Difference between revisions of "Lecture 18"
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| + | <div style="padding: 5px; background: #FF4560; border:solid 2px #000000;"> | ||
| + | '''Update Warning!''' | ||
| + | This page has not been revised yet for the 2007 Fall term. Some of the slides may be reused, but please consider the page as a whole out of date as long as this warning appears here. | ||
| + | </div> | ||
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__NOTOC__ | __NOTOC__ | ||
<small>[[Lecture_17|(Previous lecture)]] ... [[Lecture_19|(Next lecture)]]</small> | <small>[[Lecture_17|(Previous lecture)]] ... [[Lecture_19|(Next lecture)]]</small> | ||
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==Clinical Genomics== | ==Clinical Genomics== | ||
| − | Clinical Genomics is the application of genome information to our understanding of human disease. (Do not confuse with Clinical Genetics - i.e. | + | Clinical Genomics is the application of genome information to our understanding of human disease. (Do not confuse with Clinical Genetics - i.e. genetic counseling). |
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======Slide 003====== | ======Slide 003====== | ||
[[Image:L18_s003.jpg|frame|none|Lecture 18, Slide 003<br> | [[Image:L18_s003.jpg|frame|none|Lecture 18, Slide 003<br> | ||
| + | (*) see [http://www.nature.com/nature/journal/v444/n7118/full/nature05329.html Redon ''et al.'' (2006) Nature '''444''':444-454] | ||
| + | ]] | ||
| − | |||
======Slide 004====== | ======Slide 004====== | ||
[[Image:L18_s004.jpg|frame|none|Lecture 18, Slide 004<br> | [[Image:L18_s004.jpg|frame|none|Lecture 18, Slide 004<br> | ||
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======Slide 016====== | ======Slide 016====== | ||
[[Image:L18_s016.jpg|frame|none|Lecture 18, Slide 016<br> | [[Image:L18_s016.jpg|frame|none|Lecture 18, Slide 016<br> | ||
| + | All integrated bioinformatics resources cross reference SNP information. It is often quite a challenge to wade through the large amounts of information that are being offered. Example: BRCA-2 gene | ||
| + | ]] | ||
| − | |||
======Slide 017====== | ======Slide 017====== | ||
[[Image:L18_s017.jpg|frame|none|Lecture 18, Slide 017<br> | [[Image:L18_s017.jpg|frame|none|Lecture 18, Slide 017<br> | ||
| + | Example: BRCA-2 gene in ensembl (note: SNPs only displayed for <50 kb long regions) | ||
| + | ]] | ||
| − | |||
======Slide 018====== | ======Slide 018====== | ||
[[Image:L18_s018.jpg|frame|none|Lecture 18, Slide 018<br> | [[Image:L18_s018.jpg|frame|none|Lecture 18, Slide 018<br> | ||
| + | Example: BRCA-2 gene - SNP from search results for NP_000050 in dbSNP | ||
| + | ]] | ||
| − | |||
======Slide 019====== | ======Slide 019====== | ||
[[Image:L18_s019.jpg|frame|none|Lecture 18, Slide 019<br> | [[Image:L18_s019.jpg|frame|none|Lecture 18, Slide 019<br> | ||
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======Slide 028====== | ======Slide 028====== | ||
[[Image:L18_s028.jpg|frame|none|Lecture 18, Slide 028<br> | [[Image:L18_s028.jpg|frame|none|Lecture 18, Slide 028<br> | ||
| − | + | As in so many examples we have looked at: the future lies in the '''intelligent integration of evidence'''. | |
]] | ]] | ||
Latest revision as of 15:29, 1 September 2007
Update Warning! This page has not been revised yet for the 2007 Fall term. Some of the slides may be reused, but please consider the page as a whole out of date as long as this warning appears here.
(Previous lecture) ... (Next lecture)
Clinical Genomics
Clinical Genomics is the application of genome information to our understanding of human disease. (Do not confuse with Clinical Genetics - i.e. genetic counseling).
...
Add:
- Summary points
- Exercises
- Further reading
Lecture Slides
Slide 001
Lecture 18, Slide 001
Slide 002
Lecture 18, Slide 002
Slide 003
Lecture 18, Slide 003
(*) see Redon et al. (2006) Nature 444:444-454
(*) see Redon et al. (2006) Nature 444:444-454
Slide 004
Lecture 18, Slide 004
Slide 005
Lecture 18, Slide 005
Slide 006
Lecture 18, Slide 006
Slide 007
Lecture 18, Slide 007
Slide 008
Lecture 18, Slide 008
Slide 009
Lecture 18, Slide 009
Slide 010
Lecture 18, Slide 010
Slide 011
Lecture 18, Slide 011
Slide 012
Lecture 18, Slide 012
Slide 013
Lecture 18, Slide 013
Slide 014
Lecture 18, Slide 014
Slide 015
Lecture 18, Slide 015
Slide 016
Lecture 18, Slide 016
All integrated bioinformatics resources cross reference SNP information. It is often quite a challenge to wade through the large amounts of information that are being offered. Example: BRCA-2 gene
All integrated bioinformatics resources cross reference SNP information. It is often quite a challenge to wade through the large amounts of information that are being offered. Example: BRCA-2 gene
Slide 017
Lecture 18, Slide 017
Example: BRCA-2 gene in ensembl (note: SNPs only displayed for <50 kb long regions)
Example: BRCA-2 gene in ensembl (note: SNPs only displayed for <50 kb long regions)
Slide 018
Lecture 18, Slide 018
Example: BRCA-2 gene - SNP from search results for NP_000050 in dbSNP
Example: BRCA-2 gene - SNP from search results for NP_000050 in dbSNP
Slide 019
Lecture 18, Slide 019
Slide 020
Lecture 18, Slide 020
Slide 021
Lecture 18, Slide 021
Slide 022
Lecture 18, Slide 022
Slide 023
Lecture 18, Slide 023
Slide 024
Lecture 18, Slide 024
Slide 025
Lecture 18, Slide 025
Slide 026
Lecture 18, Slide 026
Slide 027
Lecture 18, Slide 027
Slide 028
Lecture 18, Slide 028
As in so many examples we have looked at: the future lies in the intelligent integration of evidence.
As in so many examples we have looked at: the future lies in the intelligent integration of evidence.
