEA-QIFK Mbp1_USTMA ---------------------------------------------------SGDK-TIFK Mbp1_SCHPO ---------------------------------------------------PRSS-AVHV 1MB1 3D ----EEE Mbp1_ASPFU ------------------MRRRGDDWINATHILKVAGFDKPARTRILEREVQKGTHEKVQ Mbp1_ASPNI ATYSSVPVYEFKIGTDSVMRRRSDDWINATHILKVAGFDKPARTRILEREVQKGVHEKVQ Mbp1_ASPTE ATYSSVPVYEFKIEGDSVMRRRADDWINATHILKVAGFDKPARTRILEREVQKGVHEKVQ Mbp1_CRYNE SVYSGVPVFEAMIRGISVMRRASDSWVNATQILKVAGVHKSARTKILEKEVLNGIHEKIQ Mbp1_GIBZE ASYSGVDVYEMEVNNIAVMRRRNDSWLNATQILKVAGVDKGKRTKILEKEIQTGEHEKVQ Mbp1_MAGGR AVYSNVEVYEFEVNGVAVMKRIGDSKLNATQILKVAGVEKGKRTKILEKEIQTGEHEKVQ Mbp1_NEUCR ATYSGVGVYEMEVNNVAVMRRQKDGWVNATQILKVANIDKGRRTKILEKEIQIGEHEKVQ Mbp1_CANAL ATYSNVPAFEFVTSEGPIMRRKKDSWINATHILKIAKFPKAKRTRILEKDVQTGIHEKVQ Mbp1_DEBHA ATYSNVPVFEFVTLEGPIMRRKLDSWINATHILKIAKFPKAKRTRILEKDVQTGVHEKVQ Mbp1_PICST ATYSNVPVFEYVTSEGPIMRRKSDSWINATHILKIAKFPKAKRTRILEKDVQTGVHEKVQ Mbp1_CANGL AKYSGVDVYEFIHPTGSIMKRKNDGWVNATHILKAANFAKAKRTRILEKEVLKEMHEKVQ Mbp1_SACCE ARYSGVDVYEFIHSTGSIMKRKKDDWVNATHILKAANFAKAKRTRILEKEVLKETHEKVQ Mbp1_EREGO AKYSGVEVYEFLHPTGSIMKRKADDWVNATHILKAAKFAKAKRTRILEKEVIKDTHEKVQ Mbp1_KLULA AKYSGVDVYEFIHPTGSIMKRKADNWVNATHILKAAKFPKAKRTRILEKEVITDTHEKVQ Mbp1_YARLI ATYSGVPVYEFQCKNVAVMRRKSDGWVNATHILKVAGFDKPQRTRILEKEVQKGVHEKVQ Mbp1_COPCI ATYSGIPVYEMMCKGVAVMRRRSDSWLNATQILKVAGFDKPQRTRVLEREVQKGEHEKVQ Mbp1_USTMA ATYSGVPVYECIINNVAVMRRRSDDWLNATQILKVVGLDKPQRTRVLEREIQKGIHEKVQ Mbp1_SCHPO AVYSGVEVYECFIKGVSVMRRRRDSWLNATQILKVADFDKPQRTRVLERQVQIGAHEKVQ *:* *. :***:*** . . * **::**::: ***:* 1MB1 3D EEtt-EEEEEEEEt-EEEEEEtt---EEHHHHHHH----HHHHHHHHhhhHHH---EEE- Annotation **+**-+******+*+** Mbp1_ASPFU GGYGKYQGTWIPLHEGRLLAERNNIIDKLRPIFDY--VAG-DH---TPPPAPKHTSAASS Mbp1_ASPNI GGYGKYQGTWIPLQEGRQLAERNNILDKLLPIFDY--VAG-DR---SPPPAPKHTSAASK Mbp1_ASPTE GGYGKYQGTWIPLPEGRLLAERNNIIDKLRPIFDY--VAG-DR---SPPPAPKHTSAASK Mbp1_CRYNE GGYGKYQGTWVPLDRGRDLAEQYGVGSYLSSVFDFVPS---AS---VIAALPVIRTGTPD Mbp1_GIBZE GGYGKYQGTWIKFERGLQVCRQYGVEELLRPLLTYDMGQDGGVAGRGDLNTPTKEQAMAA Mbp1_MAGGR GGYGKYQGTWIKYERALEVCRQYGVEELLRPLLEYNRNPDGSVS-QANLNTPTKEQAMAA Mbp1_NEUCR GGYGKYQGTWIPFERGLEVCRQYGVEELLSKLLTHNRGQEGET---GNVDTPTKEQAMAA Mbp1_CANAL GGYGKYQGTYVPLDLGAAIARNFGVYDVLKPIFEFQYIEGQTE---VPPPAPKHNHASAL Mbp1_DEBHA GGYGKYQGTYVPLDLGADIAKNFGVFDSLRPIFEFTYVEGKSE---TPPPAPKHSHASAS Mbp1_PICST GGYGKYQGTYVPLELGRDIAKNFGVFDILKPIFDFKYIEGKSE---TPPPAPKHNHASAL Mbp1_CANGL GGFGKYQGTWVPLNIAINLAEKFDVYQDLKPLFDFSEENG-DA---APPPAPKHHHASKA Mbp1_SACCE GGFGKYQGTWVPLNIAKQLAEKFSVYDQLKPLFDFTQTDG-SA---SPPPAPKHHHASKV Mbp1_EREGO GGFGKYQGTWVPLDIARRLAQKFEVLEELRPLFDFTRRDG-SE---SPPQAPKHHHASRA Mbp1_KLULA GGFGKYQGTWIPLELASKLAEKFEVLDELKPLFDFTQQEG-SA---SPPQAPKHHHASRS Mbp1_YARLI GGYGKYQGTWVPLERAREIATLYDVDSHLAPIFNYDDEDG------SPPPAPKHRPNLER Mbp1_COPCI GGYGKYQGTWIPLERGMQLAKQYNCEHLLRPIIEFT--PA-AK---SPPLAPKHLVATAG Mbp1_USTMA GGYGKYQGTWIPLDVAIELAERYNIQGLLQPITSYVP-SA-AD---SPPPAPKHTISTSN Mbp1_SCHPO GGYGKYQGTWVPFQRGVDLATKYKVDGIMSPILSLDIDEGKAIA-------PKKKQTKQK **:******:: . :. : : * 1MB1 3D ---tt--EEEE-HHHHHHHHHH---HHHHtt- Annotation ******* xx---xxxxxxxxxxxx Mbp1_ASPFU RPRASK----KKAVN----------------------EQ-----VFSAA----------- Mbp1_ASPNI P-RAPKI--NKRVVK----------------------ED-----VFSAV----------- Mbp1_ASPTE P-RVSKAAANRRVAN----------------------EE-----VFSAV----------- Mbp1_CRYNE R-SGQQTPSGLPGHPNQRVISPFA---------------NHGQTT-PHMPPPQ-FIHQ-- Mbp1_GIBZE Q-R---KRLYNQSA-DGRANGVSGTFFKNISTTASHAVAAISKARFDSPGPRSSRNGASR Mbp1_MAGGR Q-R---KKMYNSGA-DSRNNNGGGTFFKNISQTAHSAMTAISKARFDSPGPRG-RNGPTR Mbp1_NEUCR Q-R---KRMYNASSQENRGIGSTGTFFKNISSTASTAVAAISKARFDSPAPRN-RSGPSR Mbp1_CANAL N-VAKRQASLLKKQK-EKQVQPTLSDTS-----FGSSTS-----VPPTTVPKK-RGRPKR Mbp1_DEBHA N-VAKRQSSVNNSSG-DANSLNKTSHAR-----KTKSMT-----SLSGEPPKK-RGRPKR Mbp1_PICST N-IAKRSAVPQQAKK-SRTASATL----------------------TGEPPKK-RGRPKR Mbp1_CANGL S-SAKAKKAGRSVSSPAMNDSKTRASTRKANTPSSNDITSDSGAVVNPVVTRR-RGRPPN Mbp1_SACCE D-R---KKAIRSASTSAIMETKRNNKKAEENQFQSSKILGNPTA-----APRK-RGRPVG Mbp1_EREGO D-SAR-KRTTKSPPLPHGQL----------------------DA-----LPKR-RGRPPR Mbp1_KLULA D-STR-KKATKSASVPSGKVSEKASSQQ--QQPVSQQQQQQPGS-----APKR-RGRPPR Mbp1_YARLI -KKRTKV----TGSPLVRQPSRMETLTQSTGSTMG--------------------GTPQH Mbp1_COPCI N-R----P----VADGVGEESDHDTHSLRGSED------------------------GSM Mbp1_USTMA R-SKKIIP----ADPGALGRSRRATSIETESEV-------------IGAAPNN-VSEGSM Mbp1_SCHPO KPSVRGR-----------------------------------------------RGRKPS Mbp1_ASPFU ---------------------------------------KPIRN-MGPPSF--------P Mbp1_ASPNI ---------------------------------------NHHRS-MGPPSF--------H Mbp1_ASPTE ---------------------------------------KPHRP-MGPPSF--------T Mbp1_CRYNE -----GNEQMMNLPPHPSSLAYPTQPKPYFSMPLQH----TVGPQYDERHEGMTMTPTMS Mbp1_GIBZE TA-------SFSRQASMQNGD-------------------DFPS-NSQQS---------- Mbp1_MAGGR AP-------SFQRQLSTQSID-------------------DFHGGNSQAS---------- Mbp1_NEUCR AP-------SFNRQSSMQDVA-------------------DFP--NSQQS---------- Mbp1_CANAL ATLS---AT-PSLQRSDTTPINKSLIDFNANDHSAKSSF----I-GVVPSF--------A Mbp1_DEBHA VPMQN--NIEPSLQHTDTTPITTIPES-----GPSIGTFNNKKS-LGHPTL--------T Mbp1_PICST VPMT---AAEPVLKHSDTTPINGPMNS---INGPLEGSF-------THPAL--------S Mbp1_CANGL STLTNKRKLGTGLQRSQSEMAFLKPEIPND---LNSNDIANIQQ-----VNSGDL----L Mbp1_SACCE STRGSRRKLGVNLQRSQSDMGFPRPAIPNS--SISTTQLPSIRSTMGPQSPTLGILEE-E Mbp1_EREGO ARKLSDVANVAGQTQVYSD--FPRPSIPVS--SISSNQLPSLQSTLHRSISI---EHNR- Mbp1_KLULA NKATVTLQR-SQSEMV-----FPKPSIPSS--SIQSTKLPSLQPQFGRSATSLSPIMDV- Mbp1_YARLI SRQSSLSQLAQ------------------------------------------------- Mbp1_COPCI -----------------------------------------------------------T Mbp1_USTMA -----------------------------------------------------------S Mbp1_SCHPO SLSSSTL-------------HSVNEKQPNS--SISPTIESSMNKVN-------------- Mbp1_ASPFU HEQFEI--NPGYDDNESIEQA--TLES--SSMAADEEMMSMSQ-----HGAY-SRKRKRE Mbp1_ASPNI HEHYDV--NTGLDEDESIEQA--TLES--SSMIADEDMISMSQ-----NGPYSSRKRKRG Mbp1_ASPTE HEQYEM--HSGFDEDESIEQA--TLES--SSMVADEDMMTMSQ-----SGAY-SRKRKRG Mbp1_CRYNE MDGLAPPA-DIARMGFPYNPS--DIYI--DQYGQPHATYQAS-PYGKESGHPSKRQRSDA Mbp1_GIBZE -------------FASDYG-Q--QVDS--AYSTQQAN------NSVQMTEPDPPRKRQRV Mbp1_MAGGR ------------NFAENFPPQ--DVNM--AFSAGSEP------QPGGLNGTEPPRKRQRM Mbp1_NEUCR ------------LVSTEYATQ--TQNADSGFGSQTTQ------PLAGDGLEQPPRKRQRV Mbp1_CANAL RNDTEQDALQIMTNNMNLRQE--DLAS--VETDDDEEYHNGSRGDGLQNDSFTTKRRKYP Mbp1_DEBHA RQDTEQDALQIMASNMSANQE--DLEL--ADKSSDEDMGNRTPIDTQDE----------- Mbp1_PICST RHDTEQDALQVMAGNMNIKNE--DLEL--VDSDDDDDVVKKRR----------------- Mbp1_CANGL R------N-EKIQKNIQLKEI--DLDD--GLSSDVEVQ--------ETD----------- Mbp1_SACCE RHDSRQQQ-PQQNNSAQFKEI--DLED--GLSSDVEPSQQLQQVFNQNT----------- Mbp1_EREGO -------NKAPPQPNHKYEEL--DIED--GLSSDIETSICTNMVYAGHS----------- Mbp1_KLULA -------KSPLDQASPQFKEL--DIED--GLSSDVEPN---SIMGTKHE----------- Mbp1_YARLI --------SYGLDDSDHVTPSPPTVADDSSDFMSDEEVDR-------------------- Mbp1_COPCI PSPSEA--SSSSRTPSPIHSP--GTYH--SNGL-DGP----------------------- Mbp1_USTMA PSPSDI--SSSSRTPSPLPAD--------------------------------------- Mbp1_SCHPO ------------------------------------------------------------ Annotation xxx-xxx Mbp1_ASPFU MNE--------------------------------------------------------- Mbp1_ASPNI INE--------------------------------------------------------- Mbp1_ASPTE -ND--------------------------------------------------------- Mbp1_CRYNE EGSYIE-----------------------SGAAVQQHVEQD------EEADDGLDN---- Mbp1_GIBZE T-MTPAESFNGYGQNVD------M------------YAAAYPGSPTEPNESFMYTQSAIH Mbp1_MAGGR D-MTPANSFGAYANNSQ------MQ----------AYADAFPGSPTEPNDSFIYTQHAAA Mbp1_NEUCR --LTPARSFGGQTPGHQPLDPFNAG----------NIANGDSGSPTEPSNSFNYDQVTAN Mbp1_CANAL GGMTNGNGL--ESQADL-LTSKELF------GVSRTSFEKR------AN----------- Mbp1_DEBHA -------NIHHEDNDEL-MTGRELF------GTPRNSFERI------VQSHNQSHN---- Mbp1_PICST NGVNVALSLDSQVGDDL-LGSKELF------GASRGSFERV------IHNHNSNNN---- Mbp1_CANGL -------TFQPNHQSSL-LGAEGHELRNNDSPLSPSSSSSLPTSPANLNDSNPFDQ---- Mbp1_SACCE -------GFVPQQQSSL-IQTQQTE----SMATSVSSSPSLPTSPGDFADSNPFEE---- Mbp1_EREGO -------NARLPMNTSL--------LPDKEEP---GLSSSLPSSPSEFSAPMVFDTQ--- Mbp1_KLULA -------D-----NTHL--------MNTKDEP--VSSSSSLPSSPSEFSQSVAFGSRSNM Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA ------------------------------------------------------------ Mbp1_SCHPO -------------------------LPGAEEQ---VSATPLPASPNALLSPN-------- Annotation xxxxxx-xxxxxxx----xxxxxxxxxxxxxxxx Mbp1_ASPFU -------------------------VTAMSI---SEQEHILYGDQLLDYFMTVGD----A Mbp1_ASPNI -------------------------VAAMSL---SEQEHILYGDQLLDYFMTVGD----A Mbp1_ASPTE -------------------------VPTMSI---GEQEHILYGDQLLDYFMTVGD----A Mbp1_CRYNE -DSTASDDARDPPPLPSSMLLPHKP-----IRPKATPANGRIKSRLVQIFNVEG-----Q Mbp1_GIBZE DR----------------SPIEEGNGPLEPLPYEMSPDVENKRNVLMGLFLETT-----G Mbp1_MAGGR NDT-------------LLQQQHDQQTPLQPLPYEQSVEAENKRSMLMSIFMNDG-----M Mbp1_NEUCR D-----------------GDASYALGPLRPLPYENNADAEAKRGMLMGLFMDAN-----G Mbp1_CANAL ----Q-------QHNHYS-PLQPYHQPSISLSQE-NQIYSDYFQSLLSYFLDDNN----- Mbp1_DEBHA --HLN-----GSIHDPYG-LLQYHHHTSHTHSMRDDAIYADYFTNLLNYFLEDGNNKVRS Mbp1_PICST -GHLQ-------SHDPYS-F-SQYHQPSVSSQNETDVVYSDYFSSLLTYFLDDSK----- Mbp1_CANGL --RLG-----GGGTSPIISLIPRYSVQSRPQVTDINEKVNDYLTKLVDYFISNE-----M Mbp1_SACCE --RFP-----GGGTSPIISMIPRYPVTSRPQTSDINDKVNKYLSKLVDYFISNE-----M Mbp1_EREGO ---RM-----GSATSPLGSMLPRYMAPSRPRTSELDQKANEYLSKLVDYFINCE-----V Mbp1_KLULA QTPLQ-----LNGTTSMNMILPKFS-SSQNGPSDSNQRANEYLSKLVNYFISND-----T Mbp1_YARLI ----------QMGNYP-------RPMMAKPKPIQVRDPKDLYTNDLLNYFVSAD------ Mbp1_COPCI ----S-----SGGRNRYRQSNDRYDEDDDASRHNGMGDPRSYGDQILEYFISD------- Mbp1_USTMA ------------RAHPLHANHALAGYNGRDA-----NNHARYADIILDYFVTE------- Mbp1_SCHPO ----------------------DNTIKPVEELGMLEAPLDKYEESLLDFFLHPE------ :: * Mbp1_ASPFU PEATRIP-----PPQPPANFQVDRPIDDSGNTALHWACAMGDLEIVKDLLRRGA---NIK Mbp1_ASPNI PEATRIP-----PPQPPANFQVDRPIDDSGNTALHWACAMGDLEIVKDLLRRGA---DMK Mbp1_ASPTE PEATRVP-----PPEPPVNFQVDRPIDDSGNTALHWACAMGDLEIVRDLLRRGA---DVK Mbp1_CRYNE VNLRSV---FGLAPDQLPNFDIDMVIDDQGHSALHWACALARLSIVQQLIELGA---DIH Mbp1_GIBZE TDPTKNDTLRG-----FTPLELDMPIDLQSHTALHWAATLARMPLLRALIAAGA---SPA Mbp1_MAGGR SEQARVDTLRQ-----IHPRDLDMPIDSQCHTALHWAATLSRMTILRRLIEAGA---SPF Mbp1_NEUCR PEEAIQAALCN-----VSPQELDSPIDTQSHTALHWAATLSRMPLLRALIHAGA---NPW Mbp1_CANAL KIRSPIPDSLLSPPLPLSKIHIYQTIDSDGNTIFHWACSMGNLNMVEFLLKTFTHSLNPD Mbp1_DEBHA TQESNIPDKILNPPQPLSKINITQPVDNEGNTIFHWACSMANNGMIEFLLATFESFLNSD Mbp1_PICST IRSNNIPEKLLNPPQPISKIQINQPIDNEGNTIFHWACSMANISSIEFLLVTF--QISPD Mbp1_CANGL KSNKTVPQELLHPPTQSAP-FIDAPIDPELHTAFHWACSMGNLPIVEALYETGT---NIR Mbp1_SACCE KSNKSLPQVLLHPPPHSAP-YIDAPIDPELHTAFHWACSMGNLPIAEALYEAGT---SIR Mbp1_EREGO QNNGAVPMELLNPP-HSSP-CIDSWIDSEHHTAFHWACAMGTLPIVEALLQAGA---SPR Mbp1_KLULA QNESEIPMELLNPPLHCSP-FIDTWIDPEHHTAFHWACAMGTLPIVEALLKAGS---SIR Mbp1_YARLI --DEKIPAFLENPP---AEFDVHRPIDEEGHTALHWACAMGHLRVIELLLKAGS---DVR Mbp1_COPCI --TNQIPPILITPP---PDFDPNMAIDDDGHTSLHWACAMGRIRIVKLLLSAGA---DIF Mbp1_USTMA --NTTVPSLLINPP---PDFNPDMSIDDDEHTALHWACAMGRIRVVKLLLSAGA---DIF Mbp1_SCHPO --EGRIPSFLYSPP---PDFQVNSVIDDDGHTSLHWACSMGHIEMIKLLLRANA---DIG :* . :: :***.::. . * . Ankyrin 3D --t----HHHHHHH---HHHHHt-t--t-t-----t- Mbp1_ASPFU ALSVHEETPLVRAVLFTNNYEKRTFPALLDLLLDTVSFRDWFGATIFHHISETT------ Mbp1_ASPNI ALSIHEETPLVRAVLFTNNYEKRTFPALLDLLLDTISFRDWFGATLFHHIAQTT------ Mbp1_ASPTE ALSVHEETPLVRAVLFTNNYEKRTFPALLELLLDTVSFRDWFGATLFHHIAETT------ Mbp1_CRYNE RGNYAGETPLIRAVLTSNHAEAGSFTDLLHLLSPSIRTLDHAYRTVLHHIALVA------ Mbp1_GIBZE RVNGSGETALMRACLVTNSQDHNSFPDLLEVLGGTIEARDHKGRTVLHHIAVTS------ Mbp1_MAGGR RVNTSGETPLMRACIVTNSHDNDSMPAILDILGNTMEVRDSKERTVLHHIALTS------ Mbp1_NEUCR RVNACGETALMRACTVTNSMENNTFPELLDLLGCTLDVTDDKGRTVLHHIAVTS------ Mbp1_CANAL VRNNNGETPLMFMVKFNNSFQLRNFPLILDLLKESVLLVDSNGKTVLHHIVDTD------ Mbp1_DEBHA LKNNRGETPLMFLVKFSNSYQLKNFPTLLDLLFDSILSIDNYGRTVLHHIALAANNLTSE Mbp1_PICST IRNNKGETPLMFLVKFVNSFQLRNFPSILQMLLESILLVDKSGKTVLHHIALID------ Mbp1_CANGL AANANGQTPLMRSAMFHNSYTRRSFPRIFELLSETVFDIDSMGQTVLHHIV--------- Mbp1_SACCE STNSQGQTPLMRSSLFHNSYTRRTFPRIFQLLHETVFDIDSQSQTVIHHIV--------- Mbp1_EREGO ALNQAGETPLMRASLVHNSYTKRTYPRIFQLLQDTVFDVDSRSQTVVHHIV--------- Mbp1_KLULA SLNNVGETPLIRSSIFHNCYTKRTYPQIFEILKDTVFDLDAKSRNVIHRIV--------- Mbp1_YARLI ATNMFGQTPLTRAIMFTNNYDRRTFPKVVDILQDTLFQVDGQGRTVLHHIAQHVS----- Mbp1_COPCI KVNKAGQTALMRSVMFANNYDVRKFPELYELLHRSTLNIDNSNRTVFHHVVDVA------ Mbp1_USTMA RVNSNQQTALMRATIFPNSLSSFTDPSL---------NIDRNDRTVFHHVVDLA------ Mbp1_SCHPO VCNRLSQTPLMRSVIFTNNYDCQTFGQVLELLQSTIYAVDTNGQSIFHHIVQST------ . :*.* * . : * .:.*:: Ankyrin 3D ---t----HHHHHHHH---------HHHHHHHHH-ttHHH-----HHHHHH--------- Mbp1_ASPFU -----------RSKGKWKSSRYYCEVLLDKLHNT-------------------------- Mbp1_ASPNI -----------KSKGKWKSSRYYCEVALEKLRTT-------------------------- Mbp1_ASPTE -----------RSKGKWKSSRYYCEVLLEKLRAT-------------------------- Mbp1_CRYNE -----------GVKGRVPAARTYMASVLEWVAREQQANNTHS----------ITNPPNPA Mbp1_GIBZE -----------AVKGRNAASRYYLESLLEWVVRQGSAPNSQ-NTQTNGNGPSNSQAASP- Mbp1_MAGGR -----------AVSGRSAASRYYLQCLLGWVVRQGAANGGQLNSQTFNGG-ATVSQSQNA Mbp1_NEUCR -----------AVKGRHYASRYYLESLLEWVVRQGSAPSSQE----NGIGDRK------G Mbp1_CANAL -----------SKHKREKFAQYYLESLLEKIVDERQEQGDSN----------GHAME-DD Mbp1_DEBHA GSINANTDIHTFKKNKERFARYYMECLFAKIIEFQEIRDLQE----------IENKKLSL Mbp1_PICST -----------S-EKKFRFARYYMETLFDKIIESLEDEED-------------FAKD-PD Mbp1_CANGL -----------KRKSSTPSAIYYVNVLLSKIKDI-------------------------- Mbp1_SACCE -----------KRKSTTPSAVYYLDVVLSKIKDF-------------------------- Mbp1_EREGO -----------KRKSNTPSALYYLDVLLSKLKDF-------------------------- Mbp1_KLULA -----------SRKSHTPSAVYYLDVVLSKIKDF-------------------------- Mbp1_YARLI --------------KSQSAAKYYVTILLSKISEN-------------------------- Mbp1_COPCI -----------MSKGKTHAARYYMETILTRLADY-------------------------- Mbp1_USTMA -----------LSRGKPHAARYYMETMINRLADY-------------------------- Mbp1_SCHPO -----------STPSKVAAAKYYLDCILEKLISI-------------------------- : * : : Ankyrin 3D -----------H--tH--HHHHHHHHH--------------------------------- Mbp1_ASPFU ----CSQDEIDLLLSCQDSNGDTAALVAARNGAFRLVNLLLGHCPRA-GDLVNKKGETAT Mbp1_ASPNI ----FSPEEVDLLLSCQDSVGDTAVLVAARNGVFRLVDLLLSRCPRA-GDLVNKRGETAS Mbp1_ASPTE ----CSAEEIDLLLSCQDSNGDTAALVAARNGAFRLVDILLTHCSRA-GDLVNKKGETAI Mbp1_CRYNE DRNELAPINLRTLVDVQDVHGDTALNVAARVGNKGLVGLLLDAGADK--TRANKLGLRPE Mbp1_GIBZE -KM-GIARFMTEIVNAQDSVGDTALNIAARIGNRSIISQLLEVGADP--NIANRVGLRPL Mbp1_MAGGR TRL-DLGRFMSEMLNAQDSAGDTALNIAARIGNRSIISQLLEVCASP--HIANRSGLRPT Mbp1_NEUCR RRM-GIARFMSEIVNAQDNSGDTALNVAARVGNRSIISQLLEVGADP--TIPNRANLKPL Mbp1_CANAL ---LTKDELVTKFINHQDSDGNTAFHIAAHNLNKKCIKVFINYHRFINFGLRNLVSCTVE Mbp1_DEBHA ---SDKKELIAKFINHQDIDGNTAFHIVAYNLNKKCIKVFISYHKYINFHLKNLVSYTVE Mbp1_PICST ----NKKDLIAKFINHQDSDGNTAFHICSHNLNKRCIKVFISYHKYIDFGLRNLVGYTVE Mbp1_CANGL ----SPKYRIELLLNTKDANGDTALHIAARNNDREFFDILIKNGSLS--TISNNDGQTPT Mbp1_SACCE ----SPQYRIELLLNTQDKNGDTALHIASKNGDVVFFNTLVKMGALT--TISNKEGLTAN Mbp1_EREGO ----SPQYRIETLINAQDCKGSTPLHIAAMNRDKKFFQTLVGNGALS--TIKNHDGVTAD Mbp1_KLULA ----TPQYRIDVLINQQDNDGNSPLHYAATNKDDQFYQLLLQNGALT--TVQNNSGMTPN Mbp1_YARLI ----HSLGVLSQFMDTQNNEGDTALHILARSGAKKVSRALMDFNVKT--DIVNADGRTAL Mbp1_COPCI ------PKELADVINFQDEDGETALTMAARCRSKRLVKLLIDHGADP--KINNHDGKNAE Mbp1_USTMA ------GDQLADILNFQDDEGETPLTMAARARSKRLVRLLLEHGADP--KIRNKEGKNAE Mbp1_SCHPO ----QPFENVVRLVNLQDSNGDTSLLIAARNGAMDCVNSLLSYNANP--SIPNRQRRTAS : .:. :: *.:. : :: * Ankyrin 3D -------------t----tt---HHHHHHH---HHHHHHHH--t-tt------t----HH Mbp1_ASPFU SITQRAHLPEQNIPP-PPSSITMGIDHTEGDL----------------------TVLETP Mbp1_ASPNI SIMQRAHLAERDIPP-PPSSITMGNDHIDGEV----------------------GAPTSL Mbp1_ASPTE SITQRAHPSERDVPP-PPSSVTMGNDHIDGEV----------------------NTSTNP Mbp1_CRYNE NFGLEIE-ALKISNGEAVMA-----------NLKSEVSKP-------------------- Mbp1_GIBZE DFGIGSEN---AENKTNGEA-------------------------------------NVE Mbp1_MAGGR DFGIGVDSDGAMKTKGDSGG-------------------------------------DVE Mbp1_NEUCR DFGIGIAD---AETNDDPAQ-------------------------------------EKT Mbp1_CANAL DYLASHNYVLRLDPVEHDQSNNSDGDE----DIMED---------------------YTN Mbp1_DEBHA EYLASHNHVLRLDTSNDDSKEIQDIQEEAYKYLNPQFQGNN-------------LTIRNN Mbp1_PICST DYLASHNYVLRLDQT-GEEGEQEETED----LLYSQ---------------------EAV Mbp1_CANGL EIMNQHYQDLHLQAQTNIAGSNTSAYTDSFSSFGGKVKGSKLHSISELDDDKNTQNPENT Mbp1_SACCE EIMNQQYEQMMIQNGTNQHVNSSNTD------LNIHVNTNNIET-------KNDVNSMVI Mbp1_EREGO ELINNRFVKTIQPTQRGNYHENRAS-------------HSPLNS-------ASAAGGMVP Mbp1_KLULA GIISGRYSMDE--ITKG----------------------QRLDD-------PYEF----- Mbp1_YARLI DLLEGDRQMQQH-PPPAMALHHQ------------------------------------- Mbp1_COPCI DYILEDERFRSSPAPSSRVAAMSYRNAQVA------YPPPG------------APSTYSF Mbp1_USTMA DYIIEDERFRSSPSRTGPAGIELGADGLPV------LPT--------------------- Mbp1_SCHPO EYLLEADKKPHSLLQSNSNASHSA-FSFSGIS---------------------------- Ankyrin 3D HHHHHH--HHHHH-t--HHH-t----------HHHHHHH--tHH-------HHHHHHHH- Mbp1_ASPFU D-QTD--ALPAEASLATSALLAKISAIMAETNKKLAACYGHTKSNEPVSDDVANPEALYE Mbp1_ASPNI EPQSV--TLHHESSPATAQLLSQIGAIMAEASRKLTSSYGAAKPSQKDSDDVANPEALYE Mbp1_ASPTE DNQSV--AITPDTSSVTATLLSKIGVIIAEANKKLAVSYGSSKPGQQGSDDIANPEALYD Mbp1_CRYNE -----------------ERKSRDVQKNIATIFESISSTFSSEM--LAKQTKLNATEASVR Mbp1_GIBZE NGVVG-------TNQRSRESSDEIVASISHLLSETGSTFQSEM--KAKQASLDTLHSTLR Mbp1_MAGGR NGDVGG------SSQKSNESSNEIVTSITHLLTETSANFQEEI--KNKQKNIDSLHATLR Mbp1_NEUCR GATTG-------SGHKSRETSDEVVRSITHLIGESASIFQNEL--KKKQESIDTLHSQLR Mbp1_CANAL ENQSF--ETQLHNSKMAINLQNTTANLLTEKMTQLAYAIDSEL--SEKDEVILTYFKVLS Mbp1_DEBHA STQSF--ESQMYFSKMAVNLQNTTANLITEKLTELAYIVDKEL--SEKDEKLLMYFKLLK Mbp1_PICST STQSF--ESQLYYSKVAVNLQNTTSNLITERLTELAYTIDKEL--SEKDETILTFFKILK Mbp1_CANGL VTNIVSN--LHFSSNAAINLVKNIPAF-TDSMKHLAEKFDGSY--KNHEESCRSTEKMLG Mbp1_SACCE MSPVSPSDYITYPSQIATNISRNIPNV-VNSMKQMASIYNDLH--EQHDNEIKSLQKTLK Mbp1_EREGO ASLIHTG--DMYPSQSATSVSRAIPEV-INLMKDMADSYQFLY--EDRNQEVQDLVKMLK Mbp1_KLULA ------N--KMYPSQAATRTNRIIPEV-INMMKEMANSYQNAY--QKRQNEVLQMERTVK Mbp1_YARLI -----PPYQMLHESETAIAAHN-LAGTVVHNLQVLAHAFDAEL--KEKDADVQQVRQMAT Mbp1_COPCI APAN-HDRPPLHYSAAAQKASTRCVNDMASMLDSLAASFDQEL--RDKERDMAQAQALLT Mbp1_USTMA --------SSLHTSEAGQRTAGRAVTLMSNLLHSLADSYDSEI--NTAEKKLTQAHGLLK Mbp1_SCHPO --------PAIISPSCSSHAFVKAIPSISSKFSQLAEEYESQL--REKEEDLIRANRLKQ . Ankyrin 3D --t---tt----HHHHHHH---HHHHH-HHH Annotation CCCCCCC--CCCCCCCCCCCCCCCC Mbp1_ASPFU QLEVDRQKIQEQTAALEAKETEGEPVEAQ----LERYERLRSTY--E------------- Mbp1_ASPNI QLEQDRQKIRRQYDALAAKEAAEESSDAQ----LGRYEQMRDNY--E------------- Mbp1_ASPTE QLELDRQKIKQQTAALSAKEAEEEPVDTQ----LARYEQLRASY--E------------- Mbp1_CRYNE HATRALADKRQHLHRAQEKLATMQLFEQRSENVRRIMDAIAAGTLLTPAEFTGRTQTMHE Mbp1_GIBZE TTSTQLGEARRSLEHLSATLKKQQLA-------KQKVANLSHA----------------- Mbp1_MAGGR LTTTDVNDLRRKLDEAQARVKAQQLA-------RQKVTNLQRA----------------- Mbp1_NEUCR VTSSQVGDARRTLESLQEKLKAQQLA-------KQKIVNFNRA----------------- Mbp1_CANAL QINQIKLESQRKILSFFKLDHLIEELEQNKDDSQQQQQQVTDDD--DPTSVHGNDLHLDF Mbp1_DEBHA AIGHEKLLSQRAVLQFFKLEYLIDDIMADYDQN------------------NSDNLIIDT Mbp1_PICST SINTEKLVSQKAILSFFKLEYLIEDLERVNKE------------------TNPQELSLDF Mbp1_CANGL SIKRTVHSTDNRIREILET---------D--------------------------ADADI Mbp1_SACCE SISKTKIQVSLKTLEVLKESSKDENGEAQ--------------------------TNDDF Annotation C
Mbp1_EREGO SMSATVTSLDMKVLEILEVK-----------------------------------DMNNI Mbp1_KLULA SMKKTITSVEMKLLEALNLK-----------------------------------ETDNV Mbp1_YARLI KMEEDIAATNEAIREYEAKHGTAEELEK-------------------------------- Mbp1_COPCI NIQAEILESQRTVLQLR---QQAEGLSQA----KQRLADLENA----LQDKMGRRYRLGF Mbp1_USTMA QIQTEIEDSAKVAEALH---HEAQGVDEE----RKRVDSLQLA----LKHAINKRARDDL Mbp1_SCHPO DTLNEISRTYQELTFLQ---KNNPTY-------SQSMENLIRE-AQETYQQLSKRLLIWL Mbp1_ASPFU ------------------------------------SLLEQIQQVRLKERLTSMPPPAKE Mbp1_ASPNI ------------------------------------SLLEQIQRARLKERLASTPVPTQT Mbp1_ASPTE ------------------------------------SLLEHIQQARLKERVASMPIPTKE Mbp1_CRYNE KSTGQLPPLAFRHVPG--------------------LALDASSQSQLNGAPPSTPLSVED Mbp1_GIBZE ---REAEQVRLMQEQ------SRASQPNPSSS------WETELSAMLEAADDTSDG---- Mbp1_MAGGR ---EERERYRLTQLE------QTTGRRDIASAN----GWEAESNTLLATINATTNG---- Mbp1_NEUCR ---CEEEEQILIELE------QRHGRLDVASAN----AWEMELESALEIVKTQSPKGL-- Mbp1_CANAL KRDHILQEEIYRLMNDLTYQELHQQDELDKVEHSYRMTKERLH-EKVLDASSF----VID Mbp1_DEBHA EKDRIIQDEINRLISDLSFQFLQRKDQLDQVFMKYKAISSAIQNTKVAELAST----LSQ Mbp1_PICST KRDQIIQDEIHRLINDLTYQFLQKKEDLYQLHQKYILVNEKVQ----------------- Mbp1_CANGL SSAILAQEKDITELK------IEAENHL--------RKLKNQFEYLQKQRLLKLTEYHN- Mbp1_SACCE EILSRLQEQNTKKLR------KRLIRYK--------RLIKQKLEYRQTVLLNKLIEDETQ Mbp1_EREGO TYEMDSLKENIAGLK------QKLSEKQ--------KVLVSLLEKSQRVTLRKCVEEEKK Mbp1_KLULA DIVLNDRKEKIDELQ------RRIATDK--------RVLINRLEEGQVKLIRKFVDEETK Mbp1_YARLI ---------LASEAE------ERVTTRV--------NQLRKVFERSQAKGLAMLVAEEER Mbp1_COPCI EKWIKDE-----------------------------ETREKVIRDAANGDLVLTPATTSY Mbp1_USTMA ER--RWS-----------------------------EGKQAIKRARLQAGLEPGALSTSN Mbp1_SCHPO EA---------RQIFDLERSLKPHTSLSISFPSDF------------------------- Annotation xxxx------xxxxxxx--------xxxxxxx Mbp1_ASPFU NMMPS--------------------------------------SSDQNQL-LITYQLARQ Mbp1_ASPNI AVIGS-------------------------------------SSPEQDRL-LTTFQLSRA Mbp1_ASPTE Q--AE-------------------------------------SSKDTSQL-TTVFQLAQK Mbp1_CRYNE QEDI------------------------------ALPERDDP----------ECLVKLRR Mbp1_GIBZE ------------------------------------------EFGGEGLLP-SAAVLEAR Mbp1_MAGGR ------------------------------------------EPDADAKLP-SSALLRAR Mbp1_NEUCR ------------------------------------------DPDSRPSLP-SAAVLRAR Mbp1_CANAL QTHQQ-------------------------------------GNVH------EQLELAKQ Mbp1_DEBHA HESNS-------------------------------------SSTEDETP-SEQVRLSIE Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ---GE-------------------------------------HNDTDNTL-DNKIEICKQ Mbp1_SACCE ATTNN-------------------------------------TVEKDNNT-LERLELAQE Mbp1_EREGO AIESVI--------------------------------AAPADDATHSSKE-TLADDLRE Mbp1_KLULA NV---------------------------------------EGKTTDGEESEDIEALLKE Mbp1_YARLI EI-------------------------------------------SREQT-KGEFKTAKE Mbp1_COPCI TV--DEDGDSDSGSNGDKNKGKRKAQVQQEEVSDLVELYSNIPTDPEELR-KQCEALREE Mbp1_USTMA ATNAPATGDQKSKDDA-------------KSLIEALPAGTNVKTAIA--------ELRKQ Mbp1_SCHPO -------------------LKKEDGLSLNNDF--KKPACNN-----VTNS-DEYEQLINK Mbp1_ASPFU LCSLQKARRAAVRDLAQQTADAGV------------------------------------ Mbp1_ASPNI LCSEQKIRRAAVKELAQQRADAGV------------------------------------ Mbp1_ASPTE LCAAQKARRAAVKELAQQTADAGV------------------------------------ Mbp1_CRYNE MALWEDRIAEVLEDKIRAMEGEGV------------------------------------ Mbp1_GIBZE VRAVKK-RCESTRK------------------------------------------MVSA Mbp1_MAGGR IEAVKK-QTESTRQ------------------------------------------SVVA Mbp1_NEUCR IKALRA-RSSKTRQ------------------------------------------AVAA Mbp1_CANAL LQVEIIKRKKLVDEISKLTKNVPLPE------------------------NPNAKTIIDT Mbp1_DEBHA LQTQIVKYKQMLHKLHQQHLQVPLSSLNDNTDTKENKENIKEESQTNDTAEPAPHSVIAK Mbp1_PICST LTEEIIKCKKLSQQLYKQQMVVPIPQ-----------TSIDKENNSTPT-GSSSNSIVAK Mbp1_CANGL ISVLQIERKRKISE------------------------------------------LISH Mbp1_SACCE LTMLQLQRKNKLSS------------------------------------------LVKK Mbp1_EREGO LTVLQLRRKHKINR------------------------------------------LIEL Mbp1_KLULA LVLIQLKRKRKLNQ------------------------------------------IIDV Mbp1_YARLI LTDLQHGRKDLVDDVVELFANAGV------------------------------------ Mbp1_COPCI VSQSRKRRKAMFDELVTFQAEAGT------------------------------------ Mbp1_USTMA LSQVQANKTELVDKFVARAREQGT------------------------------------ Mbp1_SCHPO LTSLQASRKKDTLYIRKLYEELGI------------------------------------ : Mbp1_ASPFU ----S-TKFDVHRRLVALAT-GLKEEELD-PMAAELAETLEFDRMNGR-GPGGESPE--- Mbp1_ASPNI ----S-TKFDVHRKLVALAT-GLKEEELD-PMAAELAETLEFDRMNGK-GVGPESPE--- Mbp1_ASPTE ----S-TKFDVHRKLVALAT-GLKEEELD-PMAAELAEALEFDRMNGK-GNGAESPD--- Mbp1_CRYNE ------DRAVKYRKLVSVCA-KVPVDKVD-SMLDGLVAAVESEGQG-------------- Mbp1_GIBZE LKGRSRDTEVKYRRVVALCT-GVQEDEVD-AVIDGLLKAVESEQEE-------------- Mbp1_MAGGR LKGRSREVEGRYRHLVALAT-KCRDEDVD-STMEGLLKAVESEKGE-------------- Mbp1_NEUCR LQAQSKEKELKYRRLVSLCT-RRPEIEVE-ALLDTLTRAVESEKPE-------------- Mbp1_CANAL YPS-T-DKLYKYCKLISLSC-GIPMDEIE-TSIDAMEESLVKK----------------- Mbp1_DEBHA YPK-D-DKLHKYCKLIALCC-GMNFNDVE-NSIDLIEQSLSKSAPNM------------- Mbp1_PICST YPH-D-NLLSKYCHLIAQCC-GMDFDDVE-GSIDEIEQSLLKSN--V------------- Mbp1_CANGL YED-S-RKIHKYRRMISEGT-EMKTEEVD-GCLDIILQTLINNSS--------------- Mbp1_SACCE FED-N-AKIHKYRRIIREGT-EMNIEEVD-SSLDVILQTLIANNNK---NKGAEQII--- Mbp1_EREGO LCG-N-SKIHKFRKMISQGT-DMDISEVD-NFLDVIFQQLNEDEENTN-NGG-------- Mbp1_KLULA ITD-N-SKVYKYRKMISQGT-DIDVSDVD-ECLDVIYQTLSKEG---------------- Mbp1_YARLI ----G-EKMNEYRRLVAMSC-GVKVEDID-GLLDGIEKALLEGER--------------- Mbp1_COPCI ----S-GRMSDYRRLIAAGCGGLEPLEID-SVLGMLLETLEAE----------------- Mbp1_USTMA ----G-RTMAAYRRLIAAGCGGIAPDEVD-AVVGVLCELLQESHTGARAGAGGERDDRAR Mbp1_SCHPO ----D-DTVNSYRRLIAMSC-GINPEDLSLEILDAVEEALTREK---------------- . ::: .:. : : Mbp1_ASPFU ---------PVQKR---------------------------------------------- Mbp1_ASPNI ---------A-------------------------------------------------- Mbp1_ASPTE ---------L-------------------------------------------------- Mbp1_CRYNE ------------------------------------------------------------ Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR ------------------------------------------------------------ Mbp1_NEUCR ------------------------------------------------------------ Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ---------TISNA---------------------------------------------- Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA DVAMMLKAFPVYSRCIVMNRQLAVTRYPCCRLLFYSLPCRTNMISGLWMQSDSVAAVLAR Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU ------------------------------------------------------------ Mbp1_ASPNI ------------------------------------------------------------ Mbp1_ASPTE ------------------------------------------------------------ Mbp1_CRYNE ------------------------------------------------------------ Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR ------------------------------------------------------------ Mbp1_NEUCR ------------------------------------------------------------ Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ------------------------------------------------------------ Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA SNAVLRISPCPKCARMSKLQAHLYEASAARLCGGKMLRRTLALFSEAARSSSSSSASAAA Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU ----------LPS----------------------------------------------- Mbp1_ASPNI ------------D----------------------------------------------- Mbp1_ASPTE ------------E----------------------------------------------- Mbp1_CRYNE ------------------------------------------------------------ Mbp1_GIBZE ------------------------------------------------------------ Mbp1_MAGGR ------------------------------------------------------------ Mbp1_NEUCR ------------------------------------------------------------ Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ------------------------------------------------------------ Mbp1_PICST ------------------------------------------------------------ Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE ----------N------------------------------------------------- Mbp1_EREGO ------------------------------------------------------------ Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI ------------------------------------------------------------ Mbp1_USTMA SSSASILTSHLSKAHLPPSLARSAKPHKNLYQMLSTLPKDGVGARVRQRRWAAKGLDVSH Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU -----------------------------QREPSSLPFSGPPVSVDA------------- Mbp1_ASPNI -----------------------------HKDSASLPFPGPVVSVDA------------- Mbp1_ASPTE -----------------------------HKDSASFPFPEPTISVDA------------- Mbp1_CRYNE ----------------------------LDFSRASNFVNRIKATK-S------------- Mbp1_GIBZE ----------------------------LEINRVRRFLGGVEGV--Q------------- Mbp1_MAGGR ----------------------------LEIGRVRRFLGGVEGVI-G------------- Mbp1_NEUCR ----------------------------LEIARVRRFLGGVEGVV-H------------- Mbp1_CANAL ------------------------------------------------------------ Mbp1_DEBHA ----------------------------------------------Q------------- Mbp1_PICST ----------------------------------------------K------------- Mbp1_CANGL ------------------------------------------------------------ Mbp1_SACCE --------------------------------------------SHA------------- Mbp1_EREGO ---------------------------------HTNYNG--------------------- Mbp1_KLULA ------------------------------------------------------------ Mbp1_YARLI ------------------------------------------------------------ Mbp1_COPCI -----------------------------DPSSTSATWSGSKGQQTG------------- Mbp1_USTMA DVDLKAHLAKLHHTGATKTNKDEGHLCYWEITKVRLKDGGNHGKAWGRFVWRERNAGVVK Mbp1_SCHPO ------------------------------------------------------------ Mbp1_ASPFU --------------------------------------------- Mbp1_ASPNI --------------------------------------------- Mbp1_ASPTE --------------------------------------------- Mbp1_CRYNE --------------------------------------------- Mbp1_GIBZE --------------------------------------------- Mbp1_MAGGR --------------------------------------------- Mbp1_NEUCR --------------------------------------------- Mbp1_CANAL --------------------------------------------- Mbp1_DEBHA --------------------------------------------- Mbp1_PICST --------------------------------------------- Mbp1_CANGL --------------------------------------------- Mbp1_SACCE --------------------------------------------- Mbp1_EREGO ------HVSCAILDTVEGYGIENIENKRGT-------SQNDGPAK Mbp1_KLULA --------------------------------------------- Mbp1_YARLI --------------------------------------------- Mbp1_COPCI --------------------------------------------- Mbp1_USTMA QGQAQAKLTKVCLSMVVAHPGKPITKAESGERIPGALKYCWDLAH Mbp1_SCHPO ---------------------------------------------
Notes