Difference between revisions of "Reference alignment for Mbp1 orthologues (MUSCLE)"

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m (Boris moved page All Mbp1 MUSCLE annotated to Reference alignment for Mbp1 orthologues (MUSCLE) without leaving a redirect)
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Revision as of 17:14, 1 December 2014

Result of MUSCLE alignment of all Mbp1 protein orthologues. Default parameters, CLUSTAL ALN format. Output order of rows kept same as input order, i.e. according to sequence similarity of adjacent rows as represented in the CLUSTAL guide tree. Mbp1-based annotations have been added to the computed alignment by hand.

Annotation Keys:

  • * Proposed binding region
  • + positively charged residues, oriented for possible DNA binding interactions
  • - negatively charged residues, oriented for possible DNA binding interactions
  • E beta strand
  • H alpha helix
  • t beta turn
  • x Low complexity region
  • C Coiled coil regions predicted by Coils2 program
MUSCLE (3.6) multiple sequence alignment

Mbp1_ASPFU      ------------------------------------------------------------
Mbp1_ASPNI      ------------------------------------------------------------
Mbp1_ASPTE      ------------------------------------------------------------
Mbp1_CRYNE      --MEPPSNPIQPPVTPSHHSLLSAISPALSEQTPAPIHTLPPHLRPSIPQPHIAPPRPSS
Mbp1_GIBZE      ---------------------MSQQSQ---------------------------------
Mbp1_MAGGR      MASTVAGNSFVSQQHPGNLHSANLQSQSQGFRRQNSTSSVPSTASFDPPNGSIANTGSQK
Mbp1_NEUCR      -------------MQPPQLGGASQQSQ---------------------------------
Mbp1_CANAL      ------------------------------------------------------------
Mbp1_DEBHA      ------------------------------------------------------------
Mbp1_PICST      ------------------------------------------------------------
Mbp1_CANGL      ------------------------------------------------------------
Mbp1_SACCE      ------------------------------------------------------------
Mbp1_EREGO      ------------------------------------------------------------
Mbp1_KLULA      ------------------------------------------------------------
Mbp1_YARLI      ------------------------------------------------------------
Mbp1_COPCI      ------------------------------------------------------------
Mbp1_USTMA      ------------------------------------------------------------
Mbp1_SCHPO      ------------------------------------------------------------
                                                                            

Mbp1_ASPFU      ------------------------------------------------------------
Mbp1_ASPNI      -------------------------------------MAAVDF-----------SNVYSA
Mbp1_ASPTE      -------------------------------------MAGVDF-----------SKIYSA
Mbp1_CRYNE      VQPTMEEQQRMHHIQQHQQ-QQHFQQQQNDENVFGSVMGAPGHVPGHEAPMSTQPKVYAS
Mbp1_GIBZE      -----------SGMGNSFR---------------GGYNGDPDN-----------SGIYSA
Mbp1_MAGGR      HHPMSSQQSQPPASQQSFSMSQTGSQPQPSQSSFRSYSDQNVPQQPQEA-----SPIYTA
Mbp1_NEUCR      -----------PSSQQSFSMSQS------SQSVYRQYTDPPNRLHNDHAV----PTIYSA
Mbp1_CANAL      ----------------------------------------MSD-----------SQIYSA
Mbp1_DEBHA      ---------------------------------------MADN-----------TQIYSA
Mbp1_PICST      ----------------------------------------MTS-----------TQIYSA
Mbp1_CANGL      -----------------------------------------MS-----------NQIYSA
Mbp1_SACCE      -----------------------------------------MS-----------NQIYSA
Mbp1_EREGO      ----------------------------------MSAGSAVSA-----------TQIYSA
Mbp1_KLULA      ----------------------------------------MSS-----------NQIYSA
Mbp1_YARLI      ------------------------------------------------------MSIYKA
Mbp1_COPCI      ----------------------------------------MPE-----------AQIFKA
Mbp1_USTMA      ---------------------------------------MSGD-----------KTIFKA
Mbp1_SCHPO      --------------------------------------MAPRS-----------SAVHVA
1MB1 3D                                                  ---------------EEEE
                                                                            

Mbp1_ASPFU      -----------------MRRRGDDWINATHILKVAGFDKPARTRILEREVQKGTHEKVQG
Mbp1_ASPNI      TYSSVPVYEFKIGTDSVMRRRSDDWINATHILKVAGFDKPARTRILEREVQKGVHEKVQG
Mbp1_ASPTE      TYSSVPVYEFKIEGDSVMRRRADDWINATHILKVAGFDKPARTRILEREVQKGVHEKVQG
Mbp1_CRYNE      VYSGVPVFEAMIRGISVMRRASDSWVNATQILKVAGVHKSARTKILEKEVLNGIHEKIQG
Mbp1_GIBZE      SYSGVDVYEMEVNNIAVMRRRNDSWLNATQILKVAGVDKGKRTKILEKEIQTGEHEKVQG
Mbp1_MAGGR      VYSNVEVYEFEVNGVAVMKRIGDSKLNATQILKVAGVEKGKRTKILEKEIQTGEHEKVQG
Mbp1_NEUCR      TYSGVGVYEMEVNNVAVMRRQKDGWVNATQILKVANIDKGRRTKILEKEIQIGEHEKVQG
Mbp1_CANAL      TYSNVPAFEFVTSEGPIMRRKKDSWINATHILKIAKFPKAKRTRILEKDVQTGIHEKVQG
Mbp1_DEBHA      TYSNVPVFEFVTLEGPIMRRKLDSWINATHILKIAKFPKAKRTRILEKDVQTGVHEKVQG
Mbp1_PICST      TYSNVPVFEYVTSEGPIMRRKSDSWINATHILKIAKFPKAKRTRILEKDVQTGVHEKVQG
Mbp1_CANGL      KYSGVDVYEFIHPTGSIMKRKNDGWVNATHILKAANFAKAKRTRILEKEVLKEMHEKVQG
Mbp1_SACCE      RYSGVDVYEFIHSTGSIMKRKKDDWVNATHILKAANFAKAKRTRILEKEVLKETHEKVQG
Mbp1_EREGO      KYSGVEVYEFLHPTGSIMKRKADDWVNATHILKAAKFAKAKRTRILEKEVIKDTHEKVQG
Mbp1_KLULA      KYSGVDVYEFIHPTGSIMKRKADNWVNATHILKAAKFPKAKRTRILEKEVITDTHEKVQG
Mbp1_YARLI      TYSGVPVYEFQCKNVAVMRRKSDGWVNATHILKVAGFDKPQRTRILEKEVQKGVHEKVQG
Mbp1_COPCI      TYSGIPVYEMMCKGVAVMRRRSDSWLNATQILKVAGFDKPQRTRVLEREVQKGEHEKVQG
Mbp1_USTMA      TYSGVPVYECIINNVAVMRRRSDDWLNATQILKVVGLDKPQRTRVLEREIQKGIHEKVQG
Mbp1_SCHPO      VYSGVEVYECFIKGVSVMRRRRDSWLNATQILKVADFDKPQRTRVLERQVQIGAHEKVQG
                                 *.*  *..:***:*** . . *  **.:**.::    ***:**
1MB1 3D         Ett-EEEEEEEEt-EEEEEEtt---EEHHHHHHH----HHHHHHHHhhhHHH---EEE--
Annotation                                               **+**-+******+*+***

Mbp1_ASPFU      GYGKYQGTWIPLHEGRLLAERNNIIDKLRPIFDYVAG-DH-----TPPPAPKHTSAASSR
Mbp1_ASPNI      GYGKYQGTWIPLQEGRQLAERNNILDKLLPIFDYVAG-DR-----SPPPAPKHTSAASKP
Mbp1_ASPTE      GYGKYQGTWIPLPEGRLLAERNNIIDKLRPIFDYVAG-DR-----SPPPAPKHTSAASKP
Mbp1_CRYNE      GYGKYQGTWVPLDRGRDLAEQYGVGSYLSSVFDFVPS-AS-----VIAALPVIRTGTPDR
Mbp1_GIBZE      GYGKYQGTWIKFERGLQVCRQYGVEELLRPLLTYDMGQDGGVAGRGDLNTPTKEQAMAAQ
Mbp1_MAGGR      GYGKYQGTWIKYERALEVCRQYGVEELLRPLLEYNRNPDG-SVSQANLNTPTKEQAMAAQ
Mbp1_NEUCR      GYGKYQGTWIPFERGLEVCRQYGVEELLSKLLTHNRG-QE--GETGNVDTPTKEQAMAAQ
Mbp1_CANAL      GYGKYQGTYVPLDLGAAIARNFGVYDVLKPIFEFQYI-EG--QTEVPPPAPKHNHASALN
Mbp1_DEBHA      GYGKYQGTYVPLDLGADIAKNFGVFDSLRPIFEFTYV-EG--KSETPPPAPKHSHASASN
Mbp1_PICST      GYGKYQGTYVPLELGRDIAKNFGVFDILKPIFDFKYI-EG--KSETPPPAPKHNHASALN
Mbp1_CANGL      GFGKYQGTWVPLNIAINLAEKFDVYQDLKPLFDFSEE-NG---DAAPPPAPKHHHASKAS
Mbp1_SACCE      GFGKYQGTWVPLNIAKQLAEKFSVYDQLKPLFDFTQT-DG---SASPPPAPKHHHASKVD
Mbp1_EREGO      GFGKYQGTWVPLDIARRLAQKFEVLEELRPLFDFTRR-DG---SESPPQAPKHHHASRAD
Mbp1_KLULA      GFGKYQGTWIPLELASKLAEKFEVLDELKPLFDFTQQ-EG---SASPPQAPKHHHASRSD
Mbp1_YARLI      GYGKYQGTWVPLERAREIATLYDVDSHLAPIFNYDDE-DG-----SPPPAPKHRPNLERK
Mbp1_COPCI      GYGKYQGTWIPLERGMQLAKQYNCEHLLRPIIEFTPA-AK-----SPPLAPKHLVATAGN
Mbp1_USTMA      GYGKYQGTWIPLDVAIELAERYNIQGLLQPITSYVPSAAD-----SPPPAPKHTISTSNR
Mbp1_SCHPO      GYGKYQGTWVPFQRGVDLATKYKVDGIMSPILSLDID-EG------KAIAPKKKQTKQKK
                *:******::    .  :.        :  :                   *         
1MB1 3D         --tt--EEEE-HHHHHHHHHH---HHHHtt-
Annotation      ******                                     xxxxxxxxxxxxxx

Mbp1_ASPFU      PR---------------------------------------------ASKKKAVNE----
Mbp1_ASPNI      RAPKI--------------------------------------------NKRVVKE----
Mbp1_ASPTE      RVSKA------------------------------------------AANRRVANE----
Mbp1_CRYNE      SGQQT--------PSGLPGHPNQ-----RVISPFANHGQTTPHMPPPQFIHQGNEQ----
Mbp1_GIBZE      RKRLY--------NQSADGRANG-----VSGTFFKNISTTASHAVAAISKARFDSP-G--
Mbp1_MAGGR      RKKMY--------NSGADSRNNN-----GGGTFFKNISQTAHSAMTAISKARFDSP----
Mbp1_NEUCR      RKRMY--------NASSQENRGI----GSTGTFFKNISSTASTAVAAISKARFDSP----
Mbp1_CANAL      VAKRQ--------ASLLKKQKEK---QVQPTLSDTSFGSSTSVPPTTVPKKRGRPK----
Mbp1_DEBHA      VAKRQ--------SSVNNSSGDA---NSLNKTSHARKTKSMTSLSGEPPKKRGRPK----
Mbp1_PICST      IAKRS--------AVPQQAKKSR---------------TASATLTGEPPKKRGRPK----
Mbp1_CANGL      SAKAKKAGRSVSSPAMNDSKTRASTRKANTPSSNDITSDSGAVVNPVVTRRRGRPPNSTL
Mbp1_SACCE      RKKAI--------RSASTSAIMETKRNNKKAEENQFQSSKILGNPTAAPRKRGRPVGSTR
Mbp1_EREGO      SARKR--------TTKSPPLPHG--------------------QLDALPKRRGRPPRA--
Mbp1_KLULA      STRKK--------ATKSASVPSGKVSEKASSQQQQPVSQQQQQQPGSAPKRRGRPP----
Mbp1_YARLI      KRTKV--------TG--------------------------------SPLVRQPSR----
Mbp1_COPCI      R-----------------------------------------------PVADGVGE----
Mbp1_USTMA      SKKII----------------------------------------PADPGALGRSR----
Mbp1_SCHPO      PS---------------------------------------------VRGRRGRKP----
                                                                            

Mbp1_ASPFU      -------------------------------------------------------QVFSA
Mbp1_ASPNI      -------------------------------------------------------DVFSA
Mbp1_ASPTE      -------------------------------------------------------EVFSA
Mbp1_CRYNE      ---MMNLPPHPSSLAYPTQPKPYF---------SMPLQHTVGPQYDERHEGMTMTPTMSM
Mbp1_GIBZE      PRSSRNGASRTASFSRQASMQNGD---DFPSNSQQSFASDYGQQVDSAYSTQQANNSVQM
Mbp1_MAGGR      GPRGRNGPTRAPSFQRQLSTQSIDDFHGGNSQASNFAENFPPQDVNMAFSAGSEPQPGGL
Mbp1_NEUCR      APRNRSGPSRAPSFNRQSSMQDVADFPNSQQSLVSTEYATQTQNADSGFGSQTTQPLAGD
Mbp1_CANAL      ----RATLSATPSLQRSDTT-------PINKSLIDFNANDHSAKSSFIGVVPSFARNDTE
Mbp1_DEBHA      --RVPMQNNIEPSLQHTDTTPITT--------IPESGPSIGTFNNKKSLGHPTLTRQDTE
Mbp1_PICST      ---RVPMTAAEPVLKHSDTTP------------INGPMNSINGPLEGSFTHPALSRHDTE
Mbp1_CANGL      TNKRKLGTGLQRSQSEMAFLKPEI------------------PNDLNSNDIANIQQVNSG
Mbp1_SACCE      GSRRKLGVNLQRSQSDMGFPRPAI---PNSSISTTQLPSIRSTMGPQSPTLGILEEERHD
Mbp1_EREGO      RKLSDVANVAGQTQVYSDFPRPSI---PVSSISSNQLPSLQSTLHRSI-------SIEHN
Mbp1_KLULA      --RNKATVTLQRSQSEMVFPKPSI---------PSSSIQSTKLPSLQPQFGRSATSLSPI
Mbp1_YARLI      --------------------------------------------------METLTQSTGS
Mbp1_COPCI      ---------------------------------------------------------ESD
Mbp1_USTMA      --------------------------------------------------RATSIETESE
Mbp1_SCHPO      --------------------------------------------------SSLSSSTLHS
                                                                            

Mbp1_ASPFU      AKPIRNMGPPSFPHEQFEINPGYDDNESI-------------------------------
Mbp1_ASPNI      VNHHRSMGPPSFHHEHYDVNTGLDEDESI-------------------------------
Mbp1_ASPTE      VKPHRPMGPPSFTHEQYEMHSGFDEDESI-------------------------------
Mbp1_CRYNE      DGLAPPADIARMGFPYNPSDIYIDQYGQPHA------TYQASPYGKESGHPSKRQRSDAE
Mbp1_GIBZE      TEPDPPRKRQRVTMTPAESFNGYGQNVDM-------------------------------
Mbp1_MAGGR      NGTEPPRKRQRMDMTPANSFGAYANNSQMQ------------------------------
Mbp1_NEUCR      GLEQPPRKRQR-VLTPARSFGGQTPGHQPL----------------------------DP
Mbp1_CANAL      QDALQIMTNNMNLRQEDLASVETDDDEEYH----------NGSRGDGLQNDSFTTKRRKY
Mbp1_DEBHA      QDALQIMASNMSANQEDLELADKSSDEDMG--------------NRTPIDTQDENIHHED
Mbp1_PICST      QDALQVMAGNMNIKNEDLELVDSDDDDDVV-------------KKRRNGVNVALSLDSQV
Mbp1_CANGL      DLLRNEKIQKNIQLKEIDLDDGLSSDVEVQETD----TFQPNHQSSLLGAEGHELRNNDS
Mbp1_SACCE      SRQQQPQQNNSAQFKEIDLEDGLSSDVEPSQQLQQVFNQNTGFVPQQQSSLIQTQQTESM
Mbp1_EREGO      RNKAPPQPNHK--YEELDIEDGLSSDIETSI------CTNMVYAGHSNARLPMNTSLLPD
Mbp1_KLULA      MDVKSPLDQASPQFKELDIEDGLSSDVEPN-------------SIMGTKHEDNTHLMNTK
Mbp1_YARLI      TMGGTPQHSRQSSLSQLAQSYGLDDSDHV-------------------------------
Mbp1_COPCI      HDTHSLRGSEDGSMTPSPSEASSSSRTP--------------------------------
Mbp1_USTMA      VIGAAPNNVSEGSMSPSPSDISSSSRTP--------------------------------
Mbp1_SCHPO      VNEKQPNSSISPTIESSMNKVNLPGAEEQV------------------------------
Annotation        xxxxxx                                     xxxxxxxxxxxxxxx
                                                                            

Mbp1_ASPFU      -----EQATLESSSMAADEEMM----------SMSQHGAYSRKRKREMNEVTAMSISEQE
Mbp1_ASPNI      -----EQATLESSSMIADEDMI----------SMSQNGPYSSRKRKRGINEVAAMSLSEQ
Mbp1_ASPTE      -----EQATLESSSMVADEDMM----------TMSQSGAYSRKRKRGNDVPTMSIGEQEH
Mbp1_CRYNE      GSYIESGAAVQQHVEQDEEADDGLDNDSTASDDARDPPPLPSSMLLPHKPIRPKATPANG
Mbp1_GIBZE      -----YAAAYPGSPTEPNESFM---YTQS---AIHDRSPIEEG---NGPLEPLPYEMSPD
Mbp1_MAGGR      ----AYADAFPGSPTEPNDSFI---YTQH---AAANDTLLQQQHDQQTPLQPLPYEQSVE
Mbp1_NEUCR      FNAGNIANGDSGSPTEPSNSFN---YDQVT--ANDGDASYALG-----PLRPLPYENNAD
Mbp1_CANAL      PGGMTNGNGLESQADLLTSKELFGVSRTSFEKRANQQHNHYSPLQPYHQPSISLSQENQI
Mbp1_DEBHA      NDELMTGRELFGTPRNSFERIVQSHNQSHNHLNGSIHDPYGLLQYHHHTSHTHSMRDDAI
Mbp1_PICST      GDDLLGSKELFGASRGSFERVI---HNHNSNNNGHLQSHDPYSFSQYHQPSVSSQNETDV
Mbp1_CANGL      PLSPSSSSSLPTSPANLNDSNP---FDQRL--GGGGTSPIISLIPRYSVQSRPQVTDINE
Mbp1_SACCE      ATSVSSSPSLPTSPGDFADSNP---FEERF--PGGGTSPIISMIPRYPVTSRPQTSDIND
Mbp1_EREGO      KEEPGLSSSLPSSPSEFSAPMV---FDTQR--MGSATSPLGSMLPRYMAPSRPRTSELDQ
Mbp1_KLULA      DEPVSSSSSLPSSPSEFSQSVA-------FGSRSNMQTPLQLNGTTSMNMILPKFSSSQN
Mbp1_YARLI      -------TPSPPTVADDSSDFM----------SDEEVDRQMGNYPRPMMAKPKPIQVRDP
Mbp1_COPCI      ------------SPIHSPGTYH----------SNGLDGPSSGGRNRYRQSNDRYDEDDDA
Mbp1_USTMA      -------SPLPADRAHPLH-------------ANHALAGYNGRDANNHAR----------
Mbp1_SCHPO      -----SATPLPASPNALLSP------------NDNTIKPVEELGMLEAPLDK--------
Annotation      xxxxxxxxxxxxx
                                                                            

Mbp1_ASPFU      HIL--------YGDQLLDYFMTVGDAP----EATRIPPPQ--PP---ANFQVDRPIDDSG
Mbp1_ASPNI      EHIL-------YGDQLLDYFMTVGDAP----EATRIPPPQ--PP---ANFQVDRPIDDSG
Mbp1_ASPTE      IL---------YGDQLLDYFMTVGDAP----EATRVPPPE--PP---VNFQVDRPIDDSG
Mbp1_CRYNE      R----------IKSRLVQIFNVEG-------QVNLRSVFGLAPD-QLPNFDIDMVIDDQG
Mbp1_GIBZE      VEN--------KRNVLMGLFLETTGTD----PTKNDTLRGFTP------LELDMPIDLQS
Mbp1_MAGGR      AEN--------KRSMLMSIFMNDGMSE----QARVDTLRQIHP------RDLDMPIDSQC
Mbp1_NEUCR      AEA--------KRGMLMGLFMDANGPE----EAIQAALCNVSP------QELDSPIDTQS
Mbp1_CANAL      YSD--------YFQSLLSYFLDDNNK-----IRSPIPDSLLSPPLPLSKIHIYQTIDSDG
Mbp1_DEBHA      YAD--------YFTNLLNYFLEDGNNKVRSTQESNIPDKILNPPQPLSKINITQPVDNEG
Mbp1_PICST      VYSD-------YFSSLLTYFLDDSKI-----RSNNIPEKLLNPPQPISKIQINQPIDNEG
Mbp1_CANGL      KVND-------YLTKLVDYFISNEMK-----SNKTVPQELLHPP-TQSAPFIDAPIDPEL
Mbp1_SACCE      KVNK-------YLSKLVDYFISNEMK-----SNKSLPQVLLHPP-PHSAPYIDAPIDPEL
Mbp1_EREGO      KANE-------YLSKLVDYFINCEVQ-----NNGAVPMELLNPP--HSSPCIDSWIDSEH
Mbp1_KLULA      GPSDSNQRANEYLSKLVNYFISNDTQ-----NESEIPMELLNPP-LHCSPFIDTWIDPEH
Mbp1_YARLI      KDL--------YTNDLLNYFVSA--------DDEKIPAFLENPP---AEFDVHRPIDEEG
Mbp1_COPCI      SRHNGMGDPRSYGDQILEYFIS---------DTNQIPPILITPP---PDFDPNMAIDDDG
Mbp1_USTMA      -----------YADIILDYFVT---------ENTTVPSLLINPP---PDFNPDMSIDDDE
Mbp1_SCHPO      -----------YEESLLDFFLHP--------EEGRIPSFLYSPP---PDFQVNSVIDDDG
                               ::  *                .     *            :* . 
Ankyrin 3D                                                           --t----

Mbp1_ASPFU      NTALHWACAMGDLEIVKDLLRRGA---NIKALSVHEETPLVRAVLFTNNYEKRTFPALLD
Mbp1_ASPNI      NTALHWACAMGDLEIVKDLLRRGA---DMKALSIHEETPLVRAVLFTNNYEKRTFPALLD
Mbp1_ASPTE      NTALHWACAMGDLEIVRDLLRRGA---DVKALSVHEETPLVRAVLFTNNYEKRTFPALLE
Mbp1_CRYNE      HSALHWACALARLSIVQQLIELGA---DIHRGNYAGETPLIRAVLTSNHAEAGSFTDLLH
Mbp1_GIBZE      HTALHWAATLARMPLLRALIAAGA---SPARVNGSGETALMRACLVTNSQDHNSFPDLLE
Mbp1_MAGGR      HTALHWAATLSRMTILRRLIEAGA---SPFRVNTSGETPLMRACIVTNSHDNDSMPAILD
Mbp1_NEUCR      HTALHWAATLSRMPLLRALIHAGA---NPWRVNACGETALMRACTVTNSMENNTFPELLD
Mbp1_CANAL      NTIFHWACSMGNLNMVEFLLKTFTHSLNPDVRNNNGETPLMFMVKFNNSFQLRNFPLILD
Mbp1_DEBHA      NTIFHWACSMANNGMIEFLLATFESFLNSDLKNNRGETPLMFLVKFSNSYQLKNFPTLLD
Mbp1_PICST      NTIFHWACSMANISSIEFLLVTFQ--ISPDIRNNKGETPLMFLVKFVNSFQLRNFPSILQ
Mbp1_CANGL      HTAFHWACSMGNLPIVEALYETGT---NIRAANANGQTPLMRSAMFHNSYTRRSFPRIFE
Mbp1_SACCE      HTAFHWACSMGNLPIAEALYEAGT---SIRSTNSQGQTPLMRSSLFHNSYTRRTFPRIFQ
Mbp1_EREGO      HTAFHWACAMGTLPIVEALLQAGA---SPRALNQAGETPLMRASLVHNSYTKRTYPRIFQ
Mbp1_KLULA      HTAFHWACAMGTLPIVEALLKAGS---SIRSLNNVGETPLIRSSIFHNCYTKRTYPQIFE
Mbp1_YARLI      HTALHWACAMGHLRVIELLLKAGS---DVRATNMFGQTPLTRAIMFTNNYDRRTFPKVVD
Mbp1_COPCI      HTSLHWACAMGRIRIVKLLLSAGA---DIFKVNKAGQTALMRSVMFANNYDVRKFPELYE
Mbp1_USTMA      HTALHWACAMGRIRVVKLLLSAGA---DIFRVNSNQQTALMRATIFPNSLSS--FT----
Mbp1_SCHPO      HTSLHWACSMGHIEMIKLLLRANA---DIGVCNRLSQTPLMRSVIFTNNYDCQTFGQVLE
                :: :***.::.       *        .    .   :*.*       *            
Ankyrin 3D      HHHHHHH---HHHHHt-t--t-t-----t----t----HHHHHHHH---------HHHHH

Mbp1_ASPFU      LLLDTVSFRDWFGATIFHHISETTR-----------------SKGKWKSSRYYCEVLLDK
Mbp1_ASPNI      LLLDTISFRDWFGATLFHHIAQTTK-----------------SKGKWKSSRYYCEVALEK
Mbp1_ASPTE      LLLDTVSFRDWFGATLFHHIAETTR-----------------SKGKWKSSRYYCEVLLEK
Mbp1_CRYNE      LLSPSIRTLDHAYRTVLHHIALVAG-----------------VKGRVPAARTYMASVLEW
Mbp1_GIBZE      VLGGTIEARDHKGRTVLHHIAVTSA-----------------VKGRNAASRYYLESLLEW
Mbp1_MAGGR      ILGNTMEVRDSKERTVLHHIALTSA-----------------VSGRSAASRYYLQCLLGW
Mbp1_NEUCR      LLGCTLDVTDDKGRTVLHHIAVTSA-----------------VKGRHYASRYYLESLLEW
Mbp1_CANAL      LLKESVLLVDSNGKTVLHHIVDTDS-----------------KHKREKFAQYYLESLLEK
Mbp1_DEBHA      LLFDSILSIDNYGRTVLHHIALAANNLTSEGSINANTDIHTFKKNKERFARYYMECLFAK
Mbp1_PICST      MLLESILLVDKSGKTVLHHIALID------------------SEKKFRFARYYMETLFDK
Mbp1_CANGL      LLSETVFDIDSMGQTVLHHIVK--------------------RKSSTPSAIYYVNVLLSK
Mbp1_SACCE      LLHETVFDIDSQSQTVIHHIVK--------------------RKSTTPSAVYYLDVVLSK
Mbp1_EREGO      LLQDTVFDVDSRSQTVVHHIVK--------------------RKSNTPSALYYLDVLLSK
Mbp1_KLULA      ILKDTVFDLDAKSRNVIHRIVS--------------------RKSHTPSAVYYLDVVLSK
Mbp1_YARLI      ILQDTLFQVDGQGRTVLHHIAQH-------------------VSKSQSAAKYYVTILLSK
Mbp1_COPCI      LLHRSTLNIDNSNRTVFHHVVDVAM-----------------SKGKTHAARYYMETILTR
Mbp1_USTMA      ---DPSLNIDRNDRTVFHHVVDLAL-----------------SRGKPHAARYYMETMINR
Mbp1_SCHPO      LLQSTIYAVDTNGQSIFHHIVQSTS-----------------TPSKVAAAKYYLDCILEK
                    .    *    .:.*.:                             :  *    : .
Ankyrin 3D      HHHH-ttHHH-----HHHHHHH----------------------tH--HHHHHHHHH---

Mbp1_ASPFU      LHNT------------------------CSQDEIDLL----LSCQDSNGDTAALVAARNG
Mbp1_ASPNI      LRTT------------------------FSPEEVDLL----LSCQDSVGDTAVLVAARNG
Mbp1_ASPTE      LRAT------------------------CSAEEIDLL----LSCQDSNGDTAALVAARNG
Mbp1_CRYNE      VAREQQANNTH----SITNPPNPADRNELAPINLRTL----VDVQDVHGDTALNVAARVG
Mbp1_GIBZE      VVRQGSAPNSQ--NTQTNGNGPSNSQAASPKMGIARFMTEIVNAQDSVGDTALNIAARIG
Mbp1_MAGGR      VVRQGAANGGQLNSQTFNGGATVSQSQNATRLDLGRFMSEMLNAQDSAGDTALNIAARIG
Mbp1_NEUCR      VVRQGSAPSSQ---------ENGIGDRKGRRMGIARFMSEIVNAQDNSGDTALNVAARVG
Mbp1_CANAL      IVDERQEQGDS--------NGHAMEDDLTKDELVTKF----INHQDSDGNTAFHIAAHNL
Mbp1_DEBHA      IIEFQEIRDLQ-------EIENKKLSLSDKKELIAKF----INHQDIDGNTAFHIVAYNL
Mbp1_PICST      IIES------------LEDEEDFAKDPDNKKDLIAKF----INHQDSDGNTAFHICSHNL
Mbp1_CANGL      IKDI------------------------SPKYRIELL----LNTKDANGDTALHIAARNN
Mbp1_SACCE      IKDF------------------------SPQYRIELL----LNTQDKNGDTALHIASKNG
Mbp1_EREGO      LKDF------------------------SPQYRIETL----INAQDCKGSTPLHIAAMNR
Mbp1_KLULA      IKDF------------------------TPQYRIDVL----INQQDNDGNSPLHYAATNK
Mbp1_YARLI      ISEN------------------------HSLGVLSQF----MDTQNNEGDTALHILARSG
Mbp1_COPCI      LADY--------------------------PKELADV----INFQDEDGETALTMAARCR
Mbp1_USTMA      LADY--------------------------GDQLADI----LNFQDDEGETPLTMAARAR
Mbp1_SCHPO      LISI------------------------QPFENVVRL----VNLQDSNGDTSLLIAARNG
                :                                :  .    :. ::  *.:.    :   
Ankyrin 3D      -----------------------------------------t----tt---HHHHHHH--

Mbp1_ASPFU      AFRLVNLLLGHCP-RAGDLVNKKGETATSITQRAHLPEQNIPPPPSSITMGIDHT-----
Mbp1_ASPNI      VFRLVDLLLSRCP-RAGDLVNKRGETASSIMQRAHLAERDIPPPPSSITMGNDHI-----
Mbp1_ASPTE      AFRLVDILLTHCS-RAGDLVNKKGETAISITQRAHPSERDVPPPPSSVTMGNDHI-----
Mbp1_CRYNE      NKGLVGLLLDAGA-DK-TRANKLGLRPENFGLEI------EALKISNGEAVMANL-----
Mbp1_GIBZE      NRSIISQLLEVGA-DP-NIANRVGLRPLDFGIGSENAENKTNGEANVENGVVGTN-----
Mbp1_MAGGR      NRSIISQLLEVCA-SP-HIANRSGLRPTDFGIGVDSDGAMKTKGDSGGDVENGDV-----
Mbp1_NEUCR      NRSIISQLLEVGA-DP-TIPNRANLKPLDFGIGIADAETNDDPAQEKTGATTGSG-----
Mbp1_CANAL      NKKCIKVFINYHRFINFGLRNLVSCTVEDYLASHNYVLRLDPVEHDQSNNSDGDE-----
Mbp1_DEBHA      NKKCIKVFISYHKYINFHLKNLVSYTVEEYLASHNHVLRLDTSNDDSKEIQDIQEEAYKY
Mbp1_PICST      NKRCIKVFISYHKYIDFGLRNLVGYTVEDYLASHNYVLRLDQTGEEGEQEETEDL-----
Mbp1_CANGL      DREFFDILIKNGS-LS-TISNNDGQTPTEIMNQHYQDLHLQAQTNIAGSNTSAYTDSFSS
Mbp1_SACCE      DVVFFNTLVKMGA-LT-TISNKEGLTANEIMNQQYEQMMIQNGTNQHVNSSNTDLNIHVN
Mbp1_EREGO      DKKFFQTLVGNGA-LS-TIKNHDGVTADELINNRFVKTIQPTQRGNYHENRASHS-----
Mbp1_KLULA      DDQFYQLLLQNGA-LT-TVQNNSGMTPNGIISGRYSMDEITKGQRLDDPYEFNKM-----
Mbp1_YARLI      AKKVSRALMDFNV-KT-DIVNADGRTALDLLEGDRQMQQHPPPAMALHHQPPYQM-----
Mbp1_COPCI      SKRLVKLLIDHGA-DP-KINNHDGKNAEDYILEDERFRSSPAPSSRVAAMSYRNA-----
Mbp1_USTMA      SKRLVRLLLEHGA-DP-KIRNKEGKNAEDYIIEDERFRSSPSRTGPAGIELGADG-----
Mbp1_SCHPO      AMDCVNSLLSYNA-NP-SIPNRQRRTASEYLLEADKKPHSLLQSNSNASHSAFSF-----
                       ::           *                                       
Ankyrin 3D      -HHHHHHHH--t--tt-----t----HHHHHHHH--HHHHH-t--HHH-t----HHHHHH

Mbp1_ASPFU      ------EGDLTVLETPD------------QTDALPAEASLATSALLAKISAIMAETNKKL
Mbp1_ASPNI      ------DGEVGAPTSLEP-----------QSVTLHHESSPATAQLLSQIGAIMAEASRKL
Mbp1_ASPTE      ------DGEVNTSTNPDN-----------QSVAITPDTSSVTATLLSKIGVIIAEANKKL
Mbp1_CRYNE      -----------------------------------KSEVSKPERKSRDVQKNIATIFESI
Mbp1_GIBZE      ---------------------------------------QRSRESSDEIVASISHLLSET
Mbp1_MAGGR      -----------------------------------GGSSQKSNESSNEIVTSITHLLTET
Mbp1_NEUCR      ---------------------------------------HKSRETSDEVVRSITHLIGES
Mbp1_CANAL      --------DIMEDYTNEN-----------QSFETQLHNSKMAINLQNTTANLLTEKMTQL
Mbp1_DEBHA      LNPQFQGNNLTIRNNST------------QSFESQMYFSKMAVNLQNTTANLITEKLTEL
Mbp1_PICST      ---------LYSQEAVST-----------QSFESQLYYSKVAVNLQNTTSNLITERLTEL
Mbp1_CANGL      FGGKVKGSKLHSISELDDDKNTQNPENTVTNIVSNLHFSSNAAINLVKNIPAFTDSMKHL
Mbp1_SACCE      TNNIETKNDVNSMVIMSP-----------VSPSDYITYPSQIATNISRNIPNVVNSMKQM
Mbp1_EREGO      ----PLNSASAAGGMVPA-----------SLIHTGDMYPSQSATSVSRAIPEVINLMKDM
Mbp1_KLULA      -------------------------------------YPSQAATRTNRIIPEVINMMKEM
Mbp1_YARLI      ------------------------------------LHESETAIAAHNLAGTVVHNLQVL
Mbp1_COPCI      QVAYPPPGAPSTYSFAPA-----------NHDRPPLHYSAAAQKASTRCVNDMASMLDSL
Mbp1_USTMA      ----------------LP-----------VLPTSSLHTSEAGQRTAGRAVTLMSNLLHSL
Mbp1_SCHPO      -----------------------------SGISPAIISPSCSSHAFVKAIPSISSKFSQL
                                                                    .       
Ankyrin 3D      H--tHHHHHHHHHH---t------------------tt----HHHHHHH---HHHHHHHH

Mbp1_ASPFU      AACYGHTKSNEPVSDDVANPEALYEQLEVDRQKIQEQTAALE-----------AKETEGE
Mbp1_ASPNI      TSSYGAAKPSQKDSDDVANPEALYEQLEQDRQKIRRQYDALA-----------AKEAAEE
Mbp1_ASPTE      AVSYGSSKPGQQGSDDIANPEALYDQLELDRQKIKQQTAALS-----------AKEAEEE
Mbp1_CRYNE      SSTFSSEMLAKQ--TKLNATEASVRHATRALADKRQHLHRAQ-----------EKLATMQ
Mbp1_GIBZE      GSTFQSEMKAKQ--ASLDTLHSTLRTTSTQLGEARRSLEHLS-----------ATLKKQQ
Mbp1_MAGGR      SANFQEEIKNKQ--KNIDSLHATLRLTTTDVNDLRRKLDEAQ-----------ARVKAQQ
Mbp1_NEUCR      ASIFQNELKKKQ--ESIDTLHSQLRVTSSQVGDARRTLESLQ-----------EKLKAQQ
Mbp1_CANAL      AYAIDSELSEKD--EVILTYFKVLSQINQIKLESQRKILSFFKLDHLIEELEQNKDDSQQ
Mbp1_DEBHA      AYIVDKELSEKD--EKLLMYFKLLKAIGHEKLLSQRAVLQFF-----------KLEYLID
Mbp1_PICST      AYTIDKELSEKD--ETILTFFKILKSINTEKLVSQKAILSFF-----------KLEYLIE
Mbp1_CANGL      AEKFDGSYKNHE--ESCRSTEKMLGSIKRTVHSTDNRIREIL-----------ETDADAD
Mbp1_SACCE      ASIYNDLHEQHD--NEIKSLQKTLKSISKTKIQVSLKTLEVLKESSKDE----NGEAQTN
Mbp1_EREGO      ADSYQFLYEDRN--QEVQDLVKMLKSMSATVTSLDMKVLEIL-----------EVKDMNN
Mbp1_KLULA      ANSYQNAYQKRQ--NEVLQMERTVKSMKKTITSVEMKLLEAL-----------NLKETDN
Mbp1_YARLI      AHAFDAELKEKD--ADVQQVRQMATKMEEDIAATNEAIREYE------------------
Mbp1_COPCI      AASFDQELRDKE--RDMAQAQALLTNIQAEILESQRTVLQLR-----------QQAEGLS
Mbp1_USTMA      ADSYDSEINTAE--KKLTQAHGLLKQIQTEIEDSAKVAEALH--------------HEAQ
Mbp1_SCHPO      AEEYESQLREKE--EDLIRANRLKQDTLNEISRTYQELTFLQ-----------KNNPTYS
Annotation       CCCCCCCCCCC--CCCCCCCCCCCC
                                                                            

Mbp1_ASPFU      -----PVEAQLERYE------RLR--------------STYESLLEQ-------IQQVRL
Mbp1_ASPNI      -----SSDAQLGRYE------QMR--------------DNYESLLEQ-------IQRARL
Mbp1_ASPTE      -----PVDTQLARYE------QLR--------------ASYESLLEH-------IQQARL
Mbp1_CRYNE      -----LFEQRSENVR------RIMDAIAAGTLLTPAEFTGRTQTMHE----KSTGQLPPL
Mbp1_GIBZE      -----LAKQKVANLS------HARE-------------AEQVRLMQE----QSRASQPNP
Mbp1_MAGGR      -----LARQKVTNLQ------RAEE-------------RERYRLTQ--------LEQTTG
Mbp1_NEUCR      -----LAKQKIVNFN------RAC--------------EEEEQILIE-------LEQRHG
Mbp1_CANAL      QQQQVTDDDDPTSVHGNDLHLDFKRDHILQEEIYRLMNDLTYQELHQ----QDELDKVEH
Mbp1_DEBHA      DIMADYDQNNSDNLI-----IDTEKDRIIQDEINRLISDLSFQFLQR----KDQLDQVFM
Mbp1_PICST      DLERVNKETNPQELS-----LDFKRDQIIQDEIHRLINDLTYQFLQK----KEDLYQLHQ
Mbp1_CANGL      ISSAILAQEKDITEL------KIEA-------------ENHLRKLKN----QFEYLQKQR
Mbp1_SACCE      DDFEILSRLQEQNTK------KLRKRL-----------IRYKRLIKQ----KLEYRQTVL
Mbp1_EREGO      --ITYEMDSLKENIA------GLKQKL-----------SEKQKVLVS----LLEKSQRVT
Mbp1_KLULA      --VDIVLNDRKEKID------ELQRRI-----------ATDKRVLIN----RLEEGQVKL
Mbp1_YARLI      -----AKHGTAEELE------KLAS-------------EAEERVTTR-------VNQLRK
Mbp1_COPCI      QAKQRLADLENALQD------KMGRRYRLGFEKWIKDEETREKVIRDAANGDLVLTPATT
Mbp1_USTMA      -----GVDEERKRVD------SLQLALKHAINKRARD-DLERRWSEG----KQAIKRARL
Mbp1_SCHPO      QSMENLIREAQETYQ------QLSKRLLIWLEARQI--FDLERSLKP----HTSLSISFP
Annotation                           xxxxxx-----------xxxxxxxxx----xx
                                                                            

Mbp1_ASPFU      KERLTSMPPPAK-----------ENMMPSSSDQNQLLITYQLARQ--------------L
Mbp1_ASPNI      KERLASTPVPTQT----------AVIGSSSPEQDRLLTTFQLSRA--------------L
Mbp1_ASPTE      KERVASMPIPT------------KEQAESSKDTSQLTTVFQLAQK--------------L
Mbp1_CRYNE      AFRHVPGLALDASSQ--------SQLNGAPPSTPLSVEDQEDIALPERDDP--------E
Mbp1_GIBZE      SSSWETELS--------------AMLEAADDTSDGEFGGEGLLPS--------------A
Mbp1_MAGGR      RRDIASANGWEAESN--------TLLATINATTNGEPDADAKLPS--------------S
Mbp1_NEUCR      RLDVASANAWEMELESA------LEIVKTQSPKGLDPDSRPSLPS--------------A
Mbp1_CANAL      SYRMTKERLHEKVLDAS------SFVIDQTHQQGNVHEQLELAKQ--------------L
Mbp1_DEBHA      KYKAISSAIQNTKVAELAST---LSQHESNSSSTEDETPSEQVRLSIELQTQIVKYKQML
Mbp1_PICST      KYILVNEKV--------------QLTEEIIKCKKLSQQLYKQQMV--------------V
Mbp1_CANGL      LLKLTE-----------------YHNGEHNDTDNTLDNKIEICKQ--------------I
Mbp1_SACCE      LNKLIEDETQ-------------ATTNNTVEKDNNTLERLELAQE--------------L
Mbp1_EREGO      LRKCVEEEKKAIESV--------IAAPADDATHSSKETLADDLRE--------------L
Mbp1_KLULA      IRKFVDEET--------------KNVEGKTTDGEESEDIEALLKE--------------L
Mbp1_YARLI      VFERSQAKGLAML----------VAEEEREISREQTKGEFKTAKE--------------L
Mbp1_COPCI      SYTVDEDGDSDSGSNGDKNKGKRKAQVQQEEVSDLVELYSNIPTDPEELRKQCEALREEV
Mbp1_USTMA      QAGLEPGALSTSNATN-------APATGDQKSKDDAKSLIEALPAGTNVKTAIAELRKQL
Mbp1_SCHPO      SDFLKKEDGLSLNN---------DFKKPACNNVTNSDEYEQLINK--------------L
                                                                            

Mbp1_ASPFU      CSLQKAR-------------RAAVRDLAQQTADAGVS---------------TKFDVHRR
Mbp1_ASPNI      CSEQKIR-------------RAAVKELAQQRADAGVS---------------TKFDVHRK
Mbp1_ASPTE      CAAQKAR-------------RAAVKELAQQTADAGVS---------------TKFDVHRK
Mbp1_CRYNE      CLVKLRR-------------MALWEDRIAEVLEDKIR--------AMEGEGVDRAVKYRK
Mbp1_GIBZE      AVLEARV-------------RAVKKRCESTRKMVSAL----------KGRSRDTEVKYRR
Mbp1_MAGGR      ALLRARI-------------EAVKKQTESTRQSVVAL----------KGRSREVEGRYRH
Mbp1_NEUCR      AVLRARI-------------KALRARSSKTRQAVAAL----------QAQSKEKELKYRR
Mbp1_CANAL      QVEIIKR-------------KKLVDEISKLTKNVPLPENPNAKTIIDTYPSTDKLYKYCK
Mbp1_DEBHA      HKLHQQHLQVPLSSLNDNTDTKENKENIKEESQTNDTAEPAPHSVIAKYPKDDKLHKYCK
Mbp1_PICST      PIPQTSI-------------DKENNSTPTGSSSNSIV---------AKYPHDNLLSKYCH
Mbp1_CANGL      SVLQIER-------------KRKISELISHYEDS------------------RKIHKYRR
Mbp1_SACCE      TMLQLQR-------------KNKLSSLVKKFEDN------------------AKIHKYRR
Mbp1_EREGO      TVLQLRR-------------KHKINRLIELLCGN------------------SKIHKFRK
Mbp1_KLULA      VLIQLKR-------------KRKLNQIIDVITDN------------------SKVYKYRK
Mbp1_YARLI      TDLQHGR-------------KDLVDDVVELFANAGVG---------------EKMNEYRR
Mbp1_COPCI      SQSRKRR-------------KAMFDELVTFQAEAGTS---------------GRMSDYRR
Mbp1_USTMA      SQVQANK-------------TELVDKFVARAREQGTG---------------RTMAAYRR
Mbp1_SCHPO      TSLQASR-------------KKDTLYIRKLYEELGID---------------DTVNSYRR
                                                                         . .

Mbp1_ASPFU      LVALAT-GLKEEELD-PMAAELAETLEFDRMNGRGPG-----------------------
Mbp1_ASPNI      LVALAT-GLKEEELD-PMAAELAETLEFDRMNGKGVG-----------------------
Mbp1_ASPTE      LVALAT-GLKEEELD-PMAAELAEALEFDRMNGKGNG-----------------------
Mbp1_CRYNE      LVSVCA-KVPVDKVD-SMLDGLVAAVESEGQGLDFSR-----------------------
Mbp1_GIBZE      VVALCT-GVQEDEVD-AVIDGLLKAVESEQEELEINR-----------------------
Mbp1_MAGGR      LVALAT-KCRDEDVD-STMEGLLKAVESEKGELEIGR-----------------------
Mbp1_NEUCR      LVSLCT-RRPEIEVE-ALLDTLTRAVESEKPELEIAR-----------------------
Mbp1_CANAL      LISLSC-GIPMDEIE-TSIDAMEESLVKK-------------------------------
Mbp1_DEBHA      LIALCC-GMNFNDVE-NSIDLIEQSLSKSAPNMQ--------------------------
Mbp1_PICST      LIAQCC-GMDFDDVE-GSIDEIEQSLLKSNVK----------------------------
Mbp1_CANGL      MISEGT-EMKTEEVD-GCLDIILQTLINNSS-----------------------------
Mbp1_SACCE      IIREGT-EMNIEEVD-SSLDVILQTLIANNNKNKGAE-----------------------
Mbp1_EREGO      MISQGT-DMDISEVD-NFLDVIFQQLNEDEENTNNGG-----------------------
Mbp1_KLULA      MISQGT-DIDVSDVD-ECLDVIYQTLSKEG------------------------------
Mbp1_YARLI      LVAMSC-GVKVEDID-GLLDGIEKALLEGER-----------------------------
Mbp1_COPCI      LIAAGCGGLEPLEID-SVLGMLLETLEAEDPSSTSAT-----------------------
Mbp1_USTMA      LIAAGCGGIAPDEVD-AVVGVLCELLQESHTGARAGAGGERDDRARDVAMMLKAFPVYSR
Mbp1_SCHPO      LIAMSC-GINPEDLSLEILDAVEEALTREK------------------------------
                ::          .:.      :   :                                  

Mbp1_ASPFU      ------------------------------------------------------------
Mbp1_ASPNI      ------------------------------------------------------------
Mbp1_ASPTE      ------------------------------------------------------------
Mbp1_CRYNE      ------------------------------------------------------------
Mbp1_GIBZE      ------------------------------------------------------------
Mbp1_MAGGR      ------------------------------------------------------------
Mbp1_NEUCR      ------------------------------------------------------------
Mbp1_CANAL      ------------------------------------------------------------
Mbp1_DEBHA      ------------------------------------------------------------
Mbp1_PICST      ------------------------------------------------------------
Mbp1_CANGL      ------------------------------------------------------------
Mbp1_SACCE      ------------------------------------------------------------
Mbp1_EREGO      ------------------------------------------------------------
Mbp1_KLULA      ------------------------------------------------------------
Mbp1_YARLI      ------------------------------------------------------------
Mbp1_COPCI      ------------------------------------------------------------
Mbp1_USTMA      CIVMNRQLAVTRYPCCRLLFYSLPCRTNMISGLWMQSDSVAAVLARSNAVLRISPCPKCA
Mbp1_SCHPO      ------------------------------------------------------------
                                                                            

Mbp1_ASPFU      ------------------------------------------------------------
Mbp1_ASPNI      ------------------------------------------------------------
Mbp1_ASPTE      ------------------------------------------------------------
Mbp1_CRYNE      ------------------------------------------------------------
Mbp1_GIBZE      ------------------------------------------------------------
Mbp1_MAGGR      ------------------------------------------------------------
Mbp1_NEUCR      ------------------------------------------------------------
Mbp1_CANAL      ------------------------------------------------------------
Mbp1_DEBHA      ------------------------------------------------------------
Mbp1_PICST      ------------------------------------------------------------
Mbp1_CANGL      ------------------------------------------------------------
Mbp1_SACCE      ------------------------------------------------------------
Mbp1_EREGO      ------------------------------------------------------------
Mbp1_KLULA      ------------------------------------------------------------
Mbp1_YARLI      ------------------------------------------------------------
Mbp1_COPCI      ------------------------------------------------------------
Mbp1_USTMA      RMSKLQAHLYEASAARLCGGKMLRRTLALFSEAARSSSSSSASAAASSSASILTSHLSKA
Mbp1_SCHPO      ------------------------------------------------------------
                                                                            

Mbp1_ASPFU      ------------------------------------------------------------
Mbp1_ASPNI      ------------------------------------------------------------
Mbp1_ASPTE      ------------------------------------------------------------
Mbp1_CRYNE      ------------------------------------------------------------
Mbp1_GIBZE      ------------------------------------------------------------
Mbp1_MAGGR      ------------------------------------------------------------
Mbp1_NEUCR      ------------------------------------------------------------
Mbp1_CANAL      ------------------------------------------------------------
Mbp1_DEBHA      ------------------------------------------------------------
Mbp1_PICST      ------------------------------------------------------------
Mbp1_CANGL      ------------------------------------------------------------
Mbp1_SACCE      ------------------------------------------------------------
Mbp1_EREGO      ------------------------------------------------------------
Mbp1_KLULA      ------------------------------------------------------------
Mbp1_YARLI      ------------------------------------------------------------
Mbp1_COPCI      ------------------------------------------------------------
Mbp1_USTMA      HLPPSLARSAKPHKNLYQMLSTLPKDGVGARVRQRRWAAKGLDVSHDVDLKAHLAKLHHT
Mbp1_SCHPO      ------------------------------------------------------------
                                                                            

Mbp1_ASPFU      -GESPEPVQKRLPSQREPSSLPFSGPPVSVDA----------------------------
Mbp1_ASPNI      -------PESPEADHKDSASLPFPGPVVSVDA----------------------------
Mbp1_ASPTE      -------AESPDLEHKDSASFPFPEPTISVDA----------------------------
Mbp1_CRYNE      -------------------ASNFVNRIKATKS----------------------------
Mbp1_GIBZE      -------------------VRRFLGGVEGVQ-----------------------------
Mbp1_MAGGR      -------------------VRRFLGGVEGVIG----------------------------
Mbp1_NEUCR      -------------------VRRFLGGVEGVVH----------------------------
Mbp1_CANAL      ------------------------------------------------------------
Mbp1_DEBHA      ------------------------------------------------------------
Mbp1_PICST      ------------------------------------------------------------
Mbp1_CANGL      ------------------------------------------------------------
Mbp1_SACCE      -------------------QIITISNANSHA-----------------------------
Mbp1_EREGO      -------------------HTNYNGHVSCAILDTVEGYGIENIENKRGTSQNDGPAK---
Mbp1_KLULA      ------------------------------------------------------------
Mbp1_YARLI      ------------------------------------------------------------
Mbp1_COPCI      ----------------------WSGSKGQQTG----------------------------
Mbp1_USTMA      GATKTNKDEGHLCYWEITKVRLKDGGNHGKAWGRFVWRERNAGVVKQGQAQAKLTKVCLS
Mbp1_SCHPO      ------------------------------------------------------------
                                                                            

Mbp1_ASPFU      -------------------------------
Mbp1_ASPNI      -------------------------------
Mbp1_ASPTE      -------------------------------
Mbp1_CRYNE      -------------------------------
Mbp1_GIBZE      -------------------------------
Mbp1_MAGGR      -------------------------------
Mbp1_NEUCR      -------------------------------
Mbp1_CANAL      -------------------------------
Mbp1_DEBHA      -------------------------------
Mbp1_PICST      -------------------------------
Mbp1_CANGL      -------------------------------
Mbp1_SACCE      -------------------------------
Mbp1_EREGO      -------------------------------
Mbp1_KLULA      -------------------------------
Mbp1_YARLI      -------------------------------
Mbp1_COPCI      -------------------------------
Mbp1_USTMA      MVVAHPGKPITKAESGERIPGALKYCWDLAH
Mbp1_SCHPO      -------------------------------