Difference between revisions of "BIO project GO-term table"

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GO term Table
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Constructing the GO term table
 
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==Extracting Gene functions from GO and GOA==
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==Extracting gene functions from GO and GOA==
  
This table below of selected GO terms with human gene annotations in GOA is a starting point for function definition and gene selection.
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The [http://steipe.biochemistry.utoronto.ca/abc/students/index.php/BCH441_2016_project_GO_term_table table of selected biological process GO terms] a starting point for system definition and gene selection.
  
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{{Vspace}}
  
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The objective of selecting GO terms from the ontology is to find nodes that have a small number of genes associated to them (or their children). If the number of annotated genes is too small, not enough may be known about the system to usefully model it. If the number is too large, modelling the system will be too time consuming for the scope of a class project. It is also highly likely that the system should actually be broken down into subsystems, which ought to be modelled individually. I have chosen GO terms with from three to five annotated genes as a cutoff that seems workable.
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Roughly, this selection works as follows:
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1. Retrieve the ontology terms, and the list of annotated human genes from the database.<br />
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2. Remove all terms that are not in the ''biological process'' ontology.<br />
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3. Associate all human genes with their respective terms.<br />
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4. Remove all terms that are leafs (no children) AND have no genes annotated.<br />
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5. For each term, find all descendants.<br />
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6. Of all descendants, collect all annotated genes.<br />
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7. Make the list of genes unique. This is important since there may be more than one path to a gene and we don't want to double count it.<br />
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8. Store the number of genes associated to a term and its descendants.<br />
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9. Select terms that have 3 to 5 associated genes.<br />
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10. Remove terms that contain certain keywords that may make the process less suitable for our purposes, such as "development", "morphogenesis", "behavior".<br />
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11. Write the remaining terms into a Wiki table format, with links to GO terms and genes.<br />
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Details below.
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{{Vspace}}
  
===Creation of the Function Table===
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===Creation of the Process Table===
  
The Function Table was created in the following steps:
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The Process Table was created in the following steps:
:1. I downloaded the file <code>gene_association.goa_human</code> from its [ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/HUMAN/ '''GOA''' repository at the EBI]. The file contains gene names and GO terms - here is an (abridged) example:
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:'''1.''' I downloaded the most recent version of <code>goa_human.gaf</code> from the [ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/HUMAN/ '''GOA''' repository at the EBI], released on November 22. 2016. The file contains gene names and GO terms - here is one line of the contents (selected columns):
  UniProtID  GeneName GOtermID    Description                         taxID
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  UniProtID  GeneSymbol GOtermID    Reference      EvidenceCode  Description               taxID
  A0A183    LCE6A     GO:0031424 Late cornified envelope protein 6A taxon:9606
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  Q14209     E2F2        GO:0051726  GO_REF:0000019 IEA           Transcription factor E2F2 taxon:9606
  
:2. I downloaded the GO Ontologies file <code>go-basic.obo</code> from its repository [http://geneontology.org/page/download-ontology at '''GO''' -the Gene Ontology Consortium]. It contains the actual ontology terms, they look like this.
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:'''2.''' I downloaded the GO term file <code>go-basic.obo</code> from its repository [http://geneontology.org/page/download-ontology at '''GO''' - the Gene Ontology Consortium]. It contains the actual ontology terms (45,896 terms), they look like this (some information omitted).
  
 
  [Term]
 
  [Term]
  id: GO:0001776
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  id: GO:0051726
  name: leukocyte homeostasis
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  name: regulation of cell cycle
 
  namespace: biological_process
 
  namespace: biological_process
  def: "The process of regulating the proliferation and elimination of cells of the
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  def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb]
immune system such that the total number of cells of a particular cell type within a
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  is_a: GO:0050794 ! regulation of cellular process
whole or part of an organism is stable over time in the absence of an outside stimulus."
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  relationship: regulates GO:0007049 ! cell cycle
  is_a: GO:0002376 ! immune system process
 
  is_a: GO:0048872 ! homeostasis of number of cells
 
  
: Note the two <code>is_a</code> relationships that indicate the '''parent''' node, of which this one is a specialization.
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: Note the <code>is_a</code> relationship that points to the '''parent''' term, <tt>GO:0050794</tt>, of which <tt>GO:0051726</tt> is a specialization. This means: the terms have parent-associations listed with them, but don't list child terms. This means we can go up to the root from each term, but we can't descend. We need to record the child terms for each node, to be able to navigate both up and down through the ontology.
  
:3. I reconstructed the DAG (Directed Acyclic Graph) by connecting each of the 40,402 nodes to its parent node.
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:'''3.''' Open this file in '''R''' and read all the terms that are labelled as <tt>namespace: biological_process</tt> into a data frame storing ID, name, definition, and parent term IDs. These are 29,309 terms. Then add each term ID to its parent terms as a child term.
  
:4. I eliminated all nodes that don't have at least one human gene in GOA annotated to it or one of its descendants. These are genes that might be specific to fungi, prokaryotes, viruses or similar.
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:'''4.''' Open the human GOA file and read all gene annotations into a data frame. These are 392,942. That's a lot - we expect at least three annotations for each of the 19,225 genes that GOA currently contains, one for each ontology, but we find on average 20 annotations. Next, add each gene symbol to the term data frame, if the annotation's GO ID is in our set.
  
:5. For each node, I counted its distance from the root node. This "depth" tells us a bit about how specific a term is.
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:'''5.''' Next, remove all terms that are leaves (i.e. they don't have children), AND have no annotated genes. These are terms that might be specific to fungi, prokaryotes, viruses or similar. Since our goal is to count the number of genes associated with each term, those can't contribute since their own count is zero. Deleting those nodes obviously creates new leaves in the ontology, so this process has to be iterated, until no more nodes can be removed. This deletes 11,733 terms from the ontology.
  
:6. For each node, I counted how many human genes have been specifically annotated to it. This helps us a bit to indetify categories that are overly broad.
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:'''6.''' We need a function that finds all descendants of a term. In order to find and visit all descendants, start from a term and put its child(ren) into a queue. While the queue is not empty, remove the first ID from the queue, and add those of its children to the queue that we haven't visited before.
  
:7: I wrote this information to file for the '''biological process''' ontology. The result has 11,927 nodes, one per line, and looks like this:
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:'''7.''' For each term, count all genes that are associated to it or to any of its descendants. The root term, <tt>GO:0008150</tt> has 17,030 associated genes.
  
01  GO:0002376  immune system process [ ADSS ... 17 genes ]
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:'''8.''' Next, select all terms that have from three to five associated genes AND contain none of a list of keywords. These keywords include: "proliferation", "development", "morphogenesis", "regression", "induction", "maturation", "formation", "growth", "*bolic process", "biosynthetic process", and "behavior". I feel that even though the GO terms may be manageable, the actual '''system''' would likely contain an unwieldy number of genes. I also removed all "positive regulation of ...", and "negative regulation of ..." terms. These always have a parent term"regulation of ..." and that term would be the right one to consider.
05      GO:0001776  leukocyte homeostasis [MEN1, FLT3, NKX2-3]
 
06        GO:0001780 neutrophil homeostasis [ MECOM ... 13 genes ]
 
  
:Here, ''neutrophil homeostasis'' has 13 annotated genes, it is six steps removed from the root. Its parent is ''leukocyte homeostasis'' which itself is a specialization (a descendant) of an ''immune system process''. The intermediate nodes are not shown because there are no genes directly annotated to these terms. Now consider what it means to find a gene at these levels: <code>MECOM</code> is involved in the homeostasis (keeping cell-numbers constant) of neutrophil white blood cells. <code>MEN1</code> is also involved in white blood cell homeostasis, but it could either target several cell types, or it is not known which cell type it targets. Thus it is annotated to a higher node. <code>ADSS</code> seems to be a gene for which we know it is involved in the immune system, but we don't know what it does there. This illustrates how partial knowledge can be represented in this data structure, and you can easily imagine that, as we learn more about biology, we move annotations down to more precise locations, or create new nodes to represent new knowledge.
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:'''9.''' Finally, the 1,224 selected terms were written into a [http://steipe.biochemistry.utoronto.ca/abc/students/index.php/BCH441_2016_project_GO_term_table table in an editable Wiki code format], including links to GO and UniProt.
  
:8. Next, I selected from this list. For this project we are looking for terms that give a good approximation of a cellular function, without being either too broad or too specialized. I selected nodes that have from 1 to 4 annotated genes at a depth between 2 and 5, and I excluded terms with keywords that indicate a role in a higher function of the organism such as "morphogenesis", "development" and "behavior". This yields 541 processes represented by 1,214 unique annotated genes.
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{{Vspace}}
  
:9. To create the table you see below, I wrote the output in HTML table format to file, while adding links to the UniProt entry for the gene name. The gene names come from [http://www.genenames.org/ '''HGNC'''] so I would expect all of the genes to be findable at UniProt.
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===How to use the table to adopt a function and define a "system" for the project===
  
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{{Vspace}}
  
===How to use the table to adopt a function for the project===
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I have randomly chosen a term – <tt>[http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0001845 GO:0001845] (phagolysosome assembly)</tt> – to illustrate the process:
  
;I have randomly chosen a function and gone trhough the first stage of the project to illustrate the process:
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{{Vspace}}
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:'''1.''' Browse the table and find a function that interests you. It's very diverse and will give you a good first sense of the complexity of functions in the cell and our state of knowledge about them. Have a look at the [http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0001845 term information]. There is probably a link to an [http://gowiki.tamu.edu/wiki/index.php/Category:GO:0001845_!_phagolysosome_assembly associated "GONUTS" page] with more information.
  
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:'''2.''' Look at the function information available when you follow the links of the annotated genes to UniProt. Most of these genes have more than one GO term annotated to them, and taken together, these GO terms shed more light on how the "system" is more and different than its annotated GO terms. For example from the genes in <tt>[http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0001845 GO:0001845]</tt> let's look at [http://www.uniprot.org/uniprot/?query=gene:SRPX+AND+taxonomy:9606+AND+reviewed:yes "SRPX"]. This gene codes for [http://www.uniprot.org/uniprot/P78539 P78539 (SRPX)]. Here are the annotated processes in which this protein participates:
:'''1.''' Browse the table and find a function that interests you. Its very diverse and will give you a good first sense of the complexity of functions in the cell and our state of knowledge about them.
 
:'''2.''' Look at the function information available at UniProt. Most of these genes have more than one GO term annotated to them. For example I could choose (at random) [http://www.uniprot.org/uniprot/P78539 SRPX], which plays a role in '''phagolysosome assembly'''. Here are the annotated processes in which this protein participates:
 
 
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*[http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0006914 autophagy]
 
*[http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0006914 autophagy]
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Just looking at these processes tells me a lot. The annotation is for '''one protein''', but it is implied in several aspects of biology. Some of them are '''causal to others''', and some of them are '''generalizations'''. Here, the ''phagolysosome'' needs to be assembled in order to function. Once it has been made, this enables stress response, and contact inhibition, likely via apoptotic pathways and autophagy. This '''phagolysosome assembly''' sounds like a good system to work on. But is the term too broad, or too narrow? Could I find a better name for it?
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:Just looking at these processes tells me a lot. The annotation is for '''one protein''', but it is implied in several aspects of biology. Some of them are '''causal to others''', and some of them are '''generalizations'''. Here, the ''phagolysosome'' needs to be assembled in order to function. Once it has been made, this enables stress response, and contact inhibition, likely via apoptotic pathways and autophagy. This '''phagolysosome assembly''' sounds like a good system to work on. But is the term too broad, or too narrow? Could I find a better name for it?
  
:'''3.''' Follow the link to the [http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0001845 '''phagolysosome assembly'''] GOterm page at QuickGO, and explore the tabs that contain ancestral nodes and child nodes:
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:'''3.''' Follow the link to the [http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0001845 '''phagolysosome assembly'''] GOterm page at QuickGO, and explore the tabs that contain the Ancestor Chart and the Child Terms:
  
 
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{{Vspace}}
  
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Explore how many proteins are annotated to this term. There are probably '''VERY''' many - so set a taxon filter on this table (taxon: <tt>9606</tt>) to view only human proteins.
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{{Vspace}}
  
As a result of the exploration I see:
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As a result of my first exploration I see:
* There are 20 to 30 proteins annotated to this process;
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* There are probably around 20 proteins that I'll need to cnsider as system components;
* Most of them are not human, but from closely related species (e.g. baboon), that will probably allow inference from homology;
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* most of them are RAB genes which have a reasonably well understood function. It will be interesting to find out how this function enables the process;
* If I set a filter to show only human proteins, I see that most of them are RAB genes which have a reasonably well understood functio. It will be interesting to find out how this function enables the process;
 
 
* The mechanism of this system will likely include proteins that are specific to this process, and others that are involved in membrane fusion in a general sense and are recruited to this specific task.
 
* The mechanism of this system will likely include proteins that are specific to this process, and others that are involved in membrane fusion in a general sense and are recruited to this specific task.
  
This actually looks like an ideal starting point to define the components of a system. For now, I would be oK with calling it the "Phagosome / Lysosome Fusion System".
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This looks like an good starting point to define the components of a system. For now, I would be oK with calling it the "Phagosome / Lysosome Fusion System".
 
 
 
 
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===What to submit for Part 1 of the project===
 
 
 
* Head over to [http://steipe.biochemistry.utoronto.ca/abc/students/index.php/User:Boris/BCH441_Project_2015 '''my 2015 project page on the student wiki'''].
 
* Copy the page content Wiki code and use it to create a subpage of your user space on the Student Wiki.
 
* Edit the page for your adopted system. Make sure the result contains all elements of the original (and none of the elements that are specific to me or the template project.
 
 
 
  
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{{Vspace}}
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===Considerations for choosing a system===
  
===The Function Table===
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'''Keep your systems simple.''' I would avoid choosing systems/processes that integrate sensory, nervous, hormonal and cellular components. This may become too complex. Narrowing it down, to a manageable "subsystem" is a valuable exercise in itself. Such a system may implement
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*integrating input,
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*transmitting input signals to their effectors,
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*regulating the process,
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*providing resources,
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*defining setpoints,
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*assembling or disassembling the system,
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*mediating interactions with other systems,
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*or similar...
  
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'''Keep your systems manageable.''' When considering how many genes are associated with a system, check the taxon section of the relevant GO terms' statistic on QuickGO. The number of genes involved in the process in humans is likely as large as the largest number for ANY species - although many of the human genes may not have been annotated for that process (yet). For example, if the mouse (mus musculus) has 20 annotated genes and humans have only two, that probably does not mean humans can achieve with only two genes that for which the mouse needs twenty. In this situation, looking for orthologues of mouse genes should lead you to human candidate genes. But as a corollary, if the mouse has many, many genes annotated, that particular process might not be so suitable for this project after all.
  
<table>
 
<tr class="sh">
 
<td><b>Depth</b></td>
 
<td><b>GO Term</b></td>
 
<td><b>Text</b></td>
 
<td><b>Genes</b></td>
 
</tr>
 
<tr><td colspan="4" class="sp"></td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001776</td><td>leukocyte homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:MEN1+AND+taxonomy:9606+AND+reviewed:yes MEN1], [http://www.uniprot.org/uniprot/?query=gene:FLT3+AND+taxonomy:9606+AND+reviewed:yes FLT3], [http://www.uniprot.org/uniprot/?query=gene:NKX2-3+AND+taxonomy:9606+AND+reviewed:yes NKX2-3]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0016445</td><td>somatic diversification of immunoglobulins</td><td>[http://www.uniprot.org/uniprot/?query=gene:AICDA+AND+taxonomy:9606+AND+reviewed:yes AICDA], [http://www.uniprot.org/uniprot/?query=gene:CTNNBL1+AND+taxonomy:9606+AND+reviewed:yes CTNNBL1], [http://www.uniprot.org/uniprot/?query=gene:RAG2+AND+taxonomy:9606+AND+reviewed:yes RAG2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002366</td><td>leukocyte activation involved in immune response</td><td>[http://www.uniprot.org/uniprot/?query=gene:SH2D1B+AND+taxonomy:9606+AND+reviewed:yes SH2D1B], [http://www.uniprot.org/uniprot/?query=gene:CLEC7A+AND+taxonomy:9606+AND+reviewed:yes CLEC7A], [http://www.uniprot.org/uniprot/?query=gene:SYK+AND+taxonomy:9606+AND+reviewed:yes SYK]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0019724</td><td>B cell mediated immunity</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLA2+AND+taxonomy:9606+AND+reviewed:yes SLA2], [http://www.uniprot.org/uniprot/?query=gene:MSH2+AND+taxonomy:9606+AND+reviewed:yes MSH2], [http://www.uniprot.org/uniprot/?query=gene:FAS+AND+taxonomy:9606+AND+reviewed:yes FAS]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0002679</td><td>respiratory burst involved in defense response</td><td>[http://www.uniprot.org/uniprot/?query=gene:NCF1+AND+taxonomy:9606+AND+reviewed:yes NCF1], [http://www.uniprot.org/uniprot/?query=gene:MPO+AND+taxonomy:9606+AND+reviewed:yes MPO], [http://www.uniprot.org/uniprot/?query=gene:PIK3CG+AND+taxonomy:9606+AND+reviewed:yes PIK3CG], [http://www.uniprot.org/uniprot/?query=gene:PIK3CD+AND+taxonomy:9606+AND+reviewed:yes PIK3CD]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0045728</td><td>respiratory burst after phagocytosis</td><td>[http://www.uniprot.org/uniprot/?query=gene:HCK+AND+taxonomy:9606+AND+reviewed:yes HCK], [http://www.uniprot.org/uniprot/?query=gene:SELK+AND+taxonomy:9606+AND+reviewed:yes SELK]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0002352</td><td>B cell negative selection</td><td>[http://www.uniprot.org/uniprot/?query=gene:BAX+AND+taxonomy:9606+AND+reviewed:yes BAX], [http://www.uniprot.org/uniprot/?query=gene:BAK1+AND+taxonomy:9606+AND+reviewed:yes BAK1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002367</td><td>cytokine production involved in immune response</td><td>[http://www.uniprot.org/uniprot/?query=gene:MR1+AND+taxonomy:9606+AND+reviewed:yes MR1], [http://www.uniprot.org/uniprot/?query=gene:NOD2+AND+taxonomy:9606+AND+reviewed:yes NOD2]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0002377</td><td>immunoglobulin production</td><td>[http://www.uniprot.org/uniprot/?query=gene:FAS+AND+taxonomy:9606+AND+reviewed:yes FAS], [http://www.uniprot.org/uniprot/?query=gene:IL7R+AND+taxonomy:9606+AND+reviewed:yes IL7R]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002381</td><td>immunoglobulin production involved in immunoglobulin mediated immune response</td><td>[http://www.uniprot.org/uniprot/?query=gene:HLA-DQB1+AND+taxonomy:9606+AND+reviewed:yes HLA-DQB1], [http://www.uniprot.org/uniprot/?query=gene:HLA-DRB1+AND+taxonomy:9606+AND+reviewed:yes HLA-DRB1], [http://www.uniprot.org/uniprot/?query=gene:NOD2+AND+taxonomy:9606+AND+reviewed:yes NOD2]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0002513</td><td>tolerance induction to self antigen</td><td>[http://www.uniprot.org/uniprot/?query=gene:LYN+AND+taxonomy:9606+AND+reviewed:yes LYN], [http://www.uniprot.org/uniprot/?query=gene:FOXP3+AND+taxonomy:9606+AND+reviewed:yes FOXP3], [http://www.uniprot.org/uniprot/?query=gene:TGFB1+AND+taxonomy:9606+AND+reviewed:yes TGFB1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002384</td><td>hepatic immune response</td><td>[http://www.uniprot.org/uniprot/?query=gene:IL6+AND+taxonomy:9606+AND+reviewed:yes IL6], [http://www.uniprot.org/uniprot/?query=gene:IL6R+AND+taxonomy:9606+AND+reviewed:yes IL6R]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0002418</td><td>immune response to tumor cell</td><td>[http://www.uniprot.org/uniprot/?query=gene:PRF1+AND+taxonomy:9606+AND+reviewed:yes PRF1], [http://www.uniprot.org/uniprot/?query=gene:MICA+AND+taxonomy:9606+AND+reviewed:yes MICA]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0042092</td><td>type 2 immune response</td><td>[http://www.uniprot.org/uniprot/?query=gene:IL4+AND+taxonomy:9606+AND+reviewed:yes IL4], [http://www.uniprot.org/uniprot/?query=gene:BCL6+AND+taxonomy:9606+AND+reviewed:yes BCL6], [http://www.uniprot.org/uniprot/?query=gene:IL18+AND+taxonomy:9606+AND+reviewed:yes IL18], [http://www.uniprot.org/uniprot/?query=gene:IL10+AND+taxonomy:9606+AND+reviewed:yes IL10]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0002495</td><td>antigen processing and presentation of peptide antigen via MHC class II</td><td>[http://www.uniprot.org/uniprot/?query=gene:MARCH1+AND+taxonomy:9606+AND+reviewed:yes MARCH1], [http://www.uniprot.org/uniprot/?query=gene:MARCH8+AND+taxonomy:9606+AND+reviewed:yes MARCH8]</td></tr>
 
<tr class="s2"><td>2</td><td>GO:0045058</td><td>T cell selection</td><td>[http://www.uniprot.org/uniprot/?query=gene:CD1D+AND+taxonomy:9606+AND+reviewed:yes CD1D], [http://www.uniprot.org/uniprot/?query=gene:CD4+AND+taxonomy:9606+AND+reviewed:yes CD4], [http://www.uniprot.org/uniprot/?query=gene:CD74+AND+taxonomy:9606+AND+reviewed:yes CD74]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0043366</td><td>beta selection</td><td>[http://www.uniprot.org/uniprot/?query=gene:ZAP70+AND+taxonomy:9606+AND+reviewed:yes ZAP70], [http://www.uniprot.org/uniprot/?query=gene:SYK+AND+taxonomy:9606+AND+reviewed:yes SYK]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0043368</td><td>positive T cell selection</td><td>[http://www.uniprot.org/uniprot/?query=gene:THEMIS+AND+taxonomy:9606+AND+reviewed:yes THEMIS], [http://www.uniprot.org/uniprot/?query=gene:BCL11B+AND+taxonomy:9606+AND+reviewed:yes BCL11B]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0045061</td><td>thymic T cell selection</td><td>[http://www.uniprot.org/uniprot/?query=gene:CARD11+AND+taxonomy:9606+AND+reviewed:yes CARD11], [http://www.uniprot.org/uniprot/?query=gene:JAG2+AND+taxonomy:9606+AND+reviewed:yes JAG2], [http://www.uniprot.org/uniprot/?query=gene:GATA3+AND+taxonomy:9606+AND+reviewed:yes GATA3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0050902</td><td>leukocyte adhesive activation</td><td>[http://www.uniprot.org/uniprot/?query=gene:CX3CL1+AND+taxonomy:9606+AND+reviewed:yes CX3CL1], [http://www.uniprot.org/uniprot/?query=gene:SELPLG+AND+taxonomy:9606+AND+reviewed:yes SELPLG]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0018916</td><td>nitrobenzene metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:GSTM1+AND+taxonomy:9606+AND+reviewed:yes GSTM1], [http://www.uniprot.org/uniprot/?query=gene:GSTM2+AND+taxonomy:9606+AND+reviewed:yes GSTM2], [http://www.uniprot.org/uniprot/?query=gene:GSTM3+AND+taxonomy:9606+AND+reviewed:yes GSTM3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006579</td><td>amino-acid betaine catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:BHMT+AND+taxonomy:9606+AND+reviewed:yes BHMT], [http://www.uniprot.org/uniprot/?query=gene:DMGDH+AND+taxonomy:9606+AND+reviewed:yes DMGDH]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0033076</td><td>isoquinoline alkaloid metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP2D6+AND+taxonomy:9606+AND+reviewed:yes CYP2D6], [http://www.uniprot.org/uniprot/?query=gene:TH+AND+taxonomy:9606+AND+reviewed:yes TH], [http://www.uniprot.org/uniprot/?query=gene:DDC+AND+taxonomy:9606+AND+reviewed:yes DDC]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0000255</td><td>allantoin metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:STAT5B+AND+taxonomy:9606+AND+reviewed:yes STAT5B], [http://www.uniprot.org/uniprot/?query=gene:STAT5A+AND+taxonomy:9606+AND+reviewed:yes STAT5A], [http://www.uniprot.org/uniprot/?query=gene:GHR+AND+taxonomy:9606+AND+reviewed:yes GHR]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0009822</td><td>alkaloid catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP2D6+AND+taxonomy:9606+AND+reviewed:yes CYP2D6], [http://www.uniprot.org/uniprot/?query=gene:CYP3A4+AND+taxonomy:9606+AND+reviewed:yes CYP3A4], [http://www.uniprot.org/uniprot/?query=gene:CYP3A5+AND+taxonomy:9606+AND+reviewed:yes CYP3A5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070458</td><td>cellular detoxification of nitrogen compound</td><td>[http://www.uniprot.org/uniprot/?query=gene:GSTM1+AND+taxonomy:9606+AND+reviewed:yes GSTM1], [http://www.uniprot.org/uniprot/?query=gene:GSTM2+AND+taxonomy:9606+AND+reviewed:yes GSTM2], [http://www.uniprot.org/uniprot/?query=gene:GSTM3+AND+taxonomy:9606+AND+reviewed:yes GSTM3]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0051410</td><td>detoxification of nitrogen compound</td><td>[http://www.uniprot.org/uniprot/?query=gene:MARC1+AND+taxonomy:9606+AND+reviewed:yes MARC1], [http://www.uniprot.org/uniprot/?query=gene:MARC2+AND+taxonomy:9606+AND+reviewed:yes MARC2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0009820</td><td>alkaloid metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP2D6+AND+taxonomy:9606+AND+reviewed:yes CYP2D6], [http://www.uniprot.org/uniprot/?query=gene:CYP1A2+AND+taxonomy:9606+AND+reviewed:yes CYP1A2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0042412</td><td>taurine biosynthetic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CDO1+AND+taxonomy:9606+AND+reviewed:yes CDO1], [http://www.uniprot.org/uniprot/?query=gene:CSAD+AND+taxonomy:9606+AND+reviewed:yes CSAD]</td></tr>
 
<tr class="s2"><td>2</td><td>GO:0009056</td><td>catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:TMEM150A+AND+taxonomy:9606+AND+reviewed:yes TMEM150A], [http://www.uniprot.org/uniprot/?query=gene:CES2+AND+taxonomy:9606+AND+reviewed:yes CES2], [http://www.uniprot.org/uniprot/?query=gene:PTER+AND+taxonomy:9606+AND+reviewed:yes PTER]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0042447</td><td>hormone catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:ECE1+AND+taxonomy:9606+AND+reviewed:yes ECE1], [http://www.uniprot.org/uniprot/?query=gene:ACE+AND+taxonomy:9606+AND+reviewed:yes ACE], [http://www.uniprot.org/uniprot/?query=gene:IDE+AND+taxonomy:9606+AND+reviewed:yes IDE]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0044242</td><td>cellular lipid catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:ACADL+AND+taxonomy:9606+AND+reviewed:yes ACADL], [http://www.uniprot.org/uniprot/?query=gene:MT3+AND+taxonomy:9606+AND+reviewed:yes MT3]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0046185</td><td>aldehyde catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:ALDH3B1+AND+taxonomy:9606+AND+reviewed:yes ALDH3B1], [http://www.uniprot.org/uniprot/?query=gene:GPI+AND+taxonomy:9606+AND+reviewed:yes GPI], [http://www.uniprot.org/uniprot/?query=gene:AKR1A1+AND+taxonomy:9606+AND+reviewed:yes AKR1A1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046294</td><td>formaldehyde catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:ESD+AND+taxonomy:9606+AND+reviewed:yes ESD], [http://www.uniprot.org/uniprot/?query=gene:ADH5+AND+taxonomy:9606+AND+reviewed:yes ADH5]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0046952</td><td>ketone body catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:BDH1+AND+taxonomy:9606+AND+reviewed:yes BDH1], [http://www.uniprot.org/uniprot/?query=gene:ACAT1+AND+taxonomy:9606+AND+reviewed:yes ACAT1], [http://www.uniprot.org/uniprot/?query=gene:OXCT1+AND+taxonomy:9606+AND+reviewed:yes OXCT1], [http://www.uniprot.org/uniprot/?query=gene:OXCT2+AND+taxonomy:9606+AND+reviewed:yes OXCT2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006706</td><td>steroid catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:STS+AND+taxonomy:9606+AND+reviewed:yes STS], [http://www.uniprot.org/uniprot/?query=gene:CYP1A2+AND+taxonomy:9606+AND+reviewed:yes CYP1A2], [http://www.uniprot.org/uniprot/?query=gene:HSD17B14+AND+taxonomy:9606+AND+reviewed:yes HSD17B14], [http://www.uniprot.org/uniprot/?query=gene:CYP3A4+AND+taxonomy:9606+AND+reviewed:yes CYP3A4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0044240</td><td>multicellular organismal lipid catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:PLA2G1B+AND+taxonomy:9606+AND+reviewed:yes PLA2G1B], [http://www.uniprot.org/uniprot/?query=gene:APOA4+AND+taxonomy:9606+AND+reviewed:yes APOA4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0016139</td><td>glycoside catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:GBA2+AND+taxonomy:9606+AND+reviewed:yes GBA2], [http://www.uniprot.org/uniprot/?query=gene:GBA3+AND+taxonomy:9606+AND+reviewed:yes GBA3], [http://www.uniprot.org/uniprot/?query=gene:NAGA+AND+taxonomy:9606+AND+reviewed:yes NAGA], [http://www.uniprot.org/uniprot/?query=gene:GLA+AND+taxonomy:9606+AND+reviewed:yes GLA]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0000272</td><td>polysaccharide catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CHIT1+AND+taxonomy:9606+AND+reviewed:yes CHIT1], [http://www.uniprot.org/uniprot/?query=gene:CHIA+AND+taxonomy:9606+AND+reviewed:yes CHIA]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0016052</td><td>carbohydrate catabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:PGM2+AND+taxonomy:9606+AND+reviewed:yes PGM2], [http://www.uniprot.org/uniprot/?query=gene:PGM2L1+AND+taxonomy:9606+AND+reviewed:yes PGM2L1], [http://www.uniprot.org/uniprot/?query=gene:NAGA+AND+taxonomy:9606+AND+reviewed:yes NAGA], [http://www.uniprot.org/uniprot/?query=gene:AMY2A+AND+taxonomy:9606+AND+reviewed:yes AMY2A]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0010025</td><td>wax biosynthetic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:FAR1+AND+taxonomy:9606+AND+reviewed:yes FAR1], [http://www.uniprot.org/uniprot/?query=gene:AWAT2+AND+taxonomy:9606+AND+reviewed:yes AWAT2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070814</td><td>hydrogen sulfide biosynthetic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:MPST+AND+taxonomy:9606+AND+reviewed:yes MPST], [http://www.uniprot.org/uniprot/?query=gene:CBS+AND+taxonomy:9606+AND+reviewed:yes CBS], [http://www.uniprot.org/uniprot/?query=gene:CTH+AND+taxonomy:9606+AND+reviewed:yes CTH]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002378</td><td>immunoglobulin biosynthetic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:GALNT2+AND+taxonomy:9606+AND+reviewed:yes GALNT2], [http://www.uniprot.org/uniprot/?query=gene:PTPRC+AND+taxonomy:9606+AND+reviewed:yes PTPRC]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0006082</td><td>organic acid metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP2C8+AND+taxonomy:9606+AND+reviewed:yes CYP2C8], [http://www.uniprot.org/uniprot/?query=gene:FMO2+AND+taxonomy:9606+AND+reviewed:yes FMO2], [http://www.uniprot.org/uniprot/?query=gene:FMO1+AND+taxonomy:9606+AND+reviewed:yes FMO1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0015980</td><td>energy derivation by oxidation of organic compounds</td><td>[http://www.uniprot.org/uniprot/?query=gene:ACSM1+AND+taxonomy:9606+AND+reviewed:yes ACSM1], [http://www.uniprot.org/uniprot/?query=gene:ACADVL+AND+taxonomy:9606+AND+reviewed:yes ACADVL]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0018894</td><td>dibenzo-p-dioxin metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP1A2+AND+taxonomy:9606+AND+reviewed:yes CYP1A2], [http://www.uniprot.org/uniprot/?query=gene:CYP17A1+AND+taxonomy:9606+AND+reviewed:yes CYP17A1], [http://www.uniprot.org/uniprot/?query=gene:STAR+AND+taxonomy:9606+AND+reviewed:yes STAR], [http://www.uniprot.org/uniprot/?query=gene:CYP11A1+AND+taxonomy:9606+AND+reviewed:yes CYP11A1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0000103</td><td>sulfate assimilation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SULT2B1+AND+taxonomy:9606+AND+reviewed:yes SULT2B1], [http://www.uniprot.org/uniprot/?query=gene:PAPSS1+AND+taxonomy:9606+AND+reviewed:yes PAPSS1], [http://www.uniprot.org/uniprot/?query=gene:PAPSS2+AND+taxonomy:9606+AND+reviewed:yes PAPSS2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0019417</td><td>sulfur oxidation</td><td>[http://www.uniprot.org/uniprot/?query=gene:MICAL1+AND+taxonomy:9606+AND+reviewed:yes MICAL1], [http://www.uniprot.org/uniprot/?query=gene:MICAL2+AND+taxonomy:9606+AND+reviewed:yes MICAL2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0030388</td><td>fructose 1,6-bisphosphate metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:PFKL+AND+taxonomy:9606+AND+reviewed:yes PFKL], [http://www.uniprot.org/uniprot/?query=gene:ALDOA+AND+taxonomy:9606+AND+reviewed:yes ALDOA], [http://www.uniprot.org/uniprot/?query=gene:ALDOC+AND+taxonomy:9606+AND+reviewed:yes ALDOC], [http://www.uniprot.org/uniprot/?query=gene:ALDOB+AND+taxonomy:9606+AND+reviewed:yes ALDOB]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0017143</td><td>insecticide metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP1A1+AND+taxonomy:9606+AND+reviewed:yes CYP1A1], [http://www.uniprot.org/uniprot/?query=gene:STAR+AND+taxonomy:9606+AND+reviewed:yes STAR]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0052314</td><td>phytoalexin metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:TH+AND+taxonomy:9606+AND+reviewed:yes TH], [http://www.uniprot.org/uniprot/?query=gene:DDC+AND+taxonomy:9606+AND+reviewed:yes DDC]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0016999</td><td>antibiotic metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:TXN+AND+taxonomy:9606+AND+reviewed:yes TXN], [http://www.uniprot.org/uniprot/?query=gene:DPEP1+AND+taxonomy:9606+AND+reviewed:yes DPEP1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0042133</td><td>neurotransmitter metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:GCHFR+AND+taxonomy:9606+AND+reviewed:yes GCHFR], [http://www.uniprot.org/uniprot/?query=gene:CLN3+AND+taxonomy:9606+AND+reviewed:yes CLN3], [http://www.uniprot.org/uniprot/?query=gene:CACNA1A+AND+taxonomy:9606+AND+reviewed:yes CACNA1A], [http://www.uniprot.org/uniprot/?query=gene:AGTPBP1+AND+taxonomy:9606+AND+reviewed:yes AGTPBP1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0042180</td><td>cellular ketone metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP2B6+AND+taxonomy:9606+AND+reviewed:yes CYP2B6], [http://www.uniprot.org/uniprot/?query=gene:DHRS4+AND+taxonomy:9606+AND+reviewed:yes DHRS4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:1901661</td><td>quinone metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CRYZL1+AND+taxonomy:9606+AND+reviewed:yes CRYZL1], [http://www.uniprot.org/uniprot/?query=gene:ADH4+AND+taxonomy:9606+AND+reviewed:yes ADH4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006643</td><td>membrane lipid metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:AGMO+AND+taxonomy:9606+AND+reviewed:yes AGMO], [http://www.uniprot.org/uniprot/?query=gene:B4GALT4+AND+taxonomy:9606+AND+reviewed:yes B4GALT4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0006720</td><td>isoprenoid metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:PHYH+AND+taxonomy:9606+AND+reviewed:yes PHYH], [http://www.uniprot.org/uniprot/?query=gene:GGPS1+AND+taxonomy:9606+AND+reviewed:yes GGPS1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046485</td><td>ether lipid metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:TMEM86B+AND+taxonomy:9606+AND+reviewed:yes TMEM86B], [http://www.uniprot.org/uniprot/?query=gene:AGMO+AND+taxonomy:9606+AND+reviewed:yes AGMO], [http://www.uniprot.org/uniprot/?query=gene:HRASLS+AND+taxonomy:9606+AND+reviewed:yes HRASLS]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0072592</td><td>oxygen metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOX1+AND+taxonomy:9606+AND+reviewed:yes NOX1], [http://www.uniprot.org/uniprot/?query=gene:ME3+AND+taxonomy:9606+AND+reviewed:yes ME3], [http://www.uniprot.org/uniprot/?query=gene:FMO2+AND+taxonomy:9606+AND+reviewed:yes FMO2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0042743</td><td>hydrogen peroxide metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOX1+AND+taxonomy:9606+AND+reviewed:yes NOX1], [http://www.uniprot.org/uniprot/?query=gene:PARK7+AND+taxonomy:9606+AND+reviewed:yes PARK7]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0005976</td><td>polysaccharide metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:CHST1+AND+taxonomy:9606+AND+reviewed:yes CHST1], [http://www.uniprot.org/uniprot/?query=gene:CHST7+AND+taxonomy:9606+AND+reviewed:yes CHST7], [http://www.uniprot.org/uniprot/?query=gene:TYMS+AND+taxonomy:9606+AND+reviewed:yes TYMS]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070085</td><td>glycosylation</td><td>[http://www.uniprot.org/uniprot/?query=gene:CLN5+AND+taxonomy:9606+AND+reviewed:yes CLN5], [http://www.uniprot.org/uniprot/?query=gene:COG6+AND+taxonomy:9606+AND+reviewed:yes COG6]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0042982</td><td>amyloid precursor protein metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:KLK6+AND+taxonomy:9606+AND+reviewed:yes KLK6], [http://www.uniprot.org/uniprot/?query=gene:DLG1+AND+taxonomy:9606+AND+reviewed:yes DLG1], [http://www.uniprot.org/uniprot/?query=gene:LDLRAP1+AND+taxonomy:9606+AND+reviewed:yes LDLRAP1], [http://www.uniprot.org/uniprot/?query=gene:ACHE+AND+taxonomy:9606+AND+reviewed:yes ACHE]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:1990000</td><td>amyloid fibril formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:RIPK1+AND+taxonomy:9606+AND+reviewed:yes RIPK1], [http://www.uniprot.org/uniprot/?query=gene:RIPK3+AND+taxonomy:9606+AND+reviewed:yes RIPK3]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0044236</td><td>multicellular organismal metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:GHR+AND+taxonomy:9606+AND+reviewed:yes GHR], [http://www.uniprot.org/uniprot/?query=gene:TIPARP+AND+taxonomy:9606+AND+reviewed:yes TIPARP], [http://www.uniprot.org/uniprot/?query=gene:MNAT1+AND+taxonomy:9606+AND+reviewed:yes MNAT1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0044259</td><td>multicellular organismal macromolecule metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:TUB+AND+taxonomy:9606+AND+reviewed:yes TUB], [http://www.uniprot.org/uniprot/?query=gene:AKR1C3+AND+taxonomy:9606+AND+reviewed:yes AKR1C3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002268</td><td>follicular dendritic cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:BCL3+AND+taxonomy:9606+AND+reviewed:yes BCL3], [http://www.uniprot.org/uniprot/?query=gene:NFKB2+AND+taxonomy:9606+AND+reviewed:yes NFKB2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0014719</td><td>satellite cell activation</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT7A+AND+taxonomy:9606+AND+reviewed:yes WNT7A], [http://www.uniprot.org/uniprot/?query=gene:MEGF10+AND+taxonomy:9606+AND+reviewed:yes MEGF10]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0048143</td><td>astrocyte activation</td><td>[http://www.uniprot.org/uniprot/?query=gene:AGT+AND+taxonomy:9606+AND+reviewed:yes AGT], [http://www.uniprot.org/uniprot/?query=gene:ADORA2A+AND+taxonomy:9606+AND+reviewed:yes ADORA2A]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0072537</td><td>fibroblast activation</td><td>[http://www.uniprot.org/uniprot/?query=gene:RGCC+AND+taxonomy:9606+AND+reviewed:yes RGCC], [http://www.uniprot.org/uniprot/?query=gene:IL17A+AND+taxonomy:9606+AND+reviewed:yes IL17A], [http://www.uniprot.org/uniprot/?query=gene:IL17RA+AND+taxonomy:9606+AND+reviewed:yes IL17RA]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0016080</td><td>synaptic vesicle targeting</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLGN1+AND+taxonomy:9606+AND+reviewed:yes NLGN1], [http://www.uniprot.org/uniprot/?query=gene:SCRIB+AND+taxonomy:9606+AND+reviewed:yes SCRIB], [http://www.uniprot.org/uniprot/?query=gene:PSEN1+AND+taxonomy:9606+AND+reviewed:yes PSEN1], [http://www.uniprot.org/uniprot/?query=gene:SEPT5+AND+taxonomy:9606+AND+reviewed:yes SEPT5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0048203</td><td>vesicle targeting, trans-Golgi to endosome</td><td>[http://www.uniprot.org/uniprot/?query=gene:AP1AR+AND+taxonomy:9606+AND+reviewed:yes AP1AR], [http://www.uniprot.org/uniprot/?query=gene:WIPI1+AND+taxonomy:9606+AND+reviewed:yes WIPI1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0030050</td><td>vesicle transport along actin filament</td><td>[http://www.uniprot.org/uniprot/?query=gene:FNBP1L+AND+taxonomy:9606+AND+reviewed:yes FNBP1L], [http://www.uniprot.org/uniprot/?query=gene:WASL+AND+taxonomy:9606+AND+reviewed:yes WASL]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0031022</td><td>nuclear migration along microfilament</td><td>[http://www.uniprot.org/uniprot/?query=gene:SYNE2+AND+taxonomy:9606+AND+reviewed:yes SYNE2], [http://www.uniprot.org/uniprot/?query=gene:SUN2+AND+taxonomy:9606+AND+reviewed:yes SUN2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070358</td><td>actin polymerization-dependent cell motility</td><td>[http://www.uniprot.org/uniprot/?query=gene:JMY+AND+taxonomy:9606+AND+reviewed:yes JMY], [http://www.uniprot.org/uniprot/?query=gene:NCKAP1L+AND+taxonomy:9606+AND+reviewed:yes NCKAP1L], [http://www.uniprot.org/uniprot/?query=gene:EPS8+AND+taxonomy:9606+AND+reviewed:yes EPS8]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0097491</td><td>sympathetic neuron projection guidance</td><td>[http://www.uniprot.org/uniprot/?query=gene:NRP1+AND+taxonomy:9606+AND+reviewed:yes NRP1], [http://www.uniprot.org/uniprot/?query=gene:NRP2+AND+taxonomy:9606+AND+reviewed:yes NRP2], [http://www.uniprot.org/uniprot/?query=gene:SEMA3A+AND+taxonomy:9606+AND+reviewed:yes SEMA3A], [http://www.uniprot.org/uniprot/?query=gene:SEMA3F+AND+taxonomy:9606+AND+reviewed:yes SEMA3F]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0006949</td><td>syncytium formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ERCC1+AND+taxonomy:9606+AND+reviewed:yes ERCC1], [http://www.uniprot.org/uniprot/?query=gene:CCNG1+AND+taxonomy:9606+AND+reviewed:yes CCNG1], [http://www.uniprot.org/uniprot/?query=gene:ERVW-1+AND+taxonomy:9606+AND+reviewed:yes ERVW-1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006999</td><td>nuclear pore organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:NUP98+AND+taxonomy:9606+AND+reviewed:yes NUP98], [http://www.uniprot.org/uniprot/?query=gene:SEH1L+AND+taxonomy:9606+AND+reviewed:yes SEH1L], [http://www.uniprot.org/uniprot/?query=gene:NUP133+AND+taxonomy:9606+AND+reviewed:yes NUP133], [http://www.uniprot.org/uniprot/?query=gene:TPR+AND+taxonomy:9606+AND+reviewed:yes TPR]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0007000</td><td>nucleolus organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOLC1+AND+taxonomy:9606+AND+reviewed:yes NOLC1], [http://www.uniprot.org/uniprot/?query=gene:RRN3+AND+taxonomy:9606+AND+reviewed:yes RRN3], [http://www.uniprot.org/uniprot/?query=gene:RPS19+AND+taxonomy:9606+AND+reviewed:yes RPS19], [http://www.uniprot.org/uniprot/?query=gene:PES1+AND+taxonomy:9606+AND+reviewed:yes PES1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0007290</td><td>spermatid nucleus elongation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TNP1+AND+taxonomy:9606+AND+reviewed:yes TNP1], [http://www.uniprot.org/uniprot/?query=gene:H1FNT+AND+taxonomy:9606+AND+reviewed:yes H1FNT], [http://www.uniprot.org/uniprot/?query=gene:KDM3A+AND+taxonomy:9606+AND+reviewed:yes KDM3A]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0030382</td><td>sperm mitochondrion organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:PVRL2+AND+taxonomy:9606+AND+reviewed:yes PVRL2], [http://www.uniprot.org/uniprot/?query=gene:SEPT4+AND+taxonomy:9606+AND+reviewed:yes SEPT4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0090161</td><td>Golgi ribbon formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:OPTN+AND+taxonomy:9606+AND+reviewed:yes OPTN], [http://www.uniprot.org/uniprot/?query=gene:TMED5+AND+taxonomy:9606+AND+reviewed:yes TMED5], [http://www.uniprot.org/uniprot/?query=gene:GCC2+AND+taxonomy:9606+AND+reviewed:yes GCC2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0090166</td><td>Golgi disassembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:PLK3+AND+taxonomy:9606+AND+reviewed:yes PLK3], [http://www.uniprot.org/uniprot/?query=gene:VRK1+AND+taxonomy:9606+AND+reviewed:yes VRK1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0007033</td><td>vacuole organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAN2A1+AND+taxonomy:9606+AND+reviewed:yes MAN2A1], [http://www.uniprot.org/uniprot/?query=gene:FIG4+AND+taxonomy:9606+AND+reviewed:yes FIG4], [http://www.uniprot.org/uniprot/?query=gene:NDP+AND+taxonomy:9606+AND+reviewed:yes NDP]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0006900</td><td>membrane budding</td><td>[http://www.uniprot.org/uniprot/?query=gene:P2RX7+AND+taxonomy:9606+AND+reviewed:yes P2RX7], [http://www.uniprot.org/uniprot/?query=gene:FNBP1L+AND+taxonomy:9606+AND+reviewed:yes FNBP1L], [http://www.uniprot.org/uniprot/?query=gene:WASL+AND+taxonomy:9606+AND+reviewed:yes WASL]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0030719</td><td>P granule organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:PLD6+AND+taxonomy:9606+AND+reviewed:yes PLD6], [http://www.uniprot.org/uniprot/?query=gene:TDRD5+AND+taxonomy:9606+AND+reviewed:yes TDRD5]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0031023</td><td>microtubule organizing center organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:PAFAH1B1+AND+taxonomy:9606+AND+reviewed:yes PAFAH1B1], [http://www.uniprot.org/uniprot/?query=gene:CLASP2+AND+taxonomy:9606+AND+reviewed:yes CLASP2], [http://www.uniprot.org/uniprot/?query=gene:CLASP1+AND+taxonomy:9606+AND+reviewed:yes CLASP1], [http://www.uniprot.org/uniprot/?query=gene:GCC2+AND+taxonomy:9606+AND+reviewed:yes GCC2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0000715</td><td>nucleotide-excision repair, DNA damage recognition</td><td>[http://www.uniprot.org/uniprot/?query=gene:XPC+AND+taxonomy:9606+AND+reviewed:yes XPC], [http://www.uniprot.org/uniprot/?query=gene:RAD23B+AND+taxonomy:9606+AND+reviewed:yes RAD23B]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0000819</td><td>sister chromatid segregation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TOP2B+AND+taxonomy:9606+AND+reviewed:yes TOP2B], [http://www.uniprot.org/uniprot/?query=gene:TOP2A+AND+taxonomy:9606+AND+reviewed:yes TOP2A], [http://www.uniprot.org/uniprot/?query=gene:LATS1+AND+taxonomy:9606+AND+reviewed:yes LATS1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006344</td><td>maintenance of chromatin silencing</td><td>[http://www.uniprot.org/uniprot/?query=gene:HDAC2+AND+taxonomy:9606+AND+reviewed:yes HDAC2], [http://www.uniprot.org/uniprot/?query=gene:UBE2B+AND+taxonomy:9606+AND+reviewed:yes UBE2B], [http://www.uniprot.org/uniprot/?query=gene:SIRT1+AND+taxonomy:9606+AND+reviewed:yes SIRT1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0000022</td><td>mitotic spindle elongation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PRC1+AND+taxonomy:9606+AND+reviewed:yes PRC1], [http://www.uniprot.org/uniprot/?query=gene:KIF23+AND+taxonomy:9606+AND+reviewed:yes KIF23]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0098535</td><td>de novo centriole assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:CCDC78+AND+taxonomy:9606+AND+reviewed:yes CCDC78], [http://www.uniprot.org/uniprot/?query=gene:PLK4+AND+taxonomy:9606+AND+reviewed:yes PLK4], [http://www.uniprot.org/uniprot/?query=gene:CEP152+AND+taxonomy:9606+AND+reviewed:yes CEP152], [http://www.uniprot.org/uniprot/?query=gene:CCDC67+AND+taxonomy:9606+AND+reviewed:yes CCDC67]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0007028</td><td>cytoplasm organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:TFCP2L1+AND+taxonomy:9606+AND+reviewed:yes TFCP2L1], [http://www.uniprot.org/uniprot/?query=gene:RRN3+AND+taxonomy:9606+AND+reviewed:yes RRN3], [http://www.uniprot.org/uniprot/?query=gene:KIF5B+AND+taxonomy:9606+AND+reviewed:yes KIF5B]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0007296</td><td>vitellogenesis</td><td>[http://www.uniprot.org/uniprot/?query=gene:ZMIZ1+AND+taxonomy:9606+AND+reviewed:yes ZMIZ1], [http://www.uniprot.org/uniprot/?query=gene:FOSL1+AND+taxonomy:9606+AND+reviewed:yes FOSL1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0007113</td><td>endomitotic cell cycle</td><td>[http://www.uniprot.org/uniprot/?query=gene:UBA3+AND+taxonomy:9606+AND+reviewed:yes UBA3], [http://www.uniprot.org/uniprot/?query=gene:CIB1+AND+taxonomy:9606+AND+reviewed:yes CIB1], [http://www.uniprot.org/uniprot/?query=gene:PLK3+AND+taxonomy:9606+AND+reviewed:yes PLK3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0007060</td><td>male meiosis chromosome segregation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TEX11+AND+taxonomy:9606+AND+reviewed:yes TEX11], [http://www.uniprot.org/uniprot/?query=gene:MLH1+AND+taxonomy:9606+AND+reviewed:yes MLH1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0045143</td><td>homologous chromosome segregation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ESPL1+AND+taxonomy:9606+AND+reviewed:yes ESPL1], [http://www.uniprot.org/uniprot/?query=gene:MSH4+AND+taxonomy:9606+AND+reviewed:yes MSH4], [http://www.uniprot.org/uniprot/?query=gene:MSH5+AND+taxonomy:9606+AND+reviewed:yes MSH5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021937</td><td>cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:LHX5+AND+taxonomy:9606+AND+reviewed:yes LHX5], [http://www.uniprot.org/uniprot/?query=gene:LHX1+AND+taxonomy:9606+AND+reviewed:yes LHX1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0035425</td><td>autocrine signaling</td><td>[http://www.uniprot.org/uniprot/?query=gene:HILPDA+AND+taxonomy:9606+AND+reviewed:yes HILPDA], [http://www.uniprot.org/uniprot/?query=gene:FZD1+AND+taxonomy:9606+AND+reviewed:yes FZD1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0038001</td><td>paracrine signaling</td><td>[http://www.uniprot.org/uniprot/?query=gene:PDGFB+AND+taxonomy:9606+AND+reviewed:yes PDGFB], [http://www.uniprot.org/uniprot/?query=gene:CD34+AND+taxonomy:9606+AND+reviewed:yes CD34]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060638</td><td>mesenchymal-epithelial cell signaling</td><td>[http://www.uniprot.org/uniprot/?query=gene:HOXA5+AND+taxonomy:9606+AND+reviewed:yes HOXA5], [http://www.uniprot.org/uniprot/?query=gene:WNT5A+AND+taxonomy:9606+AND+reviewed:yes WNT5A], [http://www.uniprot.org/uniprot/?query=gene:WNT2B+AND+taxonomy:9606+AND+reviewed:yes WNT2B]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060684</td><td>epithelial-mesenchymal cell signaling</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT6+AND+taxonomy:9606+AND+reviewed:yes WNT6], [http://www.uniprot.org/uniprot/?query=gene:SMO+AND+taxonomy:9606+AND+reviewed:yes SMO], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:CDC42+AND+taxonomy:9606+AND+reviewed:yes CDC42]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0007412</td><td>axon target recognition</td><td>[http://www.uniprot.org/uniprot/?query=gene:UCHL1+AND+taxonomy:9606+AND+reviewed:yes UCHL1], [http://www.uniprot.org/uniprot/?query=gene:BDNF+AND+taxonomy:9606+AND+reviewed:yes BDNF], [http://www.uniprot.org/uniprot/?query=gene:FOXB1+AND+taxonomy:9606+AND+reviewed:yes FOXB1], [http://www.uniprot.org/uniprot/?query=gene:STXBP1+AND+taxonomy:9606+AND+reviewed:yes STXBP1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010643</td><td>cell communication by chemical coupling</td><td>[http://www.uniprot.org/uniprot/?query=gene:DBN1+AND+taxonomy:9606+AND+reviewed:yes DBN1], [http://www.uniprot.org/uniprot/?query=gene:GJA1+AND+taxonomy:9606+AND+reviewed:yes GJA1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0010644</td><td>cell communication by electrical coupling</td><td>[http://www.uniprot.org/uniprot/?query=gene:DBN1+AND+taxonomy:9606+AND+reviewed:yes DBN1], [http://www.uniprot.org/uniprot/?query=gene:GJA1+AND+taxonomy:9606+AND+reviewed:yes GJA1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071460</td><td>cellular response to cell-matrix adhesion</td><td>[http://www.uniprot.org/uniprot/?query=gene:SKP2+AND+taxonomy:9606+AND+reviewed:yes SKP2], [http://www.uniprot.org/uniprot/?query=gene:DSPP+AND+taxonomy:9606+AND+reviewed:yes DSPP]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0035426</td><td>extracellular matrix-cell signaling</td><td>[http://www.uniprot.org/uniprot/?query=gene:FZD4+AND+taxonomy:9606+AND+reviewed:yes FZD4], [http://www.uniprot.org/uniprot/?query=gene:FER+AND+taxonomy:9606+AND+reviewed:yes FER], [http://www.uniprot.org/uniprot/?query=gene:NDP+AND+taxonomy:9606+AND+reviewed:yes NDP]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0086067</td><td>AV node cell to bundle of His cell communication</td><td>[http://www.uniprot.org/uniprot/?query=gene:CXADR+AND+taxonomy:9606+AND+reviewed:yes CXADR], [http://www.uniprot.org/uniprot/?query=gene:SCN10A+AND+taxonomy:9606+AND+reviewed:yes SCN10A], [http://www.uniprot.org/uniprot/?query=gene:SCN5A+AND+taxonomy:9606+AND+reviewed:yes SCN5A], [http://www.uniprot.org/uniprot/?query=gene:SCN4B+AND+taxonomy:9606+AND+reviewed:yes SCN4B]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0086070</td><td>SA node cell to atrial cardiac muscle cell communication</td><td>[http://www.uniprot.org/uniprot/?query=gene:SCN3B+AND+taxonomy:9606+AND+reviewed:yes SCN3B], [http://www.uniprot.org/uniprot/?query=gene:ANK2+AND+taxonomy:9606+AND+reviewed:yes ANK2], [http://www.uniprot.org/uniprot/?query=gene:SCN5A+AND+taxonomy:9606+AND+reviewed:yes SCN5A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006931</td><td>substrate-dependent cell migration, cell attachment to substrate</td><td>[http://www.uniprot.org/uniprot/?query=gene:EPB41L5+AND+taxonomy:9606+AND+reviewed:yes EPB41L5], [http://www.uniprot.org/uniprot/?query=gene:TNFRSF12A+AND+taxonomy:9606+AND+reviewed:yes TNFRSF12A], [http://www.uniprot.org/uniprot/?query=gene:CUZD1+AND+taxonomy:9606+AND+reviewed:yes CUZD1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0003365</td><td>establishment of cell polarity involved in ameboidal cell migration</td><td>[http://www.uniprot.org/uniprot/?query=gene:AMOTL1+AND+taxonomy:9606+AND+reviewed:yes AMOTL1], [http://www.uniprot.org/uniprot/?query=gene:AMOT+AND+taxonomy:9606+AND+reviewed:yes AMOT]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0045200</td><td>establishment of neuroblast polarity</td><td>[http://www.uniprot.org/uniprot/?query=gene:DOCK7+AND+taxonomy:9606+AND+reviewed:yes DOCK7], [http://www.uniprot.org/uniprot/?query=gene:FGF13+AND+taxonomy:9606+AND+reviewed:yes FGF13], [http://www.uniprot.org/uniprot/?query=gene:RAB10+AND+taxonomy:9606+AND+reviewed:yes RAB10]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0030011</td><td>maintenance of cell polarity</td><td>[http://www.uniprot.org/uniprot/?query=gene:DST+AND+taxonomy:9606+AND+reviewed:yes DST], [http://www.uniprot.org/uniprot/?query=gene:NCKAP1L+AND+taxonomy:9606+AND+reviewed:yes NCKAP1L], [http://www.uniprot.org/uniprot/?query=gene:ATN1+AND+taxonomy:9606+AND+reviewed:yes ATN1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0001300</td><td>chronological cell aging</td><td>[http://www.uniprot.org/uniprot/?query=gene:ENG+AND+taxonomy:9606+AND+reviewed:yes ENG], [http://www.uniprot.org/uniprot/?query=gene:SERPINE1+AND+taxonomy:9606+AND+reviewed:yes SERPINE1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001302</td><td>replicative cell aging</td><td>[http://www.uniprot.org/uniprot/?query=gene:ERCC1+AND+taxonomy:9606+AND+reviewed:yes ERCC1], [http://www.uniprot.org/uniprot/?query=gene:WRN+AND+taxonomy:9606+AND+reviewed:yes WRN], [http://www.uniprot.org/uniprot/?query=gene:ROMO1+AND+taxonomy:9606+AND+reviewed:yes ROMO1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0043654</td><td>recognition of apoptotic cell</td><td>[http://www.uniprot.org/uniprot/?query=gene:JMJD6+AND+taxonomy:9606+AND+reviewed:yes JMJD6], [http://www.uniprot.org/uniprot/?query=gene:PEAR1+AND+taxonomy:9606+AND+reviewed:yes PEAR1], [http://www.uniprot.org/uniprot/?query=gene:SCARB1+AND+taxonomy:9606+AND+reviewed:yes SCARB1], [http://www.uniprot.org/uniprot/?query=gene:MEGF10+AND+taxonomy:9606+AND+reviewed:yes MEGF10]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0016198</td><td>axon choice point recognition</td><td>[http://www.uniprot.org/uniprot/?query=gene:GAP43+AND+taxonomy:9606+AND+reviewed:yes GAP43], [http://www.uniprot.org/uniprot/?query=gene:EFNB3+AND+taxonomy:9606+AND+reviewed:yes EFNB3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070593</td><td>dendrite self-avoidance</td><td>[http://www.uniprot.org/uniprot/?query=gene:DSCAM+AND+taxonomy:9606+AND+reviewed:yes DSCAM], [http://www.uniprot.org/uniprot/?query=gene:DSCAML1+AND+taxonomy:9606+AND+reviewed:yes DSCAML1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0009988</td><td>cell-cell recognition</td><td>[http://www.uniprot.org/uniprot/?query=gene:CLEC4M+AND+taxonomy:9606+AND+reviewed:yes CLEC4M], [http://www.uniprot.org/uniprot/?query=gene:FUT3+AND+taxonomy:9606+AND+reviewed:yes FUT3], [http://www.uniprot.org/uniprot/?query=gene:CD209+AND+taxonomy:9606+AND+reviewed:yes CD209], [http://www.uniprot.org/uniprot/?query=gene:ST6GALNAC6+AND+taxonomy:9606+AND+reviewed:yes ST6GALNAC6]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0001771</td><td>immunological synapse formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:DOCK2+AND+taxonomy:9606+AND+reviewed:yes DOCK2], [http://www.uniprot.org/uniprot/?query=gene:CCL19+AND+taxonomy:9606+AND+reviewed:yes CCL19], [http://www.uniprot.org/uniprot/?query=gene:CCL21+AND+taxonomy:9606+AND+reviewed:yes CCL21], [http://www.uniprot.org/uniprot/?query=gene:DLG1+AND+taxonomy:9606+AND+reviewed:yes DLG1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070269</td><td>pyroptosis</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLRC4+AND+taxonomy:9606+AND+reviewed:yes NLRC4], [http://www.uniprot.org/uniprot/?query=gene:AIM2+AND+taxonomy:9606+AND+reviewed:yes AIM2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0001555</td><td>oocyte growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:KMT2D+AND+taxonomy:9606+AND+reviewed:yes KMT2D], [http://www.uniprot.org/uniprot/?query=gene:GDF9+AND+taxonomy:9606+AND+reviewed:yes GDF9]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070050</td><td>neuron cellular homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:CHRNA1+AND+taxonomy:9606+AND+reviewed:yes CHRNA1], [http://www.uniprot.org/uniprot/?query=gene:TYRO3+AND+taxonomy:9606+AND+reviewed:yes TYRO3], [http://www.uniprot.org/uniprot/?query=gene:HAAO+AND+taxonomy:9606+AND+reviewed:yes HAAO], [http://www.uniprot.org/uniprot/?query=gene:FGGY+AND+taxonomy:9606+AND+reviewed:yes FGGY]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0031577</td><td>spindle checkpoint</td><td>[http://www.uniprot.org/uniprot/?query=gene:SPDL1+AND+taxonomy:9606+AND+reviewed:yes SPDL1], [http://www.uniprot.org/uniprot/?query=gene:BIRC5+AND+taxonomy:9606+AND+reviewed:yes BIRC5], [http://www.uniprot.org/uniprot/?query=gene:TAOK1+AND+taxonomy:9606+AND+reviewed:yes TAOK1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0000320</td><td>re-entry into mitotic cell cycle</td><td>[http://www.uniprot.org/uniprot/?query=gene:GSK3B+AND+taxonomy:9606+AND+reviewed:yes GSK3B], [http://www.uniprot.org/uniprot/?query=gene:CCNF+AND+taxonomy:9606+AND+reviewed:yes CCNF], [http://www.uniprot.org/uniprot/?query=gene:CCND1+AND+taxonomy:9606+AND+reviewed:yes CCND1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0033206</td><td>meiotic cytokinesis</td><td>[http://www.uniprot.org/uniprot/?query=gene:ACTR3+AND+taxonomy:9606+AND+reviewed:yes ACTR3], [http://www.uniprot.org/uniprot/?query=gene:ACTR2+AND+taxonomy:9606+AND+reviewed:yes ACTR2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0007127</td><td>meiosis I</td><td>[http://www.uniprot.org/uniprot/?query=gene:PSMD13+AND+taxonomy:9606+AND+reviewed:yes PSMD13], [http://www.uniprot.org/uniprot/?query=gene:CKS2+AND+taxonomy:9606+AND+reviewed:yes CKS2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051322</td><td>anaphase</td><td>[http://www.uniprot.org/uniprot/?query=gene:CUL3+AND+taxonomy:9606+AND+reviewed:yes CUL3], [http://www.uniprot.org/uniprot/?query=gene:USP44+AND+taxonomy:9606+AND+reviewed:yes USP44]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0007109</td><td>cytokinesis, completion of separation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SPAST+AND+taxonomy:9606+AND+reviewed:yes SPAST], [http://www.uniprot.org/uniprot/?query=gene:ANXA11+AND+taxonomy:9606+AND+reviewed:yes ANXA11]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0034088</td><td>maintenance of mitotic sister chromatid cohesion</td><td>[http://www.uniprot.org/uniprot/?query=gene:NIPBL+AND+taxonomy:9606+AND+reviewed:yes NIPBL], [http://www.uniprot.org/uniprot/?query=gene:DSCC1+AND+taxonomy:9606+AND+reviewed:yes DSCC1], [http://www.uniprot.org/uniprot/?query=gene:RB1+AND+taxonomy:9606+AND+reviewed:yes RB1], [http://www.uniprot.org/uniprot/?query=gene:MAU2+AND+taxonomy:9606+AND+reviewed:yes MAU2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0044770</td><td>cell cycle phase transition</td><td>[http://www.uniprot.org/uniprot/?query=gene:TIPIN+AND+taxonomy:9606+AND+reviewed:yes TIPIN], [http://www.uniprot.org/uniprot/?query=gene:TIMELESS+AND+taxonomy:9606+AND+reviewed:yes TIMELESS], [http://www.uniprot.org/uniprot/?query=gene:CDC7+AND+taxonomy:9606+AND+reviewed:yes CDC7], [http://www.uniprot.org/uniprot/?query=gene:PTPRC+AND+taxonomy:9606+AND+reviewed:yes PTPRC]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0045023</td><td>G0 to G1 transition</td><td>[http://www.uniprot.org/uniprot/?query=gene:MDM4+AND+taxonomy:9606+AND+reviewed:yes MDM4], [http://www.uniprot.org/uniprot/?query=gene:CDK3+AND+taxonomy:9606+AND+reviewed:yes CDK3]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0051304</td><td>chromosome separation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SMARCAD1+AND+taxonomy:9606+AND+reviewed:yes SMARCAD1], [http://www.uniprot.org/uniprot/?query=gene:RECQL5+AND+taxonomy:9606+AND+reviewed:yes RECQL5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051306</td><td>mitotic sister chromatid separation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TEX14+AND+taxonomy:9606+AND+reviewed:yes TEX14], [http://www.uniprot.org/uniprot/?query=gene:DIS3L2+AND+taxonomy:9606+AND+reviewed:yes DIS3L2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0051653</td><td>spindle localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:ACTR3+AND+taxonomy:9606+AND+reviewed:yes ACTR3], [http://www.uniprot.org/uniprot/?query=gene:ACTR2+AND+taxonomy:9606+AND+reviewed:yes ACTR2], [http://www.uniprot.org/uniprot/?query=gene:WASL+AND+taxonomy:9606+AND+reviewed:yes WASL]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0070314</td><td>G1 to G0 transition</td><td>[http://www.uniprot.org/uniprot/?query=gene:EZH2+AND+taxonomy:9606+AND+reviewed:yes EZH2], [http://www.uniprot.org/uniprot/?query=gene:CYP27B1+AND+taxonomy:9606+AND+reviewed:yes CYP27B1], [http://www.uniprot.org/uniprot/?query=gene:C2orf40+AND+taxonomy:9606+AND+reviewed:yes C2orf40]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070315</td><td>G1 to G0 transition involved in cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC39A5+AND+taxonomy:9606+AND+reviewed:yes SLC39A5], [http://www.uniprot.org/uniprot/?query=gene:CAPN3+AND+taxonomy:9606+AND+reviewed:yes CAPN3]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0048278</td><td>vesicle docking</td><td>[http://www.uniprot.org/uniprot/?query=gene:EXOC5+AND+taxonomy:9606+AND+reviewed:yes EXOC5], [http://www.uniprot.org/uniprot/?query=gene:CAV2+AND+taxonomy:9606+AND+reviewed:yes CAV2], [http://www.uniprot.org/uniprot/?query=gene:CCDC41+AND+taxonomy:9606+AND+reviewed:yes CCDC41]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0043241</td><td>protein complex disassembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:DDIT4+AND+taxonomy:9606+AND+reviewed:yes DDIT4], [http://www.uniprot.org/uniprot/?query=gene:HDAC6+AND+taxonomy:9606+AND+reviewed:yes HDAC6]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0030029</td><td>actin filament-based process</td><td>[http://www.uniprot.org/uniprot/?query=gene:ELMO1+AND+taxonomy:9606+AND+reviewed:yes ELMO1], [http://www.uniprot.org/uniprot/?query=gene:SELE+AND+taxonomy:9606+AND+reviewed:yes SELE]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0006930</td><td>substrate-dependent cell migration, cell extension</td><td>[http://www.uniprot.org/uniprot/?query=gene:OPHN1+AND+taxonomy:9606+AND+reviewed:yes OPHN1], [http://www.uniprot.org/uniprot/?query=gene:SDCBP+AND+taxonomy:9606+AND+reviewed:yes SDCBP], [http://www.uniprot.org/uniprot/?query=gene:MYH10+AND+taxonomy:9606+AND+reviewed:yes MYH10], [http://www.uniprot.org/uniprot/?query=gene:CD2AP+AND+taxonomy:9606+AND+reviewed:yes CD2AP]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0030035</td><td>microspike assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:ACTN2+AND+taxonomy:9606+AND+reviewed:yes ACTN2], [http://www.uniprot.org/uniprot/?query=gene:FGD4+AND+taxonomy:9606+AND+reviewed:yes FGD4], [http://www.uniprot.org/uniprot/?query=gene:MTSS1+AND+taxonomy:9606+AND+reviewed:yes MTSS1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0032796</td><td>uropod organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:CORO1A+AND+taxonomy:9606+AND+reviewed:yes CORO1A], [http://www.uniprot.org/uniprot/?query=gene:MYH9+AND+taxonomy:9606+AND+reviewed:yes MYH9]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0044375</td><td>regulation of peroxisome size</td><td>[http://www.uniprot.org/uniprot/?query=gene:PEX11G+AND+taxonomy:9606+AND+reviewed:yes PEX11G], [http://www.uniprot.org/uniprot/?query=gene:PEX11A+AND+taxonomy:9606+AND+reviewed:yes PEX11A], [http://www.uniprot.org/uniprot/?query=gene:PEX11B+AND+taxonomy:9606+AND+reviewed:yes PEX11B]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0043482</td><td>cellular pigment accumulation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SHROOM3+AND+taxonomy:9606+AND+reviewed:yes SHROOM3], [http://www.uniprot.org/uniprot/?query=gene:SHROOM2+AND+taxonomy:9606+AND+reviewed:yes SHROOM2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0002934</td><td>desmosome organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:DSP+AND+taxonomy:9606+AND+reviewed:yes DSP], [http://www.uniprot.org/uniprot/?query=gene:PERP+AND+taxonomy:9606+AND+reviewed:yes PERP], [http://www.uniprot.org/uniprot/?query=gene:PVRL1+AND+taxonomy:9606+AND+reviewed:yes PVRL1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0035845</td><td>photoreceptor cell outer segment organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:AHI1+AND+taxonomy:9606+AND+reviewed:yes AHI1], [http://www.uniprot.org/uniprot/?query=gene:RP1+AND+taxonomy:9606+AND+reviewed:yes RP1], [http://www.uniprot.org/uniprot/?query=gene:TOPORS+AND+taxonomy:9606+AND+reviewed:yes TOPORS], [http://www.uniprot.org/uniprot/?query=gene:NPHP1+AND+taxonomy:9606+AND+reviewed:yes NPHP1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071711</td><td>basement membrane organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:FSHR+AND+taxonomy:9606+AND+reviewed:yes FSHR], [http://www.uniprot.org/uniprot/?query=gene:RIC8A+AND+taxonomy:9606+AND+reviewed:yes RIC8A], [http://www.uniprot.org/uniprot/?query=gene:TFAP2A+AND+taxonomy:9606+AND+reviewed:yes TFAP2A]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0097062</td><td>dendritic spine maintenance</td><td>[http://www.uniprot.org/uniprot/?query=gene:PICK1+AND+taxonomy:9606+AND+reviewed:yes PICK1], [http://www.uniprot.org/uniprot/?query=gene:TANC1+AND+taxonomy:9606+AND+reviewed:yes TANC1], [http://www.uniprot.org/uniprot/?query=gene:MTMR2+AND+taxonomy:9606+AND+reviewed:yes MTMR2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0007501</td><td>mesodermal cell fate specification</td><td>[http://www.uniprot.org/uniprot/?query=gene:HOXA11+AND+taxonomy:9606+AND+reviewed:yes HOXA11], [http://www.uniprot.org/uniprot/?query=gene:EYA2+AND+taxonomy:9606+AND+reviewed:yes EYA2], [http://www.uniprot.org/uniprot/?query=gene:PAX2+AND+taxonomy:9606+AND+reviewed:yes PAX2], [http://www.uniprot.org/uniprot/?query=gene:SIX2+AND+taxonomy:9606+AND+reviewed:yes SIX2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0048866</td><td>stem cell fate specification</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOX18+AND+taxonomy:9606+AND+reviewed:yes SOX18], [http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0007403</td><td>glial cell fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:NTF3+AND+taxonomy:9606+AND+reviewed:yes NTF3], [http://www.uniprot.org/uniprot/?query=gene:CTNNB1+AND+taxonomy:9606+AND+reviewed:yes CTNNB1], [http://www.uniprot.org/uniprot/?query=gene:SMARCA4+AND+taxonomy:9606+AND+reviewed:yes SMARCA4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0007493</td><td>endodermal cell fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17], [http://www.uniprot.org/uniprot/?query=gene:GATA6+AND+taxonomy:9606+AND+reviewed:yes GATA6]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0007500</td><td>mesodermal cell fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:KLF4+AND+taxonomy:9606+AND+reviewed:yes KLF4], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:TRIM15+AND+taxonomy:9606+AND+reviewed:yes TRIM15], [http://www.uniprot.org/uniprot/?query=gene:TDGF1P3+AND+taxonomy:9606+AND+reviewed:yes TDGF1P3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0007518</td><td>myoblast fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:IFRD1+AND+taxonomy:9606+AND+reviewed:yes IFRD1], [http://www.uniprot.org/uniprot/?query=gene:MYOD1+AND+taxonomy:9606+AND+reviewed:yes MYOD1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0007521</td><td>muscle cell fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:TBX2+AND+taxonomy:9606+AND+reviewed:yes TBX2], [http://www.uniprot.org/uniprot/?query=gene:MEF2C+AND+taxonomy:9606+AND+reviewed:yes MEF2C], [http://www.uniprot.org/uniprot/?query=gene:MEF2A+AND+taxonomy:9606+AND+reviewed:yes MEF2A]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0048664</td><td>neuron fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT1+AND+taxonomy:9606+AND+reviewed:yes WNT1], [http://www.uniprot.org/uniprot/?query=gene:LBX1+AND+taxonomy:9606+AND+reviewed:yes LBX1], [http://www.uniprot.org/uniprot/?query=gene:CDC42+AND+taxonomy:9606+AND+reviewed:yes CDC42]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060913</td><td>cardiac cell fate determination</td><td>[http://www.uniprot.org/uniprot/?query=gene:MESP1+AND+taxonomy:9606+AND+reviewed:yes MESP1], [http://www.uniprot.org/uniprot/?query=gene:ISL1+AND+taxonomy:9606+AND+reviewed:yes ISL1], [http://www.uniprot.org/uniprot/?query=gene:POU5F1+AND+taxonomy:9606+AND+reviewed:yes POU5F1], [http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001826</td><td>inner cell mass cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLE1+AND+taxonomy:9606+AND+reviewed:yes NLE1], [http://www.uniprot.org/uniprot/?query=gene:TET1+AND+taxonomy:9606+AND+reviewed:yes TET1], [http://www.uniprot.org/uniprot/?query=gene:HNF1B+AND+taxonomy:9606+AND+reviewed:yes HNF1B]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009994</td><td>oocyte differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:KMT2B+AND+taxonomy:9606+AND+reviewed:yes KMT2B], [http://www.uniprot.org/uniprot/?query=gene:NPM2+AND+taxonomy:9606+AND+reviewed:yes NPM2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010668</td><td>ectodermal cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ERF+AND+taxonomy:9606+AND+reviewed:yes ERF], [http://www.uniprot.org/uniprot/?query=gene:VPS52+AND+taxonomy:9606+AND+reviewed:yes VPS52]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021533</td><td>cell differentiation in hindbrain</td><td>[http://www.uniprot.org/uniprot/?query=gene:PHOX2B+AND+taxonomy:9606+AND+reviewed:yes PHOX2B], [http://www.uniprot.org/uniprot/?query=gene:NOG+AND+taxonomy:9606+AND+reviewed:yes NOG], [http://www.uniprot.org/uniprot/?query=gene:FOXA2+AND+taxonomy:9606+AND+reviewed:yes FOXA2], [http://www.uniprot.org/uniprot/?query=gene:GATA2+AND+taxonomy:9606+AND+reviewed:yes GATA2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0021979</td><td>hypothalamus cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:OTP+AND+taxonomy:9606+AND+reviewed:yes OTP], [http://www.uniprot.org/uniprot/?query=gene:POU3F2+AND+taxonomy:9606+AND+reviewed:yes POU3F2], [http://www.uniprot.org/uniprot/?query=gene:PROP1+AND+taxonomy:9606+AND+reviewed:yes PROP1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0035987</td><td>endodermal cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NODAL+AND+taxonomy:9606+AND+reviewed:yes NODAL], [http://www.uniprot.org/uniprot/?query=gene:HMGA2+AND+taxonomy:9606+AND+reviewed:yes HMGA2], [http://www.uniprot.org/uniprot/?query=gene:MIXL1+AND+taxonomy:9606+AND+reviewed:yes MIXL1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0035990</td><td>tendon cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TNMD+AND+taxonomy:9606+AND+reviewed:yes TNMD], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:MKX+AND+taxonomy:9606+AND+reviewed:yes MKX], [http://www.uniprot.org/uniprot/?query=gene:SCXA+AND+taxonomy:9606+AND+reviewed:yes SCXA]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0048333</td><td>mesodermal cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:HMGA2+AND+taxonomy:9606+AND+reviewed:yes HMGA2], [http://www.uniprot.org/uniprot/?query=gene:KDM6A+AND+taxonomy:9606+AND+reviewed:yes KDM6A], [http://www.uniprot.org/uniprot/?query=gene:INHBA+AND+taxonomy:9606+AND+reviewed:yes INHBA]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060126</td><td>somatotropin secreting cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT4+AND+taxonomy:9606+AND+reviewed:yes WNT4], [http://www.uniprot.org/uniprot/?query=gene:PITX2+AND+taxonomy:9606+AND+reviewed:yes PITX2], [http://www.uniprot.org/uniprot/?query=gene:PROP1+AND+taxonomy:9606+AND+reviewed:yes PROP1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060128</td><td>corticotropin hormone secreting cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:FGF8+AND+taxonomy:9606+AND+reviewed:yes FGF8], [http://www.uniprot.org/uniprot/?query=gene:FGF2+AND+taxonomy:9606+AND+reviewed:yes FGF2], [http://www.uniprot.org/uniprot/?query=gene:BMP2+AND+taxonomy:9606+AND+reviewed:yes BMP2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060290</td><td>transdifferentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PDX1+AND+taxonomy:9606+AND+reviewed:yes PDX1], [http://www.uniprot.org/uniprot/?query=gene:SMAD3+AND+taxonomy:9606+AND+reviewed:yes SMAD3], [http://www.uniprot.org/uniprot/?query=gene:CD34+AND+taxonomy:9606+AND+reviewed:yes CD34]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060591</td><td>chondroblast differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:RARA+AND+taxonomy:9606+AND+reviewed:yes RARA], [http://www.uniprot.org/uniprot/?query=gene:FGF4+AND+taxonomy:9606+AND+reviewed:yes FGF4], [http://www.uniprot.org/uniprot/?query=gene:FGF2+AND+taxonomy:9606+AND+reviewed:yes FGF2], [http://www.uniprot.org/uniprot/?query=gene:CYR61+AND+taxonomy:9606+AND+reviewed:yes CYR61]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060718</td><td>chorionic trophoblast cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAP3K4+AND+taxonomy:9606+AND+reviewed:yes MAP3K4], [http://www.uniprot.org/uniprot/?query=gene:DNMT3L+AND+taxonomy:9606+AND+reviewed:yes DNMT3L], [http://www.uniprot.org/uniprot/?query=gene:E2F7+AND+taxonomy:9606+AND+reviewed:yes E2F7], [http://www.uniprot.org/uniprot/?query=gene:E2F8+AND+taxonomy:9606+AND+reviewed:yes E2F8]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0003329</td><td>pancreatic PP cell fate commitment</td><td>[http://www.uniprot.org/uniprot/?query=gene:NEUROD1+AND+taxonomy:9606+AND+reviewed:yes NEUROD1], [http://www.uniprot.org/uniprot/?query=gene:NKX2-2+AND+taxonomy:9606+AND+reviewed:yes NKX2-2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0014034</td><td>neural crest cell fate commitment</td><td>[http://www.uniprot.org/uniprot/?query=gene:SFRP1+AND+taxonomy:9606+AND+reviewed:yes SFRP1], [http://www.uniprot.org/uniprot/?query=gene:WNT8A+AND+taxonomy:9606+AND+reviewed:yes WNT8A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021781</td><td>glial cell fate commitment</td><td>[http://www.uniprot.org/uniprot/?query=gene:NRG1+AND+taxonomy:9606+AND+reviewed:yes NRG1], [http://www.uniprot.org/uniprot/?query=gene:HES5+AND+taxonomy:9606+AND+reviewed:yes HES5], [http://www.uniprot.org/uniprot/?query=gene:SOX2+AND+taxonomy:9606+AND+reviewed:yes SOX2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0035854</td><td>eosinophil fate commitment</td><td>[http://www.uniprot.org/uniprot/?query=gene:GATA2+AND+taxonomy:9606+AND+reviewed:yes GATA2], [http://www.uniprot.org/uniprot/?query=gene:GATA1+AND+taxonomy:9606+AND+reviewed:yes GATA1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0048625</td><td>myoblast fate commitment</td><td>[http://www.uniprot.org/uniprot/?query=gene:PITX1+AND+taxonomy:9606+AND+reviewed:yes PITX1], [http://www.uniprot.org/uniprot/?query=gene:TCF7L2+AND+taxonomy:9606+AND+reviewed:yes TCF7L2], [http://www.uniprot.org/uniprot/?query=gene:EPAS1+AND+taxonomy:9606+AND+reviewed:yes EPAS1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0072560</td><td>type B pancreatic cell maturation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NKX6-1+AND+taxonomy:9606+AND+reviewed:yes NKX6-1], [http://www.uniprot.org/uniprot/?query=gene:RFX3+AND+taxonomy:9606+AND+reviewed:yes RFX3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051124</td><td>synaptic growth at neuromuscular junction</td><td>[http://www.uniprot.org/uniprot/?query=gene:LRP4+AND+taxonomy:9606+AND+reviewed:yes LRP4], [http://www.uniprot.org/uniprot/?query=gene:APP+AND+taxonomy:9606+AND+reviewed:yes APP]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0007529</td><td>establishment of synaptic specificity at neuromuscular junction</td><td>[http://www.uniprot.org/uniprot/?query=gene:CHAT+AND+taxonomy:9606+AND+reviewed:yes CHAT], [http://www.uniprot.org/uniprot/?query=gene:GPHN+AND+taxonomy:9606+AND+reviewed:yes GPHN], [http://www.uniprot.org/uniprot/?query=gene:F2R+AND+taxonomy:9606+AND+reviewed:yes F2R]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060074</td><td>synapse maturation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SHANK1+AND+taxonomy:9606+AND+reviewed:yes SHANK1], [http://www.uniprot.org/uniprot/?query=gene:PALM+AND+taxonomy:9606+AND+reviewed:yes PALM], [http://www.uniprot.org/uniprot/?query=gene:PTEN+AND+taxonomy:9606+AND+reviewed:yes PTEN]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0008356</td><td>asymmetric cell division</td><td>[http://www.uniprot.org/uniprot/?query=gene:PARD3+AND+taxonomy:9606+AND+reviewed:yes PARD3], [http://www.uniprot.org/uniprot/?query=gene:ACTR3+AND+taxonomy:9606+AND+reviewed:yes ACTR3], [http://www.uniprot.org/uniprot/?query=gene:ACTR2+AND+taxonomy:9606+AND+reviewed:yes ACTR2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010070</td><td>zygote asymmetric cell division</td><td>[http://www.uniprot.org/uniprot/?query=gene:RGS14+AND+taxonomy:9606+AND+reviewed:yes RGS14], [http://www.uniprot.org/uniprot/?query=gene:DICER1+AND+taxonomy:9606+AND+reviewed:yes DICER1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0021869</td><td>forebrain ventricular zone progenitor cell division</td><td>[http://www.uniprot.org/uniprot/?query=gene:POU3F3+AND+taxonomy:9606+AND+reviewed:yes POU3F3], [http://www.uniprot.org/uniprot/?query=gene:POU3F2+AND+taxonomy:9606+AND+reviewed:yes POU3F2], [http://www.uniprot.org/uniprot/?query=gene:DIXDC1+AND+taxonomy:9606+AND+reviewed:yes DIXDC1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0032418</td><td>lysosome localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:HDAC6+AND+taxonomy:9606+AND+reviewed:yes HDAC6], [http://www.uniprot.org/uniprot/?query=gene:LAMTOR1+AND+taxonomy:9606+AND+reviewed:yes LAMTOR1], [http://www.uniprot.org/uniprot/?query=gene:VPS33B+AND+taxonomy:9606+AND+reviewed:yes VPS33B], [http://www.uniprot.org/uniprot/?query=gene:VPS33A+AND+taxonomy:9606+AND+reviewed:yes VPS33A]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0051646</td><td>mitochondrion localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:MFN2+AND+taxonomy:9606+AND+reviewed:yes MFN2], [http://www.uniprot.org/uniprot/?query=gene:MUL1+AND+taxonomy:9606+AND+reviewed:yes MUL1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051647</td><td>nucleus localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:DMD+AND+taxonomy:9606+AND+reviewed:yes DMD], [http://www.uniprot.org/uniprot/?query=gene:CAV3+AND+taxonomy:9606+AND+reviewed:yes CAV3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0051648</td><td>vesicle localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:TPGS1+AND+taxonomy:9606+AND+reviewed:yes TPGS1], [http://www.uniprot.org/uniprot/?query=gene:MYO1A+AND+taxonomy:9606+AND+reviewed:yes MYO1A]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0051668</td><td>localization within membrane</td><td>[http://www.uniprot.org/uniprot/?query=gene:CDH13+AND+taxonomy:9606+AND+reviewed:yes CDH13], [http://www.uniprot.org/uniprot/?query=gene:RAC1+AND+taxonomy:9606+AND+reviewed:yes RAC1], [http://www.uniprot.org/uniprot/?query=gene:CNIH2+AND+taxonomy:9606+AND+reviewed:yes CNIH2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0008298</td><td>intracellular mRNA localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:CASC3+AND+taxonomy:9606+AND+reviewed:yes CASC3], [http://www.uniprot.org/uniprot/?query=gene:STAU1+AND+taxonomy:9606+AND+reviewed:yes STAU1], [http://www.uniprot.org/uniprot/?query=gene:BICD1+AND+taxonomy:9606+AND+reviewed:yes BICD1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006880</td><td>intracellular sequestering of iron ion</td><td>[http://www.uniprot.org/uniprot/?query=gene:FTH1+AND+taxonomy:9606+AND+reviewed:yes FTH1], [http://www.uniprot.org/uniprot/?query=gene:SRI+AND+taxonomy:9606+AND+reviewed:yes SRI]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0023041</td><td>neuronal signal transduction</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLGN1+AND+taxonomy:9606+AND+reviewed:yes NLGN1], [http://www.uniprot.org/uniprot/?query=gene:P2RY11+AND+taxonomy:9606+AND+reviewed:yes P2RY11], [http://www.uniprot.org/uniprot/?query=gene:NRXN1+AND+taxonomy:9606+AND+reviewed:yes NRXN1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0097527</td><td>necroptotic signaling pathway</td><td>[http://www.uniprot.org/uniprot/?query=gene:RIPK1+AND+taxonomy:9606+AND+reviewed:yes RIPK1], [http://www.uniprot.org/uniprot/?query=gene:TNF+AND+taxonomy:9606+AND+reviewed:yes TNF], [http://www.uniprot.org/uniprot/?query=gene:TLR3+AND+taxonomy:9606+AND+reviewed:yes TLR3], [http://www.uniprot.org/uniprot/?query=gene:FASLG+AND+taxonomy:9606+AND+reviewed:yes FASLG]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070417</td><td>cellular response to cold</td><td>[http://www.uniprot.org/uniprot/?query=gene:FOXO1+AND+taxonomy:9606+AND+reviewed:yes FOXO1], [http://www.uniprot.org/uniprot/?query=gene:NFKBIA+AND+taxonomy:9606+AND+reviewed:yes NFKBIA]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071470</td><td>cellular response to osmotic stress</td><td>[http://www.uniprot.org/uniprot/?query=gene:PKD2+AND+taxonomy:9606+AND+reviewed:yes PKD2], [http://www.uniprot.org/uniprot/?query=gene:TRPV4+AND+taxonomy:9606+AND+reviewed:yes TRPV4], [http://www.uniprot.org/uniprot/?query=gene:DDX3X+AND+taxonomy:9606+AND+reviewed:yes DDX3X], [http://www.uniprot.org/uniprot/?query=gene:SLC2A4+AND+taxonomy:9606+AND+reviewed:yes SLC2A4]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0043503</td><td>skeletal muscle fiber adaptation</td><td>[http://www.uniprot.org/uniprot/?query=gene:MYOD1+AND+taxonomy:9606+AND+reviewed:yes MYOD1], [http://www.uniprot.org/uniprot/?query=gene:ACTA1+AND+taxonomy:9606+AND+reviewed:yes ACTA1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071453</td><td>cellular response to oxygen levels</td><td>[http://www.uniprot.org/uniprot/?query=gene:MYOD1+AND+taxonomy:9606+AND+reviewed:yes MYOD1], [http://www.uniprot.org/uniprot/?query=gene:LPAR1+AND+taxonomy:9606+AND+reviewed:yes LPAR1], [http://www.uniprot.org/uniprot/?query=gene:UCK2+AND+taxonomy:9606+AND+reviewed:yes UCK2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0071467</td><td>cellular response to pH</td><td>[http://www.uniprot.org/uniprot/?query=gene:KCNK18+AND+taxonomy:9606+AND+reviewed:yes KCNK18], [http://www.uniprot.org/uniprot/?query=gene:GPLD1+AND+taxonomy:9606+AND+reviewed:yes GPLD1], [http://www.uniprot.org/uniprot/?query=gene:HYAL1+AND+taxonomy:9606+AND+reviewed:yes HYAL1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071219</td><td>cellular response to molecule of bacterial origin</td><td>[http://www.uniprot.org/uniprot/?query=gene:IRG1+AND+taxonomy:9606+AND+reviewed:yes IRG1], [http://www.uniprot.org/uniprot/?query=gene:FZD5+AND+taxonomy:9606+AND+reviewed:yes FZD5]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0071226</td><td>cellular response to molecule of fungal origin</td><td>[http://www.uniprot.org/uniprot/?query=gene:CLEC7A+AND+taxonomy:9606+AND+reviewed:yes CLEC7A], [http://www.uniprot.org/uniprot/?query=gene:SYK+AND+taxonomy:9606+AND+reviewed:yes SYK]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0060242</td><td>contact inhibition</td><td>[http://www.uniprot.org/uniprot/?query=gene:PTPRJ+AND+taxonomy:9606+AND+reviewed:yes PTPRJ], [http://www.uniprot.org/uniprot/?query=gene:TSPO+AND+taxonomy:9606+AND+reviewed:yes TSPO], [http://www.uniprot.org/uniprot/?query=gene:YAP1+AND+taxonomy:9606+AND+reviewed:yes YAP1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0060352</td><td>cell adhesion molecule production</td><td>[http://www.uniprot.org/uniprot/?query=gene:GCNT1+AND+taxonomy:9606+AND+reviewed:yes GCNT1], [http://www.uniprot.org/uniprot/?query=gene:GOLPH3+AND+taxonomy:9606+AND+reviewed:yes GOLPH3]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0072553</td><td>terminal button organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLGN2+AND+taxonomy:9606+AND+reviewed:yes NLGN2], [http://www.uniprot.org/uniprot/?query=gene:NLGN1+AND+taxonomy:9606+AND+reviewed:yes NLGN1], [http://www.uniprot.org/uniprot/?query=gene:SNAPIN+AND+taxonomy:9606+AND+reviewed:yes SNAPIN]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0097061</td><td>dendritic spine organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:PICK1+AND+taxonomy:9606+AND+reviewed:yes PICK1], [http://www.uniprot.org/uniprot/?query=gene:ARF1+AND+taxonomy:9606+AND+reviewed:yes ARF1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0019043</td><td>establishment of viral latency</td><td>[http://www.uniprot.org/uniprot/?query=gene:CREB3+AND+taxonomy:9606+AND+reviewed:yes CREB3], [http://www.uniprot.org/uniprot/?query=gene:IRF7+AND+taxonomy:9606+AND+reviewed:yes IRF7]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0019046</td><td>release from viral latency</td><td>[http://www.uniprot.org/uniprot/?query=gene:CREB3+AND+taxonomy:9606+AND+reviewed:yes CREB3], [http://www.uniprot.org/uniprot/?query=gene:HCFC1+AND+taxonomy:9606+AND+reviewed:yes HCFC1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0019076</td><td>viral release from host cell</td><td>[http://www.uniprot.org/uniprot/?query=gene:PPID+AND+taxonomy:9606+AND+reviewed:yes PPID], [http://www.uniprot.org/uniprot/?query=gene:PPIA+AND+taxonomy:9606+AND+reviewed:yes PPIA], [http://www.uniprot.org/uniprot/?query=gene:IST1+AND+taxonomy:9606+AND+reviewed:yes IST1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0046755</td><td>viral budding</td><td>[http://www.uniprot.org/uniprot/?query=gene:TSG101+AND+taxonomy:9606+AND+reviewed:yes TSG101], [http://www.uniprot.org/uniprot/?query=gene:LRSAM1+AND+taxonomy:9606+AND+reviewed:yes LRSAM1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0043163</td><td>cell envelope organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:TGM1+AND+taxonomy:9606+AND+reviewed:yes TGM1], [http://www.uniprot.org/uniprot/?query=gene:TGM3+AND+taxonomy:9606+AND+reviewed:yes TGM3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002176</td><td>male germ cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:DMRT1+AND+taxonomy:9606+AND+reviewed:yes DMRT1], [http://www.uniprot.org/uniprot/?query=gene:EIF2S2+AND+taxonomy:9606+AND+reviewed:yes EIF2S2], [http://www.uniprot.org/uniprot/?query=gene:SPINK2+AND+taxonomy:9606+AND+reviewed:yes SPINK2]</td></tr>
 
<tr class="s2"><td>1</td><td>GO:0022414</td><td>reproductive process</td><td>[http://www.uniprot.org/uniprot/?query=gene:ANTXR1+AND+taxonomy:9606+AND+reviewed:yes ANTXR1], [http://www.uniprot.org/uniprot/?query=gene:ANTXR2+AND+taxonomy:9606+AND+reviewed:yes ANTXR2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0001547</td><td>antral ovarian follicle growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:GPR149+AND+taxonomy:9606+AND+reviewed:yes GPR149], [http://www.uniprot.org/uniprot/?query=gene:FOXO3+AND+taxonomy:9606+AND+reviewed:yes FOXO3], [http://www.uniprot.org/uniprot/?query=gene:ESR1+AND+taxonomy:9606+AND+reviewed:yes ESR1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0046661</td><td>male sex differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:DMRT1+AND+taxonomy:9606+AND+reviewed:yes DMRT1], [http://www.uniprot.org/uniprot/?query=gene:FKBP4+AND+taxonomy:9606+AND+reviewed:yes FKBP4]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0022601</td><td>menstrual cycle phase</td><td>[http://www.uniprot.org/uniprot/?query=gene:SFRP1+AND+taxonomy:9606+AND+reviewed:yes SFRP1], [http://www.uniprot.org/uniprot/?query=gene:SFRP4+AND+taxonomy:9606+AND+reviewed:yes SFRP4], [http://www.uniprot.org/uniprot/?query=gene:TGFB2+AND+taxonomy:9606+AND+reviewed:yes TGFB2], [http://www.uniprot.org/uniprot/?query=gene:TGFB3+AND+taxonomy:9606+AND+reviewed:yes TGFB3]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0043084</td><td>penile erection</td><td>[http://www.uniprot.org/uniprot/?query=gene:EDNRA+AND+taxonomy:9606+AND+reviewed:yes EDNRA], [http://www.uniprot.org/uniprot/?query=gene:AVP+AND+taxonomy:9606+AND+reviewed:yes AVP], [http://www.uniprot.org/uniprot/?query=gene:ACVR2A+AND+taxonomy:9606+AND+reviewed:yes ACVR2A], [http://www.uniprot.org/uniprot/?query=gene:AVPR1A+AND+taxonomy:9606+AND+reviewed:yes AVPR1A]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0007320</td><td>insemination</td><td>[http://www.uniprot.org/uniprot/?query=gene:P2RX1+AND+taxonomy:9606+AND+reviewed:yes P2RX1], [http://www.uniprot.org/uniprot/?query=gene:TAC1+AND+taxonomy:9606+AND+reviewed:yes TAC1], [http://www.uniprot.org/uniprot/?query=gene:SEMG1+AND+taxonomy:9606+AND+reviewed:yes SEMG1], [http://www.uniprot.org/uniprot/?query=gene:DDO+AND+taxonomy:9606+AND+reviewed:yes DDO]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0007620</td><td>copulation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ABAT+AND+taxonomy:9606+AND+reviewed:yes ABAT], [http://www.uniprot.org/uniprot/?query=gene:PI3+AND+taxonomy:9606+AND+reviewed:yes PI3]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0051856</td><td>adhesion to symbiont</td><td>[http://www.uniprot.org/uniprot/?query=gene:ICAM1+AND+taxonomy:9606+AND+reviewed:yes ICAM1], [http://www.uniprot.org/uniprot/?query=gene:SCARB1+AND+taxonomy:9606+AND+reviewed:yes SCARB1], [http://www.uniprot.org/uniprot/?query=gene:PVRL2+AND+taxonomy:9606+AND+reviewed:yes PVRL2]</td></tr>
 
<tr class="s2"><td>1</td><td>GO:0023052</td><td>signaling</td><td>[http://www.uniprot.org/uniprot/?query=gene:CCR5+AND+taxonomy:9606+AND+reviewed:yes CCR5], [http://www.uniprot.org/uniprot/?query=gene:CCL3+AND+taxonomy:9606+AND+reviewed:yes CCL3]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0043932</td><td>ossification involved in bone remodeling</td><td>[http://www.uniprot.org/uniprot/?query=gene:TGFB1+AND+taxonomy:9606+AND+reviewed:yes TGFB1], [http://www.uniprot.org/uniprot/?query=gene:TGFB3+AND+taxonomy:9606+AND+reviewed:yes TGFB3], [http://www.uniprot.org/uniprot/?query=gene:CTHRC1+AND+taxonomy:9606+AND+reviewed:yes CTHRC1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010573</td><td>vascular endothelial growth factor production</td><td>[http://www.uniprot.org/uniprot/?query=gene:GPR56+AND+taxonomy:9606+AND+reviewed:yes GPR56], [http://www.uniprot.org/uniprot/?query=gene:HIF1A+AND+taxonomy:9606+AND+reviewed:yes HIF1A]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0032602</td><td>chemokine production</td><td>[http://www.uniprot.org/uniprot/?query=gene:S100A9+AND+taxonomy:9606+AND+reviewed:yes S100A9], [http://www.uniprot.org/uniprot/?query=gene:S100A8+AND+taxonomy:9606+AND+reviewed:yes S100A8]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071954</td><td>chemokine (C-C motif) ligand 11 production</td><td>[http://www.uniprot.org/uniprot/?query=gene:CXCR3+AND+taxonomy:9606+AND+reviewed:yes CXCR3], [http://www.uniprot.org/uniprot/?query=gene:TNFSF4+AND+taxonomy:9606+AND+reviewed:yes TNFSF4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0032608</td><td>interferon-beta production</td><td>[http://www.uniprot.org/uniprot/?query=gene:TMEM173+AND+taxonomy:9606+AND+reviewed:yes TMEM173], [http://www.uniprot.org/uniprot/?query=gene:TRIM56+AND+taxonomy:9606+AND+reviewed:yes TRIM56], [http://www.uniprot.org/uniprot/?query=gene:IRF7+AND+taxonomy:9606+AND+reviewed:yes IRF7]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0032611</td><td>interleukin-1 beta production</td><td>[http://www.uniprot.org/uniprot/?query=gene:IL1B+AND+taxonomy:9606+AND+reviewed:yes IL1B], [http://www.uniprot.org/uniprot/?query=gene:MR1+AND+taxonomy:9606+AND+reviewed:yes MR1], [http://www.uniprot.org/uniprot/?query=gene:PYCARD+AND+taxonomy:9606+AND+reviewed:yes PYCARD], [http://www.uniprot.org/uniprot/?query=gene:CASP1+AND+taxonomy:9606+AND+reviewed:yes CASP1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0032623</td><td>interleukin-2 production</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC11A1+AND+taxonomy:9606+AND+reviewed:yes SLC11A1], [http://www.uniprot.org/uniprot/?query=gene:STOML2+AND+taxonomy:9606+AND+reviewed:yes STOML2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0032633</td><td>interleukin-4 production</td><td>[http://www.uniprot.org/uniprot/?query=gene:TXK+AND+taxonomy:9606+AND+reviewed:yes TXK], [http://www.uniprot.org/uniprot/?query=gene:ITK+AND+taxonomy:9606+AND+reviewed:yes ITK]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0002532</td><td>production of molecular mediator involved in inflammatory response</td><td>[http://www.uniprot.org/uniprot/?query=gene:IL4R+AND+taxonomy:9606+AND+reviewed:yes IL4R], [http://www.uniprot.org/uniprot/?query=gene:CHIA+AND+taxonomy:9606+AND+reviewed:yes CHIA]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002537</td><td>nitric oxide production involved in inflammatory response</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC7A2+AND+taxonomy:9606+AND+reviewed:yes SLC7A2], [http://www.uniprot.org/uniprot/?query=gene:TLR4+AND+taxonomy:9606+AND+reviewed:yes TLR4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002540</td><td>leukotriene production involved in inflammatory response</td><td>[http://www.uniprot.org/uniprot/?query=gene:ALOX5AP+AND+taxonomy:9606+AND+reviewed:yes ALOX5AP], [http://www.uniprot.org/uniprot/?query=gene:ALOX5+AND+taxonomy:9606+AND+reviewed:yes ALOX5]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0003012</td><td>muscle system process</td><td>[http://www.uniprot.org/uniprot/?query=gene:TRIM72+AND+taxonomy:9606+AND+reviewed:yes TRIM72], [http://www.uniprot.org/uniprot/?query=gene:SCO2+AND+taxonomy:9606+AND+reviewed:yes SCO2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060073</td><td>micturition</td><td>[http://www.uniprot.org/uniprot/?query=gene:KCNMA1+AND+taxonomy:9606+AND+reviewed:yes KCNMA1], [http://www.uniprot.org/uniprot/?query=gene:ADRA1A+AND+taxonomy:9606+AND+reviewed:yes ADRA1A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070293</td><td>renal absorption</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC9A3R1+AND+taxonomy:9606+AND+reviewed:yes SLC9A3R1], [http://www.uniprot.org/uniprot/?query=gene:HBB+AND+taxonomy:9606+AND+reviewed:yes HBB], [http://www.uniprot.org/uniprot/?query=gene:AKR1C3+AND+taxonomy:9606+AND+reviewed:yes AKR1C3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001976</td><td>neurological system process involved in regulation of systemic arterial blood pressure</td><td>[http://www.uniprot.org/uniprot/?query=gene:DRD2+AND+taxonomy:9606+AND+reviewed:yes DRD2], [http://www.uniprot.org/uniprot/?query=gene:MECP2+AND+taxonomy:9606+AND+reviewed:yes MECP2], [http://www.uniprot.org/uniprot/?query=gene:CALCA+AND+taxonomy:9606+AND+reviewed:yes CALCA]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010159</td><td>specification of organ position</td><td>[http://www.uniprot.org/uniprot/?query=gene:HOXA3+AND+taxonomy:9606+AND+reviewed:yes HOXA3], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:FOXH1+AND+taxonomy:9606+AND+reviewed:yes FOXH1], [http://www.uniprot.org/uniprot/?query=gene:TBX3+AND+taxonomy:9606+AND+reviewed:yes TBX3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0021532</td><td>neural tube patterning</td><td>[http://www.uniprot.org/uniprot/?query=gene:PTCH1+AND+taxonomy:9606+AND+reviewed:yes PTCH1], [http://www.uniprot.org/uniprot/?query=gene:RPGRIP1L+AND+taxonomy:9606+AND+reviewed:yes RPGRIP1L], [http://www.uniprot.org/uniprot/?query=gene:TMEM107+AND+taxonomy:9606+AND+reviewed:yes TMEM107]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021796</td><td>cerebral cortex regionalization</td><td>[http://www.uniprot.org/uniprot/?query=gene:EMX2+AND+taxonomy:9606+AND+reviewed:yes EMX2], [http://www.uniprot.org/uniprot/?query=gene:EMX1+AND+taxonomy:9606+AND+reviewed:yes EMX1], [http://www.uniprot.org/uniprot/?query=gene:PAX6+AND+taxonomy:9606+AND+reviewed:yes PAX6]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0021871</td><td>forebrain regionalization</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT7B+AND+taxonomy:9606+AND+reviewed:yes WNT7B], [http://www.uniprot.org/uniprot/?query=gene:LHX1+AND+taxonomy:9606+AND+reviewed:yes LHX1], [http://www.uniprot.org/uniprot/?query=gene:PGAP1+AND+taxonomy:9606+AND+reviewed:yes PGAP1], [http://www.uniprot.org/uniprot/?query=gene:WNT2B+AND+taxonomy:9606+AND+reviewed:yes WNT2B]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021978</td><td>telencephalon regionalization</td><td>[http://www.uniprot.org/uniprot/?query=gene:LHX2+AND+taxonomy:9606+AND+reviewed:yes LHX2], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:BMP2+AND+taxonomy:9606+AND+reviewed:yes BMP2], [http://www.uniprot.org/uniprot/?query=gene:SHH+AND+taxonomy:9606+AND+reviewed:yes SHH]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0009798</td><td>axis specification</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT6+AND+taxonomy:9606+AND+reviewed:yes WNT6], [http://www.uniprot.org/uniprot/?query=gene:APC+AND+taxonomy:9606+AND+reviewed:yes APC]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009855</td><td>determination of bilateral symmetry</td><td>[http://www.uniprot.org/uniprot/?query=gene:ALDH1A2+AND+taxonomy:9606+AND+reviewed:yes ALDH1A2], [http://www.uniprot.org/uniprot/?query=gene:RALDH2+AND+taxonomy:9606+AND+reviewed:yes RALDH2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0065001</td><td>specification of axis polarity</td><td>[http://www.uniprot.org/uniprot/?query=gene:AHI1+AND+taxonomy:9606+AND+reviewed:yes AHI1], [http://www.uniprot.org/uniprot/?query=gene:BCOR+AND+taxonomy:9606+AND+reviewed:yes BCOR]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010085</td><td>polarity specification of proximal/distal axis</td><td>[http://www.uniprot.org/uniprot/?query=gene:NODAL+AND+taxonomy:9606+AND+reviewed:yes NODAL], [http://www.uniprot.org/uniprot/?query=gene:WNT8A+AND+taxonomy:9606+AND+reviewed:yes WNT8A]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0044241</td><td>lipid digestion</td><td>[http://www.uniprot.org/uniprot/?query=gene:PNLIP+AND+taxonomy:9606+AND+reviewed:yes PNLIP], [http://www.uniprot.org/uniprot/?query=gene:CEL+AND+taxonomy:9606+AND+reviewed:yes CEL], [http://www.uniprot.org/uniprot/?query=gene:CLPS+AND+taxonomy:9606+AND+reviewed:yes CLPS], [http://www.uniprot.org/uniprot/?query=gene:PNLIPRP2+AND+taxonomy:9606+AND+reviewed:yes PNLIPRP2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0042637</td><td>catagen</td><td>[http://www.uniprot.org/uniprot/?query=gene:TGFB2+AND+taxonomy:9606+AND+reviewed:yes TGFB2], [http://www.uniprot.org/uniprot/?query=gene:BARX2+AND+taxonomy:9606+AND+reviewed:yes BARX2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0048820</td><td>hair follicle maturation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ERCC2+AND+taxonomy:9606+AND+reviewed:yes ERCC2], [http://www.uniprot.org/uniprot/?query=gene:RBPJ+AND+taxonomy:9606+AND+reviewed:yes RBPJ]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0032902</td><td>nerve growth factor production</td><td>[http://www.uniprot.org/uniprot/?query=gene:PCSK6+AND+taxonomy:9606+AND+reviewed:yes PCSK6], [http://www.uniprot.org/uniprot/?query=gene:FURIN+AND+taxonomy:9606+AND+reviewed:yes FURIN]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0042596</td><td>fear response</td><td>[http://www.uniprot.org/uniprot/?query=gene:ADRA2A+AND+taxonomy:9606+AND+reviewed:yes ADRA2A], [http://www.uniprot.org/uniprot/?query=gene:DRD4+AND+taxonomy:9606+AND+reviewed:yes DRD4], [http://www.uniprot.org/uniprot/?query=gene:DBH+AND+taxonomy:9606+AND+reviewed:yes DBH], [http://www.uniprot.org/uniprot/?query=gene:ADRB1+AND+taxonomy:9606+AND+reviewed:yes ADRB1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0034381</td><td>plasma lipoprotein particle clearance</td><td>[http://www.uniprot.org/uniprot/?query=gene:MSR1+AND+taxonomy:9606+AND+reviewed:yes MSR1], [http://www.uniprot.org/uniprot/?query=gene:CD36+AND+taxonomy:9606+AND+reviewed:yes CD36]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0034447</td><td>very-low-density lipoprotein particle clearance</td><td>[http://www.uniprot.org/uniprot/?query=gene:APOC1+AND+taxonomy:9606+AND+reviewed:yes APOC1], [http://www.uniprot.org/uniprot/?query=gene:APOE+AND+taxonomy:9606+AND+reviewed:yes APOE], [http://www.uniprot.org/uniprot/?query=gene:VLDLR+AND+taxonomy:9606+AND+reviewed:yes VLDLR]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060437</td><td>lung growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:RSPO2+AND+taxonomy:9606+AND+reviewed:yes RSPO2], [http://www.uniprot.org/uniprot/?query=gene:SPRY2+AND+taxonomy:9606+AND+reviewed:yes SPRY2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0042633</td><td>hair cycle</td><td>[http://www.uniprot.org/uniprot/?query=gene:PTCH2+AND+taxonomy:9606+AND+reviewed:yes PTCH2], [http://www.uniprot.org/uniprot/?query=gene:PPP1R13L+AND+taxonomy:9606+AND+reviewed:yes PPP1R13L], [http://www.uniprot.org/uniprot/?query=gene:MPZL3+AND+taxonomy:9606+AND+reviewed:yes MPZL3], [http://www.uniprot.org/uniprot/?query=gene:SNRPE+AND+taxonomy:9606+AND+reviewed:yes SNRPE]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002248</td><td>connective tissue replacement involved in inflammatory response wound healing</td><td>[http://www.uniprot.org/uniprot/?query=gene:TGFB1+AND+taxonomy:9606+AND+reviewed:yes TGFB1], [http://www.uniprot.org/uniprot/?query=gene:HIF1A+AND+taxonomy:9606+AND+reviewed:yes HIF1A], [http://www.uniprot.org/uniprot/?query=gene:F2R+AND+taxonomy:9606+AND+reviewed:yes F2R]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0003294</td><td>atrial ventricular junction remodeling</td><td>[http://www.uniprot.org/uniprot/?query=gene:GJA1+AND+taxonomy:9606+AND+reviewed:yes GJA1], [http://www.uniprot.org/uniprot/?query=gene:GJA5+AND+taxonomy:9606+AND+reviewed:yes GJA5]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0048871</td><td>multicellular organismal homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:PPP1R13L+AND+taxonomy:9606+AND+reviewed:yes PPP1R13L], [http://www.uniprot.org/uniprot/?query=gene:TENC1+AND+taxonomy:9606+AND+reviewed:yes TENC1], [http://www.uniprot.org/uniprot/?query=gene:NDN+AND+taxonomy:9606+AND+reviewed:yes NDN]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0050878</td><td>regulation of body fluid levels</td><td>[http://www.uniprot.org/uniprot/?query=gene:PDSS2+AND+taxonomy:9606+AND+reviewed:yes PDSS2], [http://www.uniprot.org/uniprot/?query=gene:HEG1+AND+taxonomy:9606+AND+reviewed:yes HEG1], [http://www.uniprot.org/uniprot/?query=gene:EPHB2+AND+taxonomy:9606+AND+reviewed:yes EPHB2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0050882</td><td>voluntary musculoskeletal movement</td><td>[http://www.uniprot.org/uniprot/?query=gene:HIPK2+AND+taxonomy:9606+AND+reviewed:yes HIPK2], [http://www.uniprot.org/uniprot/?query=gene:ITPR1+AND+taxonomy:9606+AND+reviewed:yes ITPR1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0050883</td><td>musculoskeletal movement, spinal reflex action</td><td>[http://www.uniprot.org/uniprot/?query=gene:DRD3+AND+taxonomy:9606+AND+reviewed:yes DRD3], [http://www.uniprot.org/uniprot/?query=gene:CACNA1A+AND+taxonomy:9606+AND+reviewed:yes CACNA1A]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0007509</td><td>mesoderm migration involved in gastrulation</td><td>[http://www.uniprot.org/uniprot/?query=gene:EPB41L5+AND+taxonomy:9606+AND+reviewed:yes EPB41L5], [http://www.uniprot.org/uniprot/?query=gene:T+AND+taxonomy:9606+AND+reviewed:yes T]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0042249</td><td>establishment of planar polarity of embryonic epithelium</td><td>[http://www.uniprot.org/uniprot/?query=gene:FOXF2+AND+taxonomy:9606+AND+reviewed:yes FOXF2], [http://www.uniprot.org/uniprot/?query=gene:CELSR1+AND+taxonomy:9606+AND+reviewed:yes CELSR1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060197</td><td>cloacal septation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TP63+AND+taxonomy:9606+AND+reviewed:yes TP63], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:WNT11+AND+taxonomy:9606+AND+reviewed:yes WNT11]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0035922</td><td>foramen ovale closure</td><td>[http://www.uniprot.org/uniprot/?query=gene:TBX20+AND+taxonomy:9606+AND+reviewed:yes TBX20], [http://www.uniprot.org/uniprot/?query=gene:GJA5+AND+taxonomy:9606+AND+reviewed:yes GJA5]</td></tr>
 
<tr class="s2"><td>2</td><td>GO:0009838</td><td>abscission</td><td>[http://www.uniprot.org/uniprot/?query=gene:SPG20+AND+taxonomy:9606+AND+reviewed:yes SPG20], [http://www.uniprot.org/uniprot/?query=gene:IST1+AND+taxonomy:9606+AND+reviewed:yes IST1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0061042</td><td>vascular wound healing</td><td>[http://www.uniprot.org/uniprot/?query=gene:MCAM+AND+taxonomy:9606+AND+reviewed:yes MCAM], [http://www.uniprot.org/uniprot/?query=gene:CD34+AND+taxonomy:9606+AND+reviewed:yes CD34], [http://www.uniprot.org/uniprot/?query=gene:HPSE+AND+taxonomy:9606+AND+reviewed:yes HPSE]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0001705</td><td>ectoderm formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:LHX1+AND+taxonomy:9606+AND+reviewed:yes LHX1], [http://www.uniprot.org/uniprot/?query=gene:FOXA2+AND+taxonomy:9606+AND+reviewed:yes FOXA2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0048320</td><td>axial mesoderm formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:EPHA2+AND+taxonomy:9606+AND+reviewed:yes EPHA2], [http://www.uniprot.org/uniprot/?query=gene:AXIN1+AND+taxonomy:9606+AND+reviewed:yes AXIN1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0048341</td><td>paraxial mesoderm formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:HTT+AND+taxonomy:9606+AND+reviewed:yes HTT], [http://www.uniprot.org/uniprot/?query=gene:LEF1+AND+taxonomy:9606+AND+reviewed:yes LEF1], [http://www.uniprot.org/uniprot/?query=gene:HNF1A+AND+taxonomy:9606+AND+reviewed:yes HNF1A], [http://www.uniprot.org/uniprot/?query=gene:FOXC1+AND+taxonomy:9606+AND+reviewed:yes FOXC1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0003188</td><td>heart valve formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOX9+AND+taxonomy:9606+AND+reviewed:yes SOX9], [http://www.uniprot.org/uniprot/?query=gene:SCXA+AND+taxonomy:9606+AND+reviewed:yes SCXA]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0003190</td><td>atrioventricular valve formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SMAD4+AND+taxonomy:9606+AND+reviewed:yes SMAD4], [http://www.uniprot.org/uniprot/?query=gene:HEY1+AND+taxonomy:9606+AND+reviewed:yes HEY1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0003192</td><td>mitral valve formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOTCH1+AND+taxonomy:9606+AND+reviewed:yes NOTCH1], [http://www.uniprot.org/uniprot/?query=gene:ZFPM1+AND+taxonomy:9606+AND+reviewed:yes ZFPM1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0003193</td><td>pulmonary valve formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TBX20+AND+taxonomy:9606+AND+reviewed:yes TBX20], [http://www.uniprot.org/uniprot/?query=gene:GJA5+AND+taxonomy:9606+AND+reviewed:yes GJA5]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0003195</td><td>tricuspid valve formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ZFPM1+AND+taxonomy:9606+AND+reviewed:yes ZFPM1], [http://www.uniprot.org/uniprot/?query=gene:HEY2+AND+taxonomy:9606+AND+reviewed:yes HEY2]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0003207</td><td>cardiac chamber formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOTCH1+AND+taxonomy:9606+AND+reviewed:yes NOTCH1], [http://www.uniprot.org/uniprot/?query=gene:TBX20+AND+taxonomy:9606+AND+reviewed:yes TBX20]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0003218</td><td>cardiac left ventricle formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:HAND1+AND+taxonomy:9606+AND+reviewed:yes HAND1], [http://www.uniprot.org/uniprot/?query=gene:TBX5+AND+taxonomy:9606+AND+reviewed:yes TBX5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0003219</td><td>cardiac right ventricle formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOTCH1+AND+taxonomy:9606+AND+reviewed:yes NOTCH1], [http://www.uniprot.org/uniprot/?query=gene:HAND1+AND+taxonomy:9606+AND+reviewed:yes HAND1], [http://www.uniprot.org/uniprot/?query=gene:HAND2+AND+taxonomy:9606+AND+reviewed:yes HAND2], [http://www.uniprot.org/uniprot/?query=gene:SMARCD3+AND+taxonomy:9606+AND+reviewed:yes SMARCD3]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0003272</td><td>endocardial cushion formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TBX20+AND+taxonomy:9606+AND+reviewed:yes TBX20], [http://www.uniprot.org/uniprot/?query=gene:BMPR1A+AND+taxonomy:9606+AND+reviewed:yes BMPR1A]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010260</td><td>organ senescence</td><td>[http://www.uniprot.org/uniprot/?query=gene:PDX1+AND+taxonomy:9606+AND+reviewed:yes PDX1], [http://www.uniprot.org/uniprot/?query=gene:CTGF+AND+taxonomy:9606+AND+reviewed:yes CTGF]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0032289</td><td>central nervous system myelin formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ERCC2+AND+taxonomy:9606+AND+reviewed:yes ERCC2], [http://www.uniprot.org/uniprot/?query=gene:TENM4+AND+taxonomy:9606+AND+reviewed:yes TENM4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0032290</td><td>peripheral nervous system myelin formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:DICER1+AND+taxonomy:9606+AND+reviewed:yes DICER1], [http://www.uniprot.org/uniprot/?query=gene:NCMAP+AND+taxonomy:9606+AND+reviewed:yes NCMAP]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0014028</td><td>notochord formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:EPHA2+AND+taxonomy:9606+AND+reviewed:yes EPHA2], [http://www.uniprot.org/uniprot/?query=gene:T+AND+taxonomy:9606+AND+reviewed:yes T], [http://www.uniprot.org/uniprot/?query=gene:EFNA1+AND+taxonomy:9606+AND+reviewed:yes EFNA1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0021508</td><td>floor plate formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SMO+AND+taxonomy:9606+AND+reviewed:yes SMO], [http://www.uniprot.org/uniprot/?query=gene:FOXH1+AND+taxonomy:9606+AND+reviewed:yes FOXH1], [http://www.uniprot.org/uniprot/?query=gene:GLI2+AND+taxonomy:9606+AND+reviewed:yes GLI2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0021623</td><td>oculomotor nerve formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PHOX2A+AND+taxonomy:9606+AND+reviewed:yes PHOX2A], [http://www.uniprot.org/uniprot/?query=gene:TFAP2A+AND+taxonomy:9606+AND+reviewed:yes TFAP2A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021722</td><td>superior olivary nucleus maturation</td><td>[http://www.uniprot.org/uniprot/?query=gene:CDK5R1+AND+taxonomy:9606+AND+reviewed:yes CDK5R1], [http://www.uniprot.org/uniprot/?query=gene:CDK5R2+AND+taxonomy:9606+AND+reviewed:yes CDK5R2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070977</td><td>bone maturation</td><td>[http://www.uniprot.org/uniprot/?query=gene:GH1+AND+taxonomy:9606+AND+reviewed:yes GH1], [http://www.uniprot.org/uniprot/?query=gene:FGFR3+AND+taxonomy:9606+AND+reviewed:yes FGFR3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0034505</td><td>tooth mineralization</td><td>[http://www.uniprot.org/uniprot/?query=gene:COL1A1+AND+taxonomy:9606+AND+reviewed:yes COL1A1], [http://www.uniprot.org/uniprot/?query=gene:AMELX+AND+taxonomy:9606+AND+reviewed:yes AMELX]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001838</td><td>embryonic epithelial tube formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT4+AND+taxonomy:9606+AND+reviewed:yes WNT4], [http://www.uniprot.org/uniprot/?query=gene:SHANK3+AND+taxonomy:9606+AND+reviewed:yes SHANK3], [http://www.uniprot.org/uniprot/?query=gene:RET+AND+taxonomy:9606+AND+reviewed:yes RET]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0035802</td><td>adrenal cortex formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:CITED2+AND+taxonomy:9606+AND+reviewed:yes CITED2], [http://www.uniprot.org/uniprot/?query=gene:WT1+AND+taxonomy:9606+AND+reviewed:yes WT1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0048069</td><td>eye pigmentation</td><td>[http://www.uniprot.org/uniprot/?query=gene:LEF1+AND+taxonomy:9606+AND+reviewed:yes LEF1], [http://www.uniprot.org/uniprot/?query=gene:HPS1+AND+taxonomy:9606+AND+reviewed:yes HPS1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0021589</td><td>cerebellum structural organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:DAB1+AND+taxonomy:9606+AND+reviewed:yes DAB1], [http://www.uniprot.org/uniprot/?query=gene:HSPA5+AND+taxonomy:9606+AND+reviewed:yes HSPA5]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0021612</td><td>facial nerve structural organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:HOXA1+AND+taxonomy:9606+AND+reviewed:yes HOXA1], [http://www.uniprot.org/uniprot/?query=gene:EGR2+AND+taxonomy:9606+AND+reviewed:yes EGR2], [http://www.uniprot.org/uniprot/?query=gene:HOXB2+AND+taxonomy:9606+AND+reviewed:yes HOXB2], [http://www.uniprot.org/uniprot/?query=gene:HOXB1+AND+taxonomy:9606+AND+reviewed:yes HOXB1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0021633</td><td>optic nerve structural organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:KCNA2+AND+taxonomy:9606+AND+reviewed:yes KCNA2], [http://www.uniprot.org/uniprot/?query=gene:PAX2+AND+taxonomy:9606+AND+reviewed:yes PAX2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0001832</td><td>blastocyst growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:ZNF830+AND+taxonomy:9606+AND+reviewed:yes ZNF830], [http://www.uniprot.org/uniprot/?query=gene:UBTF+AND+taxonomy:9606+AND+reviewed:yes UBTF], [http://www.uniprot.org/uniprot/?query=gene:NBN+AND+taxonomy:9606+AND+reviewed:yes NBN], [http://www.uniprot.org/uniprot/?query=gene:SMARCA4+AND+taxonomy:9606+AND+reviewed:yes SMARCA4]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0048630</td><td>skeletal muscle tissue growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:CHRNA1+AND+taxonomy:9606+AND+reviewed:yes CHRNA1], [http://www.uniprot.org/uniprot/?query=gene:IGFBP5+AND+taxonomy:9606+AND+reviewed:yes IGFBP5], [http://www.uniprot.org/uniprot/?query=gene:CHRND+AND+taxonomy:9606+AND+reviewed:yes CHRND]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0072092</td><td>ureteric bud invasion</td><td>[http://www.uniprot.org/uniprot/?query=gene:SALL1+AND+taxonomy:9606+AND+reviewed:yes SALL1], [http://www.uniprot.org/uniprot/?query=gene:KIF26B+AND+taxonomy:9606+AND+reviewed:yes KIF26B]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060440</td><td>trachea formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4], [http://www.uniprot.org/uniprot/?query=gene:TGFBR2+AND+taxonomy:9606+AND+reviewed:yes TGFBR2], [http://www.uniprot.org/uniprot/?query=gene:CTNNB1+AND+taxonomy:9606+AND+reviewed:yes CTNNB1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0060914</td><td>heart formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17], [http://www.uniprot.org/uniprot/?query=gene:BMPR1A+AND+taxonomy:9606+AND+reviewed:yes BMPR1A]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0048859</td><td>formation of anatomical boundary</td><td>[http://www.uniprot.org/uniprot/?query=gene:NODAL+AND+taxonomy:9606+AND+reviewed:yes NODAL], [http://www.uniprot.org/uniprot/?query=gene:SMAD4+AND+taxonomy:9606+AND+reviewed:yes SMAD4], [http://www.uniprot.org/uniprot/?query=gene:SHH+AND+taxonomy:9606+AND+reviewed:yes SHH], [http://www.uniprot.org/uniprot/?query=gene:GDF3+AND+taxonomy:9606+AND+reviewed:yes GDF3]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0060033</td><td>anatomical structure regression</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT7B+AND+taxonomy:9606+AND+reviewed:yes WNT7B], [http://www.uniprot.org/uniprot/?query=gene:CD248+AND+taxonomy:9606+AND+reviewed:yes CD248], [http://www.uniprot.org/uniprot/?query=gene:LEF1+AND+taxonomy:9606+AND+reviewed:yes LEF1], [http://www.uniprot.org/uniprot/?query=gene:SPI1+AND+taxonomy:9606+AND+reviewed:yes SPI1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060032</td><td>notochord regression</td><td>[http://www.uniprot.org/uniprot/?query=gene:GLI2+AND+taxonomy:9606+AND+reviewed:yes GLI2], [http://www.uniprot.org/uniprot/?query=gene:GLI1+AND+taxonomy:9606+AND+reviewed:yes GLI1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0060061</td><td>Spemann organizer formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT1+AND+taxonomy:9606+AND+reviewed:yes WNT1], [http://www.uniprot.org/uniprot/?query=gene:FZD5+AND+taxonomy:9606+AND+reviewed:yes FZD5]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0060214</td><td>endocardium formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:OVOL2+AND+taxonomy:9606+AND+reviewed:yes OVOL2], [http://www.uniprot.org/uniprot/?query=gene:SOX18+AND+taxonomy:9606+AND+reviewed:yes SOX18], [http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17], [http://www.uniprot.org/uniprot/?query=gene:PROX1+AND+taxonomy:9606+AND+reviewed:yes PROX1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0060661</td><td>submandibular salivary gland formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:FGF10+AND+taxonomy:9606+AND+reviewed:yes FGF10], [http://www.uniprot.org/uniprot/?query=gene:CDC42+AND+taxonomy:9606+AND+reviewed:yes CDC42]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046619</td><td>optic placode formation involved in camera-type eye formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:FRS2+AND+taxonomy:9606+AND+reviewed:yes FRS2], [http://www.uniprot.org/uniprot/?query=gene:PROX1+AND+taxonomy:9606+AND+reviewed:yes PROX1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0030910</td><td>olfactory placode formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:AXIN1+AND+taxonomy:9606+AND+reviewed:yes AXIN1], [http://www.uniprot.org/uniprot/?query=gene:SOX2+AND+taxonomy:9606+AND+reviewed:yes SOX2], [http://www.uniprot.org/uniprot/?query=gene:POU2F1+AND+taxonomy:9606+AND+reviewed:yes POU2F1], [http://www.uniprot.org/uniprot/?query=gene:PROX1+AND+taxonomy:9606+AND+reviewed:yes PROX1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060596</td><td>mammary placode formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:LRP6+AND+taxonomy:9606+AND+reviewed:yes LRP6], [http://www.uniprot.org/uniprot/?query=gene:TBX2+AND+taxonomy:9606+AND+reviewed:yes TBX2], [http://www.uniprot.org/uniprot/?query=gene:NRG3+AND+taxonomy:9606+AND+reviewed:yes NRG3], [http://www.uniprot.org/uniprot/?query=gene:TBX3+AND+taxonomy:9606+AND+reviewed:yes TBX3]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0060900</td><td>embryonic camera-type eye formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:STRA6+AND+taxonomy:9606+AND+reviewed:yes STRA6], [http://www.uniprot.org/uniprot/?query=gene:TWIST1+AND+taxonomy:9606+AND+reviewed:yes TWIST1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0072033</td><td>renal vesicle formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT4+AND+taxonomy:9606+AND+reviewed:yes WNT4], [http://www.uniprot.org/uniprot/?query=gene:CTNNB1+AND+taxonomy:9606+AND+reviewed:yes CTNNB1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0072104</td><td>glomerular capillary formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOTCH3+AND+taxonomy:9606+AND+reviewed:yes NOTCH3], [http://www.uniprot.org/uniprot/?query=gene:BMP4+AND+taxonomy:9606+AND+reviewed:yes BMP4]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0072277</td><td>metanephric glomerular capillary formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TCF21+AND+taxonomy:9606+AND+reviewed:yes TCF21], [http://www.uniprot.org/uniprot/?query=gene:PDGFRB+AND+taxonomy:9606+AND+reviewed:yes PDGFRB], [http://www.uniprot.org/uniprot/?query=gene:PDGFRA+AND+taxonomy:9606+AND+reviewed:yes PDGFRA]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0072179</td><td>nephric duct formation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PAX2+AND+taxonomy:9606+AND+reviewed:yes PAX2], [http://www.uniprot.org/uniprot/?query=gene:GATA3+AND+taxonomy:9606+AND+reviewed:yes GATA3]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0044117</td><td>growth of symbiont in host</td><td>[http://www.uniprot.org/uniprot/?query=gene:PGLYRP3+AND+taxonomy:9606+AND+reviewed:yes PGLYRP3], [http://www.uniprot.org/uniprot/?query=gene:PGLYRP2+AND+taxonomy:9606+AND+reviewed:yes PGLYRP2], [http://www.uniprot.org/uniprot/?query=gene:PGLYRP1+AND+taxonomy:9606+AND+reviewed:yes PGLYRP1], [http://www.uniprot.org/uniprot/?query=gene:PGLYRP4+AND+taxonomy:9606+AND+reviewed:yes PGLYRP4]</td></tr>
 
<tr class="s1"><td>2</td><td>GO:0033058</td><td>directional locomotion</td><td>[http://www.uniprot.org/uniprot/?query=gene:GRIN2C+AND+taxonomy:9606+AND+reviewed:yes GRIN2C], [http://www.uniprot.org/uniprot/?query=gene:GRIN2A+AND+taxonomy:9606+AND+reviewed:yes GRIN2A], [http://www.uniprot.org/uniprot/?query=gene:ARPIN+AND+taxonomy:9606+AND+reviewed:yes ARPIN]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0003419</td><td>growth plate cartilage chondrocyte proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:CER1+AND+taxonomy:9606+AND+reviewed:yes CER1], [http://www.uniprot.org/uniprot/?query=gene:NPPC+AND+taxonomy:9606+AND+reviewed:yes NPPC]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0014009</td><td>glial cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:LGI4+AND+taxonomy:9606+AND+reviewed:yes LGI4], [http://www.uniprot.org/uniprot/?query=gene:SOX11+AND+taxonomy:9606+AND+reviewed:yes SOX11], [http://www.uniprot.org/uniprot/?query=gene:SOX4+AND+taxonomy:9606+AND+reviewed:yes SOX4], [http://www.uniprot.org/uniprot/?query=gene:PTK2B+AND+taxonomy:9606+AND+reviewed:yes PTK2B]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0014010</td><td>Schwann cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:CTNNB1+AND+taxonomy:9606+AND+reviewed:yes CTNNB1], [http://www.uniprot.org/uniprot/?query=gene:NF2+AND+taxonomy:9606+AND+reviewed:yes NF2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0048659</td><td>smooth muscle cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:EDNRA+AND+taxonomy:9606+AND+reviewed:yes EDNRA], [http://www.uniprot.org/uniprot/?query=gene:AGT+AND+taxonomy:9606+AND+reviewed:yes AGT], [http://www.uniprot.org/uniprot/?query=gene:NAA35+AND+taxonomy:9606+AND+reviewed:yes NAA35]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0033687</td><td>osteoblast proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:LRRC17+AND+taxonomy:9606+AND+reviewed:yes LRRC17], [http://www.uniprot.org/uniprot/?query=gene:OSR2+AND+taxonomy:9606+AND+reviewed:yes OSR2], [http://www.uniprot.org/uniprot/?query=gene:JUNB+AND+taxonomy:9606+AND+reviewed:yes JUNB], [http://www.uniprot.org/uniprot/?query=gene:FIGNL1+AND+taxonomy:9606+AND+reviewed:yes FIGNL1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0035726</td><td>common myeloid progenitor cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:UNCX+AND+taxonomy:9606+AND+reviewed:yes UNCX], [http://www.uniprot.org/uniprot/?query=gene:GSTP1+AND+taxonomy:9606+AND+reviewed:yes GSTP1], [http://www.uniprot.org/uniprot/?query=gene:FLT3+AND+taxonomy:9606+AND+reviewed:yes FLT3]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0048144</td><td>fibroblast proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNT7B+AND+taxonomy:9606+AND+reviewed:yes WNT7B], [http://www.uniprot.org/uniprot/?query=gene:EDNRA+AND+taxonomy:9606+AND+reviewed:yes EDNRA], [http://www.uniprot.org/uniprot/?query=gene:SP2+AND+taxonomy:9606+AND+reviewed:yes SP2], [http://www.uniprot.org/uniprot/?query=gene:AGT+AND+taxonomy:9606+AND+reviewed:yes AGT]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060750</td><td>epithelial cell proliferation involved in mammary gland duct elongation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TFAP2C+AND+taxonomy:9606+AND+reviewed:yes TFAP2C], [http://www.uniprot.org/uniprot/?query=gene:WNT5A+AND+taxonomy:9606+AND+reviewed:yes WNT5A], [http://www.uniprot.org/uniprot/?query=gene:MED1+AND+taxonomy:9606+AND+reviewed:yes MED1], [http://www.uniprot.org/uniprot/?query=gene:ESR1+AND+taxonomy:9606+AND+reviewed:yes ESR1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0051450</td><td>myoblast proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:IGF1+AND+taxonomy:9606+AND+reviewed:yes IGF1], [http://www.uniprot.org/uniprot/?query=gene:MET+AND+taxonomy:9606+AND+reviewed:yes MET], [http://www.uniprot.org/uniprot/?query=gene:HGF+AND+taxonomy:9606+AND+reviewed:yes HGF], [http://www.uniprot.org/uniprot/?query=gene:GPX1+AND+taxonomy:9606+AND+reviewed:yes GPX1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0033278</td><td>cell proliferation in midbrain</td><td>[http://www.uniprot.org/uniprot/?query=gene:FZD3+AND+taxonomy:9606+AND+reviewed:yes FZD3], [http://www.uniprot.org/uniprot/?query=gene:FZD6+AND+taxonomy:9606+AND+reviewed:yes FZD6]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002158</td><td>osteoclast proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NPR3+AND+taxonomy:9606+AND+reviewed:yes NPR3], [http://www.uniprot.org/uniprot/?query=gene:CSF1+AND+taxonomy:9606+AND+reviewed:yes CSF1], [http://www.uniprot.org/uniprot/?query=gene:TNFSF11+AND+taxonomy:9606+AND+reviewed:yes TNFSF11]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0032943</td><td>mononuclear cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:ACE+AND+taxonomy:9606+AND+reviewed:yes ACE], [http://www.uniprot.org/uniprot/?query=gene:TGFB1+AND+taxonomy:9606+AND+reviewed:yes TGFB1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010463</td><td>mesenchymal cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:HAND2+AND+taxonomy:9606+AND+reviewed:yes HAND2], [http://www.uniprot.org/uniprot/?query=gene:FGF7+AND+taxonomy:9606+AND+reviewed:yes FGF7], [http://www.uniprot.org/uniprot/?query=gene:FGF4+AND+taxonomy:9606+AND+reviewed:yes FGF4]</td></tr>
 
<tr class="s1"><td>2</td><td>GO:0016265</td><td>death</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC18A2+AND+taxonomy:9606+AND+reviewed:yes SLC18A2], [http://www.uniprot.org/uniprot/?query=gene:TCF15+AND+taxonomy:9606+AND+reviewed:yes TCF15], [http://www.uniprot.org/uniprot/?query=gene:NR4A2+AND+taxonomy:9606+AND+reviewed:yes NR4A2]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0001543</td><td>ovarian follicle rupture</td><td>[http://www.uniprot.org/uniprot/?query=gene:NRIP1+AND+taxonomy:9606+AND+reviewed:yes NRIP1], [http://www.uniprot.org/uniprot/?query=gene:AGT+AND+taxonomy:9606+AND+reviewed:yes AGT]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0001546</td><td>preantral ovarian follicle growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:GPR149+AND+taxonomy:9606+AND+reviewed:yes GPR149], [http://www.uniprot.org/uniprot/?query=gene:AMH+AND+taxonomy:9606+AND+reviewed:yes AMH]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0001550</td><td>ovarian cumulus expansion</td><td>[http://www.uniprot.org/uniprot/?query=gene:EREG+AND+taxonomy:9606+AND+reviewed:yes EREG], [http://www.uniprot.org/uniprot/?query=gene:BMPR1B+AND+taxonomy:9606+AND+reviewed:yes BMPR1B]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0001554</td><td>luteolysis</td><td>[http://www.uniprot.org/uniprot/?query=gene:MMP19+AND+taxonomy:9606+AND+reviewed:yes MMP19], [http://www.uniprot.org/uniprot/?query=gene:CASP2+AND+taxonomy:9606+AND+reviewed:yes CASP2]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0060112</td><td>generation of ovulation cycle rhythm</td><td>[http://www.uniprot.org/uniprot/?query=gene:KISS1+AND+taxonomy:9606+AND+reviewed:yes KISS1], [http://www.uniprot.org/uniprot/?query=gene:NPY5R+AND+taxonomy:9606+AND+reviewed:yes NPY5R]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0045475</td><td>locomotor rhythm</td><td>[http://www.uniprot.org/uniprot/?query=gene:KCNMA1+AND+taxonomy:9606+AND+reviewed:yes KCNMA1], [http://www.uniprot.org/uniprot/?query=gene:NPAS2+AND+taxonomy:9606+AND+reviewed:yes NPAS2], [http://www.uniprot.org/uniprot/?query=gene:NAGLU+AND+taxonomy:9606+AND+reviewed:yes NAGLU], [http://www.uniprot.org/uniprot/?query=gene:PTEN+AND+taxonomy:9606+AND+reviewed:yes PTEN]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0015993</td><td>molecular hydrogen transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC23A2+AND+taxonomy:9606+AND+reviewed:yes SLC23A2], [http://www.uniprot.org/uniprot/?query=gene:ADHFE1+AND+taxonomy:9606+AND+reviewed:yes ADHFE1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0043490</td><td>malate-aspartate shuttle</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC25A13+AND+taxonomy:9606+AND+reviewed:yes SLC25A13], [http://www.uniprot.org/uniprot/?query=gene:SLC25A12+AND+taxonomy:9606+AND+reviewed:yes SLC25A12]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0015918</td><td>sterol transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:ABCG5+AND+taxonomy:9606+AND+reviewed:yes ABCG5], [http://www.uniprot.org/uniprot/?query=gene:ABCG8+AND+taxonomy:9606+AND+reviewed:yes ABCG8], [http://www.uniprot.org/uniprot/?query=gene:NPC1L1+AND+taxonomy:9606+AND+reviewed:yes NPC1L1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0015920</td><td>lipopolysaccharide transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:LBP+AND+taxonomy:9606+AND+reviewed:yes LBP], [http://www.uniprot.org/uniprot/?query=gene:SCARB1+AND+taxonomy:9606+AND+reviewed:yes SCARB1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0015697</td><td>quaternary ammonium group transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC22A5+AND+taxonomy:9606+AND+reviewed:yes SLC22A5], [http://www.uniprot.org/uniprot/?query=gene:SLC22A3+AND+taxonomy:9606+AND+reviewed:yes SLC22A3], [http://www.uniprot.org/uniprot/?query=gene:SLC22A4+AND+taxonomy:9606+AND+reviewed:yes SLC22A4]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0015837</td><td>amine transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:AQP9+AND+taxonomy:9606+AND+reviewed:yes AQP9], [http://www.uniprot.org/uniprot/?query=gene:SLC22A16+AND+taxonomy:9606+AND+reviewed:yes SLC22A16], [http://www.uniprot.org/uniprot/?query=gene:RHCG+AND+taxonomy:9606+AND+reviewed:yes RHCG]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0015851</td><td>nucleobase transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC23A2+AND+taxonomy:9606+AND+reviewed:yes SLC23A2], [http://www.uniprot.org/uniprot/?query=gene:SLC23A1+AND+taxonomy:9606+AND+reviewed:yes SLC23A1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0048227</td><td>plasma membrane to endosome transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:SORT1+AND+taxonomy:9606+AND+reviewed:yes SORT1], [http://www.uniprot.org/uniprot/?query=gene:RAB11A+AND+taxonomy:9606+AND+reviewed:yes RAB11A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:1990126</td><td>retrograde transport, endosome to plasma membrane</td><td>[http://www.uniprot.org/uniprot/?query=gene:MICALL1+AND+taxonomy:9606+AND+reviewed:yes MICALL1], [http://www.uniprot.org/uniprot/?query=gene:RAB11B+AND+taxonomy:9606+AND+reviewed:yes RAB11B], [http://www.uniprot.org/uniprot/?query=gene:SNX27+AND+taxonomy:9606+AND+reviewed:yes SNX27]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0030185</td><td>nitric oxide transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:AQP1+AND+taxonomy:9606+AND+reviewed:yes AQP1], [http://www.uniprot.org/uniprot/?query=gene:EDN1+AND+taxonomy:9606+AND+reviewed:yes EDN1], [http://www.uniprot.org/uniprot/?query=gene:HBB+AND+taxonomy:9606+AND+reviewed:yes HBB]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0032066</td><td>nucleolus to nucleoplasm transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOC2L+AND+taxonomy:9606+AND+reviewed:yes NOC2L], [http://www.uniprot.org/uniprot/?query=gene:WRN+AND+taxonomy:9606+AND+reviewed:yes WRN], [http://www.uniprot.org/uniprot/?query=gene:TBRG1+AND+taxonomy:9606+AND+reviewed:yes TBRG1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0035526</td><td>retrograde transport, plasma membrane to Golgi</td><td>[http://www.uniprot.org/uniprot/?query=gene:USP6NL+AND+taxonomy:9606+AND+reviewed:yes USP6NL], [http://www.uniprot.org/uniprot/?query=gene:RAB43+AND+taxonomy:9606+AND+reviewed:yes RAB43]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0042045</td><td>epithelial fluid transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:EDN1+AND+taxonomy:9606+AND+reviewed:yes EDN1], [http://www.uniprot.org/uniprot/?query=gene:EDNRB+AND+taxonomy:9606+AND+reviewed:yes EDNRB], [http://www.uniprot.org/uniprot/?query=gene:SLC26A6+AND+taxonomy:9606+AND+reviewed:yes SLC26A6], [http://www.uniprot.org/uniprot/?query=gene:CSF2+AND+taxonomy:9606+AND+reviewed:yes CSF2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0046717</td><td>acid secretion</td><td>[http://www.uniprot.org/uniprot/?query=gene:DRD2+AND+taxonomy:9606+AND+reviewed:yes DRD2], [http://www.uniprot.org/uniprot/?query=gene:DRD3+AND+taxonomy:9606+AND+reviewed:yes DRD3], [http://www.uniprot.org/uniprot/?query=gene:SLC22A16+AND+taxonomy:9606+AND+reviewed:yes SLC22A16]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046967</td><td>cytosol to ER transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:TAP1+AND+taxonomy:9606+AND+reviewed:yes TAP1], [http://www.uniprot.org/uniprot/?query=gene:TAP2+AND+taxonomy:9606+AND+reviewed:yes TAP2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0015889</td><td>cobalamin transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:GIF+AND+taxonomy:9606+AND+reviewed:yes GIF], [http://www.uniprot.org/uniprot/?query=gene:TCN1+AND+taxonomy:9606+AND+reviewed:yes TCN1], [http://www.uniprot.org/uniprot/?query=gene:TCN2+AND+taxonomy:9606+AND+reviewed:yes TCN2], [http://www.uniprot.org/uniprot/?query=gene:CUBN+AND+taxonomy:9606+AND+reviewed:yes CUBN]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0070633</td><td>transepithelial transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:CXADR+AND+taxonomy:9606+AND+reviewed:yes CXADR], [http://www.uniprot.org/uniprot/?query=gene:SLC26A6+AND+taxonomy:9606+AND+reviewed:yes SLC26A6], [http://www.uniprot.org/uniprot/?query=gene:GPLD1+AND+taxonomy:9606+AND+reviewed:yes GPLD1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0071985</td><td>multivesicular body sorting pathway</td><td>[http://www.uniprot.org/uniprot/?query=gene:RAB27A+AND+taxonomy:9606+AND+reviewed:yes RAB27A], [http://www.uniprot.org/uniprot/?query=gene:RAB27B+AND+taxonomy:9606+AND+reviewed:yes RAB27B], [http://www.uniprot.org/uniprot/?query=gene:SYTL4+AND+taxonomy:9606+AND+reviewed:yes SYTL4], [http://www.uniprot.org/uniprot/?query=gene:EXPH5+AND+taxonomy:9606+AND+reviewed:yes EXPH5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0034436</td><td>glycoprotein transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:ABCG1+AND+taxonomy:9606+AND+reviewed:yes ABCG1], [http://www.uniprot.org/uniprot/?query=gene:VLDLR+AND+taxonomy:9606+AND+reviewed:yes VLDLR]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001941</td><td>postsynaptic membrane organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:CHRNB1+AND+taxonomy:9606+AND+reviewed:yes CHRNB1], [http://www.uniprot.org/uniprot/?query=gene:GDNF+AND+taxonomy:9606+AND+reviewed:yes GDNF]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010256</td><td>endomembrane system organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:ARFGEF1+AND+taxonomy:9606+AND+reviewed:yes ARFGEF1], [http://www.uniprot.org/uniprot/?query=gene:ARFGEF2+AND+taxonomy:9606+AND+reviewed:yes ARFGEF2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0031579</td><td>membrane raft organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:PPT1+AND+taxonomy:9606+AND+reviewed:yes PPT1], [http://www.uniprot.org/uniprot/?query=gene:CAV3+AND+taxonomy:9606+AND+reviewed:yes CAV3], [http://www.uniprot.org/uniprot/?query=gene:DLG1+AND+taxonomy:9606+AND+reviewed:yes DLG1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0033292</td><td>T-tubule organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:CAV3+AND+taxonomy:9606+AND+reviewed:yes CAV3], [http://www.uniprot.org/uniprot/?query=gene:ANK2+AND+taxonomy:9606+AND+reviewed:yes ANK2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0045161</td><td>neuronal ion channel clustering</td><td>[http://www.uniprot.org/uniprot/?query=gene:MTCH1+AND+taxonomy:9606+AND+reviewed:yes MTCH1], [http://www.uniprot.org/uniprot/?query=gene:PICK1+AND+taxonomy:9606+AND+reviewed:yes PICK1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0048499</td><td>synaptic vesicle membrane organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:AP3D1+AND+taxonomy:9606+AND+reviewed:yes AP3D1], [http://www.uniprot.org/uniprot/?query=gene:SYP+AND+taxonomy:9606+AND+reviewed:yes SYP]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0071709</td><td>membrane assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:SPTBN1+AND+taxonomy:9606+AND+reviewed:yes SPTBN1], [http://www.uniprot.org/uniprot/?query=gene:ANK3+AND+taxonomy:9606+AND+reviewed:yes ANK3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071763</td><td>nuclear membrane organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:TOR1A+AND+taxonomy:9606+AND+reviewed:yes TOR1A], [http://www.uniprot.org/uniprot/?query=gene:TOR1B+AND+taxonomy:9606+AND+reviewed:yes TOR1B], [http://www.uniprot.org/uniprot/?query=gene:TOR1AIP1+AND+taxonomy:9606+AND+reviewed:yes TOR1AIP1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0097035</td><td>regulation of membrane lipid distribution</td><td>[http://www.uniprot.org/uniprot/?query=gene:TRIAP1+AND+taxonomy:9606+AND+reviewed:yes TRIAP1], [http://www.uniprot.org/uniprot/?query=gene:PRELID1+AND+taxonomy:9606+AND+reviewed:yes PRELID1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0042745</td><td>circadian sleep/wake cycle</td><td>[http://www.uniprot.org/uniprot/?query=gene:TH+AND+taxonomy:9606+AND+reviewed:yes TH], [http://www.uniprot.org/uniprot/?query=gene:NPAS2+AND+taxonomy:9606+AND+reviewed:yes NPAS2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0002357</td><td>defense response to tumor cell</td><td>[http://www.uniprot.org/uniprot/?query=gene:PRF1+AND+taxonomy:9606+AND+reviewed:yes PRF1], [http://www.uniprot.org/uniprot/?query=gene:PLK5+AND+taxonomy:9606+AND+reviewed:yes PLK5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0002215</td><td>defense response to nematode</td><td>[http://www.uniprot.org/uniprot/?query=gene:EPX+AND+taxonomy:9606+AND+reviewed:yes EPX], [http://www.uniprot.org/uniprot/?query=gene:TNFSF4+AND+taxonomy:9606+AND+reviewed:yes TNFSF4]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010193</td><td>response to ozone</td><td>[http://www.uniprot.org/uniprot/?query=gene:SCGB1A1+AND+taxonomy:9606+AND+reviewed:yes SCGB1A1], [http://www.uniprot.org/uniprot/?query=gene:CYP2E1+AND+taxonomy:9606+AND+reviewed:yes CYP2E1], [http://www.uniprot.org/uniprot/?query=gene:NGF+AND+taxonomy:9606+AND+reviewed:yes NGF], [http://www.uniprot.org/uniprot/?query=gene:TACR1+AND+taxonomy:9606+AND+reviewed:yes TACR1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071731</td><td>response to nitric oxide</td><td>[http://www.uniprot.org/uniprot/?query=gene:CCL19+AND+taxonomy:9606+AND+reviewed:yes CCL19], [http://www.uniprot.org/uniprot/?query=gene:EGLN1+AND+taxonomy:9606+AND+reviewed:yes EGLN1], [http://www.uniprot.org/uniprot/?query=gene:CCR7+AND+taxonomy:9606+AND+reviewed:yes CCR7]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0001306</td><td>age-dependent response to oxidative stress</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOD2+AND+taxonomy:9606+AND+reviewed:yes SOD2], [http://www.uniprot.org/uniprot/?query=gene:CLN8+AND+taxonomy:9606+AND+reviewed:yes CLN8], [http://www.uniprot.org/uniprot/?query=gene:COQ7+AND+taxonomy:9606+AND+reviewed:yes COQ7]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0006982</td><td>response to lipid hydroperoxide</td><td>[http://www.uniprot.org/uniprot/?query=gene:APOA4+AND+taxonomy:9606+AND+reviewed:yes APOA4], [http://www.uniprot.org/uniprot/?query=gene:GPX3+AND+taxonomy:9606+AND+reviewed:yes GPX3]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0006991</td><td>response to sterol depletion</td><td>[http://www.uniprot.org/uniprot/?query=gene:LYN+AND+taxonomy:9606+AND+reviewed:yes LYN], [http://www.uniprot.org/uniprot/?query=gene:INSIG1+AND+taxonomy:9606+AND+reviewed:yes INSIG1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009414</td><td>response to water deprivation</td><td>[http://www.uniprot.org/uniprot/?query=gene:TH+AND+taxonomy:9606+AND+reviewed:yes TH], [http://www.uniprot.org/uniprot/?query=gene:CD9+AND+taxonomy:9606+AND+reviewed:yes CD9]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002246</td><td>wound healing involved in inflammatory response</td><td>[http://www.uniprot.org/uniprot/?query=gene:HMOX1+AND+taxonomy:9606+AND+reviewed:yes HMOX1], [http://www.uniprot.org/uniprot/?query=gene:CD44+AND+taxonomy:9606+AND+reviewed:yes CD44]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0034059</td><td>response to anoxia</td><td>[http://www.uniprot.org/uniprot/?query=gene:OXTR+AND+taxonomy:9606+AND+reviewed:yes OXTR], [http://www.uniprot.org/uniprot/?query=gene:CTGF+AND+taxonomy:9606+AND+reviewed:yes CTGF]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0035902</td><td>response to immobilization stress</td><td>[http://www.uniprot.org/uniprot/?query=gene:CRHR1+AND+taxonomy:9606+AND+reviewed:yes CRHR1], [http://www.uniprot.org/uniprot/?query=gene:TPH1+AND+taxonomy:9606+AND+reviewed:yes TPH1], [http://www.uniprot.org/uniprot/?query=gene:CRH+AND+taxonomy:9606+AND+reviewed:yes CRH], [http://www.uniprot.org/uniprot/?query=gene:UCN3+AND+taxonomy:9606+AND+reviewed:yes UCN3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051788</td><td>response to misfolded protein</td><td>[http://www.uniprot.org/uniprot/?query=gene:F12+AND+taxonomy:9606+AND+reviewed:yes F12], [http://www.uniprot.org/uniprot/?query=gene:HDAC6+AND+taxonomy:9606+AND+reviewed:yes HDAC6], [http://www.uniprot.org/uniprot/?query=gene:CLU+AND+taxonomy:9606+AND+reviewed:yes CLU]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0051409</td><td>response to nitrosative stress</td><td>[http://www.uniprot.org/uniprot/?query=gene:ADH5+AND+taxonomy:9606+AND+reviewed:yes ADH5], [http://www.uniprot.org/uniprot/?query=gene:GCLM+AND+taxonomy:9606+AND+reviewed:yes GCLM], [http://www.uniprot.org/uniprot/?query=gene:GCLC+AND+taxonomy:9606+AND+reviewed:yes GCLC], [http://www.uniprot.org/uniprot/?query=gene:DUSP6+AND+taxonomy:9606+AND+reviewed:yes DUSP6]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051599</td><td>response to hydrostatic pressure</td><td>[http://www.uniprot.org/uniprot/?query=gene:KRT8+AND+taxonomy:9606+AND+reviewed:yes KRT8], [http://www.uniprot.org/uniprot/?query=gene:NTRK1+AND+taxonomy:9606+AND+reviewed:yes NTRK1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002023</td><td>reduction of food intake in response to dietary excess</td><td>[http://www.uniprot.org/uniprot/?query=gene:NMUR2+AND+taxonomy:9606+AND+reviewed:yes NMUR2], [http://www.uniprot.org/uniprot/?query=gene:PRLH+AND+taxonomy:9606+AND+reviewed:yes PRLH]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009583</td><td>detection of light stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:PDE6B+AND+taxonomy:9606+AND+reviewed:yes PDE6B], [http://www.uniprot.org/uniprot/?query=gene:OPN3+AND+taxonomy:9606+AND+reviewed:yes OPN3]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0009590</td><td>detection of gravity</td><td>[http://www.uniprot.org/uniprot/?query=gene:OTOP1+AND+taxonomy:9606+AND+reviewed:yes OTOP1], [http://www.uniprot.org/uniprot/?query=gene:NOX3+AND+taxonomy:9606+AND+reviewed:yes NOX3]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0016048</td><td>detection of temperature stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:NGFR+AND+taxonomy:9606+AND+reviewed:yes NGFR], [http://www.uniprot.org/uniprot/?query=gene:DRGX+AND+taxonomy:9606+AND+reviewed:yes DRGX]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0035995</td><td>detection of muscle stretch</td><td>[http://www.uniprot.org/uniprot/?query=gene:TCAP+AND+taxonomy:9606+AND+reviewed:yes TCAP], [http://www.uniprot.org/uniprot/?query=gene:CSRP3+AND+taxonomy:9606+AND+reviewed:yes CSRP3], [http://www.uniprot.org/uniprot/?query=gene:TTN+AND+taxonomy:9606+AND+reviewed:yes TTN]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0050974</td><td>detection of mechanical stimulus involved in sensory perception</td><td>[http://www.uniprot.org/uniprot/?query=gene:SERPINE2+AND+taxonomy:9606+AND+reviewed:yes SERPINE2], [http://www.uniprot.org/uniprot/?query=gene:ASIC2+AND+taxonomy:9606+AND+reviewed:yes ASIC2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0010996</td><td>response to auditory stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:NTRK2+AND+taxonomy:9606+AND+reviewed:yes NTRK2], [http://www.uniprot.org/uniprot/?query=gene:CXCL10+AND+taxonomy:9606+AND+reviewed:yes CXCL10], [http://www.uniprot.org/uniprot/?query=gene:TACR1+AND+taxonomy:9606+AND+reviewed:yes TACR1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0035994</td><td>response to muscle stretch</td><td>[http://www.uniprot.org/uniprot/?query=gene:TCAP+AND+taxonomy:9606+AND+reviewed:yes TCAP], [http://www.uniprot.org/uniprot/?query=gene:ANKRD1+AND+taxonomy:9606+AND+reviewed:yes ANKRD1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0009991</td><td>response to extracellular stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:RASGRP4+AND+taxonomy:9606+AND+reviewed:yes RASGRP4], [http://www.uniprot.org/uniprot/?query=gene:RPS19+AND+taxonomy:9606+AND+reviewed:yes RPS19], [http://www.uniprot.org/uniprot/?query=gene:ACTA1+AND+taxonomy:9606+AND+reviewed:yes ACTA1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060005</td><td>vestibular reflex</td><td>[http://www.uniprot.org/uniprot/?query=gene:NR4A3+AND+taxonomy:9606+AND+reviewed:yes NR4A3], [http://www.uniprot.org/uniprot/?query=gene:TMC1+AND+taxonomy:9606+AND+reviewed:yes TMC1], [http://www.uniprot.org/uniprot/?query=gene:TMC2+AND+taxonomy:9606+AND+reviewed:yes TMC2]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0097195</td><td>pilomotor reflex</td><td>[http://www.uniprot.org/uniprot/?query=gene:HPN+AND+taxonomy:9606+AND+reviewed:yes HPN], [http://www.uniprot.org/uniprot/?query=gene:ADRA1A+AND+taxonomy:9606+AND+reviewed:yes ADRA1A], [http://www.uniprot.org/uniprot/?query=gene:NPNT+AND+taxonomy:9606+AND+reviewed:yes NPNT]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0002238</td><td>response to molecule of fungal origin</td><td>[http://www.uniprot.org/uniprot/?query=gene:MYD88+AND+taxonomy:9606+AND+reviewed:yes MYD88], [http://www.uniprot.org/uniprot/?query=gene:TLR2+AND+taxonomy:9606+AND+reviewed:yes TLR2]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0009595</td><td>detection of biotic stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLRP3+AND+taxonomy:9606+AND+reviewed:yes NLRP3], [http://www.uniprot.org/uniprot/?query=gene:NOD1+AND+taxonomy:9606+AND+reviewed:yes NOD1], [http://www.uniprot.org/uniprot/?query=gene:NOD2+AND+taxonomy:9606+AND+reviewed:yes NOD2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0001562</td><td>response to protozoan</td><td>[http://www.uniprot.org/uniprot/?query=gene:VTCN1+AND+taxonomy:9606+AND+reviewed:yes VTCN1], [http://www.uniprot.org/uniprot/?query=gene:SPN+AND+taxonomy:9606+AND+reviewed:yes SPN], [http://www.uniprot.org/uniprot/?query=gene:IER3+AND+taxonomy:9606+AND+reviewed:yes IER3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0009609</td><td>response to symbiotic bacterium</td><td>[http://www.uniprot.org/uniprot/?query=gene:GPX1+AND+taxonomy:9606+AND+reviewed:yes GPX1], [http://www.uniprot.org/uniprot/?query=gene:GPX2+AND+taxonomy:9606+AND+reviewed:yes GPX2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009597</td><td>detection of virus</td><td>[http://www.uniprot.org/uniprot/?query=gene:IFIH1+AND+taxonomy:9606+AND+reviewed:yes IFIH1], [http://www.uniprot.org/uniprot/?query=gene:DDX58+AND+taxonomy:9606+AND+reviewed:yes DDX58], [http://www.uniprot.org/uniprot/?query=gene:TLR3+AND+taxonomy:9606+AND+reviewed:yes TLR3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001878</td><td>response to yeast</td><td>[http://www.uniprot.org/uniprot/?query=gene:NCF1+AND+taxonomy:9606+AND+reviewed:yes NCF1], [http://www.uniprot.org/uniprot/?query=gene:MPO+AND+taxonomy:9606+AND+reviewed:yes MPO], [http://www.uniprot.org/uniprot/?query=gene:ELANE+AND+taxonomy:9606+AND+reviewed:yes ELANE], [http://www.uniprot.org/uniprot/?query=gene:PTX3+AND+taxonomy:9606+AND+reviewed:yes PTX3]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0009624</td><td>response to nematode</td><td>[http://www.uniprot.org/uniprot/?query=gene:IL25+AND+taxonomy:9606+AND+reviewed:yes IL25], [http://www.uniprot.org/uniprot/?query=gene:CYP1A1+AND+taxonomy:9606+AND+reviewed:yes CYP1A1], [http://www.uniprot.org/uniprot/?query=gene:ITLN1+AND+taxonomy:9606+AND+reviewed:yes ITLN1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0071502</td><td>cellular response to temperature stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:HTR1B+AND+taxonomy:9606+AND+reviewed:yes HTR1B], [http://www.uniprot.org/uniprot/?query=gene:HTR2B+AND+taxonomy:9606+AND+reviewed:yes HTR2B]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010447</td><td>response to acidity</td><td>[http://www.uniprot.org/uniprot/?query=gene:GPR65+AND+taxonomy:9606+AND+reviewed:yes GPR65], [http://www.uniprot.org/uniprot/?query=gene:SLC9A1+AND+taxonomy:9606+AND+reviewed:yes SLC9A1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0009642</td><td>response to light intensity</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC24A1+AND+taxonomy:9606+AND+reviewed:yes SLC24A1], [http://www.uniprot.org/uniprot/?query=gene:GNAT1+AND+taxonomy:9606+AND+reviewed:yes GNAT1], [http://www.uniprot.org/uniprot/?query=gene:GNAT2+AND+taxonomy:9606+AND+reviewed:yes GNAT2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009648</td><td>photoperiodism</td><td>[http://www.uniprot.org/uniprot/?query=gene:NMU+AND+taxonomy:9606+AND+reviewed:yes NMU], [http://www.uniprot.org/uniprot/?query=gene:CLOCK+AND+taxonomy:9606+AND+reviewed:yes CLOCK]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0009582</td><td>detection of abiotic stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:NPFFR2+AND+taxonomy:9606+AND+reviewed:yes NPFFR2], [http://www.uniprot.org/uniprot/?query=gene:TAC1+AND+taxonomy:9606+AND+reviewed:yes TAC1], [http://www.uniprot.org/uniprot/?query=gene:TIMELESS+AND+taxonomy:9606+AND+reviewed:yes TIMELESS], [http://www.uniprot.org/uniprot/?query=gene:TACR1+AND+taxonomy:9606+AND+reviewed:yes TACR1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0014878</td><td>response to electrical stimulus involved in regulation of muscle adaptation</td><td>[http://www.uniprot.org/uniprot/?query=gene:RPS6KB1+AND+taxonomy:9606+AND+reviewed:yes RPS6KB1], [http://www.uniprot.org/uniprot/?query=gene:TRIM63+AND+taxonomy:9606+AND+reviewed:yes TRIM63], [http://www.uniprot.org/uniprot/?query=gene:MYOG+AND+taxonomy:9606+AND+reviewed:yes MYOG]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0003032</td><td>detection of oxygen</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOD2+AND+taxonomy:9606+AND+reviewed:yes SOD2], [http://www.uniprot.org/uniprot/?query=gene:CYB5R4+AND+taxonomy:9606+AND+reviewed:yes CYB5R4], [http://www.uniprot.org/uniprot/?query=gene:SLC11A2+AND+taxonomy:9606+AND+reviewed:yes SLC11A2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0044321</td><td>response to leptin</td><td>[http://www.uniprot.org/uniprot/?query=gene:NR1D1+AND+taxonomy:9606+AND+reviewed:yes NR1D1], [http://www.uniprot.org/uniprot/?query=gene:STAR+AND+taxonomy:9606+AND+reviewed:yes STAR]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0097066</td><td>response to thyroid hormone</td><td>[http://www.uniprot.org/uniprot/?query=gene:HPN+AND+taxonomy:9606+AND+reviewed:yes HPN], [http://www.uniprot.org/uniprot/?query=gene:AK2+AND+taxonomy:9606+AND+reviewed:yes AK2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0003127</td><td>detection of nodal flow</td><td>[http://www.uniprot.org/uniprot/?query=gene:PKD2+AND+taxonomy:9606+AND+reviewed:yes PKD2], [http://www.uniprot.org/uniprot/?query=gene:PKD1L1+AND+taxonomy:9606+AND+reviewed:yes PKD1L1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0034776</td><td>response to histamine</td><td>[http://www.uniprot.org/uniprot/?query=gene:DRD4+AND+taxonomy:9606+AND+reviewed:yes DRD4], [http://www.uniprot.org/uniprot/?query=gene:DRD2+AND+taxonomy:9606+AND+reviewed:yes DRD2], [http://www.uniprot.org/uniprot/?query=gene:DRD3+AND+taxonomy:9606+AND+reviewed:yes DRD3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046898</td><td>response to cycloheximide</td><td>[http://www.uniprot.org/uniprot/?query=gene:BCL2L1+AND+taxonomy:9606+AND+reviewed:yes BCL2L1], [http://www.uniprot.org/uniprot/?query=gene:GHR+AND+taxonomy:9606+AND+reviewed:yes GHR]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0097338</td><td>response to clozapine</td><td>[http://www.uniprot.org/uniprot/?query=gene:PRKAR2B+AND+taxonomy:9606+AND+reviewed:yes PRKAR2B], [http://www.uniprot.org/uniprot/?query=gene:PRKACB+AND+taxonomy:9606+AND+reviewed:yes PRKACB]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0055098</td><td>response to low-density lipoprotein particle</td><td>[http://www.uniprot.org/uniprot/?query=gene:ABCA1+AND+taxonomy:9606+AND+reviewed:yes ABCA1], [http://www.uniprot.org/uniprot/?query=gene:SREBF2+AND+taxonomy:9606+AND+reviewed:yes SREBF2], [http://www.uniprot.org/uniprot/?query=gene:PPARG+AND+taxonomy:9606+AND+reviewed:yes PPARG]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0055099</td><td>response to high density lipoprotein particle</td><td>[http://www.uniprot.org/uniprot/?query=gene:ADAM17+AND+taxonomy:9606+AND+reviewed:yes ADAM17], [http://www.uniprot.org/uniprot/?query=gene:ABCG1+AND+taxonomy:9606+AND+reviewed:yes ABCG1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0014873</td><td>response to muscle activity involved in regulation of muscle adaptation</td><td>[http://www.uniprot.org/uniprot/?query=gene:AGT+AND+taxonomy:9606+AND+reviewed:yes AGT], [http://www.uniprot.org/uniprot/?query=gene:MYOG+AND+taxonomy:9606+AND+reviewed:yes MYOG]</td></tr>
 
<tr class="s1"><td>2</td><td>GO:0014854</td><td>response to inactivity</td><td>[http://www.uniprot.org/uniprot/?query=gene:DRD2+AND+taxonomy:9606+AND+reviewed:yes DRD2], [http://www.uniprot.org/uniprot/?query=gene:IL10+AND+taxonomy:9606+AND+reviewed:yes IL10]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0009593</td><td>detection of chemical stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:DRGX+AND+taxonomy:9606+AND+reviewed:yes DRGX], [http://www.uniprot.org/uniprot/?query=gene:UGT2A1+AND+taxonomy:9606+AND+reviewed:yes UGT2A1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0050968</td><td>detection of chemical stimulus involved in sensory perception of pain</td><td>[http://www.uniprot.org/uniprot/?query=gene:ASIC3+AND+taxonomy:9606+AND+reviewed:yes ASIC3], [http://www.uniprot.org/uniprot/?query=gene:TRPA1+AND+taxonomy:9606+AND+reviewed:yes TRPA1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046684</td><td>response to pyrethroid</td><td>[http://www.uniprot.org/uniprot/?query=gene:SCN1B+AND+taxonomy:9606+AND+reviewed:yes SCN1B], [http://www.uniprot.org/uniprot/?query=gene:TH+AND+taxonomy:9606+AND+reviewed:yes TH], [http://www.uniprot.org/uniprot/?query=gene:SCN2B+AND+taxonomy:9606+AND+reviewed:yes SCN2B], [http://www.uniprot.org/uniprot/?query=gene:DDC+AND+taxonomy:9606+AND+reviewed:yes DDC]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0060992</td><td>response to fungicide</td><td>[http://www.uniprot.org/uniprot/?query=gene:GRIN1+AND+taxonomy:9606+AND+reviewed:yes GRIN1], [http://www.uniprot.org/uniprot/?query=gene:CYP17A1+AND+taxonomy:9606+AND+reviewed:yes CYP17A1], [http://www.uniprot.org/uniprot/?query=gene:STAR+AND+taxonomy:9606+AND+reviewed:yes STAR], [http://www.uniprot.org/uniprot/?query=gene:CYP11A1+AND+taxonomy:9606+AND+reviewed:yes CYP11A1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0043331</td><td>response to dsRNA</td><td>[http://www.uniprot.org/uniprot/?query=gene:PMAIP1+AND+taxonomy:9606+AND+reviewed:yes PMAIP1], [http://www.uniprot.org/uniprot/?query=gene:PELI1+AND+taxonomy:9606+AND+reviewed:yes PELI1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070669</td><td>response to interleukin-2</td><td>[http://www.uniprot.org/uniprot/?query=gene:CITED1+AND+taxonomy:9606+AND+reviewed:yes CITED1], [http://www.uniprot.org/uniprot/?query=gene:STAT5B+AND+taxonomy:9606+AND+reviewed:yes STAT5B], [http://www.uniprot.org/uniprot/?query=gene:JAK3+AND+taxonomy:9606+AND+reviewed:yes JAK3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070671</td><td>response to interleukin-12</td><td>[http://www.uniprot.org/uniprot/?query=gene:RIPK2+AND+taxonomy:9606+AND+reviewed:yes RIPK2], [http://www.uniprot.org/uniprot/?query=gene:JAK2+AND+taxonomy:9606+AND+reviewed:yes JAK2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0070672</td><td>response to interleukin-15</td><td>[http://www.uniprot.org/uniprot/?query=gene:STAT5B+AND+taxonomy:9606+AND+reviewed:yes STAT5B], [http://www.uniprot.org/uniprot/?query=gene:JAK3+AND+taxonomy:9606+AND+reviewed:yes JAK3], [http://www.uniprot.org/uniprot/?query=gene:ACSL4+AND+taxonomy:9606+AND+reviewed:yes ACSL4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0070741</td><td>response to interleukin-6</td><td>[http://www.uniprot.org/uniprot/?query=gene:CITED1+AND+taxonomy:9606+AND+reviewed:yes CITED1], [http://www.uniprot.org/uniprot/?query=gene:CHI3L1+AND+taxonomy:9606+AND+reviewed:yes CHI3L1], [http://www.uniprot.org/uniprot/?query=gene:SFTPC+AND+taxonomy:9606+AND+reviewed:yes SFTPC], [http://www.uniprot.org/uniprot/?query=gene:FOXA2+AND+taxonomy:9606+AND+reviewed:yes FOXA2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0071104</td><td>response to interleukin-9</td><td>[http://www.uniprot.org/uniprot/?query=gene:CITED1+AND+taxonomy:9606+AND+reviewed:yes CITED1], [http://www.uniprot.org/uniprot/?query=gene:JAK3+AND+taxonomy:9606+AND+reviewed:yes JAK3]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0034465</td><td>response to carbon monoxide</td><td>[http://www.uniprot.org/uniprot/?query=gene:EGR1+AND+taxonomy:9606+AND+reviewed:yes EGR1], [http://www.uniprot.org/uniprot/?query=gene:KCNMA1+AND+taxonomy:9606+AND+reviewed:yes KCNMA1], [http://www.uniprot.org/uniprot/?query=gene:IL10+AND+taxonomy:9606+AND+reviewed:yes IL10]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0046683</td><td>response to organophosphorus</td><td>[http://www.uniprot.org/uniprot/?query=gene:TYMS+AND+taxonomy:9606+AND+reviewed:yes TYMS], [http://www.uniprot.org/uniprot/?query=gene:RFC3+AND+taxonomy:9606+AND+reviewed:yes RFC3], [http://www.uniprot.org/uniprot/?query=gene:AKR1C1+AND+taxonomy:9606+AND+reviewed:yes AKR1C1], [http://www.uniprot.org/uniprot/?query=gene:TRIM16+AND+taxonomy:9606+AND+reviewed:yes TRIM16]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010044</td><td>response to aluminum ion</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAOB+AND+taxonomy:9606+AND+reviewed:yes MAOB], [http://www.uniprot.org/uniprot/?query=gene:QDPR+AND+taxonomy:9606+AND+reviewed:yes QDPR], [http://www.uniprot.org/uniprot/?query=gene:LONP1+AND+taxonomy:9606+AND+reviewed:yes LONP1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0032025</td><td>response to cobalt ion</td><td>[http://www.uniprot.org/uniprot/?query=gene:D2HGDH+AND+taxonomy:9606+AND+reviewed:yes D2HGDH], [http://www.uniprot.org/uniprot/?query=gene:CASP8+AND+taxonomy:9606+AND+reviewed:yes CASP8]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010157</td><td>response to chlorate</td><td>[http://www.uniprot.org/uniprot/?query=gene:PTCH1+AND+taxonomy:9606+AND+reviewed:yes PTCH1], [http://www.uniprot.org/uniprot/?query=gene:PDX1+AND+taxonomy:9606+AND+reviewed:yes PDX1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0034021</td><td>response to silicon dioxide</td><td>[http://www.uniprot.org/uniprot/?query=gene:SOD2+AND+taxonomy:9606+AND+reviewed:yes SOD2], [http://www.uniprot.org/uniprot/?query=gene:SCGB1A1+AND+taxonomy:9606+AND+reviewed:yes SCGB1A1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0050906</td><td>detection of stimulus involved in sensory perception</td><td>[http://www.uniprot.org/uniprot/?query=gene:PPEF2+AND+taxonomy:9606+AND+reviewed:yes PPEF2], [http://www.uniprot.org/uniprot/?query=gene:PPEF1+AND+taxonomy:9606+AND+reviewed:yes PPEF1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0008105</td><td>asymmetric protein localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:SCRIB+AND+taxonomy:9606+AND+reviewed:yes SCRIB], [http://www.uniprot.org/uniprot/?query=gene:WNT7A+AND+taxonomy:9606+AND+reviewed:yes WNT7A], [http://www.uniprot.org/uniprot/?query=gene:COLQ+AND+taxonomy:9606+AND+reviewed:yes COLQ], [http://www.uniprot.org/uniprot/?query=gene:DYNC2H1+AND+taxonomy:9606+AND+reviewed:yes DYNC2H1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0045175</td><td>basal protein localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:NCKAP1+AND+taxonomy:9606+AND+reviewed:yes NCKAP1], [http://www.uniprot.org/uniprot/?query=gene:ERBB2IP+AND+taxonomy:9606+AND+reviewed:yes ERBB2IP]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0031503</td><td>protein complex localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:KIF17+AND+taxonomy:9606+AND+reviewed:yes KIF17], [http://www.uniprot.org/uniprot/?query=gene:BIRC5+AND+taxonomy:9606+AND+reviewed:yes BIRC5], [http://www.uniprot.org/uniprot/?query=gene:DNMT3B+AND+taxonomy:9606+AND+reviewed:yes DNMT3B], [http://www.uniprot.org/uniprot/?query=gene:FKBP4+AND+taxonomy:9606+AND+reviewed:yes FKBP4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071896</td><td>protein localization to adherens junction</td><td>[http://www.uniprot.org/uniprot/?query=gene:SCRIB+AND+taxonomy:9606+AND+reviewed:yes SCRIB], [http://www.uniprot.org/uniprot/?query=gene:DSP+AND+taxonomy:9606+AND+reviewed:yes DSP], [http://www.uniprot.org/uniprot/?query=gene:MPP7+AND+taxonomy:9606+AND+reviewed:yes MPP7]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:1901998</td><td>toxin transport</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC17A3+AND+taxonomy:9606+AND+reviewed:yes SLC17A3], [http://www.uniprot.org/uniprot/?query=gene:LRP6+AND+taxonomy:9606+AND+reviewed:yes LRP6], [http://www.uniprot.org/uniprot/?query=gene:ABCG1+AND+taxonomy:9606+AND+reviewed:yes ABCG1], [http://www.uniprot.org/uniprot/?query=gene:SLC7A8+AND+taxonomy:9606+AND+reviewed:yes SLC7A8]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0071169</td><td>establishment of protein localization to chromatin</td><td>[http://www.uniprot.org/uniprot/?query=gene:CCDC101+AND+taxonomy:9606+AND+reviewed:yes CCDC101], [http://www.uniprot.org/uniprot/?query=gene:LRWD1+AND+taxonomy:9606+AND+reviewed:yes LRWD1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0051303</td><td>establishment of chromosome localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:NDE1+AND+taxonomy:9606+AND+reviewed:yes NDE1], [http://www.uniprot.org/uniprot/?query=gene:BIRC5+AND+taxonomy:9606+AND+reviewed:yes BIRC5]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0051310</td><td>metaphase plate congression</td><td>[http://www.uniprot.org/uniprot/?query=gene:CENPF+AND+taxonomy:9606+AND+reviewed:yes CENPF], [http://www.uniprot.org/uniprot/?query=gene:SPICE1+AND+taxonomy:9606+AND+reviewed:yes SPICE1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0032401</td><td>establishment of melanosome localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:RAB17+AND+taxonomy:9606+AND+reviewed:yes RAB17], [http://www.uniprot.org/uniprot/?query=gene:SHROOM2+AND+taxonomy:9606+AND+reviewed:yes SHROOM2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051877</td><td>pigment granule aggregation in cell center</td><td>[http://www.uniprot.org/uniprot/?query=gene:MKKS+AND+taxonomy:9606+AND+reviewed:yes MKKS], [http://www.uniprot.org/uniprot/?query=gene:BBS4+AND+taxonomy:9606+AND+reviewed:yes BBS4], [http://www.uniprot.org/uniprot/?query=gene:BBS7+AND+taxonomy:9606+AND+reviewed:yes BBS7]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0051654</td><td>establishment of mitochondrion localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:PVRL2+AND+taxonomy:9606+AND+reviewed:yes PVRL2], [http://www.uniprot.org/uniprot/?query=gene:FEZ1+AND+taxonomy:9606+AND+reviewed:yes FEZ1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0051683</td><td>establishment of Golgi localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:ARHGAP21+AND+taxonomy:9606+AND+reviewed:yes ARHGAP21], [http://www.uniprot.org/uniprot/?query=gene:COPG1+AND+taxonomy:9606+AND+reviewed:yes COPG1], [http://www.uniprot.org/uniprot/?query=gene:CDC42+AND+taxonomy:9606+AND+reviewed:yes CDC42]</td></tr>
 
<tr class="s1"><td>2</td><td>GO:0009405</td><td>pathogenesis</td><td>[http://www.uniprot.org/uniprot/?query=gene:TMEM181+AND+taxonomy:9606+AND+reviewed:yes TMEM181], [http://www.uniprot.org/uniprot/?query=gene:MECP2+AND+taxonomy:9606+AND+reviewed:yes MECP2], [http://www.uniprot.org/uniprot/?query=gene:CARM1+AND+taxonomy:9606+AND+reviewed:yes CARM1]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0051702</td><td>interaction with symbiont</td><td>[http://www.uniprot.org/uniprot/?query=gene:GPX1+AND+taxonomy:9606+AND+reviewed:yes GPX1], [http://www.uniprot.org/uniprot/?query=gene:GPX2+AND+taxonomy:9606+AND+reviewed:yes GPX2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0002920</td><td>regulation of humoral immune response</td><td>[http://www.uniprot.org/uniprot/?query=gene:CD37+AND+taxonomy:9606+AND+reviewed:yes CD37], [http://www.uniprot.org/uniprot/?query=gene:SPNS2+AND+taxonomy:9606+AND+reviewed:yes SPNS2], [http://www.uniprot.org/uniprot/?query=gene:CXCL13+AND+taxonomy:9606+AND+reviewed:yes CXCL13]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0006808</td><td>regulation of nitrogen utilization</td><td>[http://www.uniprot.org/uniprot/?query=gene:BCL2+AND+taxonomy:9606+AND+reviewed:yes BCL2], [http://www.uniprot.org/uniprot/?query=gene:BAX+AND+taxonomy:9606+AND+reviewed:yes BAX]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0009890</td><td>negative regulation of biosynthetic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:GCHFR+AND+taxonomy:9606+AND+reviewed:yes GCHFR], [http://www.uniprot.org/uniprot/?query=gene:GSTP1+AND+taxonomy:9606+AND+reviewed:yes GSTP1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060267</td><td>positive regulation of respiratory burst</td><td>[http://www.uniprot.org/uniprot/?query=gene:INSR+AND+taxonomy:9606+AND+reviewed:yes INSR], [http://www.uniprot.org/uniprot/?query=gene:CAMK1D+AND+taxonomy:9606+AND+reviewed:yes CAMK1D], [http://www.uniprot.org/uniprot/?query=gene:INS+AND+taxonomy:9606+AND+reviewed:yes INS]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0032350</td><td>regulation of hormone metabolic process</td><td>[http://www.uniprot.org/uniprot/?query=gene:FSHR+AND+taxonomy:9606+AND+reviewed:yes FSHR], [http://www.uniprot.org/uniprot/?query=gene:TCF7L2+AND+taxonomy:9606+AND+reviewed:yes TCF7L2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060263</td><td>regulation of respiratory burst</td><td>[http://www.uniprot.org/uniprot/?query=gene:RAC2+AND+taxonomy:9606+AND+reviewed:yes RAC2], [http://www.uniprot.org/uniprot/?query=gene:RAC1+AND+taxonomy:9606+AND+reviewed:yes RAC1], [http://www.uniprot.org/uniprot/?query=gene:NOXO1+AND+taxonomy:9606+AND+reviewed:yes NOXO1], [http://www.uniprot.org/uniprot/?query=gene:NOXA1+AND+taxonomy:9606+AND+reviewed:yes NOXA1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0051712</td><td>positive regulation of killing of cells of other organism</td><td>[http://www.uniprot.org/uniprot/?query=gene:NOS2+AND+taxonomy:9606+AND+reviewed:yes NOS2], [http://www.uniprot.org/uniprot/?query=gene:IFNG+AND+taxonomy:9606+AND+reviewed:yes IFNG], [http://www.uniprot.org/uniprot/?query=gene:FCER2+AND+taxonomy:9606+AND+reviewed:yes FCER2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0031652</td><td>positive regulation of heat generation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC27A1+AND+taxonomy:9606+AND+reviewed:yes SLC27A1], [http://www.uniprot.org/uniprot/?query=gene:APLN+AND+taxonomy:9606+AND+reviewed:yes APLN]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:2000189</td><td>positive regulation of cholesterol homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:NR1D1+AND+taxonomy:9606+AND+reviewed:yes NR1D1], [http://www.uniprot.org/uniprot/?query=gene:ACOX1+AND+taxonomy:9606+AND+reviewed:yes ACOX1], [http://www.uniprot.org/uniprot/?query=gene:NR1H3+AND+taxonomy:9606+AND+reviewed:yes NR1H3], [http://www.uniprot.org/uniprot/?query=gene:HNF4A+AND+taxonomy:9606+AND+reviewed:yes HNF4A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:2000507</td><td>positive regulation of energy homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:SGIP1+AND+taxonomy:9606+AND+reviewed:yes SGIP1], [http://www.uniprot.org/uniprot/?query=gene:PPARGC1A+AND+taxonomy:9606+AND+reviewed:yes PPARGC1A]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0003254</td><td>regulation of membrane depolarization</td><td>[http://www.uniprot.org/uniprot/?query=gene:FHL1+AND+taxonomy:9606+AND+reviewed:yes FHL1], [http://www.uniprot.org/uniprot/?query=gene:NEDD4L+AND+taxonomy:9606+AND+reviewed:yes NEDD4L], [http://www.uniprot.org/uniprot/?query=gene:RANGRF+AND+taxonomy:9606+AND+reviewed:yes RANGRF]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0061088</td><td>regulation of sequestering of zinc ion</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLC30A8+AND+taxonomy:9606+AND+reviewed:yes SLC30A8], [http://www.uniprot.org/uniprot/?query=gene:SLC30A4+AND+taxonomy:9606+AND+reviewed:yes SLC30A4], [http://www.uniprot.org/uniprot/?query=gene:SLC30A3+AND+taxonomy:9606+AND+reviewed:yes SLC30A3], [http://www.uniprot.org/uniprot/?query=gene:AP3D1+AND+taxonomy:9606+AND+reviewed:yes AP3D1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:2000188</td><td>regulation of cholesterol homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:NR1D1+AND+taxonomy:9606+AND+reviewed:yes NR1D1], [http://www.uniprot.org/uniprot/?query=gene:SREBF2+AND+taxonomy:9606+AND+reviewed:yes SREBF2], [http://www.uniprot.org/uniprot/?query=gene:FGFR4+AND+taxonomy:9606+AND+reviewed:yes FGFR4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060178</td><td>regulation of exocyst localization</td><td>[http://www.uniprot.org/uniprot/?query=gene:RALB+AND+taxonomy:9606+AND+reviewed:yes RALB], [http://www.uniprot.org/uniprot/?query=gene:RALGAPA2+AND+taxonomy:9606+AND+reviewed:yes RALGAPA2], [http://www.uniprot.org/uniprot/?query=gene:RALGAPB+AND+taxonomy:9606+AND+reviewed:yes RALGAPB]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0060632</td><td>regulation of microtubule-based movement</td><td>[http://www.uniprot.org/uniprot/?query=gene:IGBP1+AND+taxonomy:9606+AND+reviewed:yes IGBP1], [http://www.uniprot.org/uniprot/?query=gene:MAPT+AND+taxonomy:9606+AND+reviewed:yes MAPT], [http://www.uniprot.org/uniprot/?query=gene:HDAC6+AND+taxonomy:9606+AND+reviewed:yes HDAC6]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0001560</td><td>regulation of cell growth by extracellular stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:KIF26A+AND+taxonomy:9606+AND+reviewed:yes KIF26A], [http://www.uniprot.org/uniprot/?query=gene:PPP1R9B+AND+taxonomy:9606+AND+reviewed:yes PPP1R9B], [http://www.uniprot.org/uniprot/?query=gene:MYOCD+AND+taxonomy:9606+AND+reviewed:yes MYOCD]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0040009</td><td>regulation of growth rate</td><td>[http://www.uniprot.org/uniprot/?query=gene:PARP1+AND+taxonomy:9606+AND+reviewed:yes PARP1], [http://www.uniprot.org/uniprot/?query=gene:WRN+AND+taxonomy:9606+AND+reviewed:yes WRN], [http://www.uniprot.org/uniprot/?query=gene:BNIPL+AND+taxonomy:9606+AND+reviewed:yes BNIPL]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060420</td><td>regulation of heart growth</td><td>[http://www.uniprot.org/uniprot/?query=gene:DUSP6+AND+taxonomy:9606+AND+reviewed:yes DUSP6], [http://www.uniprot.org/uniprot/?query=gene:MYH6+AND+taxonomy:9606+AND+reviewed:yes MYH6]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0042753</td><td>positive regulation of circadian rhythm</td><td>[http://www.uniprot.org/uniprot/?query=gene:BTRC+AND+taxonomy:9606+AND+reviewed:yes BTRC], [http://www.uniprot.org/uniprot/?query=gene:FBXW11+AND+taxonomy:9606+AND+reviewed:yes FBXW11]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060406</td><td>positive regulation of penile erection</td><td>[http://www.uniprot.org/uniprot/?query=gene:EDNRB+AND+taxonomy:9606+AND+reviewed:yes EDNRB], [http://www.uniprot.org/uniprot/?query=gene:OXT+AND+taxonomy:9606+AND+reviewed:yes OXT], [http://www.uniprot.org/uniprot/?query=gene:OXTR+AND+taxonomy:9606+AND+reviewed:yes OXTR], [http://www.uniprot.org/uniprot/?query=gene:P2RY1+AND+taxonomy:9606+AND+reviewed:yes P2RY1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0033623</td><td>regulation of integrin activation</td><td>[http://www.uniprot.org/uniprot/?query=gene:FBLIM1+AND+taxonomy:9606+AND+reviewed:yes FBLIM1], [http://www.uniprot.org/uniprot/?query=gene:FARP2+AND+taxonomy:9606+AND+reviewed:yes FARP2], [http://www.uniprot.org/uniprot/?query=gene:SELP+AND+taxonomy:9606+AND+reviewed:yes SELP]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060491</td><td>regulation of cell projection assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:CCL19+AND+taxonomy:9606+AND+reviewed:yes CCL19], [http://www.uniprot.org/uniprot/?query=gene:FAM110C+AND+taxonomy:9606+AND+reviewed:yes FAM110C]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0090083</td><td>regulation of inclusion body assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:SNCAIP+AND+taxonomy:9606+AND+reviewed:yes SNCAIP], [http://www.uniprot.org/uniprot/?query=gene:BAG5+AND+taxonomy:9606+AND+reviewed:yes BAG5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0090084</td><td>negative regulation of inclusion body assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:SACS+AND+taxonomy:9606+AND+reviewed:yes SACS], [http://www.uniprot.org/uniprot/?query=gene:HSPA1A+AND+taxonomy:9606+AND+reviewed:yes HSPA1A], [http://www.uniprot.org/uniprot/?query=gene:DNAJB2+AND+taxonomy:9606+AND+reviewed:yes DNAJB2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:1900106</td><td>positive regulation of hyaluranon cable assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:HAS3+AND+taxonomy:9606+AND+reviewed:yes HAS3], [http://www.uniprot.org/uniprot/?query=gene:BMP7+AND+taxonomy:9606+AND+reviewed:yes BMP7], [http://www.uniprot.org/uniprot/?query=gene:HYAL1+AND+taxonomy:9606+AND+reviewed:yes HYAL1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:1901888</td><td>regulation of cell junction assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:RAPGEF1+AND+taxonomy:9606+AND+reviewed:yes RAPGEF1], [http://www.uniprot.org/uniprot/?query=gene:RAPGEF2+AND+taxonomy:9606+AND+reviewed:yes RAPGEF2], [http://www.uniprot.org/uniprot/?query=gene:RAP1B+AND+taxonomy:9606+AND+reviewed:yes RAP1B], [http://www.uniprot.org/uniprot/?query=gene:RAP1A+AND+taxonomy:9606+AND+reviewed:yes RAP1A]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0043243</td><td>positive regulation of protein complex disassembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:TNF+AND+taxonomy:9606+AND+reviewed:yes TNF], [http://www.uniprot.org/uniprot/?query=gene:MGEA5+AND+taxonomy:9606+AND+reviewed:yes MGEA5], [http://www.uniprot.org/uniprot/?query=gene:BNIP3+AND+taxonomy:9606+AND+reviewed:yes BNIP3]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0050867</td><td>positive regulation of cell activation</td><td>[http://www.uniprot.org/uniprot/?query=gene:JAK2+AND+taxonomy:9606+AND+reviewed:yes JAK2], [http://www.uniprot.org/uniprot/?query=gene:CTGF+AND+taxonomy:9606+AND+reviewed:yes CTGF]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0090343</td><td>positive regulation of cell aging</td><td>[http://www.uniprot.org/uniprot/?query=gene:LMNA+AND+taxonomy:9606+AND+reviewed:yes LMNA], [http://www.uniprot.org/uniprot/?query=gene:TP53+AND+taxonomy:9606+AND+reviewed:yes TP53]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060760</td><td>positive regulation of response to cytokine stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:TAF9+AND+taxonomy:9606+AND+reviewed:yes TAF9], [http://www.uniprot.org/uniprot/?query=gene:WNT5A+AND+taxonomy:9606+AND+reviewed:yes WNT5A]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010902</td><td>positive regulation of very-low-density lipoprotein particle remodeling</td><td>[http://www.uniprot.org/uniprot/?query=gene:APOC2+AND+taxonomy:9606+AND+reviewed:yes APOC2], [http://www.uniprot.org/uniprot/?query=gene:APOA5+AND+taxonomy:9606+AND+reviewed:yes APOA5]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0060279</td><td>positive regulation of ovulation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PLAT+AND+taxonomy:9606+AND+reviewed:yes PLAT], [http://www.uniprot.org/uniprot/?query=gene:INHBA+AND+taxonomy:9606+AND+reviewed:yes INHBA], [http://www.uniprot.org/uniprot/?query=gene:INHBB+AND+taxonomy:9606+AND+reviewed:yes INHBB]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010716</td><td>negative regulation of extracellular matrix disassembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:CST3+AND+taxonomy:9606+AND+reviewed:yes CST3], [http://www.uniprot.org/uniprot/?query=gene:FAP+AND+taxonomy:9606+AND+reviewed:yes FAP], [http://www.uniprot.org/uniprot/?query=gene:DPP4+AND+taxonomy:9606+AND+reviewed:yes DPP4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0043242</td><td>negative regulation of protein complex disassembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLN+AND+taxonomy:9606+AND+reviewed:yes SLN], [http://www.uniprot.org/uniprot/?query=gene:TNF+AND+taxonomy:9606+AND+reviewed:yes TNF], [http://www.uniprot.org/uniprot/?query=gene:HDAC6+AND+taxonomy:9606+AND+reviewed:yes HDAC6], [http://www.uniprot.org/uniprot/?query=gene:IRAK3+AND+taxonomy:9606+AND+reviewed:yes IRAK3]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0051782</td><td>negative regulation of cell division</td><td>[http://www.uniprot.org/uniprot/?query=gene:PTCH1+AND+taxonomy:9606+AND+reviewed:yes PTCH1], [http://www.uniprot.org/uniprot/?query=gene:TXNIP+AND+taxonomy:9606+AND+reviewed:yes TXNIP], [http://www.uniprot.org/uniprot/?query=gene:BLM+AND+taxonomy:9606+AND+reviewed:yes BLM], [http://www.uniprot.org/uniprot/?query=gene:MYC+AND+taxonomy:9606+AND+reviewed:yes MYC]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0090288</td><td>negative regulation of cellular response to growth factor stimulus</td><td>[http://www.uniprot.org/uniprot/?query=gene:CASK+AND+taxonomy:9606+AND+reviewed:yes CASK], [http://www.uniprot.org/uniprot/?query=gene:SLIT2+AND+taxonomy:9606+AND+reviewed:yes SLIT2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:2000360</td><td>negative regulation of binding of sperm to zona pellucida</td><td>[http://www.uniprot.org/uniprot/?query=gene:ASTL+AND+taxonomy:9606+AND+reviewed:yes ASTL], [http://www.uniprot.org/uniprot/?query=gene:ZP3+AND+taxonomy:9606+AND+reviewed:yes ZP3], [http://www.uniprot.org/uniprot/?query=gene:ZP4+AND+taxonomy:9606+AND+reviewed:yes ZP4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010903</td><td>negative regulation of very-low-density lipoprotein particle remodeling</td><td>[http://www.uniprot.org/uniprot/?query=gene:APOC3+AND+taxonomy:9606+AND+reviewed:yes APOC3], [http://www.uniprot.org/uniprot/?query=gene:APOA1+AND+taxonomy:9606+AND+reviewed:yes APOA1], [http://www.uniprot.org/uniprot/?query=gene:APOA2+AND+taxonomy:9606+AND+reviewed:yes APOA2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0050819</td><td>negative regulation of coagulation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PROCR+AND+taxonomy:9606+AND+reviewed:yes PROCR], [http://www.uniprot.org/uniprot/?query=gene:HS3ST5+AND+taxonomy:9606+AND+reviewed:yes HS3ST5], [http://www.uniprot.org/uniprot/?query=gene:ANXA5+AND+taxonomy:9606+AND+reviewed:yes ANXA5], [http://www.uniprot.org/uniprot/?query=gene:ANXA4+AND+taxonomy:9606+AND+reviewed:yes ANXA4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:1900222</td><td>negative regulation of beta-amyloid clearance</td><td>[http://www.uniprot.org/uniprot/?query=gene:LRPAP1+AND+taxonomy:9606+AND+reviewed:yes LRPAP1], [http://www.uniprot.org/uniprot/?query=gene:SRF+AND+taxonomy:9606+AND+reviewed:yes SRF], [http://www.uniprot.org/uniprot/?query=gene:MYOCD+AND+taxonomy:9606+AND+reviewed:yes MYOCD]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0047484</td><td>regulation of response to osmotic stress</td><td>[http://www.uniprot.org/uniprot/?query=gene:MLC1+AND+taxonomy:9606+AND+reviewed:yes MLC1], [http://www.uniprot.org/uniprot/?query=gene:TRPV4+AND+taxonomy:9606+AND+reviewed:yes TRPV4], [http://www.uniprot.org/uniprot/?query=gene:GYPA+AND+taxonomy:9606+AND+reviewed:yes GYPA]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0061041</td><td>regulation of wound healing</td><td>[http://www.uniprot.org/uniprot/?query=gene:PLAU+AND+taxonomy:9606+AND+reviewed:yes PLAU], [http://www.uniprot.org/uniprot/?query=gene:VIL1+AND+taxonomy:9606+AND+reviewed:yes VIL1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:2001023</td><td>regulation of response to drug</td><td>[http://www.uniprot.org/uniprot/?query=gene:ADIRF+AND+taxonomy:9606+AND+reviewed:yes ADIRF], [http://www.uniprot.org/uniprot/?query=gene:GABRA4+AND+taxonomy:9606+AND+reviewed:yes GABRA4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:2001038</td><td>regulation of cellular response to drug</td><td>[http://www.uniprot.org/uniprot/?query=gene:NCOA1+AND+taxonomy:9606+AND+reviewed:yes NCOA1], [http://www.uniprot.org/uniprot/?query=gene:HMGA2+AND+taxonomy:9606+AND+reviewed:yes HMGA2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010453</td><td>regulation of cell fate commitment</td><td>[http://www.uniprot.org/uniprot/?query=gene:FGFR2+AND+taxonomy:9606+AND+reviewed:yes FGFR2], [http://www.uniprot.org/uniprot/?query=gene:PAX7+AND+taxonomy:9606+AND+reviewed:yes PAX7]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051147</td><td>regulation of muscle cell differentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:SUPT6H+AND+taxonomy:9606+AND+reviewed:yes SUPT6H], [http://www.uniprot.org/uniprot/?query=gene:CAMK1+AND+taxonomy:9606+AND+reviewed:yes CAMK1], [http://www.uniprot.org/uniprot/?query=gene:MEGF10+AND+taxonomy:9606+AND+reviewed:yes MEGF10]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010649</td><td>regulation of cell communication by electrical coupling</td><td>[http://www.uniprot.org/uniprot/?query=gene:CASQ2+AND+taxonomy:9606+AND+reviewed:yes CASQ2], [http://www.uniprot.org/uniprot/?query=gene:TRDN+AND+taxonomy:9606+AND+reviewed:yes TRDN], [http://www.uniprot.org/uniprot/?query=gene:ASPH+AND+taxonomy:9606+AND+reviewed:yes ASPH], [http://www.uniprot.org/uniprot/?query=gene:SRI+AND+taxonomy:9606+AND+reviewed:yes SRI]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:1901214</td><td>regulation of neuron death</td><td>[http://www.uniprot.org/uniprot/?query=gene:RILPL1+AND+taxonomy:9606+AND+reviewed:yes RILPL1], [http://www.uniprot.org/uniprot/?query=gene:SARM1+AND+taxonomy:9606+AND+reviewed:yes SARM1], [http://www.uniprot.org/uniprot/?query=gene:DHCR24+AND+taxonomy:9606+AND+reviewed:yes DHCR24]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0032878</td><td>regulation of establishment or maintenance of cell polarity</td><td>[http://www.uniprot.org/uniprot/?query=gene:IGF1+AND+taxonomy:9606+AND+reviewed:yes IGF1], [http://www.uniprot.org/uniprot/?query=gene:LLGL2+AND+taxonomy:9606+AND+reviewed:yes LLGL2], [http://www.uniprot.org/uniprot/?query=gene:TEK+AND+taxonomy:9606+AND+reviewed:yes TEK]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0032970</td><td>regulation of actin filament-based process</td><td>[http://www.uniprot.org/uniprot/?query=gene:PARD3+AND+taxonomy:9606+AND+reviewed:yes PARD3], [http://www.uniprot.org/uniprot/?query=gene:CNN2+AND+taxonomy:9606+AND+reviewed:yes CNN2], [http://www.uniprot.org/uniprot/?query=gene:FRMD6+AND+taxonomy:9606+AND+reviewed:yes FRMD6]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0090170</td><td>regulation of Golgi inheritance</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAPK3+AND+taxonomy:9606+AND+reviewed:yes MAPK3], [http://www.uniprot.org/uniprot/?query=gene:MAPK1+AND+taxonomy:9606+AND+reviewed:yes MAPK1], [http://www.uniprot.org/uniprot/?query=gene:MAP2K2+AND+taxonomy:9606+AND+reviewed:yes MAP2K2], [http://www.uniprot.org/uniprot/?query=gene:MAP2K1+AND+taxonomy:9606+AND+reviewed:yes MAP2K1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:1900063</td><td>regulation of peroxisome organization</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAVS+AND+taxonomy:9606+AND+reviewed:yes MAVS], [http://www.uniprot.org/uniprot/?query=gene:DNM1L+AND+taxonomy:9606+AND+reviewed:yes DNM1L], [http://www.uniprot.org/uniprot/?query=gene:MFF+AND+taxonomy:9606+AND+reviewed:yes MFF]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0014842</td><td>regulation of satellite cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:PAXBP1+AND+taxonomy:9606+AND+reviewed:yes PAXBP1], [http://www.uniprot.org/uniprot/?query=gene:CFLAR+AND+taxonomy:9606+AND+reviewed:yes CFLAR], [http://www.uniprot.org/uniprot/?query=gene:ANGPT1+AND+taxonomy:9606+AND+reviewed:yes ANGPT1], [http://www.uniprot.org/uniprot/?query=gene:MYOG+AND+taxonomy:9606+AND+reviewed:yes MYOG]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0033688</td><td>regulation of osteoblast proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:RHOA+AND+taxonomy:9606+AND+reviewed:yes RHOA], [http://www.uniprot.org/uniprot/?query=gene:NPR3+AND+taxonomy:9606+AND+reviewed:yes NPR3], [http://www.uniprot.org/uniprot/?query=gene:FGFR2+AND+taxonomy:9606+AND+reviewed:yes FGFR2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0072091</td><td>regulation of stem cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:AGO3+AND+taxonomy:9606+AND+reviewed:yes AGO3], [http://www.uniprot.org/uniprot/?query=gene:SOX18+AND+taxonomy:9606+AND+reviewed:yes SOX18], [http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17], [http://www.uniprot.org/uniprot/?query=gene:YAP1+AND+taxonomy:9606+AND+reviewed:yes YAP1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:2000254</td><td>regulation of male germ cell proliferation</td><td>[http://www.uniprot.org/uniprot/?query=gene:RHBDD1+AND+taxonomy:9606+AND+reviewed:yes RHBDD1], [http://www.uniprot.org/uniprot/?query=gene:RSPO1+AND+taxonomy:9606+AND+reviewed:yes RSPO1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0051823</td><td>regulation of synapse structural plasticity</td><td>[http://www.uniprot.org/uniprot/?query=gene:CAMK2B+AND+taxonomy:9606+AND+reviewed:yes CAMK2B], [http://www.uniprot.org/uniprot/?query=gene:CTNNA2+AND+taxonomy:9606+AND+reviewed:yes CTNNA2], [http://www.uniprot.org/uniprot/?query=gene:NCAN+AND+taxonomy:9606+AND+reviewed:yes NCAN], [http://www.uniprot.org/uniprot/?query=gene:DMPK+AND+taxonomy:9606+AND+reviewed:yes DMPK]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0009786</td><td>regulation of asymmetric cell division</td><td>[http://www.uniprot.org/uniprot/?query=gene:POU5F1+AND+taxonomy:9606+AND+reviewed:yes POU5F1], [http://www.uniprot.org/uniprot/?query=gene:WNT9B+AND+taxonomy:9606+AND+reviewed:yes WNT9B]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:2000035</td><td>regulation of stem cell division</td><td>[http://www.uniprot.org/uniprot/?query=gene:SFRP2+AND+taxonomy:9606+AND+reviewed:yes SFRP2], [http://www.uniprot.org/uniprot/?query=gene:SOX17+AND+taxonomy:9606+AND+reviewed:yes SOX17]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0060968</td><td>regulation of gene silencing</td><td>[http://www.uniprot.org/uniprot/?query=gene:HIST1H3A+AND+taxonomy:9606+AND+reviewed:yes HIST1H3A], [http://www.uniprot.org/uniprot/?query=gene:CDK2+AND+taxonomy:9606+AND+reviewed:yes CDK2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:2000327</td><td>positive regulation of ligand-dependent nuclear receptor transcription coactivator activity</td><td>[http://www.uniprot.org/uniprot/?query=gene:RQCD1+AND+taxonomy:9606+AND+reviewed:yes RQCD1], [http://www.uniprot.org/uniprot/?query=gene:CNOT6+AND+taxonomy:9606+AND+reviewed:yes CNOT6]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0032649</td><td>regulation of interferon-gamma production</td><td>[http://www.uniprot.org/uniprot/?query=gene:RIPK3+AND+taxonomy:9606+AND+reviewed:yes RIPK3], [http://www.uniprot.org/uniprot/?query=gene:ISG15+AND+taxonomy:9606+AND+reviewed:yes ISG15], [http://www.uniprot.org/uniprot/?query=gene:CCR7+AND+taxonomy:9606+AND+reviewed:yes CCR7]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0032675</td><td>regulation of interleukin-6 production</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAPKAPK2+AND+taxonomy:9606+AND+reviewed:yes MAPKAPK2], [http://www.uniprot.org/uniprot/?query=gene:HLA-B+AND+taxonomy:9606+AND+reviewed:yes HLA-B], [http://www.uniprot.org/uniprot/?query=gene:AFAP1L2+AND+taxonomy:9606+AND+reviewed:yes AFAP1L2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0032680</td><td>regulation of tumor necrosis factor production</td><td>[http://www.uniprot.org/uniprot/?query=gene:MAPKAPK2+AND+taxonomy:9606+AND+reviewed:yes MAPKAPK2], [http://www.uniprot.org/uniprot/?query=gene:TBC1D23+AND+taxonomy:9606+AND+reviewed:yes TBC1D23], [http://www.uniprot.org/uniprot/?query=gene:ZFP36+AND+taxonomy:9606+AND+reviewed:yes ZFP36], [http://www.uniprot.org/uniprot/?query=gene:LTF+AND+taxonomy:9606+AND+reviewed:yes LTF]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0034344</td><td>regulation of type III interferon production</td><td>[http://www.uniprot.org/uniprot/?query=gene:IFIH1+AND+taxonomy:9606+AND+reviewed:yes IFIH1], [http://www.uniprot.org/uniprot/?query=gene:DDX58+AND+taxonomy:9606+AND+reviewed:yes DDX58]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0010988</td><td>regulation of low-density lipoprotein particle clearance</td><td>[http://www.uniprot.org/uniprot/?query=gene:HNRNPK+AND+taxonomy:9606+AND+reviewed:yes HNRNPK], [http://www.uniprot.org/uniprot/?query=gene:CNPY2+AND+taxonomy:9606+AND+reviewed:yes CNPY2], [http://www.uniprot.org/uniprot/?query=gene:FGF21+AND+taxonomy:9606+AND+reviewed:yes FGF21]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0034103</td><td>regulation of tissue remodeling</td><td>[http://www.uniprot.org/uniprot/?query=gene:CST3+AND+taxonomy:9606+AND+reviewed:yes CST3], [http://www.uniprot.org/uniprot/?query=gene:TP53+AND+taxonomy:9606+AND+reviewed:yes TP53], [http://www.uniprot.org/uniprot/?query=gene:THBS4+AND+taxonomy:9606+AND+reviewed:yes THBS4]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0046850</td><td>regulation of bone remodeling</td><td>[http://www.uniprot.org/uniprot/?query=gene:INPP4B+AND+taxonomy:9606+AND+reviewed:yes INPP4B], [http://www.uniprot.org/uniprot/?query=gene:SUCO+AND+taxonomy:9606+AND+reviewed:yes SUCO], [http://www.uniprot.org/uniprot/?query=gene:GJA1+AND+taxonomy:9606+AND+reviewed:yes GJA1]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0042634</td><td>regulation of hair cycle</td><td>[http://www.uniprot.org/uniprot/?query=gene:NIPBL+AND+taxonomy:9606+AND+reviewed:yes NIPBL], [http://www.uniprot.org/uniprot/?query=gene:FA2H+AND+taxonomy:9606+AND+reviewed:yes FA2H]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0044065</td><td>regulation of respiratory system process</td><td>[http://www.uniprot.org/uniprot/?query=gene:MTG2+AND+taxonomy:9606+AND+reviewed:yes MTG2], [http://www.uniprot.org/uniprot/?query=gene:MTG1+AND+taxonomy:9606+AND+reviewed:yes MTG1], [http://www.uniprot.org/uniprot/?query=gene:FTO+AND+taxonomy:9606+AND+reviewed:yes FTO]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0051917</td><td>regulation of fibrinolysis</td><td>[http://www.uniprot.org/uniprot/?query=gene:APOH+AND+taxonomy:9606+AND+reviewed:yes APOH], [http://www.uniprot.org/uniprot/?query=gene:FAP+AND+taxonomy:9606+AND+reviewed:yes FAP]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0097006</td><td>regulation of plasma lipoprotein particle levels</td><td>[http://www.uniprot.org/uniprot/?query=gene:LPCAT3+AND+taxonomy:9606+AND+reviewed:yes LPCAT3], [http://www.uniprot.org/uniprot/?query=gene:DGAT2+AND+taxonomy:9606+AND+reviewed:yes DGAT2]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:1900271</td><td>regulation of long-term synaptic potentiation</td><td>[http://www.uniprot.org/uniprot/?query=gene:NLGN3+AND+taxonomy:9606+AND+reviewed:yes NLGN3], [http://www.uniprot.org/uniprot/?query=gene:SHANK3+AND+taxonomy:9606+AND+reviewed:yes SHANK3]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0080154</td><td>regulation of fertilization</td><td>[http://www.uniprot.org/uniprot/?query=gene:RNASE10+AND+taxonomy:9606+AND+reviewed:yes RNASE10], [http://www.uniprot.org/uniprot/?query=gene:ASUN+AND+taxonomy:9606+AND+reviewed:yes ASUN], [http://www.uniprot.org/uniprot/?query=gene:PLCB1+AND+taxonomy:9606+AND+reviewed:yes PLCB1]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0001505</td><td>regulation of neurotransmitter levels</td><td>[http://www.uniprot.org/uniprot/?query=gene:ZNF219+AND+taxonomy:9606+AND+reviewed:yes ZNF219], [http://www.uniprot.org/uniprot/?query=gene:GABRA2+AND+taxonomy:9606+AND+reviewed:yes GABRA2], [http://www.uniprot.org/uniprot/?query=gene:PDE1B+AND+taxonomy:9606+AND+reviewed:yes PDE1B], [http://www.uniprot.org/uniprot/?query=gene:DVL1+AND+taxonomy:9606+AND+reviewed:yes DVL1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0014916</td><td>regulation of lung blood pressure</td><td>[http://www.uniprot.org/uniprot/?query=gene:GCH1+AND+taxonomy:9606+AND+reviewed:yes GCH1], [http://www.uniprot.org/uniprot/?query=gene:BMPR2+AND+taxonomy:9606+AND+reviewed:yes BMPR2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0003085</td><td>negative regulation of systemic arterial blood pressure</td><td>[http://www.uniprot.org/uniprot/?query=gene:NEDD4L+AND+taxonomy:9606+AND+reviewed:yes NEDD4L], [http://www.uniprot.org/uniprot/?query=gene:IER3+AND+taxonomy:9606+AND+reviewed:yes IER3], [http://www.uniprot.org/uniprot/?query=gene:BBS4+AND+taxonomy:9606+AND+reviewed:yes BBS4], [http://www.uniprot.org/uniprot/?query=gene:BMPR2+AND+taxonomy:9606+AND+reviewed:yes BMPR2]</td></tr>
 
<tr class="s2"><td>3</td><td>GO:0010817</td><td>regulation of hormone levels</td><td>[http://www.uniprot.org/uniprot/?query=gene:BCAT2+AND+taxonomy:9606+AND+reviewed:yes BCAT2], [http://www.uniprot.org/uniprot/?query=gene:FOXA3+AND+taxonomy:9606+AND+reviewed:yes FOXA3], [http://www.uniprot.org/uniprot/?query=gene:FOXA2+AND+taxonomy:9606+AND+reviewed:yes FOXA2], [http://www.uniprot.org/uniprot/?query=gene:SOX8+AND+taxonomy:9606+AND+reviewed:yes SOX8]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0045759</td><td>negative regulation of action potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:CNR1+AND+taxonomy:9606+AND+reviewed:yes CNR1], [http://www.uniprot.org/uniprot/?query=gene:CNR2+AND+taxonomy:9606+AND+reviewed:yes CNR2], [http://www.uniprot.org/uniprot/?query=gene:CHRNB2+AND+taxonomy:9606+AND+reviewed:yes CHRNB2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0086001</td><td>regulation of cardiac muscle cell action potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:DMD+AND+taxonomy:9606+AND+reviewed:yes DMD], [http://www.uniprot.org/uniprot/?query=gene:PKP2+AND+taxonomy:9606+AND+reviewed:yes PKP2]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010917</td><td>negative regulation of mitochondrial membrane potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:PMAIP1+AND+taxonomy:9606+AND+reviewed:yes PMAIP1], [http://www.uniprot.org/uniprot/?query=gene:PRELID1+AND+taxonomy:9606+AND+reviewed:yes PRELID1]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0045838</td><td>positive regulation of membrane potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:PIAS3+AND+taxonomy:9606+AND+reviewed:yes PIAS3], [http://www.uniprot.org/uniprot/?query=gene:ANK3+AND+taxonomy:9606+AND+reviewed:yes ANK3], [http://www.uniprot.org/uniprot/?query=gene:GIMAP5+AND+taxonomy:9606+AND+reviewed:yes GIMAP5]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0010918</td><td>positive regulation of mitochondrial membrane potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:STOML2+AND+taxonomy:9606+AND+reviewed:yes STOML2], [http://www.uniprot.org/uniprot/?query=gene:BAD+AND+taxonomy:9606+AND+reviewed:yes BAD]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0086010</td><td>membrane depolarization involved in regulation of action potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:YWHAH+AND+taxonomy:9606+AND+reviewed:yes YWHAH], [http://www.uniprot.org/uniprot/?query=gene:SCN3B+AND+taxonomy:9606+AND+reviewed:yes SCN3B], [http://www.uniprot.org/uniprot/?query=gene:KCNH2+AND+taxonomy:9606+AND+reviewed:yes KCNH2], [http://www.uniprot.org/uniprot/?query=gene:SCN5A+AND+taxonomy:9606+AND+reviewed:yes SCN5A]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0060075</td><td>regulation of resting membrane potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:KCNJ10+AND+taxonomy:9606+AND+reviewed:yes KCNJ10], [http://www.uniprot.org/uniprot/?query=gene:PSEN1+AND+taxonomy:9606+AND+reviewed:yes PSEN1], [http://www.uniprot.org/uniprot/?query=gene:KCNJ2+AND+taxonomy:9606+AND+reviewed:yes KCNJ2]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0086036</td><td>regulation of cardiac muscle cell membrane potential</td><td>[http://www.uniprot.org/uniprot/?query=gene:ATP2A2+AND+taxonomy:9606+AND+reviewed:yes ATP2A2], [http://www.uniprot.org/uniprot/?query=gene:TRDN+AND+taxonomy:9606+AND+reviewed:yes TRDN], [http://www.uniprot.org/uniprot/?query=gene:EHD3+AND+taxonomy:9606+AND+reviewed:yes EHD3], [http://www.uniprot.org/uniprot/?query=gene:PLN+AND+taxonomy:9606+AND+reviewed:yes PLN]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0030104</td><td>water homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:IGF1+AND+taxonomy:9606+AND+reviewed:yes IGF1], [http://www.uniprot.org/uniprot/?query=gene:AQP9+AND+taxonomy:9606+AND+reviewed:yes AQP9], [http://www.uniprot.org/uniprot/?query=gene:NEDD4L+AND+taxonomy:9606+AND+reviewed:yes NEDD4L], [http://www.uniprot.org/uniprot/?query=gene:GHRHR+AND+taxonomy:9606+AND+reviewed:yes GHRHR]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0050801</td><td>ion homeostasis</td><td>[http://www.uniprot.org/uniprot/?query=gene:WNK4+AND+taxonomy:9606+AND+reviewed:yes WNK4], [http://www.uniprot.org/uniprot/?query=gene:KLHL3+AND+taxonomy:9606+AND+reviewed:yes KLHL3], [http://www.uniprot.org/uniprot/?query=gene:AMELX+AND+taxonomy:9606+AND+reviewed:yes AMELX], [http://www.uniprot.org/uniprot/?query=gene:CRH+AND+taxonomy:9606+AND+reviewed:yes CRH]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0050803</td><td>regulation of synapse structure and activity</td><td>[http://www.uniprot.org/uniprot/?query=gene:PPT1+AND+taxonomy:9606+AND+reviewed:yes PPT1], [http://www.uniprot.org/uniprot/?query=gene:APP+AND+taxonomy:9606+AND+reviewed:yes APP], [http://www.uniprot.org/uniprot/?query=gene:SYNGAP1+AND+taxonomy:9606+AND+reviewed:yes SYNGAP1]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0030730</td><td>sequestering of triglyceride</td><td>[http://www.uniprot.org/uniprot/?query=gene:IL1B+AND+taxonomy:9606+AND+reviewed:yes IL1B], [http://www.uniprot.org/uniprot/?query=gene:TNF+AND+taxonomy:9606+AND+reviewed:yes TNF], [http://www.uniprot.org/uniprot/?query=gene:ENPP1+AND+taxonomy:9606+AND+reviewed:yes ENPP1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0032119</td><td>sequestering of zinc ion</td><td>[http://www.uniprot.org/uniprot/?query=gene:S100A9+AND+taxonomy:9606+AND+reviewed:yes S100A9], [http://www.uniprot.org/uniprot/?query=gene:S100A8+AND+taxonomy:9606+AND+reviewed:yes S100A8], [http://www.uniprot.org/uniprot/?query=gene:SLC30A8+AND+taxonomy:9606+AND+reviewed:yes SLC30A8], [http://www.uniprot.org/uniprot/?query=gene:SLC30A7+AND+taxonomy:9606+AND+reviewed:yes SLC30A7]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0051208</td><td>sequestering of calcium ion</td><td>[http://www.uniprot.org/uniprot/?query=gene:ATP7B+AND+taxonomy:9606+AND+reviewed:yes ATP7B], [http://www.uniprot.org/uniprot/?query=gene:CALR+AND+taxonomy:9606+AND+reviewed:yes CALR], [http://www.uniprot.org/uniprot/?query=gene:CASQ2+AND+taxonomy:9606+AND+reviewed:yes CASQ2], [http://www.uniprot.org/uniprot/?query=gene:HSP90B1+AND+taxonomy:9606+AND+reviewed:yes HSP90B1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0035565</td><td>regulation of pronephros size</td><td>[http://www.uniprot.org/uniprot/?query=gene:HNF1B+AND+taxonomy:9606+AND+reviewed:yes HNF1B], [http://www.uniprot.org/uniprot/?query=gene:HNF1A+AND+taxonomy:9606+AND+reviewed:yes HNF1A]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:0035566</td><td>regulation of metanephros size</td><td>[http://www.uniprot.org/uniprot/?query=gene:PAX2+AND+taxonomy:9606+AND+reviewed:yes PAX2], [http://www.uniprot.org/uniprot/?query=gene:AGTR2+AND+taxonomy:9606+AND+reviewed:yes AGTR2]</td></tr>
 
<tr class="s1"><td>3</td><td>GO:0040030</td><td>regulation of molecular function, epigenetic</td><td>[http://www.uniprot.org/uniprot/?query=gene:ASIP+AND+taxonomy:9606+AND+reviewed:yes ASIP], [http://www.uniprot.org/uniprot/?query=gene:CTCF+AND+taxonomy:9606+AND+reviewed:yes CTCF]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0051100</td><td>negative regulation of binding</td><td>[http://www.uniprot.org/uniprot/?query=gene:CYP2D6+AND+taxonomy:9606+AND+reviewed:yes CYP2D6], [http://www.uniprot.org/uniprot/?query=gene:YBX2+AND+taxonomy:9606+AND+reviewed:yes YBX2], [http://www.uniprot.org/uniprot/?query=gene:P2RY1+AND+taxonomy:9606+AND+reviewed:yes P2RY1]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0035562</td><td>negative regulation of chromatin binding</td><td>[http://www.uniprot.org/uniprot/?query=gene:TDG+AND+taxonomy:9606+AND+reviewed:yes TDG], [http://www.uniprot.org/uniprot/?query=gene:WAPAL+AND+taxonomy:9606+AND+reviewed:yes WAPAL], [http://www.uniprot.org/uniprot/?query=gene:MEPCE+AND+taxonomy:9606+AND+reviewed:yes MEPCE], [http://www.uniprot.org/uniprot/?query=gene:SENP2+AND+taxonomy:9606+AND+reviewed:yes SENP2]</td></tr>
 
<tr class="s2"><td>5</td><td>GO:1901877</td><td>negative regulation of calcium ion binding</td><td>[http://www.uniprot.org/uniprot/?query=gene:SLN+AND+taxonomy:9606+AND+reviewed:yes SLN], [http://www.uniprot.org/uniprot/?query=gene:PLN+AND+taxonomy:9606+AND+reviewed:yes PLN]</td></tr>
 
<tr class="s1"><td>5</td><td>GO:0001845</td><td>phagolysosome assembly</td><td>[http://www.uniprot.org/uniprot/?query=gene:P2RX7+AND+taxonomy:9606+AND+reviewed:yes P2RX7], [http://www.uniprot.org/uniprot/?query=gene:SRPX+AND+taxonomy:9606+AND+reviewed:yes SRPX], [http://www.uniprot.org/uniprot/?query=gene:CORO1A+AND+taxonomy:9606+AND+reviewed:yes CORO1A], [http://www.uniprot.org/uniprot/?query=gene:MYO7A+AND+taxonomy:9606+AND+reviewed:yes MYO7A]</td></tr>
 
<tr class="s2"><td>4</td><td>GO:0010324</td><td>membrane invagination</td><td>[http://www.uniprot.org/uniprot/?query=gene:FCHO2+AND+taxonomy:9606+AND+reviewed:yes FCHO2], [http://www.uniprot.org/uniprot/?query=gene:FNBP1L+AND+taxonomy:9606+AND+reviewed:yes FNBP1L]</td></tr>
 
<tr class="s1"><td>4</td><td>GO:0016557</td><td>peroxisome membrane biogenesis</td><td>[http://www.uniprot.org/uniprot/?query=gene:PEX11A+AND+taxonomy:9606+AND+reviewed:yes PEX11A], [http://www.uniprot.org/uniprot/?query=gene:PEX19+AND+taxonomy:9606+AND+reviewed:yes PEX19], [http://www.uniprot.org/uniprot/?query=gene:PEX16+AND+taxonomy:9606+AND+reviewed:yes PEX16], [http://www.uniprot.org/uniprot/?query=gene:PEX3+AND+taxonomy:9606+AND+reviewed:yes PEX3]</td></tr>
 
</table>
 
  
 
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==Resources==
 
==Resources==

Latest revision as of 23:56, 26 November 2016

Constructing the GO term table



 

Extracting gene functions from GO and GOA

The table of selected biological process GO terms a starting point for system definition and gene selection.


 

The objective of selecting GO terms from the ontology is to find nodes that have a small number of genes associated to them (or their children). If the number of annotated genes is too small, not enough may be known about the system to usefully model it. If the number is too large, modelling the system will be too time consuming for the scope of a class project. It is also highly likely that the system should actually be broken down into subsystems, which ought to be modelled individually. I have chosen GO terms with from three to five annotated genes as a cutoff that seems workable.

Roughly, this selection works as follows:

1. Retrieve the ontology terms, and the list of annotated human genes from the database.
2. Remove all terms that are not in the biological process ontology.
3. Associate all human genes with their respective terms.
4. Remove all terms that are leafs (no children) AND have no genes annotated.
5. For each term, find all descendants.
6. Of all descendants, collect all annotated genes.
7. Make the list of genes unique. This is important since there may be more than one path to a gene and we don't want to double count it.
8. Store the number of genes associated to a term and its descendants.
9. Select terms that have 3 to 5 associated genes.
10. Remove terms that contain certain keywords that may make the process less suitable for our purposes, such as "development", "morphogenesis", "behavior".
11. Write the remaining terms into a Wiki table format, with links to GO terms and genes.

Details below.


 

Creation of the Process Table

The Process Table was created in the following steps:

1. I downloaded the most recent version of goa_human.gaf from the GOA repository at the EBI, released on November 22. 2016. The file contains gene names and GO terms - here is one line of the contents (selected columns):
UniProtID  GeneSymbol  GOtermID    Reference       EvidenceCode  Description                taxID
Q14209     E2F2        GO:0051726  GO_REF:0000019  IEA	          Transcription factor E2F2  taxon:9606		
2. I downloaded the GO term file go-basic.obo from its repository at GO - the Gene Ontology Consortium. It contains the actual ontology terms (45,896 terms), they look like this (some information omitted).
[Term]
id: GO:0051726
name: regulation of cell cycle
namespace: biological_process
def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb]
is_a: GO:0050794 ! regulation of cellular process
relationship: regulates GO:0007049 ! cell cycle
Note the is_a relationship that points to the parent term, GO:0050794, of which GO:0051726 is a specialization. This means: the terms have parent-associations listed with them, but don't list child terms. This means we can go up to the root from each term, but we can't descend. We need to record the child terms for each node, to be able to navigate both up and down through the ontology.
3. Open this file in R and read all the terms that are labelled as namespace: biological_process into a data frame storing ID, name, definition, and parent term IDs. These are 29,309 terms. Then add each term ID to its parent terms as a child term.
4. Open the human GOA file and read all gene annotations into a data frame. These are 392,942. That's a lot - we expect at least three annotations for each of the 19,225 genes that GOA currently contains, one for each ontology, but we find on average 20 annotations. Next, add each gene symbol to the term data frame, if the annotation's GO ID is in our set.
5. Next, remove all terms that are leaves (i.e. they don't have children), AND have no annotated genes. These are terms that might be specific to fungi, prokaryotes, viruses or similar. Since our goal is to count the number of genes associated with each term, those can't contribute since their own count is zero. Deleting those nodes obviously creates new leaves in the ontology, so this process has to be iterated, until no more nodes can be removed. This deletes 11,733 terms from the ontology.
6. We need a function that finds all descendants of a term. In order to find and visit all descendants, start from a term and put its child(ren) into a queue. While the queue is not empty, remove the first ID from the queue, and add those of its children to the queue that we haven't visited before.
7. For each term, count all genes that are associated to it or to any of its descendants. The root term, GO:0008150 has 17,030 associated genes.
8. Next, select all terms that have from three to five associated genes AND contain none of a list of keywords. These keywords include: "proliferation", "development", "morphogenesis", "regression", "induction", "maturation", "formation", "growth", "*bolic process", "biosynthetic process", and "behavior". I feel that even though the GO terms may be manageable, the actual system would likely contain an unwieldy number of genes. I also removed all "positive regulation of ...", and "negative regulation of ..." terms. These always have a parent term: "regulation of ..." and that term would be the right one to consider.
9. Finally, the 1,224 selected terms were written into a table in an editable Wiki code format, including links to GO and UniProt.


 

How to use the table to adopt a function and define a "system" for the project

 

I have randomly chosen a term – GO:0001845 (phagolysosome assembly) – to illustrate the process:


 
1. Browse the table and find a function that interests you. It's very diverse and will give you a good first sense of the complexity of functions in the cell and our state of knowledge about them. Have a look at the term information. There is probably a link to an associated "GONUTS" page with more information.
2. Look at the function information available when you follow the links of the annotated genes to UniProt. Most of these genes have more than one GO term annotated to them, and taken together, these GO terms shed more light on how the "system" is more and different than its annotated GO terms. For example from the genes in GO:0001845 let's look at "SRPX". This gene codes for P78539 (SRPX). Here are the annotated processes in which this protein participates:
Just looking at these processes tells me a lot. The annotation is for one protein, but it is implied in several aspects of biology. Some of them are causal to others, and some of them are generalizations. Here, the phagolysosome needs to be assembled in order to function. Once it has been made, this enables stress response, and contact inhibition, likely via apoptotic pathways and autophagy. This phagolysosome assembly sounds like a good system to work on. But is the term too broad, or too narrow? Could I find a better name for it?
3. Follow the link to the phagolysosome assembly GOterm page at QuickGO, and explore the tabs that contain the Ancestor Chart and the Child Terms:
Relationship
to GO:0001845
Child Term Child Term Name
Part of GO:0090384 phagosome-lysosome docking
Part of GO:0090385 phagosome-lysosome fusion
Is a GO:0090387 phagolysosome assembly involved in apoptotic cell clearance


 

Explore how many proteins are annotated to this term. There are probably VERY many - so set a taxon filter on this table (taxon: 9606) to view only human proteins.


 

As a result of my first exploration I see:

  • There are probably around 20 proteins that I'll need to cnsider as system components;
  • most of them are RAB genes which have a reasonably well understood function. It will be interesting to find out how this function enables the process;
  • The mechanism of this system will likely include proteins that are specific to this process, and others that are involved in membrane fusion in a general sense and are recruited to this specific task.

This looks like an good starting point to define the components of a system. For now, I would be oK with calling it the "Phagosome / Lysosome Fusion System".


 

Considerations for choosing a system

Keep your systems simple. I would avoid choosing systems/processes that integrate sensory, nervous, hormonal and cellular components. This may become too complex. Narrowing it down, to a manageable "subsystem" is a valuable exercise in itself. Such a system may implement

  • integrating input,
  • transmitting input signals to their effectors,
  • regulating the process,
  • providing resources,
  • defining setpoints,
  • assembling or disassembling the system,
  • mediating interactions with other systems,
  • or similar...

Keep your systems manageable. When considering how many genes are associated with a system, check the taxon section of the relevant GO terms' statistic on QuickGO. The number of genes involved in the process in humans is likely as large as the largest number for ANY species - although many of the human genes may not have been annotated for that process (yet). For example, if the mouse (mus musculus) has 20 annotated genes and humans have only two, that probably does not mean humans can achieve with only two genes that for which the mouse needs twenty. In this situation, looking for orthologues of mouse genes should lead you to human candidate genes. But as a corollary, if the mouse has many, many genes annotated, that particular process might not be so suitable for this project after all.


 

Resources