Difference between revisions of "BIN-ALI-Dotplot"

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m (Created page with "<div id="BIO"> <div class="b1"> Dotplot </div> {{Vspace}} <div class="keywords"> <b>Keywords:</b>  Computation and interpretation of dotplots </div> {{Vspace}}...")
 
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<div id="ABC">
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<div style="padding:5px; border:1px solid #000000; background-color:#f2fafa; font-size:300%; font-weight:400; color: #000000; width:100%;">
 
Dotplot
 
Dotplot
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<div style="padding:5px; margin-top:20px; margin-bottom:10px; background-color:#f2fafa; font-size:30%; font-weight:200; color: #000000; ">
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(Computation and interpretation of dotplots)
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  {{Vspace}}
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</div>
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<div class="keywords">
 
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<b>Keywords:</b>&nbsp;
 
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Computation and interpretation of dotplots
 
 
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</div>
  
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{{Smallvspace}}
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__TOC__
 
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{{STUB}}
 
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<div style="padding:5px; border:1px solid #000000; background-color:#f2fafa33; font-size:85%;">
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<div style="font-size:118%;">
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<b>Abstract:</b><br />
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<section begin=abstract />
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...
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<div id="ABC-unit-framework">
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<!-- ============================  -->
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== Abstract ==
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<hr>
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<table>
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<td style="padding:10px;">
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<b>Objectives:</b><br />
 
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<td style="padding:10px;">
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<b>Outcomes:</b><br />
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== This unit ... ==
 
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=== Prerequisites ===
 
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<!-- included from "../components/BIN-ALI-Dotplot.components.wtxt", section: "prerequisites" -->
 
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<!-- included from "ABC-unit_components.wtxt", section: "notes-prerequisites" -->
 
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You need to complete the following units before beginning this one:
 
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*[[BIN-ALI-Similarity]]
 
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=== Objectives ===
 
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...
 
...
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</td>
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<!-- ============================  -->
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<hr>
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<b>Deliverables:</b><br />
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<li><b>Time management</b>: Before you begin, estimate how long it will take you to complete this unit. Then, record in your course journal: the number of hours you estimated, the number of hours you worked on the unit, and the amount of time that passed between start and completion of this unit.</li>
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<li><b>Journal</b>: Document your progress in your [[FND-Journal|Course Journal]]. Some tasks may ask you to include specific items in your journal. Don't overlook these.</li>
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<li><b>Insights</b>: If you find something particularly noteworthy about this unit, make a note in your [[ABC-Insights|'''insights!''' page]].</li>
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<section end=deliverables />
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<!-- ============================  -->
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<hr>
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<section begin=prerequisites />
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<b>Prerequisites:</b><br />
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This unit builds on material covered in the following prerequisite units:<br />
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*[[BIN-ALI-Similarity|BIN-ALI-Similarity (Measuring Sequence Similarity)]]
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<section end=prerequisites />
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<!-- ============================  -->
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</div>
  
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=== Outcomes ===
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{{STUB}}
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...
 
  
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{{Smallvspace}}
  
  
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=== Deliverables ===
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__TOC__
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<!-- included from "../components/BIN-ALI-Dotplot.components.wtxt", section: "deliverables" -->
 
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<!-- included from "ABC-unit_components.wtxt", section: "deliverables-time_management" -->
 
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*<b>Time management</b>: Before you begin, estimate how long it will take you to complete this unit. Then, record in your course journal: the number of hours you estimated, the number of hours you worked on the unit, and the amount of time that passed between start and completion of this unit.
 
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<!-- included from "ABC-unit_components.wtxt", section: "deliverables-journal" -->
 
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*<b>Journal</b>: Document your progress in your [[FND-Journal|course journal]].
 
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<!-- included from "ABC-unit_components.wtxt", section: "deliverables-insights" -->
 
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*<b>Insights</b>: If you find something particularly noteworthy about this unit, make a note in your [[ABC-Insights|insights! page]].
 
  
 
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=== Evaluation ===
 
=== Evaluation ===
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<!-- included from "../components/BIN-ALI-Dotplot.components.wtxt", section: "evaluation" -->
 
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<b>Evaluation: NA</b><br />
 
<b>Evaluation: NA</b><br />
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:This unit is not evaluated for course marks.
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<div style="margin-left: 2rem;">This unit is not evaluated for course marks.</div>
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</div>
 
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<div id="BIO">
 
 
== Contents ==
 
== Contents ==
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<!-- included from "../components/BIN-ALI-Dotplot.components.wtxt", section: "contents" -->
 
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...
 
  
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{{Task|1=
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*Read the introductory notes on {{ABC-PDF|BIN-ALI-Dotplot|Dotplots for sequence comparison}}.
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}}
  
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<!--
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=== DotPlots and the Mutation Data Matrix ===
  
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== Further reading, links and resources ==
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Before we start calculating alignments, we should get a better sense of the underlying sequence similarity. A Dotplot is a perfect tool for that, because it displays alignment-free similarity information. (For a deeper introduction into dotplots, see the [[BIN-ALI-Dotplot|Dotplots learning unit]]). Let's make a dotplot that uses the BLOSUM62 Mutation Data Matrix to measure pairwise amino acid similarity. The NCBI makes its alignment matrices available by ftp. They are located at  ftp://ftp.ncbi.nih.gov/blast/matrices - for example here is a link to the [ftp://ftp.ncbi.nih.gov/blast/matrices/BLOSUM62 '''BLOSUM62 matrix''']<ref>That directory also contains sourcecode to generate the PAM matrices. This may be of interest if you ever want to produce scoring matrices from your own datasets.</ref>.
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<!-- {{#pmid: 19957275}} -->
 
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<!-- <div class="reference-box">[http://www.ncbi.nlm.nih.gov]</div> -->
 
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-->
  
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== Notes ==
 
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<!-- included from "../components/BIN-ALI-Dotplot.components.wtxt", section: "notes" -->
 
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<references />
 
  
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== Self-evaluation ==
 
== Self-evaluation ==
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=== Question 1===
 
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== Further reading, links and resources ==
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<!-- {{#pmid: 19957275}} -->
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<!-- {{WWW|WWW_GMOD}} -->
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<!-- <div class="reference-box">[http://www.ncbi.nlm.nih.gov]</div> -->
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== Notes ==
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<references />
  
 
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<b>If in doubt, ask!</b> If anything about this learning unit is not clear to you, do not proceed blindly but ask for clarification. Post your question on the course mailing list: others are likely to have similar problems. Or send an email to your instructor.
 
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Latest revision as of 09:26, 25 September 2020

Dotplot

(Computation and interpretation of dotplots)


 


Abstract:

...

Objectives:
...

Outcomes:
...

Deliverables:

  • Time management: Before you begin, estimate how long it will take you to complete this unit. Then, record in your course journal: the number of hours you estimated, the number of hours you worked on the unit, and the amount of time that passed between start and completion of this unit.
  • Journal: Document your progress in your Course Journal. Some tasks may ask you to include specific items in your journal. Don't overlook these.
  • Insights: If you find something particularly noteworthy about this unit, make a note in your insights! page.

    • Prerequisites:
    This unit builds on material covered in the following prerequisite units:


     


    Sorry!

    This page is only a stub; it is here as a placeholder to establish the logical framework of the site but there is no significant content as yet. Do not work with this material until it is updated to "live" status.


     



     


    Evaluation

    Evaluation: NA

    This unit is not evaluated for course marks.

    Contents

    Task:


    Self-evaluation

    Further reading, links and resources

    Notes


     


    About ...
     
    Author:

    Boris Steipe <boris.steipe@utoronto.ca>

    Created:

    2017-08-05

    Modified:

    2017-08-05

    Version:

    0.1

    Version history:

    • 0.1 First stub

    CreativeCommonsBy.png This copyrighted material is licensed under a Creative Commons Attribution 4.0 International License. Follow the link to learn more.

    Sorry!

    This page is only a stub; it is here as a placeholder to establish the logical framework of the site but there is no significant content as yet. Do not work with this material until it is updated to "live" status.

    Retrieved from "http://steipe.biochemistry.utoronto.ca/abc/index.php?title=BIN-ALI-Dotplot&oldid=11673"